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OXO

" in MedChemExpress (MCE) Product Catalog:

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By Research Areas:	Cancer (65) Cardiovascular Disease (6) Endocrinology (3) Infection (27) Inflammation/Immunology (32) Metabolic Disease (134) Neurological Disease (12)
Click Chemistry:	Alkynes (10)
Oligonucleotides:	Adenosine (1) Guanosine (16) Thymine (1) Nucleotide Analogs (3) Adenine (1) Other Phosphoramidite (3) Guanine (10) Guanine Nucleotide (1) Nucleoside Analogs (25) Uridine (1) Cytosine (1) Uracil (1) Phosphoramidites (17)

538

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Peptides

105

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Click Chemistry

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-118828

*12-Oxo* phytodienoic acid** 12-OPDA	NF-κB p38 MAPK	Neurological Disease Inflammation/Immunology
12-Oxo phytodienoic acid (12-OPDA) is a plant lipid-derived anti-inflammatory compound. 12-Oxo phytodienoic acid suppresses neuroinflammation by inhibiting Nf-κB and p38 MAPK signaling in Lipopolysaccharides (LPS) (HY-D1056)-activated cells. 12-Oxo phytodienoic acid can be used for neurodegenerative diseases research .

HY-112817

*8-Oxo-dGTP* 8-OXO-Deoxyguanosine triphosphate	Apoptosis	Cardiovascular Disease Neurological Disease Cancer
8-Oxo-dGTP (8-Oxo-Deoxyguanosine triphosphate) is an oxidized guanine nucleotide formed by ROS-mediated oxidative modification of dGTP, and it also serves as a key substrate for 8-oxo-dGTP pyrophosphohydrolases (such as hMTH1 and E. coli MutT). 8-Oxo-dGTP acts as a DNA mutagen, inserts into nascent DNA and pairs with adenine and cytosine, inducing A:T to C:G transversion mutations. Furthermore, 8-Oxo-dGTP causes oxidative DNA base modification, strand breakage and S-phase arrest, and ultimately triggers AIF-mediated apoptosis and promotes spontaneous carcinogenesis in mth1-deficient mice. Accumulation of 8-Oxo-dGTP in cells induces genomic instability, but it exhibits a tumor-suppressive effect that reduces tumor incidence in mouse models instead. 8-Oxo-dGTP is widely used in studies related to spontaneous carcinogenesis, Parkinson's disease, Alzheimer's disease, heart failure and tumor mechanisms .

HY-118828B

*12-Oxo* phytodienoic acid (≥90%)** 1 Publications Verification 12-OPDA (≥90%)	NF-κB p38 MAPK TNF Receptor Interleukin Related NO Synthase Keap1-Nrf2	Neurological Disease Inflammation/Immunology
12-Oxo phytodienoic acid (≥90%) (12-OPDA (≥90%)) is a plant lipid-derived anti-inflammatory compound. 12-Oxo phytodienoic acid (≥90%) induces the expression of SOCS-1 and inhibits LPS (HY-D1056)-induced activation of the NF-κB and p38 MAPK signaling pathways. 12-Oxo phytodienoic acid (≥90%) inhibits LPS-induced expression of IL-6 and TNF-α, and reduces LPS-induced NO production by decreasing iNOS levels. 12-Oxo phytodienoic acid (≥90%) induces activation of the Nrf2 signaling cascade. 12-Oxo phytodienoic acid (≥90%) can be used for the research of neurodegenerative diseases .

HY-N9945

*3-Oxo-7-hydroxychol-4-enoic acid*	Endogenous Metabolite	Inflammation/Immunology
3-Oxo-7-hydroxychol-4-enoic acid is an endogenous metabolite. 3-Oxo-7-hydroxychol-4-enoic acid may be an important indicator of a poor prognosis in hepatobiliary disease .

HY-114524

*(E)-4-Oxo-2-nonenal* 1 Publications Verification 4-ONE	TRP Channel	Cardiovascular Disease
(E)-4-Oxo-2-nonenal (4-ONE) is one of the major hemolytic decomposition products of lipid hydroperoxides. (E)-4-Oxo-2-nonenal is a major product of the FeII-mediated breakdown of lipid hydroperoxides. (E)-4-Oxo-2-nonenal is a potent transient receptor potential ankyrin 1 (TRPA1) agonist .

HY-W391635

*3-Oxo* deoxycholic acid**	Drug Metabolite	Metabolic Disease
3-oxo Deoxycholic acid is a secondary bile acid and a metabolite of Deoxycholic acid (HY-N0593) in C. perfringens .

HY-W767767

*2-Oxo-3-hydroxy-LSD-d10*	Isotope-Labeled Compounds Drug Metabolite	Neurological Disease
2-Oxo-3-hydroxy-LSD-d₁₀ is the deuterium labeled 2-Oxo-3-hydroxy-LSD (HY-137386). 2-Oxo-3-hydroxy-LSD is a metabolite of Lysergic acid diethylamide .

HY-N9944

*3-Oxo-4,6-choladien-24-oic acid*	Endogenous Metabolite	Metabolic Disease
3-Oxo-4,6-choladien-24-oic acid is an endogenous metabolite. 3-Oxo-4,6-choladien-24-oic acid exsists in the urine of patients with hepatobiliary disease .

HY-N9768

*(10E,12E)-9-Oxo-10,12-octadecadienoic acid* 9-OXO-ODA	Fungal PPAR	Infection
(10E,12E)-9-Oxo-10,12-octadecadienoic acid (9-oxo-ODA) is a PPARα agonist that can be isolated from the basidiomycete Gomphus floccosus. (10E,12E)-9-Oxo-10,12-octadecadienoic acid enhances fatty acid oxidation through PPARα activation, thereby inhibiting triglyceride accumulation. (10E,12E)-9-Oxo-10,12-octadecadienoic acid also has antifungal (Fungal) activity .

HY-W048995

*D-6-Oxo-pipecolinic acid*	Endogenous Metabolite	Neurological Disease
D-6-Oxo-pipecolinic acid is the D-enantiomer of 6-Oxo-pipecolinic acid. 6-Oxo-pipecolinic acid is the biomarkers associated with pyridoxine-dependent epilepsy (PDE-ALDH7A1) .

HY-118025

*(±)-2-Oxo* clopidogrel** (±)-SR-121683	Drug Metabolite	Others
(±)-2-Oxo clopidogrel is a metabolite of the antiplatelet agent Clopidogrel (HY-15283) .

HY-113457S

*11-Oxo* etiocholanolone-d5** 11-Ketoetiocholanolone-d₅	Isotope-Labeled Compounds Endogenous Metabolite Biochemical Assay Reagents	Metabolic Disease
11-Oxo etiocholanolone-d₅ (11-Ketoetiocholanolone-d₅) is the deuterium labeled 11-Oxo etiocholanolone (HY-113457). 11-Oxo etiocholanolone (11-Ketoetiocholanolone) is a steroid. 11-Oxo etiocholanolone is a key indicator for detecting cortisol metabolites in feces and urine. 11-Oxo etiocholanolone has the potential to be a pheromone .

HY-113457

*11-Oxo* etiocholanolone** 11-Ketoetiocholanolone	Endogenous Metabolite Biochemical Assay Reagents	Metabolic Disease
11-Oxo etiocholanolone (11-Ketoetiocholanolone) is a steroid. 11-Oxo etiocholanolone is a key indicator for detecting cortisol metabolites in feces and urine. 11-Oxo etiocholanolone has the potential to be a pheromone .

HY-165854

*12-Oxo-9(Z)-dodecenoic acid*	Biochemical Assay Reagents	Metabolic Disease
12-Oxo-9(Z)-dodecenoic acid is an ester product.

HY-W778270

*2-Oxo* clopidogrel-13C,d3 hydrochloride**	Isotope-Labeled Compounds	Others
2-Oxo clopidogrel- ¹³C,d₃ hydrochloride is the deuterium and ¹³C-labeled (±)-2-Oxo clopidogrel hydrochloride (HY-W585947).

HY-N16603

*16-Oxo-3-episerratenediol*	Others	Others
16-Oxo-3-episerratenediol is a type of triterpenoid compound that can be found in the Lycopodium clavatum .

HY-137386

*2-Oxo-3-hydroxy-LSD*	Drug Metabolite	Neurological Disease
2-Oxo-3-hydroxy-LSD is a metabolite of Lysergic acid diethylamide .

HY-116536

*N-3-Oxo-tetradecanoyl-L-homoserine lactone* OXO-C14-HSL	Bacterial	Infection
N-3-Oxo-tetradecanoyl-L-homoserine lactone (oxo-C14-HSL) is a rhizobacterial inducer and can improve basic defense against nematodes .

HY-N16228

*16-Oxo-octadecanoic acid*	Drug Derivative	Others
16-Oxo-octadecanoic acid is an octadecanoid.

HY-N5097

*13-Oxo-9E,11E-octadecadienoic acid*	PPAR	Metabolic Disease
13-Oxo-9E,11E-octadecadienoic acid, an isomer of 9-oxo-ODA, is a potent PPARα activator derived from tomato juice. 13-Oxo-9E,11E-octadecadienoic acid decreases plasma and hepatic triglyceride in obese diabetic mice .

HY-Z7657

Rosuvastatin impurity 10 5-OXO rosuvastatin	Drug Intermediate	Others
Rosuvastatin impurity 10 (5-Oxo rosuvastatin) is an impurity of Rosuvastatin.

HY-W850170

*12-Oxo-octadecanoic acid* 12-OXO stearic acid	Biochemical Assay Reagents	Metabolic Disease
12-Oxo-octadecanoic acid (12-Oxo stearic acid) is an ester product.

HY-135381

*3-Oxo* Atorvastatin**	Drug Metabolite	Cardiovascular Disease
3-Oxo Atorvastatin is an impurity of 3-Oxo Atorvastatin. Atorvastatin is an orally active HMG-CoA reductase inhibitor and has the ability to effectively decrease blood lipids .

HY-W351110

*(3-Oxo-3-phenylpropyl)glycine*	Biochemical Assay Reagents	Metabolic Disease
(3-Oxo-3-phenylpropyl)glycine is an ester product.

HY-CE01171

*3-Oxo-27-methyloctacosanoyl-CoA* 3-OXO-27-methyloctacosanoyl-coenzyme A	Biochemical Assay Reagents	Metabolic Disease
3-Oxo-27-methyloctacosanoyl-CoA (3-Oxo-27-methyloctacosanoyl-coenzyme A) is a derivative of coenzyme A .

HY-CE01147

*3-Oxo-17-methyloctadecanoyl-CoA* 3-OXO-17-methyloctadecanoyl-coenzyme A	Biochemical Assay Reagents	Metabolic Disease
3-Oxo-17-methyloctadecanoyl-CoA (3-Oxo-17-methyloctadecanoyl-coenzyme A) is a derivative of coenzyme A .

HY-CE01180

*3-Oxo-9-methyldecanoyl-CoA* 3-OXO-9-methyldecanoyl-coenzyme A	Biochemical Assay Reagents	Metabolic Disease
3-Oxo-9-methyldecanoyl-CoA (3-Oxo-9-methyldecanoyl-coenzyme A) is a derivative of coenzyme A .

HY-CE01146

*3-Oxo-15-methylhexadecanoyl-CoA* 3-OXO-15-methylhexadecanoyl-coenzyme A	Biochemical Assay Reagents	Metabolic Disease
3-Oxo-15-methylhexadecanoyl-CoA (3-Oxo-15-methylhexadecanoyl-coenzyme A) is a derivative of coenzyme A .

HY-CE01161

*3-Oxo-19-methyleicosanoyl-CoA* 3-OXO-19-methyleicosanoyl-coenzyme A	Biochemical Assay Reagents	Metabolic Disease
3-Oxo-19-methyleicosanoyl-CoA (3-Oxo-19-methyleicosanoyl-coenzyme A) is a derivative of coenzyme A .

