2. Natural Products
  3. Plants Phenylpropanoids
  4. Taxaceae Lignans
  5. Taxus baccata L.
  6. Taxiresinol

Taxiresinol is an orally active and potent lignan, that can be isolated from the heartwood of Taxus baccata. Taxiresinol shows significant antinociceptive activity.

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Taxiresinol Chemical Structure

Taxiresinol Chemical Structure

CAS No. : 40951-69-7

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Taxiresinol Related Antibodies

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Description

Taxiresinol is an orally active and potent lignan, that can be isolated from the heartwood of Taxus baccata. Taxiresinol shows significant antinociceptive activity[1].

In Vivo

Taxiresinol (100 mg/kg, oral administration, once) shows significant antinociceptive activity against p-benzoquinone-induced abdominal contractions in mice[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Male Swiss albino mice (20-25 g)[1]
Dosage: 100 mg/kg
Administration: Oral administration, sixty minutes after the oral administration of test sample, the mice were intraperitoneally injected with 0.1 ml/10 g body weight of 2.5% (v/v) p-benzoquinone solution in distilled H2O.
Result: Showed significant antinociceptive activity against p-benzoquinone-induced abdominal contractions (writhing movements) in mice, with a inhibitory ratio of 37.8%.
Molecular Weight

346.37

Formula

C19H22O6
CAS No.
SMILES

COC1=C(O)C=CC(C[C@H]2CO[C@H](C3=CC(O)=C(O)C=C3)[C@H]2CO)=C1
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Taxiresinol40951-69-7OthersAntinociceptive activityabdominal contractionswrithing movementsTaxus baccataorally activelignanInhibitorinhibitorinhibit

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