3-Oxo-hop-22(29)-ene
3-Oxo-hop-22(29)-ene is a yeast α-glucosidase inhibitor. 3-Oxo-hop-22(29)-ene shows a moderate effect on the viability of T. cruzi and L. mexicana. 3-Oxo-hop-22(29)-ene shows marginal activity of anti-inflammatory.
For research use only. We do not sell to patients.
- CAS No.: 25615-11-6
- Formula: C30H48O
- Molecular Weight:424.70
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
In Vitro
3-Oxo-hop-22(29)-ene (compound 2) (50 μM; 24 hours) reduces the viability of T. cruzi by more than 20%, and has a moderate effecton on T. rangeli and L. mexicana[1].
3-Oxo-hop-22(29)-ene (10, 100 μM; 48 hours) causes 1.51% and 7.39% inhibition activity to yeast α-glucosidase respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:Saccharomyces cerevisiae (type 1) and mammalian yeast (type 2) α-glucosidases, T. cruzi, T. rangeli, L. mexicana
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Concentration:10 μM, 50 μM, 100 μM
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Incubation Time:24 hours, 48 hours
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Result:Reduced the viability of T. cruzi by more than 20%, and had a moderate effecton on T. rangeli and L. mexicana
Inhibited Yeast α-glucosidase.
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Adult male CD-1 mice (25-30 g) (Mouse ear edema model induced by 12-O-tetradecanoylphorbol acetate (TPA))[1]
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Dosage:0.31 μmol/ear
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Administration:Apply to both faces of the right ear; once
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Result:Decreased 17.50% the inflammation of mouse ear edema model.
Chemical Information
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CAS No. 25615-11-6
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Molecular Weight 424.70
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Formula C30H48O
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SMILES
C[C@]12[C@@](CC[C@@]3([H])[C@]2(CC[C@]4([H])[C@@]3(CC[C@@H]4C(C)=C)C)C)([H])[C@@]5([C@@](C(C)(C(CC5)=O)C)([H])CC1)C
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
3-Oxo-hop-22(29)-ene Related Classifications
HY-N10440 Related Classifications
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