HY-CE01174

*3-Oxo-5-methylhexanoyl-CoA* 3-OXO-5-methylhexanoyl-coenzyme A	Biochemical Assay Reagents	Metabolic Disease
3-Oxo-5-methylhexanoyl-CoA (3-Oxo-5-methylhexanoyl-coenzyme A) is a derivative of coenzyme A .

HY-CE01145

*3-Oxo-13-methyltetradecanoyl-CoA* 3-OXO-13-methyltetradecanoyl-coenzyme A	Biochemical Assay Reagents	Metabolic Disease
3-Oxo-13-methyltetradecanoyl-CoA (3-Oxo-13-methyltetradecanoyl-coenzyme A) is a derivative of coenzyme A .

HY-CE01163

*3-Oxo-21-methyldocosanoyl-CoA* 3-OXO-21-methyldocosanoyl-coenzyme A	Biochemical Assay Reagents	Metabolic Disease
3-Oxo-21-methyldocosanoyl-CoA (3-Oxo-21-methyldocosanoyl-coenzyme A) is a derivative of coenzyme A .

HY-CE01144

*3-Oxo-11-methyldodecanoyl-CoA* 3-OXO-11-methyldodecanoyl-coenzyme A	Biochemical Assay Reagents	Metabolic Disease
3-Oxo-11-methyldodecanoyl-CoA (3-Oxo-11-methyldodecanoyl-coenzyme A) is a derivative of coenzyme A .

HY-CE01170

*3-Oxo-25-methylhexacosanoyl-CoA* 3-OXO-25-methylhexacosanoyl-coenzyme A	Biochemical Assay Reagents	Metabolic Disease
3-Oxo-25-methylhexacosanoyl-CoA (3-Oxo-25-methylhexacosanoyl-coenzyme A) is a derivative of coenzyme A .

HY-134997

*4-Oxo* Docosahexaenoic Acid** 4-OXO DHA	PPAR	Cancer
4-oxo Docosahexaenoic acid (4-oxo DHA) is a putative metabolite of Docosahexaenoic acid (HY-B2167) with antiproliferative and PPARγ agonist activity. It inhibits the growth of several triple negative breast cancer cell lines (MCF-10F, trMCF, bsMCF, MDA-MB-231, and BT549) at 50-100 μM, however it increased proliferation of MCF-7 cells. 4-oxo DHA binds covalently to PPARγ and activates gene transcription in luciferase reporter assays and in dendritic cells with EC₅₀ values of approximately 8-16 μM.

HY-116752

*Dinor-12-oxo* phytodienoic acid** 2,3-Dinor-12-OXO-10,15(Z)-phytodienoic acid	Biochemical Assay Reagents	Metabolic Disease
Dinor-12-oxo phytodienoic acid (2,3-Dinor-12-oxo-10,15(Z)-phytodienoic acid) is an ester product.

HY-CE01173

*3-Oxo-4-methyl-pentanoyl-CoA* 3-OXO-4-methyl-pentanoyl-coenzyme A	Biochemical Assay Reagents	Metabolic Disease
3-Oxo-4-methyl-pentanoyl-CoA (3-Oxo-4-methyl-pentanoyl-coenzyme A) is a derivative of coenzyme A .

HY-CE01063

*3-Oxo-(2S)-Methylisocapryloyl-CoA* 3-OXO-(2S)-Methylisocapryloyl-coenzyme A	Biochemical Assay Reagents	Metabolic Disease
3-Oxo-(2S)-Methylisocapryloyl-CoA (3-Oxo-(2S)-Methylisocapryloyl-coenzyme A) is a derivative of coenzyme A .

HY-CE01177

*3-Oxo-6Z-dodecenoyl-CoA* 3-OXO-6Z-dodecenoyl-coenzyme A	Biochemical Assay Reagents	Metabolic Disease
3-Oxo-6Z-dodecenoyl-CoA (3-Oxo-6Z-dodecenoyl-coenzyme A) is a derivative of coenzyme A .

HY-CE01075

*3-Oxo-5,6-dehydrosuberyl-CoA* 3-OXO-5,6-dehydrosuberyl-coenzyme A	Biochemical Assay Reagents	Metabolic Disease
3-Oxo-5,6-dehydrosuberyl-CoA (3-Oxo-5,6-dehydrosuberyl-coenzyme A) is a derivative of coenzyme A .

HY-CE01181

*3-Oxo-9Z-hexadecenoyl-CoA* 3-OXO-9Z-hexadecenoyl-coenzyme A	Biochemical Assay Reagents	Metabolic Disease
3-Oxo-9Z-hexadecenoyl-CoA (3-Oxo-9Z-hexadecenoyl-coenzyme A) is a derivative of coenzyme A .

HY-CE01179

*3-Oxo-7Z-tetradecenoyl-CoA* 3-OXO-7Z-tetradecenoyl-coenzyme A	Biochemical Assay Reagents	Metabolic Disease
3-Oxo-7Z-tetradecenoyl-CoA (3-Oxo-7Z-tetradecenoyl-coenzyme A) is a derivative of coenzyme A .

HY-143813S

*2-Oxo* Prasugrel-d4 hydrochloride**	Isotope-Labeled Compounds	Others
2-Oxo Prasugrel-d₄ (hydrochloride) is the deuterium labeled 2-Oxo Prasugrel hydrochloride .

HY-143934S

*4-Oxo* cyclophosphamide-d8**	Isotope-Labeled Compounds	Others
4-Oxo cyclophosphamide-d₈ is the deuterium labeled 4-Oxo cyclophosphamide .

HY-CE01078

*3-Oxo-valproicacid-CoA* 3-OXO-valproic acid coenzyme A	Biochemical Assay Reagents	Metabolic Disease
3-Oxo-valproicacid-CoA (3-Oxo-valproic acid coenzyme A) is a derivative of coenzyme A .

HY-168015

*5-Oxo* leukotriene B4**	Drug Isomer	Infection
5-Oxo leukotriene B4 is a byproduct in the synthesis of 12-oxo LTB4 (HY-130497) with antiviral activity. 5-Oxo leukotriene B4 is promising for research of viral infections caused by human and animal enveloped RNA viruses .

HY-130497

*12-Oxo-leukotriene B4* 12-OXO-LTB4	Endogenous Metabolite	Inflammation/Immunology
12-Oxo-leukotriene B4 (12-Oxo-LTB4) is an intermediate in the lipoxygenase-catalyzed path of Arachidonic acid (HY-109590) metabolism. 12-Oxo-leukotriene B4 is crucial in Leukotriene B4 metabolism and is involved in inflammation reactions . 12-Oxo-leukotriene B4 stimulates calcium levels in human neutrophils with an EC₅₀ of 33 nM. 12-Oxo-leukotriene B4 induces migration of neutrophils with EC₅₀ of 170 nM .

HY-W742066

*7-Oxo* Cholesterol 3-Acetate-d7**	Isotope-Labeled Compounds	Others
7-Oxo Cholesterol 3-Acetate-d₇ is the deuterium labeled 7-Oxo Cholesterol 3-Acetate.

HY-CE01536

*5-Oxo-L-norleucine-CoA* 5-OXO-L-norleucine-coenzyme A	Biochemical Assay Reagents	Metabolic Disease
5-Oxo-L-norleucine-CoA (5-Oxo-L-norleucine-coenzyme A) is a coenzyme A derivative .

HY-118025R

*(±)-2-Oxo* clopidogrel (Standard)** (±)-SR-121683 (Standard)	Drug Metabolite Reference Standards	Others
(±)-2-Oxo clopidogrel (Standard) is the analytical standard of (±)-2-Oxo clopidogrel. This product is intended for research and analytical applications. (±)-2-Oxo clopidogrel is a metabolite of the antiplatelet agent Clopidogrel (HY-15283) .

Cat. No.	Product Name	Type

HY-W354821

4-Methylumbelliferyl Decanoate 4-MUD	Fluorescent Dye
4-Methyl-2-oxo-2H-1-benzopyran-7-yl decanoate is a fluorogenic substrate used to follow the hydrolytic activity of carboxylesterases .

HY-D1488

*Ethyl benzo[6,7]-4-oxo-4H-quinolizine-3-carboxlate*	Fluorescent Dye
Ethyl benzo[6,7]-4-oxo-4H-quinolizine-3-carboxlate (Compound 3) is a Mg ²⁺ selective fluorescent indicator .

HY-D0065

6,7-Dimethoxy-4-coumarinylacetic acid

2-(6,7-Dimethoxy-2-OXO-2H-chromen-4-yl)acetic acid

Fluorescent Dye

6,7-Dimethoxy-4-coumarinylacetic acid (2-(6,7-Dimethoxy-2-oxo-2H-chromen-4-yl)acetic acid) is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.

Cat. No.	Product Name	Type

HY-D0046

Coumarin-6-sulfonyl chloride 2-OXO-2H-chromene-6-sulfonyl chloride	Biochemical Assay Reagents
Coumarin-6-sulfonyl chloride is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-32959

N-Boc-2-pyrroleboronic acid

Biochemical Assay Reagents

N-Boc-2-pyrroleboronic acid is an organic synthesis intermediate used primarily in the synthesis of chiral pharmaceutical molecules and biologically active molecules. The boronic acid on the pyrrole ring can participate in Suzuki coupling reactions. The boronic acid can be oxidized to a hydroxyl group under the action of nitrogen oxides, and after tautomerization, it can be further transformed into 2-oxo-2,5-dihydro-1-pyrrolecarboxylic acid tert-butyl ester .

HY-W127393

N-Nonanoyl-L-homoserine lactone

Biochemical Assay Reagents

Quorum sensing is a regulatory system used by bacteria to control gene expression in response to increased cell density. This regulatory process manifests itself in a variety of phenotypes, including biofilm formation and virulence factor production. Coordinated gene expression is achieved through the production, release and detection of small diffusible signaling molecules called autoinducers. N-acylated homoserine lactones (AHLs) comprise a class of such autoinducers, each of which generally consists of a fatty acid coupled to a homoserine lactone (HSL). Modulation of bacterial quorum-sensing signaling systems to suppress pathogenesis represents a new approach to antimicrobial research for infectious diseases. AHLs differ in acyl length (C4-C18), C3 substitution (hydrogen, hydroxyl, or oxo group), and the presence or absence of one or more carbon-carbon double bonds in the fatty acid chain. These differences confer signaling specificity through the affinity of the LuxR family of transcriptional regulators. C9-HSL is a rare odd-numbered acyl carbon chain produced by wild-type Erwinia carotovora strain SCC 3193 grown in nutrient-rich Luria-Bertani broth (LB) medium.

HY-W015366

*(S)-3-Amino-2-oxo-azepane hydrochloride*	Biochemical Assay Reagents
(S)-3-Amino-2-oxo-azepane (hydrochloride) is a biochemical reagent that can be used as a biological material or organic compound for life science related research .

HY-W002765

2-Hydroxy-isonicotinic acid	Biochemical Assay Reagents
2-Oxo-1,2-dihydropyridine-4-carboxylic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W616806

*Sodium 6-oxo-3,6-dihydropurin-7-ide*	Biochemical Assay Reagents
Sodium 6-oxo-3,6-dihydropurin-7-ide, a purine derivative, is a potential free radical generator and could be used as an indicator of hypoxia.

HY-W272401

*4-Methyl-2-oxo-2H-chromene-6,7-diyl diacetate*	Biochemical Assay Reagents
4-Methyl-2-oxo-2H-chromene-6,7-diyl diacetate is a biochemical reagent.

HY-W650530

*Ethyl 8-chloro-4-oxo-4H-quinolizine-3-carboxlate*	Biochemical Assay Reagents
Ethyl 8-chloro-4-oxo-4H-quinolizine-3-carboxlate is a kind of biochemical reagent.

HY-W782081

*p-SCN-Bn-oxo-DO3A*	Biochemical Assay Reagents
p-SCN-Bn-oxo-DO3Ais a bifunctional chelator (Bifunctional Chelator; BFC) and a macrocyclic DOTA derivative used for tumor pre-targeting. p-SCN-Bn-oxo-DO3A can be used for conjugation of peptides and radionuclides.

