2-Hydroxy-6-oxo-1(10),7(11)-germacradien-12,8-olide
2-Hydroxy-6-oxo-1(10),7(11)-germacradien-12,8-olide ((1(10)E,2α,4β,8α)-form,2-Meether) is a furanosesquiterpenoid neuroprotective agent that exhibits neuroprotective effect against MPP+-induced neuronal cell death. 2-Hydroxy-6-oxo-1(10),7(11)-germacradien-12,8-olide can be used for the research of parkinson's disease.
For research use only. We do not sell to patients.
- CAS No.: 1042109-84-1
- Formula: C16H22O4
- Molecular Weight:278.34
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
In Vitro
2-Hydroxy-6-oxo-1(10),7(11)-germacradien-12,8-olide (Compound 9) (3-30 μM) exhibits moderate neuroprotective effects against MPP+-induced cell death in SH-SY5Y neuroblastoma cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1042109-84-1
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Molecular Weight 278.34
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Formula C16H22O4
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SMILES
O=C1C(C)=C(C(C[C@@H](C)CC(OC)/C=C(C)/C2)=O)[C@@]2([H])O1
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Synonyms
(1(10)E,2α,4β,8α)-form,2-Meether
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
2-Hydroxy-6-oxo-1(10),7(11)-germacradien-12,8-olide Related Classifications
HY-N18155 Related Classifications
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