Search Result

Results for "

mitogen-activated+protein

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Akt (1) Apoptosis (7) Autophagy (4) Bacterial (2) c-Myc (1) Calcium Channel (1) CaSR (2) CCR (1) CDK (2) Cholinesterase (ChE) (2) COX (2) CXCR (1) DNA/RNA Synthesis (1) Drug Isomer (1) Drug Metabolite (1) Endogenous Metabolite (1) ERK (9) Eukaryotic Initiation Factor (eIF) (1) GCGR (1) Interleukin Related (2) Isotope-Labeled Compounds (2) JNK (4) MAP3K (2) MAP4K (2) MAPKAPK2 (MK2) (4) MDM-2/p53 (1) MEK (7) Microtubule/Tubulin (1) Mitosis (1) mRNA (1) Neurotensin Receptor (1) NF-κB (8) p38 MAPK (26) Phosphatase (5) PKC (1) PROTACs (1) RANKL/RANK (1) Reactive Oxygen Species (ROS) (1) Reference Standards (5) TGF-beta/Smad (3) TGF-β Receptor (2) TNF Receptor (2)
By Research Areas:	Cancer (31) Cardiovascular Disease (2) Endocrinology (1) Infection (6) Inflammation/Immunology (28) Metabolic Disease (6) Neurological Disease (5)
Oligonucleotides:	Phospholipids (1) mRNA (1)

Inhibitors & Agonists

Peptides

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-152860

Darizmetinib HRX-0215	p38 MAPK JNK NF-κB MDM-2/p53	Cancer
Darizmetinib (HRX-0215) is an orally active, potent and selective inhibitor of mitogen-activated protein kinase kinase 4 (MKK4). Darizmetinib leads to enhancement of the MKK7 and JNK1 signaling pathways, thereby activating the transcription factors ATF2 and ELK1, promoting cell proliferation and liver regeneration. Darizmetinib is promising for research of preventing liver failure after extensive oncological liver resections or transplantation of small liver grafts .

HY-119917

Gossypetin 4 Publications Verification	p38 MAPK MEK Bacterial	Infection Cancer
Gossypetin is a hexahydroxylated flavonoid and is a potent mitogen-activated protein kinase kinase (MKK)3 and MKK6 inhibitor with strongly attenuates the MKK3/6-p38 signaling pathway, has various pharmacological activities, including antioxidant, antibacterial and anticancer activities .

HY-N0632

Esculentoside A 2 Publications Verification	COX NF-κB	Inflammation/Immunology
Esculentoside A (EsA), a kind of triterpene saponin isolated from roots of Phytolacca esculenta . Esculentoside A (EsA) possesses anti-inflammatory activity in acute and chronic experimental models , has selective inhibitory activity towards cyclooxygenase-2 (COX-2) . Esculentoside A (EsA) suppresses inflammatory responses in LPS-induced acute lung injury (ALI) through inhibition of the nuclear factor kappa B (NF-ΚB) and mitogen activated protein kinase (MAPK) signaling pathways .

HY-N6246

Asperulosidic Acid	NF-κB ERK	Inflammation/Immunology Cancer
Asperulosidic Acid (ASPA), a bioactive iridoid glycoside, is extracted from the herbs of Hedyotis diffusa Willd. Asperulosidic Acid (ASPA) has anti-tumor, anti-oxidant, and anti-inflammatory activities . ASPA is related to the inhibition of inflammatory cytokines (TNF-α, IL-6) and mediators via suppression of the NF-κB and mitogen-activated protein kinase (MAPK) signaling pathways .

HY-108543

NSC 95397 Maximum Cited Publications 9 Publications Verification	Phosphatase Apoptosis	Cancer
NSC 95397 is a potent, selective Cdc25 dual specificity phosphatase inhibitor (K_i=32 nM (Cdc25A), 96 nM (Cdc25B), 40 nM (Cdc25C); IC₅₀=22.3 nM (human Cdc25A), 56.9 nM (human Cdc25C), 125 nM (Cdc25B)) . NSC 95397 inhibits mitogen-activated protein kinase phosphatase-1 (MKP-1) and suppresses proliferation and induces apoptosis in colon cancer cells through MKP-1 and ERK1/2 pathway .

HY-15300

Skepinone-L 2 Publications Verification CBS3830	p38 MAPK Autophagy	Inflammation/Immunology
Skepinone-L (CBS3830), a chemical probe, is a selective p38 mitogen-activated protein kinase inhibitor.