HY-W782080

*p-NH2-Bn-oxo-DO3A*	Biochemical Assay Reagents
p-NH2-Bn-oxo-DO3Ais a bifunctional chelator (Bifunctional Chelator; BFC) and a macrocyclic DOTA derivative used for tumor pre-targeting. p-NH2-Bn-oxo-DO3A can be used for conjugation of peptides and radionuclides.

HY-W127486

*N-3-oxo-Hexadec-11Z-enoyl-L-homoserine lactone*	Biochemical Assay Reagents
N-3-oxo-hexadec-11Z-enoyl-L-Homoserine lactone is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-114773

N-Undecanoyl-L-homoserine lactone

Biochemical Assay Reagents

Quorum sensing is a regulatory system used by bacteria to control gene expression in response to increased cell density. This regulatory process manifests itself in a variety of phenotypes, including biofilm formation and virulence factor production. Coordinated gene expression is achieved through the production, release and detection of small diffusible signaling molecules called autoinducers. N-acylated homoserine lactones (AHLs) comprise a class of such autoinducers, each of which generally consists of a fatty acid coupled to a homoserine lactone (HSL). Modulation of bacterial quorum-sensing signaling systems to suppress pathogenesis represents a new approach to antimicrobial research for infectious diseases. AHLs differ in acyl length (C4-C18), C3 substitution (hydrogen, hydroxyl, or oxo group), and the presence or absence of one or more carbon-carbon double bonds in the fatty acid chain. These differences confer signaling specificity through the affinity of the LuxR family of transcriptional regulators. C11-HSL has a rare odd-numbered acyl carbon chain and may be a minor quorum-sensing signaling molecule in Pseudomonas aeruginosa strains.

HY-W127487

N-Octadecanoyl-L-homoserine lactone

Biochemical Assay Reagents

Quorum sensing is a regulatory system used by bacteria to control gene expression in response to increased cell density. This regulatory process manifests itself in a variety of phenotypes, including biofilm formation and virulence factor production. Coordinated gene expression is achieved through the production, release and detection of small diffusible signaling molecules called autoinducers. N-acylated homoserine lactones (AHLs) comprise a class of such autoinducers, each of which generally consists of a fatty acid coupled to a homoserine lactone (HSL). Modulation of bacterial quorum-sensing signaling systems to suppress pathogenesis represents a new approach to antimicrobial research for infectious diseases. AHLs differ in acyl length (C4-C18), C3 substitution (hydrogen, hydroxyl, or oxo group), and the presence or absence of one or more carbon-carbon double bonds in the fatty acid chain. These differences confer signaling specificity through the affinity of the LuxR family of transcriptional regulators. C18-HSL, one of four lipophilic long acyl side chain AHLs produced by the LuxI AHL synthase homolog SinI, is involved in quorum-sensing signaling in strains of Rhizobium meliloti (a nitrogen-fixing bacterial symbiont of the legume M. sativa) . C18-HSL and other hydrophobic AHLs tend to localize in the relatively lipophilic environment of bacterial cells and cannot diffuse freely across the cell membrane. Long-chain N-acyl homoserine lactones can be exported from cells by efflux pumps, or can be transported between communicating cells by extracellular outer membrane vesicles.

HY-W071148

*Ethyl 4-oxo-3H-phthalazin-1-ylacetate*	Biochemical Assay Reagents
Ethyl 4-oxo-3H-phthalazin-1-ylacetate is a biochemical reagent .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-113338

8-Hydroxyguanine 8-OXOguanine; 8-OXO-Gua	Natural Products Immune System Disorder Classification of Application Fields Disease markers Other Diseases Endocrine diseases Nervous System Disorder Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
8-Hydroxyguanine is a DNA damage product under oxidative stress, which is formed when hydroxyl radicals attack guanine in DNA. 8-Hydroxyguanine induces mutagenesis and leads to a transversion from G to T. 8-Hydroxyguanine is a marker of DNA oxidative damage .

HY-N7387

3-Oxocholic acid 3-Dehydrocholic acid	Classification of Application Fields Metabolic Disease Endogenous metabolite Disease Research Fields Steroids Source Classification	Endogenous Metabolite
3-Oxocholic acid is an oxo-bile acid metabolite and also a major degradation product from cholic by C. perfringens in the intestine. 3-Oxocholic acid is steroid acid found predominantly in bile of mammals .

HY-W011540

8-Hydroxy-2'-deoxyguanosine 5+ Cited Publications 8-OXO-2-deoxyguanosine	Structural Classification Natural Products Endogenous metabolite Source Classification	Endogenous Metabolite
8-Hydroxy-2'-deoxyguanosine is a critical biomarker of oxidative stress and carcinogenesis.

HY-N0501

*11-oxo-mogroside V* 1 Publications Verification	Triterpenes Classification of Application Fields Terpenoids Cucurbitaceae Metabolic Disease Siraitia grosvenorii (Swingle) C. Jeffrey ex Lu et Z. Y. Zhang Plants Disease Research Fields Sweeteners Source Classification Food Research	Reactive Oxygen Species (ROS)
11-oxo-mogroside V is a natural sweetener that exhibits strong antioxidant activity. It exhibits significant inhibitory effects on reactive oxygen species (O₂ ^-, H₂O₂ and OH) with EC₅₀* of 4.79, 16.52, and 146.17 μg/mL, respectively.

HY-N4226

*1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxylic acid* 1 Publications Verification	Structural Classification Microorganisms other families Classification of Application Fields Ketones, Aldehydes, Acids Plants Disease Research Fields Source Classification Cancer	AP-1 COX
1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxylic acid is an AP-1 inhibitor which can be found in Cordyceps bassiana. 1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxylic acid downregulates the expression of COX-2. 1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxylic acid can be used for the study of atopic dermatitis .

HY-W018512

7-Ketolithocholic acid 4 Publications Verification 3α-Hydroxy-7-OXO-5β-cholanic acid	Microorganisms Classification of Application Fields Metabolic Disease Endogenous metabolite Disease Research Fields Steroids Source Classification	Endogenous Metabolite
7-Ketolithocholic acid (3α-Hydroxy-7-oxo-5β-cholanic acid), a bile acid, can be absorbed and suppresses endogenous bile acid production and biliary cholesterol secretion .

HY-N2920

β-Amyrenonol 11-OXO-β-amyrin	Triterpenes Structural Classification Classification of Application Fields Terpenoids Myrtaceae Rhodomyrtus tomentosa Plants Pentacyclic Triterpenoids Inflammation/Immunology Disease Research Fields Source Classification	Cytochrome P450
β-Amyrenonol (11-Oxo-β-amyrin), an oleanolic-type triterpenoid in licorice roots, is a precursor of Glycyrrhetinic acid. β-Amyrenonol has anti-proliferative and anti-inflammatory activities, and β-Amyrenonol could function as the skeleton for the synthesis of many triterpenoids .

HY-N0829

Shionone 1 Publications Verification	Classification of Application Fields Terpenoids Diterpenoids Plants Compositae Sesbania vesicaria (Jacq.) Elliott Inflammation/Immunology Disease Research Fields	Others
Shionone is the major triterpenoid isolated from Aster tataricus, has anti-tussive, anti-inflammatory activities . Shionone possesses a unique six-membered tetracyclic skeleton and 3-oxo-4-monomethyl structure .

HY-112817

*8-Oxo-dGTP* 8-OXO-Deoxyguanosine triphosphate	Microorganisms Source Classification	Apoptosis
8-Oxo-dGTP (8-Oxo-Deoxyguanosine triphosphate) is an oxidized guanine nucleotide formed by ROS-mediated oxidative modification of dGTP, and it also serves as a key substrate for 8-oxo-dGTP pyrophosphohydrolases (such as hMTH1 and E. coli MutT). 8-Oxo-dGTP acts as a DNA mutagen, inserts into nascent DNA and pairs with adenine and cytosine, inducing A:T to C:G transversion mutations. Furthermore, 8-Oxo-dGTP causes oxidative DNA base modification, strand breakage and S-phase arrest, and ultimately triggers AIF-mediated apoptosis and promotes spontaneous carcinogenesis in mth1-deficient mice. Accumulation of 8-Oxo-dGTP in cells induces genomic instability, but it exhibits a tumor-suppressive effect that reduces tumor incidence in mouse models instead. 8-Oxo-dGTP is widely used in studies related to spontaneous carcinogenesis, Parkinson's disease, Alzheimer's disease, heart failure and tumor mechanisms .

HY-N9945

*3-Oxo-7-hydroxychol-4-enoic acid*	Classification of Application Fields Endogenous metabolite Disease Research Fields Inflammation/Immunology Steroids Source Classification	Endogenous Metabolite
3-Oxo-7-hydroxychol-4-enoic acid is an endogenous metabolite. 3-Oxo-7-hydroxychol-4-enoic acid may be an important indicator of a poor prognosis in hepatobiliary disease .

HY-118828A

*(9S,13R)-12-Oxo* phytodienoic acid** (9S,13R)-12-OPDA	Structural Classification Ketones, Aldehydes, Acids Solanum tuberosum L. Solanaceae Plants Source Classification	Lipoxygenase
9S,13R)-12-Oxo phytodienoic acid is the isomerization of 12-oxo PDA (HY-118828). (9S,13R)-12-Oxo phytodienoic acid is a lipoxygenase metabolite in the leaves of green plants .

HY-W391635

*3-Oxo* deoxycholic acid**	Microorganisms Source Classification	Drug Metabolite
3-oxo Deoxycholic acid is a secondary bile acid and a metabolite of Deoxycholic acid (HY-N0593) in C. perfringens .

HY-N9944

*3-Oxo-4,6-choladien-24-oic acid*	Classification of Application Fields Metabolic Disease Endogenous metabolite Disease Research Fields Steroids Source Classification	Endogenous Metabolite
3-Oxo-4,6-choladien-24-oic acid is an endogenous metabolite. 3-Oxo-4,6-choladien-24-oic acid exsists in the urine of patients with hepatobiliary disease .

HY-131376

*13-Oxo-ODE*	Ketones, Aldehydes, Acids Plants Compositae Sindora sumatrana Miq. Source Classification	PPAR
13-Oxo-ODE is an octadecadienoic acid, that can be isolated from the leaves of Artemisia argyi .

HY-W018512R

7-Ketolithocholic acid (Standard) 3α-Hydroxy-7-OXO-5β-cholanic acid (Standard)	Structural Classification Microorganisms Endogenous metabolite Steroids Source Classification	Reference Standards Endogenous Metabolite
7-Ketolithocholic acid (Standard) is the analytical standard of 7-Ketolithocholic acid. This product is intended for research and analytical applications. 7-Ketolithocholic acid (3α-Hydroxy-7-oxo-5β-cholanic acid), a bile acid, can be absorbed and suppresses endogenous bile acid production and biliary cholesterol secretion .

HY-N12851

4-OHE (E)-4-OXO-2-hexenal	Structural Classification Animals Ketones, Aldehydes, Acids Source Classification	Bacterial Apoptosis
4-OHE ((E)-4-Oxo-2-hexenal) is a mutagen formed by omega-3 lipid peroxidation. 4-OHE reacts with deoxyguanosine, deoxycytidine and 5-methyldeoxycytidine to form covalent adducts. 4-OHE induces apoptosis and exhibits genotoxicity. 4-OHE inhibits the growth of Gram-positive and Gram-negative bacteria, which correlates with its electrophilic reactivity towards nucleophilic biomolecules. 4-OHE is a chemical defense component of Dolycoris baccarum (sloe bug), and acts as a deterrent and toxin against insect predators .

HY-134560

N-(3-Oxodecanoyl)-L-homoserine lactone 3-OXO-C10-HSL	Microorganisms Ketones, Aldehydes, Acids Source Classification	Bacterial
N-(3-Oxodecanoyl)-L-homoserine lactone (3-Oxo-C10-HSL) is a bacterial quorum sensing signal autoinducer molecule .

