10-Deacetyl-13-oxobaccatin III
10-Deacetyl-13-oxobaccatin III is an taxane that can be isolated from Taxus sumatrana. 10-Deacetyl-13-oxobaccatin III (30 μg/mL) shows cytotoxicity against A498, NCI-H226, A549, PC-3 cells, with inhibition a rate of 29.7%, 49.2%, 43.9%, 65.3%.
For research use only. We do not sell to patients.
- CAS No.: 92950-42-0
- Formula: C29H34O10
- Molecular Weight:542.57
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HeLa | IC50 |
>10 μM
Compound: 15
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Cytotoxicity against human HeLa cells assessed as reduction in cell viability incubated for 72 hrs by WST-8 dye based assay
Cytotoxicity against human HeLa cells assessed as reduction in cell viability incubated for 72 hrs by WST-8 dye based assay
|
[PMID: 28240909] |
Chemical Information
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CAS No. 92950-42-0
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Molecular Weight 542.57
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Formula C29H34O10
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SMILES
O=C([C@]1(C)[C@@H](O)C[C@@H]2[C@](CO2)(OC(C)=O)[C@@]1([H])[C@H](OC(C3=CC=CC=C3)=O)[C@](C4(C)C)(O)C5)[C@H](O)C4=C(C)C5=O
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)