HY-136409

N-Decanoyl-L-homoserine lactone C10-HSL	Bacterial Reactive Oxygen Species (ROS)	Infection
N-decanoyl-L-homoserine lactone (C10-HSL) is a N-acyl-homoserine lactone (AHL) N-decanoyl-L-homoserine lactone can inhibit primary root growth in Arabidopsis. N-decanoyl-L-homoserine lactone triggers a transient and immediate increase in the concentrations of cytosolic free Ca ²⁺ and reactive oxygen species (ROS), increases the activity of mitogen-activated protein kinase 6 (MPK6), and induces nitric oxide (NO) production in Arabidopsis roots .

HY-139553

Zunsemetinib ATI-450; CDD-450	MAPKAPK2 (MK2)	Inflammation/Immunology
Zunsemetinib (CDD-450) is an orally active and selective p38α mitogen-activated protein kinase-activated protein kinase 2 (MK2) pathway inhibitor. Zunsemetinib can be used for the research of immuno-inflammatory diseases .

HY-139504

Gamcemetinib CC-99677	MAPKAPK2 (MK2)	Inflammation/Immunology
Gamcemetinib (CC-99677) is a potent, covalent, and irreversible inhibitor of the mitogen-activated protein (MAP) kinase-activated protein kinase-2 (MK2) pathway in both biochemical (IC₅₀=156.3 nM) and cell based assays (EC₅₀=89 nM). Gamcemetinib is extracted from patent WO2020236636, compound 1 .

HY-W355700

1-Oleoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine	Drug Metabolite	Infection
1-oleoyl-sn-glycero-3-phosphoethanolamine (LysoPE 18:1) is a lysophosphatidylethanolamine molecule involved in phospholipid metabolism, targeting cell membrane receptors (such as G protein-coupled receptors) to regulate cell signaling pathways. 1-oleoyl-sn-glycero-3-phosphoethanolamine may activate mitogen-activated protein kinase (MAPK) signaling, promote cell migration, regulate inflammatory responses and lipid metabolism, and has both pro-inflammatory and anti-inflammatory activities. 1-oleoyl-sn-glycero-3-phosphoethanolamine is mainly used in the screening of biomarkers for metabolic diseases (such as non-alcoholic fatty liver disease and obesity), as well as the study of the mechanism of lysophospholipids in cell membrane homeostasis and signal transduction .

HY-17397

Strontium Ranelate 2 Publications Verification Distrontium renelate; S12911	CaSR	Metabolic Disease
Strontium Ranelate (S12911) is an antiosteoporotic agent that acts by reducing bone resorption and promoting bone formation, thereby inducing a positive bone balance. Strontium Ranelate can also activate the calcium-sensing receptor (CaSR) in non skeletal cells, resulting in the activation of inositol 1, 4, 5-triphosphate production and mitogen-activated protein kinase signaling .

HY-18758

IN-1130 1 Publications Verification	TGF-β Receptor	Inflammation/Immunology Cancer
IN-1130 is a highly selective transforming growth factor-β type I receptor kinase (ALK5) inhibitor with an IC₅₀ of 5.3 nM for ALK5-mediated Smad3 phosphorylation. IN-1130 inhibits ALK5 phosphorylation of casein (IC₅₀=36 nM) and p38α mitogen-activated protein kinase (IC₅₀=4.3 μM). IN-1130 suppresses renal fibrosis in obstructive nephropathy and blocks breast cancer lung metastasis .

HY-77251

TAK1/MAP4K2 inhibitor 1 1 Publications Verification	MAP4K MAP3K	Cancer
TAK1/MAP4K2 inhibitor 1 is a potent dual TGFβ-activated kinase 1 (TAK1) and mitogen-activated protein kinase kinase kinase kinase 2 (MAP4K2) inhibitor, with IC₅₀s of 41.1 nM and 18.2 nM, respectively.

HY-P10954

Link N peptide	p38 MAPK	Others
Link N peptide is a proteoglycan aggregates activator in the extracellular matrix. Link N peptide can selectively activate the p38 mitogen-activated protein kinase (MAPK) pathway to promote the expression of type I and II collagens in human intervertebral disc cells. Link N peptide is promising for research of intervertebral disc degeneration-related diseases .