HY-N9483

7-Keto-DHEA 7-OXO-DHEA; 7-Ketodehydroepiandrosterone; 7-OXOdehydroepiandrosterone	Endogenous metabolite Steroids Source Classification	GABA Receptor
7-Keto-DHEA binds to GABA Receptor, and reduces the ethanol intake in rats. 7-Keto-DHEA exhibits potential in investigation of alcohol dependence disorders .

HY-133683

N-(3-Oxotetradecanoyl)-DL-homoserine lactone 3-OXO-C14-AHL	Natural Products Microorganisms Classification of Application Fields Metabolic Disease Disease Research Fields Source Classification	Bacterial
N-(3-Oxotetradecanoyl)-DL-homoserine lactone, a member of N-Acyl homoserine lactone (AHL) from gram-negative bacteria, is a quorum sensing (QS) signaling molecule .

HY-N9768

*(10E,12E)-9-Oxo-10,12-octadecadienoic acid* 9-OXO-ODA	Microorganisms Ketones, Aldehydes, Acids Source Classification	Fungal PPAR
(10E,12E)-9-Oxo-10,12-octadecadienoic acid (9-oxo-ODA) is a PPARα agonist that can be isolated from the basidiomycete Gomphus floccosus. (10E,12E)-9-Oxo-10,12-octadecadienoic acid enhances fatty acid oxidation through PPARα activation, thereby inhibiting triglyceride accumulation. (10E,12E)-9-Oxo-10,12-octadecadienoic acid also has antifungal (Fungal) activity .

HY-113457

*11-Oxo* etiocholanolone** 11-Ketoetiocholanolone	Endogenous metabolite Steroids Source Classification	Endogenous Metabolite Biochemical Assay Reagents
11-Oxo etiocholanolone (11-Ketoetiocholanolone) is a steroid. 11-Oxo etiocholanolone is a key indicator for detecting cortisol metabolites in feces and urine. 11-Oxo etiocholanolone has the potential to be a pheromone .

HY-N16603

*16-Oxo-3-episerratenediol*	Lycopodiaceae Triterpenes Structural Classification Terpenoids Lycopodium japonicum Thunb. ex Murray Plants Source Classification	Others
16-Oxo-3-episerratenediol is a type of triterpenoid compound that can be found in the Lycopodium clavatum .

HY-N5097

*13-Oxo-9E,11E-octadecadienoic acid*	Structural Classification other families Classification of Application Fields Metabolic Disease Plants Disease Research Fields Lipid Source Classification	PPAR
13-Oxo-9E,11E-octadecadienoic acid, an isomer of 9-oxo-ODA, is a potent PPARα activator derived from tomato juice. 13-Oxo-9E,11E-octadecadienoic acid decreases plasma and hepatic triglyceride in obese diabetic mice .

HY-N10854

*Lanosta-7,9(11),23,25(27)-tetraen-26-oic acid, 23,27-epoxy-3-oxo-*	Triterpenes Pinaceae Terpenoids Pseudolarix amabilis (J. Nelson) Rehder Plants Source Classification	Others
Lanosta-7,9(11),23,25(27)-tetraen-26-oic acid, 23,27-epoxy-3-oxo- is a lanosterane type compound. Lanosta-7,9(11),23,25(27)-tetraen-26-oic acid, 23,27-epoxy-3-oxo- can be isolated from Tu-Jin-Pi (the root bark of Pseudolarix kaempferi) .

HY-N4155

*2α,19α-Dihydroxy-3-oxo-urs-12-en-28-oic acid*	Rosaceae Rosa cymosa (L.) Tratt. Plants	EBV HIV Protease HSV
2α,19α-Dihydroxy-3-oxo-urs-12-en-28-oic acid, a natural ursane-type triterpene, is a potent inhibitor of HIV protease (HIV Protease). 2α,19α-Dihydroxy-3-oxo-urs-12-en-28-oic acid is also an inhibitor of the activation of Epstein-Barr virus early antigen (EBV-EA). 2α,19α-Dihydroxy-3-oxo-urs-12-en-28-oic acid displays an inhibitory activity against nitric oxide production in Lipopolysaccharide (Lipopolysaccharides)-activated RAW 264.7 cells .

HY-N2277

*3β,7β,15β-Trihydroxy-11-oxo-lanosta-8-en-24→20 lactone*	Triterpenes Structural Classification Tetracyclic Triterpenoids Classification of Application Fields Terpenoids Polyporaceae Ganoderma lucidum (Leyss. Ex Fr.) Karst. Plants Inflammation/Immunology Disease Research Fields Source Classification	Bacterial
3β,7β,15β-Trihydroxy-11-oxo-lanosta-8-en-24→20 lactone is a natural compound that could be isolated from G. lucidum with antimycobacterial activity.

HY-W011540R

8-Hydroxy-2'-deoxyguanosine (Standard) 8-OXO-2-deoxyguanosine (Standard)	Structural Classification Natural Products Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite
8-Hydroxy-2'-deoxyguanosine is a critical biomarker of oxidative stress and carcinogenesis.

HY-N4226R

*1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxylic acid (Standard)*	Microorganisms other families Ketones, Aldehydes, Acids Plants Source Classification	Reference Standards AP-1 COX
1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxylic acid (Standard) is the analytical standard of 1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxylic acid (HY-N4226). This product is intended for research and analytical applications. 1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxylic acid is an AP-1 inhibitor which can be found in Cordyceps bassiana. 1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxylic acid downregulates the expression of COX-2. 1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxylic acid can be used for the study of atopic dermatitis.

HY-131597

*8-Oxo-GTP* 8-Hydroxyguanosine triphosphate	Source Classification	Reactive Oxygen Species (ROS)
8-Oxo-GTP is an oxidized guanine nucleotide, produced by reactive oxygen species (ROS). 8-Oxo-GTP serves as a substrate for MutT protein, GTP cyclohydrolase II, Mycobacterium tuberculosis MutT1, and Mycobacterium tuberculosis Rv1700, which hydrolyze it to corresponding nucleoside monophosphates or diphosphates. 8-Oxo-GTP causes detrimental effects including mutations and mistranslation when incorporated into nucleic acids. 8-Oxo-GTP can be used for the research of cancer and tuberculosis .

HY-N2802

Euptox A 9-OXO-10,11-dehydroageraphorone	Pongamia pinnata (L.) Pierre Terpenoids Sesquiterpenes Plants Compositae Source Classification	Apoptosis Caspase Parasite
Euptox A (9-Oxo-10, 11-dehydroageraphorone), a cadenine sesquiterpene, is the main toxin that can be isolated from Eupatorium adenophorum. Euptox A induces apoptosis by improving the gene expression level of apoptotic proteases such as caspase-10 in HeLa cells .

HY-N11163

*(Z)-(1R,3R,4R,4aS,8R,8aR)-3,4,8,8a-Tetramethyl-7-oxo-4-(2-(5-oxo-2,5-dihydrofuran-3-yl)ethyl)decahydronaphthalen-1-yl 2-methylbut-2-enoate*	Terpenoids Diterpenoids Plants Compositae Glycyrrhiza lepidota Pursh Source Classification	Others
(Z)-(1R,3R,4R,4aS,8R,8aR)-3,4,8,8a-Tetramethyl-7-oxo-4-(2-(5-oxo-2,5-dihydrofuran-3-yl)ethyl)decahydronaphthalen-1-yl 2-methylbut-2-enoate (compound 7a) is a clerodane diterpene .

HY-W552832

10-Oxooctadecanoic acid	Structural Classification Animals Ketones, Aldehydes, Acids Lipid Source Classification	Endogenous Metabolite
10-Oxooctadecanoic acid is an oxo fatty acid that can be isolated from mature adipocere in human remains that have been deceased for 6 months. 10-Oxooctadecanoic acid, together with monohydroxy fatty acids, promotes the enhancement and stabilization of adipocere formation .

HY-113801

N-(3-Oxooctanoyl)-DL-homoserine lactone (Rac)-3-OXO-C8-HSL	Natural Products Microorganisms Classification of Application Fields Metabolic Disease Disease Research Fields Source Classification	Endogenous Metabolite
N-(3-Oxooctanoyl)-DL-homoserine lacton is a member of N-Acyl homoserine lactone (AHL) from gram-negative bacteria, with stereochemistry-dependent growth regulatory activity for roots .

HY-N9011

*16-Oxo-11-anhydroalisol A*	Triterpenes Alisma orinentale (Samuel.) Juz. Plants Alismataceae Source Classification	Others
16-Oxo-11-anhydroalisol A is a triterpenoid from Alisma orientale .

HY-N9944R

*3-Oxo-4,6-choladien-24-oic acid (Standard)*	Endogenous metabolite Steroids Source Classification	Reference Standards Endogenous Metabolite
3-Oxo-4,6-choladien-24-oic acid (Standard) is the analytical standard of 3-Oxo-4,6-choladien-24-oic acid. This product is intended for research and analytical applications. 3-Oxo-4,6-choladien-24-oic acid is an endogenous metabolite. 3-Oxo-4,6-choladien-24-oic acid exsists in the urine of patients with hepatobiliary disease[1].

HY-N10930

*7-Oxo-ganoderic acid Z*	Triterpenes Commiphora myrrha (Nees) Engl. Terpenoids Plants Burseraceae Source Classification	Bacterial
7-Oxo-ganoderic acid Z, a terpenoid, is a nature product that could be isolated from Resina Commiphora. 7-Oxo-ganoderic acid Z has Anti-Mycobacterium tuberculosis activity .

HY-N1639

*1-Decarboxy-3-oxo-ceanothic acid* DOCA	Triterpenes Animals Terpenoids Source Classification	Apoptosis DNA/RNA Synthesis
1-Decarboxy-3-oxo-ceanothic acid is an anticancer agent. 1-Decarboxy-3-oxo-ceanothic acid inhibits DNA synthesis. 1-Decarboxy-3-oxo-ceanothic acid induces Apoptosis .

HY-W736195

*5-Hydroxy-4-oxo-L-norvaline*	Microorganisms Antifungal Antibiotics Disease Research Source Classification	Antibiotic Bacterial
5-Hydroxy-4-oxo-L-norvaline is an antifungal antibiotic. 5-Hydroxy-4-oxo-L-norvaline can inhibit protein biosynthesis .

HY-N10440

*3-Oxo-hop-22(29)-ene*	Cnidoscolus spinosus Lundell Triterpenes Terpenoids Euphorbiaceae Plants Source Classification	Glycosidase
3-Oxo-hop-22(29)-ene is a yeast α-glucosidase inhibitor. 3-Oxo-hop-22(29)-ene shows a moderate effect on the viability of T. cruzi and L. mexicana. 3-Oxo-hop-22(29)-ene shows marginal activity of anti-inflammatory .

HY-N0501R

*11-oxo-mogroside V (Standard)*	Triterpenes Structural Classification Terpenoids Cucurbitaceae Siraitia grosvenorii (Swingle) C. Jeffrey ex Lu et Z. Y. Zhang Plants Source Classification	Reference Standards Reactive Oxygen Species (ROS)
11-oxo-mogroside V (Standard) is the analytical standard of 11-oxo-mogroside V. This product is intended for research and analytical applications. 11-oxo-mogroside V is a natural sweetener that exhibits strong antioxidant activity. It exhibits significant inhibitory effects on reactive oxygen species (O2-, H2O2 and OH) with EC₅₀* of 4.79, 16.52, and 146.17 μg/mL, respectively.

HY-N13080

*3-Oxo-bufalin*	Microorganisms Steroids Source Classification	Others
3-Oxo-bufalin is an active compound that can be isolated from cultured toad liver tissue. 3-Oxo-bufalin can be produced through a metabolic pathway, and it is a metabolite of Bufalin (HY-N0877) catalyzed by the stereoselective 3β-dehydrogenase. Bufalin is a Na+/K+-ATPase inhibitor and has anti-tumor activity .

