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Cat. No.: HY-N1639

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1-Decarboxy-3-oxo-ceanothic acid

(Synonyms: DOCA)

1-Decarboxy-3-oxo-ceanothic acid is an anticancer agent. 1-Decarboxy-3-oxo-ceanothic acid inhibits DNA synthesis. 1-Decarboxy-3-oxo-ceanothic acid induces Apoptosis.

For research use only. We do not sell to patients.

CAS No.: 214150-74-0
Formula: C₂₉H₄₄O₃
Molecular Weight:440.66

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

1-Decarboxy-3-oxo-ceanothic acid Chemical Structure

CAS No.: 214150-74-0

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

1-Decarboxy-3-oxo-ceanothic acid is an anticancer agent. 1-Decarboxy-3-oxo-ceanothic acid inhibits DNA synthesis. 1-Decarboxy-3-oxo-ceanothic acid induces Apoptosis^[1].

All DNA/RNA Synthesis Isoforms :

Cellular Effect

Cell Line	Type	Value	Description	References
HeLa	IC₅₀	6.6 μg/mL Compound: 2	Cytotoxicity against human HeLa cells after 48 hrs by MTT assay Cytotoxicity against human HeLa cells after 48 hrs by MTT assay	[PMID: 9834149]
OVCAR-3	IC₅₀	2.8 μg/mL Compound: 2	Cytotoxicity against human OVCAR-3 cells after 48 hrs by MTT assay Cytotoxicity against human OVCAR-3 cells after 48 hrs by MTT assay	[PMID: 9834149]
Raji	IC₅₀	442 molar ratio Compound: 15	Inhibition of TPA-induced EBV-early antigen activation in human Raji cells assessed as EA induction after 48 hrs relative to TPA Inhibition of TPA-induced EBV-early antigen activation in human Raji cells assessed as EA induction after 48 hrs relative to TPA	[PMID: 19481937]

Chemical Information

CAS No. 214150-74-0
Molecular Weight 440.66
Formula C₂₉H₄₄O₃
SMILES

OC([C@]12[C@@]([C@@H](CC2)C(C)=C)([H])[C@]3([H])[C@@](CC1)([C@]4([C@]([C@@]5([C@@](C(C)(C(C5)=O)C)([H])CC4)C)([H])CC3)C)C)=O
Synonyms

DOCA
Structure Classification
- Terpenoids
- Triterpenes
Initial Source
- Animals
human ovarian adenocarcinoma (OVCAR-3) cells
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Su Y, et al. In vitro cytotoxic activity of 1-decarboxy-3-oxo-ceanothic acid in a human ovarian adenocarcinoma cell line. Res Commun Mol Pathol Pharmacol. 1998 Jun;100(3):313-26. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
- Description
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References

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1-Decarboxy-3-oxo-ceanothic acid

All DNA/RNA Synthesis Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

1-Decarboxy-3-oxo-ceanothic acid Related Classifications

HY-N1639 Related Classifications