10-Deacetylcephalomannine
10-Deacetylcephalomannine is a taxane that can be isolated from the bark of Taxus baccata L..
For research use only. We do not sell to patients.
- CAS No.: 76429-85-1
- Formula: C43H51NO13
- Molecular Weight:789.86
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| A2780 | IC50 |
0.09 μM
Compound: 7
|
Cytotoxicity against human A2780 cells by MTT assay
Cytotoxicity against human A2780 cells by MTT assay
|
[PMID: 18001087] |
| A549 | IC50 |
<10 μM
Compound: 7
|
Cytotoxicity against human A549 cells by MTT assay
Cytotoxicity against human A549 cells by MTT assay
|
[PMID: 18001087] |
| Bel-7402 | IC50 |
2.69 μM
Compound: 7
|
Cytotoxicity against human Bel7402 cells by MTT assay
Cytotoxicity against human Bel7402 cells by MTT assay
|
[PMID: 18001087] |
| BGC-823 | IC50 |
0.1 μM
Compound: 7
|
Cytotoxicity against human BGC823 cells by MTT assay
Cytotoxicity against human BGC823 cells by MTT assay
|
[PMID: 18001087] |
| HCT-8 | IC50 |
3.29 μM
Compound: 7
|
Cytotoxicity against human HCT8 cells by MTT assay
Cytotoxicity against human HCT8 cells by MTT assay
|
[PMID: 18001087] |
| KB | IC50 |
0.0015 μg/mL
Compound: 56
|
Cytotoxicity against human KB cells
Cytotoxicity against human KB cells
|
[PMID: 14987066] |
| KB | ED50 |
0.31 ng/mL
Compound: 4
|
Cytotoxicity against human KB cells
Cytotoxicity against human KB cells
|
[PMID: 7264680] |
| KB | ED50 |
3.1 x 10-2 μg/mL
Compound: 4
|
Cytotoxicity against human KB cells
Cytotoxicity against human KB cells
|
[PMID: 7264680] |
Chemical Information
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CAS No. 76429-85-1
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Molecular Weight 789.86
-
Formula C43H51NO13
-
SMILES
CC(O[C@]([C@@]1([H])C[C@@H]2O)(CO1)[C@@]([C@@]2(C([C@@H]3O)=O)C)([H])[C@@H]([C@@](C(C)(C3=C4C)C)(C[C@@H]4OC([C@H](O)[C@H](C5=CC=CC=C5)NC(/C(C)=C/C)=O)=O)O)OC(C6=CC=CC=C6)=O)=O
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Synonyms
10-Deacetyltaxol B
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)