HY-N10601

*11-Oxo-α-amyrin* Neoilexonol	Triterpenes Erythrophleum fordii Oliv. Terpenoids Labiatae Plants	Others
11-Oxo-α-amyrin (Neoilexonol) is a triterpenoid that can be isolated from Leonurus japonicus (Lamiaceae) .

HY-N7164

*3-Oxo-24,25,26,27-tetranortirucall-7-ene-23(21)-lactone*	Triterpenes Dysoxylum lenticellatum C. Y. Wu ex H. Li Terpenoids Plants Meliaceae Source Classification	Others
3-Oxo-24,25,26,27-tetranortirucall-7-ene-23(21)-lactone is a tetranortirucallane-type triterpenoid that can be isolated from Dysoxylum lenticellatum. 3-Oxo-24,25,26,27-tetranortirucall-7-ene-23(21)-lactone has vasodilative effect with diastolic degree of 43.5% at 10 μg/mL .

HY-N9290

*ent-6,9-Dihydroxy-15-oxo-16-kauren-19-oic acid*	Terpenoids Pteridaceae Diterpenoids Pteris semipinnata L. Sp. Plants Source Classification	Others
ent-6,9-Dihydroxy-15-oxo-16-kauren-19-oic acid is a Diterpenoids product that can be isolated from the herbs of Pteris semipinnata .

HY-W778547

*7-epi-10-Oxo-10-deacetyl baccatin III* 10-Dehydrobaccatin V	Terpenoids Taxaceae Diterpenoids Plants Taxus baccata L. Source Classification	Drug Intermediate
7-epi-10-Oxo-10-deacetyl baccatin III (10-Dehydrobaccatin V) can be isolated from the degradation impurities in Docetaxel (HY-B0011) .

HY-N10046

ent-17-Hydroxykauran-3-one ent-Kaurane-3-OXO-17β-ol	Euphorbia fischeriana Steud. Terpenoids Diterpenoids Euphorbiaceae Plants Source Classification	Others
ent-17-Hydroxykauran-3-one (ent-Kaurane-3-oxo-17β-ol; compound 7) is a kaurane-type diterpenoid that can be found in the roots of Euphorbia fischeriana .

HY-N13594

*(6R,9R)-3-Oxo-α-ionol glucoside*	Terpenoids Sesquiterpenes Rosaceae Plants Rosa rugosa Thunb. Source Classification	Others
(6R,9R)-3-Oxo-α-ionol glucoside is a natural product .

HY-N9025

*ent-6,9-Dihydroxy-15-oxo-16-kauren-19-oic acid beta-D-glucopyranosyl ester*	Terpenoids Pteridaceae Diterpenoids Pteris semipinnata L. Sp. Plants Source Classification	Others
ent-6,9-Dihydroxy-15-oxo-16-kauren-19-oic acid beta-D-glucopyranosyl ester is a Diterpenoids product that can be isolated from the herbs of Pteris semipinnata .

HY-N4162

*3-Oxo-21α-methoxy-24,25,26,27-tetranortirucall-7-ene-23(21)-lactone*	Triterpenes Classification of Application Fields Terpenoids Plants Disease Research Fields Meliaceae Aphanamixis polystachya (Wall.) R. N. Parker Cancer Source Classification	Others
3-Oxo-21α-methoxy-24,25,26,27-tetranortirucall-7-ene-23(21)-lactone is a cytotoxic tirucallane C26 triterpenoid isolated from the stem barks of Aphanamixis grandifolia .

HY-N9871

*(6R,9S)-3-Oxo-α-ionol β-D-glucopyranoside*	Terpenoids Sesquiterpenes Euphorbiaceae Plants Macaranga tanarius (L.) Muell. Arg. Source Classification	Others
(6R,9S)-3-Oxo-α-ionol β-D-glucopyranoside is a natural product .

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P71482

	MutT Protein, E.coli (His-SUMO) mutT; b0099; JW0097; 8-OXO-dGTP diphosphatase; 8-OXO-dGTPase; EC 3.6.1.55; 7,8-dihydro-8-OXOguanine-triphosphatase; Mutator protein MutT; dGTP pyrophosphohydrolase	E.coli	E. coli
	The MutT protein maintains the genome by hydrolyzing 8-oxo-deoxyguanosine triphosphate (8-oxo-dGTP) and 8-oxo-guanosine triphosphate (8-oxo-GTP) to their corresponding monophosphates. Integrity plays a key role. This prevents misincorporation of 8-oxoGua into DNA and RNA, ensuring the fidelity of the nucleotide library. MutT Protein, E.coli (His-SUMO) is the recombinant E. coli-derived MutT protein, expressed by E. coli , with N-His, N-SUMO labeled tag.

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Cat. No.	Product Name	Chemical Structure

HY-W767767

*2-Oxo-3-hydroxy-LSD-d10*
2-Oxo-3-hydroxy-LSD-d₁₀ is the deuterium labeled 2-Oxo-3-hydroxy-LSD (HY-137386). 2-Oxo-3-hydroxy-LSD is a metabolite of Lysergic acid diethylamide .

HY-138616S3

dGTP-13C10 dilithium
dGTP- ¹³C₁₀ (2'-Deoxyguanosine-5'-triphosphate- ¹³C₁₀) dilithium is ¹³C-labeled dGTP (HY-138616). dGTP (2'-Deoxyguanosine-5'-triphosphate), a guanosine nucleotide, can be used in deoxyribonucleic acid synthesis. Guanosine nucleotides (GDP, GTP, dGDP, and dGTP) are highly susceptible to oxidative damage to 8-oxo-GDP (8-O-GDP), 8-O-dGTP, 8-O-GTP, and 8-O-dGTP.

HY-113457S

*11-Oxo* etiocholanolone-d5**
11-Oxo etiocholanolone-d₅ (11-Ketoetiocholanolone-d₅) is the deuterium labeled 11-Oxo etiocholanolone (HY-113457). 11-Oxo etiocholanolone (11-Ketoetiocholanolone) is a steroid. 11-Oxo etiocholanolone is a key indicator for detecting cortisol metabolites in feces and urine. 11-Oxo etiocholanolone has the potential to be a pheromone .

HY-118828AS

*(9S,13R)-12-Oxo* phytodienoic acid-d5**
(9S,13R)-12-OPDA-d₅ ((9S,13R)-12-OPDA-d₅) is an isotopic label of (9S,13R)-12-oxyphytodienoic acid. (9S,13R)-12-Oxophytodienoic acid is an isomer of 12-oxoPDA (HY-118828). (9S,13R)-12-Oxo phytodienoic Acid is a lipoxygenase metabolite in green plant leaves .

HY-129242S

Tempone-15N,d16
Tempone- ¹⁵N,d₁₆ is the deuterium and ¹⁵N labeled Tempone .

HY-138616S4

dGTP-13C10,15N5 dilithium

dGTP- ¹³C₁₀, ¹⁵N₅ (2'-Deoxyguanosine-5'-triphosphate- ¹³C₁₀, ¹⁵N₅) dilithium is ¹³C and ¹⁵N-labeled dGTP (HY-138616). dGTP (2'-Deoxyguanosine-5'-triphosphate), a guanosine nucleotide, can be used in deoxyribonucleic acid synthesis. Guanosine nucleotides (GDP, GTP, dGDP, and dGTP) are highly susceptible to oxidative damage to 8-oxo-GDP (8-O-GDP), 8-O-dGTP, 8-O-GTP, and 8-O-dGTP.

HY-W778270

*2-Oxo* clopidogrel-13C,d3 hydrochloride**
2-Oxo clopidogrel- ¹³C,d₃ hydrochloride is the deuterium and ¹³C-labeled (±)-2-Oxo clopidogrel hydrochloride (HY-W585947).

HY-W654395

Methyl jasmonate-d5 (mixture of diastereomers)
Methyl jasmonate-d₅ (mixture of diastereomers) is deuterium labeled Methyl (Z)-2-(3-oxo-2-(pent-2-en-1-yl)cyclopentyl)acetate .

HY-143813S

*2-Oxo* Prasugrel-d4 hydrochloride**
2-Oxo Prasugrel-d₄ (hydrochloride) is the deuterium labeled 2-Oxo Prasugrel hydrochloride .

HY-143934S

*4-Oxo* cyclophosphamide-d8**
4-Oxo cyclophosphamide-d₈ is the deuterium labeled 4-Oxo cyclophosphamide .

HY-W742066

*7-Oxo* Cholesterol 3-Acetate-d7**
7-Oxo Cholesterol 3-Acetate-d₇ is the deuterium labeled 7-Oxo Cholesterol 3-Acetate.

HY-116752S

*Dinor-12-oxo* phytodienoic acid-d5**
Dinor-12-oxo phytodienoic acid-d₅ is the deuterium labeled Dinor-12-oxo phytodienoic acid .

HY-W014608S

*Ethyl 2-oxo-4-phenylbutanoate-d5*
Ethyl 2-oxo-4-phenylbutanoate-d₅ is the deuterium labeled Ethyl 2-oxo-4-phenylbutanoate .

HY-131376S

*13-Oxo-ODE-d3*
13-Oxo-ODE-d₃ is deuterated labeled 13-Oxo-ODE (HY-131376) 13-Oxo-ODE is an octadecadienoic acid, that can be isolated from the leaves of Artemisia argyi .

HY-17419S

*2’-Oxo* Ifosfamide-d4**
2’-Oxo Ifosfamide-d₄ is the deuterium labeled Ifosfamide. Ifosfamide is an alkylating chemotherapeutic agent with activity against a wide range of tumors .

HY-W704547

*4-Oxo-4-(pyridin-3-yl)butanoic acid-d4*
4-Oxo-4-(pyridin-3-yl)butanoic acid-d₄ is the deuterium labeled 4-Oxo-4-(pyridin-3-yl)butanoic acid (HY-W172380).

HY-W742556

*1-Oxo* Colterol-d9**
1-Oxo Colterol-d₉ is the deuterium labeled 2-(Tert-butylamino)-1-(3,4-dihydroxyphenyl)ethan-1-one (HY-W704235).

HY-114524S

*(E)-4-Oxo-2-nonenal-d3*
(E)-4-Oxo-2-nonenal-d₃ is the deuterium labeled (E)-4-Oxo-2-nonenal .

HY-W168915S

*1-(3-Fluorophenyl)-6-oxo-1,6-dihydropyridine-3-carboxylic acid-d3*
1-(3-Fluorophenyl)-6-oxo-1,6-dihydropyridine-3-carboxylic acid-d₃ is deuterium labeled 1-(3-Fluorophenyl)-6-oxo-1,6-dihydropyridine-3-carboxylic acid.

HY-W020671S

*N-[3-[3-(Dimethylamino)-1-oxo-2-propenyl]phenyl]-N-ethylacetamide-d3*
N-[3-[3-(Dimethylamino)-1-oxo-2-propenyl]phenyl]-N-ethylacetamide-d₃ is the deuterium labeled N-[3-[3-(Dimethylamino)-1-oxo-2-propenyl]phenyl]-N-ethylacetamide .

HY-W714570

o-Tolylglyoxylic Acid Methyl Ester-d7
o-Tolylglyoxylic Acid Methyl Ester-d₇ (Methyl 2-oxo-2-(o-tolyl)acetate-d₇) is the deuterium labeled Methyl 2-oxo-2-(o-tolyl)acetate (HY-W278295).

HY-109583S

4-Oxofenretinide-d4
4-Oxofenretinide-d₄ (4-Oxo-4-HPR-d₄) is deuterium labeled 4-Oxofenretinide. 4-Oxofenretinide (4-Oxo-4-HPR) is a metabolite of Fenretinide (HY-15373). 4-Oxofenretinide induces cell growth inhibition in ovarian, breast, and neuroblastoma tumor cell lines. 4-Oxofenretinide causes a marked accumulation of cells in G2-M. 4-Oxofenretinide induces cancer cell apoptosis through caspase-9 .