HY-P3412

MMI-0100	MAPKAPK2 (MK2)	Inflammation/Immunology
MMI-0100 is a cell-permeant peptide inhibitor of mitogen activated protein kinase activated protein kinase II (MK2). MMI-0100 reduces intimal hyperplasia ex vivo and in vivo. MMI-0100 suppresses IL-6 expression without effect on IL-8 expression. MMI-0100 suppresses fibrotic processes such as vein graft disease .

HY-N4119

Neoeriocitrin	Phosphatase Cholinesterase (ChE) p38 MAPK Apoptosis Autophagy	Neurological Disease Metabolic Disease
Neoeriocitrin is a Naringin (HY-N0153) analogue found in Drynaria Rhizome. Neoeriocitrin induces cells proliferation, differentiation, up-regulates type I collagen, osteocalcin, and key osteogenic markers, and increases ALP activity. Neoeriocitrin increases expression of Runx2, COL I, OCN and Beclin1. Neoeriocitrin inhibits phosphorylation of P38 mitogen-activated protein kinase, reduces acetylcholinesterase (AChE) activity, and increases choline acetyltransferase (ChAT) activity. Neoeriocitrin reduces apoptosis and induces autophagy. Neoeriocitrin can be used for the researches of osteoporosis and Alzheimer's disease .

HY-160469

INY-05-040	Akt PROTACs	Cancer
INY-05-040 is an AKT degrader that can selectively and quickly degrade all three AKT isoforms. INY-05-040 exhibits anti-cancer activity. INY-05-040 can inhibit downstream signaling and cell proliferation in 288 cancer cell lines. INY-05-040 can suppress AKT signaling and induces the stress mitogen-activated protein kinase (MAPK) c-Jun N-terminal kinase (JNK). INY-05-040 is effective for breast cancer lines with a low-baseline activation of stress MAPK pathway. INY-05-040 can be studied for anti-cancer research .

HY-119715

AG-012986	CDK Apoptosis	Inflammation/Immunology Cancer
AG-012986 is a pan-CDK inhibitor with K_i values of 44 nM (CDK1), 9.2 nM (CDK4), 94 nM (CDK2), and IC50 values of 22 nM (CDK5), 4 nM (CDK9). AG-012986 causes apoptosis of T-cells by targeting upstream kinases in the *p38 Mitogen-activated protein* kinase (MAPK*) pathway and impairing cellular survival. AG-012986 induces cell cycle arrest, retinoblastoma protein* hypophosphorylation, and reduces K_i-67 expression. AG-012986 exerts antiproliferative activity in tumor cells, demonstrates antitumor efficacy in human xenograft models, and causes retinal and peripheral neurotoxicity, plus immune cell toxicity. AG-012986 can be used for the research of colon carcinoma, non-small cell lung carcinoma, lung carcinoma, breast carcinoma, ovarian tumor, pancreatic carcinoma, osteosarcoma, lymphoma, leukemia, retinotoxicity .

HY-159846

Luvometinib	MEK	Cancer
Luvometinib is a mitogen-activated protein kinase (MEK) inhibitor with antitumor activity .

HY-Z3832

N-Methylparoxetine	Apoptosis p38 MAPK Autophagy	Cancer
N-Methylparoxetine is a derivative of Paroxetine that induces Apoptosis NSCLC cells by activating mitogen-activated protein kinase ( MAPK). N-Methylparoxetine has antitumor activity .

HY-P10414A

Klotho-derived peptide 1 hydrochloride KP1 (human) hydrochloride	TGF-beta/Smad p38 MAPK	Inflammation/Immunology
Klotho-derived peptide 1 (KP1 human) hydrochloride blocks TGF-β/TGF-β receptor 2 interaction, inhibits TGF-β-induced activation of Smad2/3 and mitogen-activated protein kinase (MAPK), and exhibits anti-fibrotic and kidney protective effects in mouse model .

HY-142042

3-Hydroxy-4-carboxyalkylamidino-5-arylamino-isothiazoles	MEK TGF-beta/Smad	Neurological Disease Inflammation/Immunology Cancer
3-Hydroxy-4-carboxyalkylamidino-5-arylamino-isothiazoles is an inhibitor for *bone morphogenetic protein* 2 (BMP2) with an IC₅₀** of 2.2 μM. 3-Hydroxy-4-carboxyalkylamidino-5-arylamino-isothiazoles is inhibitor for mitogen-activated protein kinase 1 (MEK1). 3-Hydroxy-4-carboxyalkylamidino-5-arylamino-isothiazoles exhibits anti-inflammatory and neuroprotective activity in EAE mouse model .

