7-epi-10-Oxo-10-deacetyl baccatin III
7-epi-10-Oxo-10-deacetyl baccatin III (10-Dehydrobaccatin V) can be isolated from the degradation impurities in Docetaxel (HY-B0011).
For research use only. We do not sell to patients.
- CAS No.: 151636-94-1
- Formula: C29H34O10
- Molecular Weight:542.57
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| A2780 | IC50 |
4.89 μM
Compound: 5
|
Cytotoxicity against human A2780 cells by MTT assay
Cytotoxicity against human A2780 cells by MTT assay
|
[PMID: 18001087] |
| A549 | IC50 |
<10 μM
Compound: 5
|
Cytotoxicity against human A549 cells by MTT assay
Cytotoxicity against human A549 cells by MTT assay
|
[PMID: 18001087] |
| Bel-7402 | IC50 |
<10 μM
Compound: 5
|
Cytotoxicity against human Bel7402 cells by MTT assay
Cytotoxicity against human Bel7402 cells by MTT assay
|
[PMID: 18001087] |
| BGC-823 | IC50 |
1.38 μM
Compound: 5
|
Cytotoxicity against human BGC823 cells by MTT assay
Cytotoxicity against human BGC823 cells by MTT assay
|
[PMID: 18001087] |
| HCT-8 | IC50 |
<10 μM
Compound: 5
|
Cytotoxicity against human HCT8 cells by MTT assay
Cytotoxicity against human HCT8 cells by MTT assay
|
[PMID: 18001087] |
| NCI-H460 | IC50 |
60 μM
Compound: 4, 7-epi-10-oxo-10-DAB
|
Cytotoxicity against human H460 cells
Cytotoxicity against human H460 cells
|
[PMID: 19845390] |
| NCI-H460 | IC50 |
60 μM
Compound: 6
|
Cytotoxicity against human H460 cells
Cytotoxicity against human H460 cells
|
[PMID: 20527910] |
Chemical Information
-
CAS No. 151636-94-1
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Molecular Weight 542.57
-
Formula C29H34O10
-
SMILES
[H][C@@]1([C@@]2(C)[C@H](O)C[C@@H]3[C@@]1(OC(C)=O)CO3)[C@H](OC(C4=CC=CC=C4)=O)[C@]5(O)C[C@H](O)C(C)=C(C(C2=O)=O)C5(C)C
-
Synonyms
10-Dehydrobaccatin V
-
Structure Classification
-
Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)