HY-W005294S

*Methyl 2-(2-(((benzyloxy)carbonyl)amino)propan-2-yl)-5-hydroxy-1-methyl-6-oxo-1,6-dihydropyrimidine-4-carboxylate-d3*
Methyl 2-(2-(((benzyloxy)carbonyl)amino)propan-2-yl)-5-hydroxy-1-methyl-6-oxo-1,6-dihydropyrimidine-4-carboxylate-d₃ is the deuterium labeled Methyl 2-(2-(((benzyloxy)carbonyl)amino)propan-2-yl)-5-hydroxy-1-methyl-6-oxo-1,6-dihydropyrimidine-4-carboxylate .

HY-W285163S

*1-Cyclopropyl-6-fluoro-7-(4-formylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid-d8*
1-Cyclopropyl-6-fluoro-7-(4-formylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid-d₈ is deuterated labeled 1-Cyclopropyl-6-fluoro-7-(4-formylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid.

HY-W140284S

*6-(5-Chloropyridin-2-yl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-yl piperazine-1-carboxylate-d8 hydrochloride*
6-(5-Chloropyridin-2-yl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-yl piperazine-1-carboxylate-d₈ (hydrochloride) is the deuterium labeled 6-(5-Chloropyridin-2-yl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-yl piperazine-1-carboxylate hydrochloride .

HY-146873S

*D-myo-Inositol, 1-[(2R)-3-[(1-oxoheptadecyl)oxy]-2-[[(9Z)-1-oxo-9-tetradecen-1-yl]oxy]propyl hydrogen phosphate], ammonium salt (1:1)*
D-myo-Inositol, 1-[(2R)-3-[(1-oxoheptadecyl)oxy]-2-[[(9Z)-1-oxo-9-tetradecen-1-yl]oxy]propyl hydrogen phosphate]-d₅, ammonium salt (1:1) is an isotopically labeled compound.

HY-146874S

*D-myo-Inositol, 1-[(2R)-3-[(1-oxoheptadecyl)oxy]-2-[[(9Z)-1-oxo-9-hexadecen-1-yl]oxy]propyl hydrogen phosphate], ammonium salt (1:1)*
D-myo-Inositol, 1-[(2R)-3-[(1-oxoheptadecyl)oxy]-2-[[(9Z)-1-oxo-9-hexadecen-1-yl]oxy]propyl hydrogen phosphate]-d₅, ammonium salt (1:1) is an isotopically labeled compound.

HY-146708S

*((2R,3S,4R,5R)-5-(2-Amino-6-oxo-3,6-dihydro-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl phosphate-15N4 sodium*
((2R,3S,4R,5R)-5-(2-Amino-6-oxo-3,6-dihydro-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl phosphate- ¹⁵N₄ (sodium) is a ¹⁵N-labeled ((2R,3S,4R,5R)-5-(2-Amino-6-oxo-3,6-dihydro-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl phosphate (so

HY-W756467

Antibacterial agent 265-13C,d3

Antibacterial agent 265- ¹³C,d₃ (1-Cyclopropyl-6,7-difluoro-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic Acid- ¹³C,d₃) is the deuterium labeled and ¹³C-labeled Antibacterial agent 265 (HY-W018629). Antibacterial agent 265 (Compound 2) is an antibacterial agent. Antibacterial agent 265 shows antibacterial activity against Staphylococcus Aureus, Micrococcus Luteus, Bacillus subtilis, gram-negative Escherichia coli, Pseudomonas aeruginosa and Flavobacterium devorans .

HY-W747973

N2,9-Diacetylguanine-13C2,15N
N2,9-Diacetylguanine- ¹³C₂, ¹⁵N (N-(9-Acetyl-6,9-dihydro-6-oxo-1H-purin-2-yl)acetamide- ¹³C₂, ¹⁵N) is the ¹³C- and ¹⁵N-labeled N2,N9-Diacetylguanine (HY-41619).

HY-W743770

O-Desethyl Azilsartan-d4
O-Desethyl Azilsartan-d₄ is the deuterium labeled 2-Oxo-3-((2'-(5-oxo-2,5-Dihydro-1,2,4-oxadiazol-3-yl)-[1,1'-biphenyl]-4-yl)methyl)-2,3-dihydro-1H-benzo[d]imidazole-4-carboxylic acid (HY-W612559).

HY-W011560S

3-Methylflavone-8-carboxylic acid-d5
3-Methylflavone-8-carboxylic acid-d₅ is the deuterium labeled 3-Methyl-4-oxo-2-phenyl-4H-chromene-8-carboxylic acid .

HY-143687S

3-Cyano Gimeracil methyl ether-13C3
3-Cyano Gimeracil methyl ether- ¹³C₃ is the ¹³C-labeled 5-Chloro-4-methoxy-2-oxo-1,2-dihydropyridine-3-carbonitrile (HY-W050667).

HY-W751415

Diethyl cromoglycate-d5
Diethyl cromoglycate-d₅ (Diethylchromoglycate-d₅) is the deuterium labeled Diethyl 5,5'-((2-hydroxypropane-1,3-diyl)bis(oxy))bis(4-oxo-4H-chromene-2-carboxylate) (HY-W099125).

HY-129242S1

Tempone-d16
Tempone-d₁₆ is the deuterium labeled Tempone .

HY-W741425

21-O-Acetyl dexamethasone 9,11-epoxide-d5
21-O-Acetyl dexamethasone 9,11-epoxide-d₅ is the deuterium labeled 2-((4aS,4bS,5aS,6aS,7R,8R,9aS,9bS)-7-Hydroxy-4a,6a,8-trimethyl-2-oxo-2,4a,5a,6,6a,7,8,9,9a,9b,10,11-dodecahydrocyclopenta[1,2]phenanthro[4,4a-b]oxiren-7-yl)-2-oxoethyl acetate (Dexamethasone Acetate Impurity) (HY-Z8003).

HY-W653916

8-Hydroxy-2'-deoxyguanosine-13C,15N2
8-Hydroxy-2'-deoxyguanosine- ¹³C, ¹⁵N₂ is ¹³C and ¹⁵N labeled 8-Hydroxy-2'-deoxyguanosine. 8-Hydroxy-2'-deoxyguanosine is a critical biomarker of oxidative stress and carcinogenesis .

HY-138616S1

dGTP-d14 dilithium
dGTP-d₁₄ (2'-Deoxyguanosine-5'-triphosphate-d₁₄) dilithium is deuterium labeled dGTP (HY-138616). dGTP (2'-Deoxyguanosine-5'-triphosphate), a guanosine nucleotide, can be used in deoxyribonucleic acid synthesis. Guanosine nucleotides (GDP, GTP, dGDP, and dGTP) are highly susceptible to oxidative damage to 8-oxo-GDP (8-O-GDP), 8-O-dGTP, 8-O-GTP, and 8-O-dGTP.

HY-138616S

dGTP-15N5 dilithium
dGTP- ¹⁵N₅ (2'-Deoxyguanosine-5'-triphosphate- ¹⁵N₅) dilithium is ¹⁵N labeled dGTP (HY-138616). dGTP (2'-Deoxyguanosine-5'-triphosphate), a guanosine nucleotide, can be used in deoxyribonucleic acid synthesis. Guanosine nucleotides (GDP, GTP, dGDP, and dGTP) are highly susceptible to oxidative damage to 8-oxo-GDP (8-O-GDP), 8-O-dGTP, 8-O-GTP, and 8-O-dGTP.

HY-138616S2

dGTP-15N5,d14 dilithium

dGTP- ¹⁵N₅,d₁₄ (2'-Deoxyguanosine-5'-triphosphate- ¹⁵N₅,d₁₄) dilithium is deuterium and ¹⁵N labeled dGTP (HY-138616). dGTP (2'-Deoxyguanosine-5'-triphosphate), a guanosine nucleotide, can be used in deoxyribonucleic acid synthesis. Guanosine nucleotides (GDP, GTP, dGDP, and dGTP) are highly susceptible to oxidative damage to 8-oxo-GDP (8-O-GDP), 8-O-dGTP, 8-O-GTP, and 8-O-dGTP.

HY-118830S1

13,14-Dihydro-15-keto prostaglandin D2-d9

13,14-Dihydro-15-keto prostaglandin D2-d₉ (DK-PGD2-d₉) is deuterium labeled 13,14-Dihydro-15-keto prostaglandin D2. 13, 14-Dihydro-15-keto prostaglandin D2 (DK-PGD2) is a PGD2 metabolite formed by the 15-hydroxyl PGDH pathway. 13, 14-Dihydro-15-keto prostaglandin D2 is a selective agonist for the DP2 receptor. 13, 14-Dihydro-15-keto prostaglandin D2 can inhibit ion flux in canine colonic mucosa preparation .

HY-W744340

*2-Oxo* Clopidogrel-d3**
2-Oxo Clopidogrel-d₃ is the deuterium labeled (±)-2-Oxo clopidogrel (HY-118025). (±)-2-Oxo clopidogrel is a metabolite of the antiplatelet agent Clopidogrel (HY-15283) .

HY-139492S

*Desdiacetyl-8-oxo* famciclovir-d4**
Desdiacetyl-8-oxo famciclovir-d₄ is the deuterium labeled Desdiacetyl-8-oxo famciclovir .

HY-125801S

*3-Oxo-5β-cholanoic acid-d4*
3-Oxo-5β-cholanoic acid-d₄ (Dehydrolithocholic acid-d₄) is the deuterium labeled 3-Oxo-5β-cholanoic acid (HY-125801). 3-Oxo-5β-cholanoic acid (Dehydrolithocholic acid), a bile acid metabolite, inhibits the diferentiation of TH17 cells by directly binding to the key transcription factor RORγt (K_d=1.13 μM) .

HY-43347S

*Benzyl 2-(4-(4-fluorobenzylcarbamoyl)-5-hydroxy-1-methyl-6-oxo-1,6-dihydropyrimidin-2-yl)propan-2-ylcarbamate-d3*
Benzyl 2-(4-(4-fluorobenzylcarbamoyl)-5-hydroxy-1-methyl-6-oxo-1,6-dihydropyrimidin-2-yl)propan-2-ylcarbamate-d₃ is the deuterium labeled Benzyl 2-(4-(4-fluorobenzylcarbamoyl)-5-hydroxy-1-methyl-6-oxo-1,6-dihydropyrimidin-2-yl)propan-2-ylcarbamate .

HY-139456S

*1-(4-Aza-8-hydroxy-6-oxo)oct-2-en-1-oylimidazole-d3*
1-(4-Aza-8-hydroxy-6-oxo)oct-2-en-1-oylimidazole-d₃ is the deuterium labeled 1-(4-Aza-8-hydroxy-6-oxo)oct-2-en-1-oylimidazole .

HY-181633S

*1,1-Dimethylbutyl N-[2-[[2-[7-[[2-(acetylamino)-2-deoxy-α-D-glucopyranosyl]oxy]-2-oxo-2H-1-benzopyran-4-yl]acetyl]amino]ethyl]carbamate-d4*
1,1-Dimethylbutyl N-[2-[[2-[7-[[2-(acetylamino)-2-deoxy-α-D-glucopyranosyl]oxy]-2-oxo-2H-1-benzopyran-4-yl]acetyl]amino]ethyl]carbamate-d₄ is the deuterium labeled 1,1-Dimethylbutyl N-[2-[[2-[7-[[2-(acetylamino)-2-deoxy-α-D-glucopyranosyl]oxy]-2-oxo-2H-1-benzopyran-4-yl]acetyl]amino]ethyl]carbamate.

HY-181632S

*1,1-Dimethylpentyl N-[2-[[2-[7-[[2-(acetylamino)-2-deoxy-α-D-glucopyranosyl]oxy]-2-oxo-2H-1-benzopyran-4-yl]acetyl]amino]ethyl]carbamate-d4*
1,1-Dimethylpentyl N-[2-[[2-[7-[[2-(acetylamino)-2-deoxy-α-D-glucopyranosyl]oxy]-2-oxo-2H-1-benzopyran-4-yl]acetyl]amino]ethyl]carbamate-d₄ is the deuterium labeled 1,1-Dimethylpentyl N-[2-[[2-[7-[[2-(acetylamino)-2-deoxy-α-D-glucopyranosyl]oxy]-2-oxo-2H-1-benzopyran-4-yl]acetyl]amino]ethyl]carbamate.

