Taxus baccata L.

Baccatin VI is a natural taxoid with antinociceptive activities. Baccatin VI possesses significant antinociceptive activity against p-Benzoquinone-induced abdominal contractions.

Secoisolariciresinol dimethyl ether diacetate is a dibenzylbutane lignan that can be found in Justicia procumbens L. It is a component of the ethyl acetate extract of Justicia procumbens L. and can be detected in rat plasma after oral administration of this extract. Secoisolariciresinol dimethyl ether diacetate can be used in studies of lignans, natural products, and plasma pharmaceutical chemistry.

10-Deacetylcephalomannine is a taxane that can be isolated from the bark of Taxus baccata L..

7-epi-10-Oxo-10-deacetyl baccatin III (10-Dehydrobaccatin V) can be isolated from the degradation impurities in Docetaxel (HY-B0011).

Taxiresinol is an orally active and potent lignan, that can be isolated from the heartwood of Taxus baccata. Taxiresinol shows significant antinociceptive activity.

Isotaxiresinol is a lignan, which can be isolated from Taxus yunnanensis and has the function of plant metabolites.

Sequoiaflavone is a biflavonoid compound with multiple activities. Sequoiaflavone suppresses hepatic CYP1A1/(7-Ethoxycoumarin O-deethylase) ECOD, prevents Aβ_1-42 fibrillization (IC₅₀ = 0.29 μM) and disaggregates amyloid fibrils (EC₅₀ = 2.04 μM), inhibits Alternaria alternata and inhibits human recombinant PDE5A1 overexpressed in COS-7 cells (IC₅₀ = 19.9 μM) to exert NO-independent vasodilation. Sequoiaflavone can be used in Alzheimer's disease, peripheral circulatory disorder, and antifungal research.

Taxcultine is a Diterpenoids product that can be isolated from the cell cultures of Taxus baccata..

9-Deacetyl-9-benzoyl-10-debenzoyltaxchinin A is a Diterpenoids product that can be isolated from the stem-barks of Taxus baccata L. cv. stricta..

9-Deacetyl-9-benzoyl-10-debenzoyl-4β,20-epoxytaxchinin A is a Diterpenoids product that can be isolated from the stem-barks of Taxus baccata L. cv. stricta..

10-Deacetyl-13-oxobaccatin III is an taxane that can be isolated from Taxus sumatrana. 10-Deacetyl-13-oxobaccatin III (30 μg/mL) shows cytotoxicity against A498, NCI-H226, A549, PC-3 cells, with inhibition a rate of 29.7%, 49.2%, 43.9%, 65.3%.

7-epi-10-Deacetyl baccatin III can be isolated from the degradation impurities in Docetaxel (HY-B0011).