1. Protein Tyrosine Kinase/RTK
    Autophagy
  2. ALK
    IGF-1R
    Autophagy

AZD-3463 (Synonyms: ALK/IGF1R inhibitor)

Cat. No.: HY-15609 Purity: 98.49%
Handling Instructions

AZD-3463 is an ALK/IGF1R inhibitor which overcomes multiple mechanisms of acquired resistance to crizotinib.

For research use only. We do not sell to patients.

AZD-3463 Chemical Structure

AZD-3463 Chemical Structure

CAS No. : 1356962-20-3

Size Price Stock Quantity
Free Sample (0.5-1 mg)   Apply now  
10 mM * 1 mL in DMSO USD 125 In-stock
Stock in the United States
Estimated Time of Arrival: December 31
5 mg USD 114 In-stock
Stock in Sweden
Estimated Time of Arrival: December 31
10 mg USD 180 In-stock
Stock in Sweden
Estimated Time of Arrival: December 31
50 mg USD 437 In-stock
Stock in Sweden
Estimated Time of Arrival: December 31
100 mg USD 638 In-stock
Stock in Sweden
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

  • Biological Activity

  • Protocol

  • Technical Information

  • Purity & Documentation

Description

AZD-3463 is an ALK/IGF1R inhibitor which overcomes multiple mechanisms of acquired resistance to crizotinib. IC50 Value: Target: ALK/IGF1R

Preparing Stock Solutions
Concentration Volume Mass 1 mg 5 mg 10 mg
1 mM 2.2274 mL 11.1371 mL 22.2742 mL
5 mM 0.4455 mL 2.2274 mL 4.4548 mL
10 mM 0.2227 mL 1.1137 mL 2.2274 mL
Please refer to the solubility information to select the appropriate solvent.
Molecular Weight

448.95

Formula

C₂₄H₂₅ClN₆O

CAS No.

1356962-20-3

SMILES

ClC(C=NC(NC1=C(OC)C=C(N2CCC(N)CC2)C=C1)=N3)=C3C4=CNC5=C4C=CC=C5

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

Solvent & Solubility

10 mM in DMSO

* "<1 mg/mL" means slightly soluble or insoluble. "≥" means soluble, but saturation unknown.

  • ALK/IGF1R inhibitor

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Product Name:
AZD-3463
Cat. No.:
HY-15609
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