HY-181630S

*C-(1,1-Dimethylpropyl) N-[2-[[2-[7-[[2-deoxy-2-(sulfoamino)-α-D-glucopyranosyl]oxy]-2-oxo-2H-1-benzopyran-4-yl]acetyl]amino]ethyl]carbamate-d4*
C-(1,1-Dimethylpropyl) N-[2-[[2-[7-[[2-deoxy-2-(sulfoamino)-α-D-glucopyranosyl]oxy]-2-oxo-2H-1-benzopyran-4-yl]acetyl]amino]ethyl]carbamate-d₄ is the deuterium labeled C-(1,1-Dimethylpropyl) N-[2-[[2-[7-[[2-deoxy-2-(sulfoamino)-α-D-glucopyranosyl]oxy]-2-oxo-2H-1-benzopyran-4-yl]acetyl]amino]ethyl]carbamate.

HY-182093S

Momelotinib Metabolite M21-d4
N-(Cyanomethyl)-4-(2-((4-(3-oxo-4-morpholinyl)phenyl)amino)-4-pyrimidinyl)benzamide-d₄ is the deuterium labeled N-(Cyanomethyl)-4-(2-((4-(3-oxo-4-morpholinyl)phenyl)amino)-4-pyrimidinyl)benzamide.

Host:	Rabbit (3)
Reactivity:	Human (2) Mouse (1) Rat (1) Species independent (1)
Application:	IHC-P (2) ICC/IF (1) IF-Tissue (1) IP (1) WB (2) IHC-F (2) ELISA (2)
Isotype:	IgG (3)
Conjugation:	Non-conjugated (3)
Clonality:	Polyclonal (2) Monoclonal (1) Recombinant (1)
Modification:	Unmodified (3)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P81140

	8-OHdG (DNA/RNA Damage) Antibody 10+ Cited Publications 8-hydroxy-2'-deoxyguanosine; 2'-Deoxy-8-OXOguanosine; 7,8-Dihydro-8-OXO-2'-deoxyguanosine; 8-OXO-7,8-dihydro-2'-deoxyguanosine; 8-OXO-7,8-dihydrodeoxyguanosine; 2'-Deoxy-8-OXO-D-guanosine; 8-OXO-7,8-dihydro-2μ-deoxyguanosine,8-OXO-dG; 2'-Deoxy-8-hydroxyguanosine;	IHC-P, IHC-F, ELISA, IF-Tissue	Species independent
	8-OHdG (DNA/RNA Damage) Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to 8-OHdG (DNA/RNA Damage).

HY-P81206

	SRD5A2 Antibody (YA3540) 3 OXO 5 alpha steroid 4 dehydrogenase 2 antibody; 3-OXO-5-alpha-steroid 4-dehydrogenase 2 antibody; 5 alpha SR2 antibody; 5 alpha-SR2 antibody; 5ART2 antibody; e II 5 alpha reductase antibody; EC antibody; MGC138457 antibody; Micropenis, included antibody; S5A2_HUMAN antibody; S5AR 2 antibody; SR type 2 antibody; SRD5A2 antibody; Steroid 5 alpha reductase 2 antibody; Steroid 5-alpha-reductase 2 antibody; Steroid-5-alpha-reductase, alpha polypeptide 2 (3-OXO-5 alpha-steroid delta 4-dehydrogenase alpha 2) antibody; Type II 5-alpha reductase antibody;	WB, IP	Human, Rat
	SRD5A2 Antibody (YA3540) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to SRD5A2.

HY-P81071

	DLST Antibody 2-OXOglutarate dehydrogenase complex component E2; Dihydrolipoamide S succinyltransferase (E2 component of 2 OXO glutarate complex); Dihydrolipoamide S succinyltransferase; Dihydrolipoamide succinyltransferase component of 2 OXOglutarate dehydrogenase complex; Dihydrolipoamide succinyltransferase component of 2-OXOglutarate dehydrogenase complex; Dihydrolipoyllysine residue succinyltransferase component of 2 OXOglutarate dehydrogenase complex; Dihydrolipoyllysine residue succinyltransferase component of 2 OXOglutarate dehydrogenase complex mitochondrial; Dihydrolipoyllysine-residue succinyltransferase component of 2-OXOglutarate dehydrogenase complex; Dlst; DLTS; E2; E2K; mitochondrial; ODO2_HUMAN; OGDC-E2.	WB, ELISA, IHC-P, IHC-F, ICC/IF	Human, Mouse
	DLST Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to DLST.

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Cat. No.	Product Name		Classification

HY-152352

*7,8-Dihydro-8-oxo-7-propargyl guanosine*		Alkynes
7,8-Dihydro-8-oxo-7-propargyl guanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 7,8-Dihydro-8-oxo-7-propargyl guanosine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-154284

*7,8-Dihydro-8-oxo-7-propargyl-3’-deoxy guanosine*		Alkynes
7,8-Dihydro-8-oxo-7-propargyl-3’-deoxy guanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 7,8-Dihydro-8-oxo-7-propargyl-3’-deoxy guanosine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-152338

*7-Propargyl-7,8-dihydro-8-oxo-9-(β-D-xylofuranosyl)guanine*		Alkynes
7-Propargyl-7,8-dihydro-8-oxo-9-(β-D-xylofuranosyl)guanine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 7-Propargyl-7,8-dihydro-8-oxo-9-(β-D-xylofuranosyl)guanine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-152364

*7,8-Dihydro-8-oxo-7-propargyl-3’-deoxy-3’-fluoro guanosine*		Alkynes
7,8-Dihydro-8-oxo-7-propargyl-3’-deoxy-3’-fluoro guanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 7,8-Dihydro-8-oxo-7-propargyl-3’-deoxy-3’-fluoro guanosine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-152373

*7,8-Dihydro-8-oxo-7-propargyl-3’-deoxy-3’-fluoro-xylo-guanosine*		Alkynes
7,8-Dihydro-8-oxo-7-propargyl-3’-deoxy-3’-fluoro-xylo-guanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 7,8-Dihydro-8-oxo-7-propargyl-3’-deoxy-3’-fluoro-xylo-guanosine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-154283

*2-Amino-7-propargyl-7,8-dihydro-8-oxo-9-(beta-D-xylofuranosyl)purine*		Alkynes
2-Amino-7-propargyl-7,8-dihydro-8-oxo-9-(beta-D-xylofuranosyl)purine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 2-Amino-7-propargyl-7,8-dihydro-8-oxo-9-(beta-D-xylofuranosyl)purine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-154425

*2-Amino-7-propargyl-7,8-dihydro-8-oxo-9-(beta-D-3-deoxy-ribofuranosyl)purine*		Alkynes
2-Amino-7-propargyl-7,8-dihydro-8-oxo-9-(beta-D-3-deoxy-ribofuranosyl)purine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 2-Amino-7-propargyl-7,8-dihydro-8-oxo-9-(beta-D-3-deoxy-ribofuranosyl)purine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-W882740

*4-Nitrophenyl 11,16-dioxo-14,14-bis(3-oxo-3-((2-(2-(prop-2-yn-1-yloxy)ethoxy)ethyl)amino)propyl)-4,7-dioxa-10,15-diazaicos-1-yn-20-oate*		Alkynes
4-Nitrophenyl 11,16-dioxo-14,14-bis(3-oxo-3-((2-(2-(prop-2-yn-1-yloxy)ethoxy)ethyl)amino)propyl)-4,7-dioxa-10,15-diazaicos-1-yn-20-oate is a biological molecule.

HY-Z8670

Ethinylestradiol impurity 2 16-OXO ethynyl estradiol		Alkynes
Ethinylestradiol impurity 2 (16-Oxo ethynyl estradiol) is an impurity of Ethinylestradiol.

HY-205199

DMT-2'-O-propynyl-G(Ac)-CE-phosphoramidite		Alkynes
(2R,3R,4R,5R)-5-(2-Acetamido-6-oxo-3,6-dihydro-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(prop-2-yn-1-yloxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite is a phosphoramidite that can be used in the synthesis of oligonucleotides.

Cat. No.	Product Name		Classification

HY-W011540

8-Hydroxy-2'-deoxyguanosine 5+ Cited Publications 8-OXO-2-deoxyguanosine		Nucleoside Analogs Guanosine
8-Hydroxy-2'-deoxyguanosine is a critical biomarker of oxidative stress and carcinogenesis.

HY-138616

dGTP 2'-Deoxyguanosine-5'-triphosphate		Nucleotide Analogs
dGTP (2'-Deoxyguanosine-5'-triphosphate) is one of the precursors for DNA synthesis, and serves as a direct substrate for DNA replication and repair. dGTP is prone to oxidative damage; under the action of reactive oxygen species and other factors, dGTP is oxidized to form 8-oxo-dGTP .

HY-152431

*1-Amino-7,8-dihydro-8-oxo-9-(β-D-xylofuranosyl) guanine*		Nucleoside Analogs Guanosine
1-Amino-7,8-dihydro-8-oxo-9-(β-D-xylofuranosyl) guanine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-43066

DMT-2'-O-TBDMS-G(dmf)-CE-phosphoramidite		Phosphoramidites Guanine
(2R,3R,4R,5R)-2-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-((tert-butyldimethylsilyl)oxy)-5-(2-(((E)-(dimethylamino)methylene)amino)-6-oxo-1,6-dihydro-9H-purin-9-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite is a phosphoramidite that can be used in the synthesis of oligonucleotides.

HY-152352

*7,8-Dihydro-8-oxo-7-propargyl guanosine*		Nucleoside Analogs Guanosine
7,8-Dihydro-8-oxo-7-propargyl guanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 7,8-Dihydro-8-oxo-7-propargyl guanosine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-154284

*7,8-Dihydro-8-oxo-7-propargyl-3’-deoxy guanosine*		Nucleoside Analogs Guanosine
7,8-Dihydro-8-oxo-7-propargyl-3’-deoxy guanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 7,8-Dihydro-8-oxo-7-propargyl-3’-deoxy guanosine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-152338

*7-Propargyl-7,8-dihydro-8-oxo-9-(β-D-xylofuranosyl)guanine*		Nucleoside Analogs Guanosine
7-Propargyl-7,8-dihydro-8-oxo-9-(β-D-xylofuranosyl)guanine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 7-Propargyl-7,8-dihydro-8-oxo-9-(β-D-xylofuranosyl)guanine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-152364

*7,8-Dihydro-8-oxo-7-propargyl-3’-deoxy-3’-fluoro guanosine*		Nucleoside Analogs Guanosine
7,8-Dihydro-8-oxo-7-propargyl-3’-deoxy-3’-fluoro guanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 7,8-Dihydro-8-oxo-7-propargyl-3’-deoxy-3’-fluoro guanosine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-152373

*7,8-Dihydro-8-oxo-7-propargyl-3’-deoxy-3’-fluoro-xylo-guanosine*		Nucleoside Analogs Guanosine
7,8-Dihydro-8-oxo-7-propargyl-3’-deoxy-3’-fluoro-xylo-guanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 7,8-Dihydro-8-oxo-7-propargyl-3’-deoxy-3’-fluoro-xylo-guanosine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-152604

*3,4-Dihydro-3-oxo-4-β-D-ribofuranosyl-2-pyrazinecarboxamide*		Nucleoside Analogs
3,4-Dihydro-3-oxo-4-β-D-ribofuranosyl-2-pyrazinecarboxamide is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-152341

*7-(Butyn-2-yl)-7,8-dihydro-8-oxo-9-(β-D-xylofuranosyl)guanine*		Nucleoside Analogs Guanosine
7-(Butyn-2-yl)-7,8-dihydro-8-oxo-9-(β-D-xylofuranosyl)guanine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 7-(Butyn-2-yl)-7,8-dihydro-8-oxo-9-(β-D-xylofuranosyl)guanine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-154283

