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Cat. No.: HY-117581

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L-669,262

(Synonyms: 6-Oxo Simvastatin; Iso-simvastatin-6-one)

L-669,262, a potent inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase, with an IC₅₀ of 0.10 ng/mL for rat liver HMG-CoA.

For research use only. We do not sell to patients.

CAS No.: 130468-11-0
Formula: C₂₅H₃₆O₆
Molecular Weight:432.55

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (273 KB)

L-669,262 Chemical Structure

CAS No.: 130468-11-0

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

L-669,262, a potent inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase, with an IC₅₀ of 0.10 ng/mL for rat liver HMG-CoA^[1].

Chemical Information

CAS No. 130468-11-0
Molecular Weight 432.55
Formula C₂₅H₃₆O₆
SMILES

CCC(C)(C(O[C@H]1CC(C)=CC2=CC([C@@H]([C@@H]([C@@]12[H])CC[C@@H]3C[C@H](CC(O3)=O)O)C)=O)=O)C
Synonyms

6-Oxo Simvastatin; Iso-simvastatin-6-one
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (273 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Joshua H, et, al. L-669,262, a potent HMG-CoA reductase inhibitor. J Antibiot (Tokyo). 1991 Mar;44(3):366-70. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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