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(S)-2-Hydroxypropylphosphonic acid epoxidase

(S)-2-Hydroxypropylphosphonic acid epoxidase (EC 1.11.1.23) is the last enzyme in the biosynthetic pathway of fosfomycin, a broad-spectrum antibiotic produced by certain Streptomyces species. Contains non heme iron that forms a iron (IV)-oxo (ferryl) complex with hydrogen peroxide, which functions as a proton abstractor from the substrate.

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  • (S)-2-Hydroxypropylphosphonic acid epoxidase Chemical Structure
    (S)-2-Hydroxypropylphosphonic acid epoxidase Chemical Structure
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  • (S)-2-Hydroxypropylphosphonic acid epoxidase Chemical Structure
    (S)-2-Hydroxypropylphosphonic acid epoxidase Chemical Structure
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  • (S)-2-Hydroxypropylphosphonic acid epoxidase