*2-Amino-7-propargyl-7,8-dihydro-8-oxo-9-(beta-D-xylofuranosyl)purine*		Nucleoside Analogs
2-Amino-7-propargyl-7,8-dihydro-8-oxo-9-(beta-D-xylofuranosyl)purine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 2-Amino-7-propargyl-7,8-dihydro-8-oxo-9-(beta-D-xylofuranosyl)purine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-152328

*7-Ethyl-7,8-dihydro-8-oxo-9-(β-D-xylofuranosyl)guanine*		Nucleoside Analogs Guanosine
7-Ethyl-7,8-dihydro-8-oxo-9-(β-D-xylofuranosyl)guanine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-152436

*7-Cyclopropylmethyl-7,8-dihydro-8-oxo-9-(β-D-xylofuranosyl) guanine*		Nucleoside Analogs Guanosine
7-Cyclopropylmethyl-7,8-dihydro-8-oxo-9-(β-D-xylofuranosyl) guanine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-152407

*7-Allyl-7,8-dihydro-8-oxo-9-(β-D-xylofuranosyl) guanine*		Nucleoside Analogs Guanosine
7-Allyl-7,8-dihydro-8-oxo-9-(β-D-xylofuranosyl) guanine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-152491

*7-Cyclopropyl methyl-7,8-dihydro-8-oxo-9-(β-D-ribofuranosyl)guanine*		Nucleoside Analogs Guanosine
7-Cyclopropyl methyl-7,8-dihydro-8-oxo-9-(β-D-ribofuranosyl)guanine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-152331

*7-n-Propyl-7,8-dihydro-8-oxo-9-(β-D-xylofuranosyl)guanine*		Nucleoside Analogs Guanosine
7-n-Propyl-7,8-dihydro-8-oxo-9-(β-D-xylofuranosyl)guanine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-152333

*7-n-Butyl-7,8-dihydro-8-oxo-9-(β-D-xylofuranosyl)guanine*		Nucleoside Analogs Guanosine
7-n-Butyl-7,8-dihydro-8-oxo-9-(β-D-xylofuranosyl)guanine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-152872

*Uridine-5-oxo-acetyl-(9-fluorenylmethyl) ester*		Nucleoside Analogs Uridine
Uridine-5-oxo-acetyl-(9-fluorenylmethyl) ester is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-154425

*2-Amino-7-propargyl-7,8-dihydro-8-oxo-9-(beta-D-3-deoxy-ribofuranosyl)purine*		Nucleoside Analogs
2-Amino-7-propargyl-7,8-dihydro-8-oxo-9-(beta-D-3-deoxy-ribofuranosyl)purine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 2-Amino-7-propargyl-7,8-dihydro-8-oxo-9-(beta-D-3-deoxy-ribofuranosyl)purine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-152432

*1-Amino-7-cyclopropyl methyl-7,8-dihydro-8-oxo-9-(β-D-xylofuranosyl)guanine*		Nucleoside Analogs Guanosine
1-Amino-7-cyclopropyl methyl-7,8-dihydro-8-oxo-9-(β-D-xylofuranosyl)guanine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-152703

*2-Amino-7-cyclopropyl methyl-7,8-dihydro-8-oxo-9-(beta-D-xylo furanosyl)purine*		Nucleoside Analogs
2-Amino-7-cyclopropyl methyl-7,8-dihydro-8-oxo-9-(beta-D-xylo furanosyl)purine (G159-82) PTPD-2 Confidential is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-154613

*(2R-cis)-5-[Tetrahydro-5-(hydroxymethyl)-4-oxo-2-furanyl]-2,4(1H,3H)-pyrimidinedione*		Nucleoside Analogs
(2R-cis)-5-[Tetrahydro-5-(hydroxymethyl)-4-oxo-2-furanyl]-2,4(1H,3H)-pyrimidinedione is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-152991

*6-Deoxo-8-oxo-3’-deoxy-guanosine*		Nucleoside Analogs Guanosine
2′-Deoxy-N-(2-furanylmethyl)guanosine is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7) .

HY-152770

*6-(2-O-Methyl-beta-D-ribofuranosyl)-3-(2-oxo-propyl)-6H-imidazo[1,2-c]pyrimidin-5-one*		Nucleoside Analogs
6-((2R,3R,4R,5R)-4-Hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)-3-(2-oxopropyl)imidazo[1,2-c]pyrimidin-5(6H)-one is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-112817A

*8-Oxo-dGTP trisodium solution (100 mM)* 8-OXO-Deoxyguanosine triphosphate trisodium		Nucleotide Analogs Guanine Nucleotide
8-Oxo-dGTP (8-Oxo-Deoxyguanosine triphosphate) trisodium solution (100mM) is an oxidized guanine nucleotide formed by ROS-mediated oxidative modification of dGTP, and it also serves as a key substrate for 8-oxo-dGTP pyrophosphohydrolases (such as hMTH1 and E. coli MutT). 8-Oxo-dGTP trisodium solution (100mM) acts as a DNA mutagen, inserts into nascent DNA and pairs with adenine and cytosine, inducing A:T to C:G transversion mutations. Furthermore, 8-Oxo-dGTP trisodium solution (100mM) causes oxidative DNA base modification, strand breakage and S-phase arrest, and ultimately triggers AIF-mediated apoptosis and promotes spontaneous carcinogenesis in mth1-deficient mice. Accumulation of 8-Oxo-dGTP trisodium solution (100mM) in cells induces genomic instability, but it exhibits a tumor-suppressive effect that reduces tumor incidence in mouse models instead. 8-Oxo-dGTP trisodium solution (100mM) is widely used in studies related to spontaneous carcinogenesis, Parkinson's disease, Alzheimer's disease, heart failure and tumor mechanisms .

HY-W778087

*5-Aza-2'-deoxy-6-oxo* cytidine**		Nucleoside Analogs Nucleotide Analogs
5-Aza-2'-deoxy-6-oxo cytidine is a monomeric raw material that can be used for nucleic acid synthesis.

HY-182154

*8-Oxo-dA-CE phosphoramidite*		Phosphoramidites Adenine
8-Oxo-dA-CE phosphoramidite is a phosphoramidite that can be used in the synthesis of oligonucleotides.

HY-W1121772

*8-Oxo-dG(dmf) phosphoramidite*		Phosphoramidites Guanine
8-Oxo-dG(dmf)phosphoramidite is a phosphoramidite that can be used in the synthesis of oligonucleotides.

HY-W854193

*8-Oxo-dG-CE phosphoramidite*		Phosphoramidites Guanine
Guanosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-7,8-dihydro-N-(2-methyl-1-oxopropyl)-8-oxo-, 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite] is a phosphoramidite that can be used in the synthesis of oligonucleotides.

HY-172731

*8-Oxo-dATP lithium*		Nucleoside Analogs Adenosine
8-Oxo-dATP lithium, as an oxidized purine nucleoside triphosphate, is hydrolyzed by MTH1 into monophosphates, thereby preventing errors caused by its misincorporation during DNA replication or transcription .

HY-206075

5'-Hydrazide-modifier-6 cep		Phosphoramidites Other Phosphoramidite
2-Cyanoethyl (6-oxo-6-(2-tritylhydrazinyl)hexyl) diisopropylphosphoramidite is a phosphoramidite that can be used in the synthesis of oligonucleotides.

HY-W784553

Amino-modifier-C6-dC CEP		Phosphoramidites Thymine
(2R,3S,5R)-2-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(4-(((dimethylamino)methylene)amino)-2-oxo-5-(3-oxo-3-((6-(2,2,2-trifluoroacetamido)hexyl)amino)prop-1-en-1-yl)pyrimidin-1(2H)-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite is a phosphoramidite that can be used in the synthesis of oligonucleotides.

HY-169879

5'-Amino-Modifier TEG PDA		Phosphoramidites Other Phosphoramidite
2-Cyanoethyl (1-(2-(methylcarbamoyl)phenyl)-1-oxo-5,8,11-trioxa-2-azatridecan-13-yl) diisopropylphosphoramidite is a phosphoramidite that can be used in the synthesis of oligonucleotides.

HY-W791715

2′-Deoxy-5′-O-DMT-N2-methylguanosine-3′-CE phosphoramidite		Phosphoramidites Guanine
(2r,3s,5r)-2-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2-(methylamino)-6-oxo-1,6-dihydro-9h-purin-9-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite is a phosphoramidite that can be used in the synthesis of oligonucleotides.

HY-W892782

DMTr-TNA-C(Ac)-amidite		Phosphoramidites Cytosine
(2R,3R,4S)-2-[4-(Acetylamino)-2-oxo-1(2H)-pyrimidinyl]-4-[bis(4-methoxyphenyl)phenylmethoxy]tetrahydro-3-furanyl 2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite is a phosphoramidite that can be used in the synthesis of oligonucleotides.

HY-W784548

5'-O-DMT-2'-O-tert-Butyldimethylsilyl-inosine-3'-CE phosphoramidite		Phosphoramidites Guanine
(2R,3R,4R,5R)-2-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-((tert-butyldimethylsilyl)oxy)-5-(6-oxo-3,6-dihydro-9H-purin-9-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite is a phosphoramidite that can be used in the synthesis of oligonucleotides.

HY-W1009015

N2-iBu-Guanine bicyclo[3.2.0]-CE-diisopropylphosphoramidite		Phosphoramidites Guanine
(1R,4R,5S)-1-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3-(2-isobutyramido-6-oxo-1H-purin-9(6H)-yl)-2,6-dioxabicyclo[3.2.0]heptan-4-yl (2-cyanoethyl) diisopropylphosphoramidite is a phosphoramidite that can be used in the synthesis of oligonucleotides.

HY-W784560

DMTr-3'-O-TBDMS-rG(iBu)-CE Phosphoramidite		Phosphoramidites Guanine
(2S,3S,4S,5S)-2-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-((tert-butyldimethylsilyl)oxy)-5-(2-isobutyramido-6-oxo-3,6-dihydro-9H-purin-9-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite is a phosphoramidite that can be used in the synthesis of oligonucleotides.

HY-W1126881

(E)-(Dimethylamino)methylene-2'-F-dG-CE phosphoramidite		Phosphoramidites Guanine
(2R,3R,4R,5R)-2-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2-(((E)-(dimethylamino)methylene)amino)-6-oxo-3,6-dihydro-9H-purin-9-yl)-4-fluorotetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite is a phosphoramidite that can be used in the synthesis of oligonucleotides.

HY-205199

DMT-2'-O-propynyl-G(Ac)-CE-phosphoramidite		Phosphoramidites Guanine
(2R,3R,4R,5R)-5-(2-Acetamido-6-oxo-3,6-dihydro-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(prop-2-yn-1-yloxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite is a phosphoramidite that can be used in the synthesis of oligonucleotides.

HY-W714978

5'-O-DMT-3'-Me-dG(dmf)-CE phosphoramidite		Phosphoramidites Guanine
(2R,3S,5R)-2-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2-(((E)-(dimethylamino)methylene)amino)-5-methyl-4-oxo-3,4-dihydro-7H-pyrrolo[2,3-d]pyrimidin-7-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite is a phosphoramidite that can be used in the synthesis of oligonucleotides.

HY-W714955

2'-O-Methyl-pyrrolo C CEP		Phosphoramidites Other Phosphoramidite
(2R,3R,4R,5R)-2-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-methoxy-5-(6-methyl-2-oxo-2,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-3-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite is a phosphoramidite that can be used in the synthesis of oligonucleotides.

HY-W784554

5'-DMTr-Amino-modifier-C6-dT-3'-CE-phosphoramidite		Phosphoramidites Uracil
(2R,3S,5R)-2-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2,4-dioxo-5-((E)-3-oxo-3-((6-(2,2,2-trifluoroacetamido)hexyl)amino)prop-1-en-1-yl)-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite is a phosphoramidite that can be used in the synthesis of oligonucleotides.

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