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Cat. No.: HY-N13077

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3-Oxo-resibufogenin

3-Oxo-resibufogenin is an important bufadienolide with significant biological activity and potential anti-cancer properties.

For research use only. We do not sell to patients.

CAS No.: 62859-80-7
Formula: C₂₄H₃₀O₄
Molecular Weight:382.49

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (272 KB)

3-Oxo-resibufogenin Chemical Structure

CAS No.: 62859-80-7

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

3-Oxo-resibufogenin is an important bufadienolide with significant biological activity and potential anti-cancer properties^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
MH60	IC₅₀	2.4 μM Compound: 8	Growth inhibition of IL6-dependent mouse MH60 cells after 72 hrs by MTT assay in presence of human recombinant IL6 Growth inhibition of IL6-dependent mouse MH60 cells after 72 hrs by MTT assay in presence of human recombinant IL6	[PMID: 15620253]
MH60	IC₅₀	8.4 μM Compound: 8	Growth inhibition of IL-6-independent mouse MH60 cells after 72 hrs by MTT assay Growth inhibition of IL-6-independent mouse MH60 cells after 72 hrs by MTT assay	[PMID: 15620253]

Chemical Information

CAS No. 62859-80-7
Molecular Weight 382.49
Formula C₂₄H₃₀O₄
SMILES

C[C@]12[C@@]3([C@@]4([H])[C@]([C@@]5([C@](CC(CC5)=O)([H])CC4)C)([H])CC2)[C@](C[C@@H]1C(C=C6)=COC6=O)([H])O3
Structure Classification
- Steroids
Initial Source
- Microorganisms
Actinomucor elegans AS
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (272 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Mou L Y, et al. Biotransformation of resibufogenin by Actinomucor elegans[J]. Journal of Asian natural products research, 2014, 16(6): 623-628.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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