HY-P10414

Klotho-derived peptide 1 KP1 (human)	TGF-beta/Smad p38 MAPK	Inflammation/Immunology
Klotho-derived peptide 1 (KP1 human) blocks TGF-β/TGF-β receptor 2 interaction, inhibits TGF-β-induced activation of Smad2/3 and mitogen-activated protein kinase (MAPK), and exhibits anti-fibrotic and kidney protective effects in mouse model .

HY-100538A

DTP3 TFA 1 Publications Verification	DNA/RNA Synthesis JNK	Cancer
DTP3 TFA is a potent and selective *GADD45β/MKK7 (growth arrest and DNA-damage-inducible β/mitogen-activated protein* kinase kinase 7)** inhibitor. DTP3 TFA targets an essential, cancer-selective cell-survival module downstream of the NF-κB pathway .

HY-N12188

Stigmasta-3,5-dien-7-one	NF-κB TNF Receptor Interleukin Related p38 MAPK	Inflammation/Immunology
Stigmasta-3,5-dien-7-one is a steroid compound that can be isolated from Harrisonia abyssinica. Stigmasta-3,5-dien-7-one blocks the NF-κB signaling pathway via down-regulation of phospho-p38 mitogen-activated protein kinase and phosphorylation and degradation of inhibitor of NF-κB α. Stigmasta-3,5-dien-7-one reduces LPS (HY-D1056)-induced nitric oxide, PGE₂, and pro-inflammatory cytokine levels in macrophages. Stigmasta-3,5-dien-7-one can be used for inflammation diseases .

HY-145025

ERK1/2 inhibitor 3	ERK	Inflammation/Immunology Cancer
ERK1/2 inhibitor 3 is a potent inhibitor of ERK1/2. Mitogen-activated protein kinase (MAPK) plays an extremely important role in the signal transduction pathway, and extracellular signal regulated kinase (ERK) is a member of the MAPK family. ERK1/2 inhibitor 3 has the potential for the research or prevention of cancer, inflammation or other proliferative diseases (extracted from patent WO2021218912A1, compound 1) .

HY-120505

ITZ-1	ERK p38 MAPK	Inflammation/Immunology
ITZ-1 is an orally active and selective extracellular signal-regulated kinase (ERK)-mitogen-activated protein kinase (MAPK) pathway inhibitor with an IC₅₀ of 0.51 μM for inhibiting interleukin-1β (IL-1β)-induced matrix metalloproteinase-13 (MMP-13) production. ITZ-1 reduces MMP-13 expression and suppresses nitric oxide (NO)-induced chondrocyte apoptosi. ITZ-1 is promising for research of osteoarticular diseases .

HY-139553A

(R)-Zunsemetinib (R)-ATI-450; (R)-CDD-450	Drug Isomer	Inflammation/Immunology
(R)-Zunsemetinib is the isomer of Zunsemetinib (HY-139553), and can be used as an experimental control. Zunsemetinib (CDD-450) is an orally active and selective p38α mitogen-activated protein kinase-activated protein kinase 2 (MK2) pathway inhibitor. Zunsemetinib can be used for the research of immuno-inflammatory diseases .

HY-145026

ERK1/2 inhibitor 4	ERK	Inflammation/Immunology Cancer
ERK1/2 inhibitor 5 is a potent inhibitor of ERK1/2. Mitogen-activated protein kinase (MAPK) plays an extremely important role in the signal transduction pathway, and extracellular signal regulated kinase (ERK) is a member of the MAPK family. ERK1/2 inhibitor 5 has the potential for the research or prevention of cancer, inflammation or other proliferative diseases (extracted from patent WO2020238776A1) .

HY-145027

ERK1/2 inhibitor 5	ERK	Cancer
ERK1/2 inhibitor 5 is a potent inhibitor of ERK1/2. Mitogen-activated protein kinase (MAPK) plays an extremely important role in the signal transduction pathway, and extracellular signal regulated kinase (ERK) is a member of the MAPK family. ERK1/2 inhibitor 5 has the potential for the research or prevention of cancer, inflammation or other proliferative diseases (extracted from patent WO2020238776A1) .

HY-N0632R

Esculentoside A (Standard)	Reference Standards COX NF-κB	Inflammation/Immunology
Esculentoside A (Standard) is the analytical standard of Esculentoside A. This product is intended for research and analytical applications. Esculentoside A (EsA), a kind of triterpene saponin isolated from roots of Phytolacca esculenta . Esculentoside A (EsA) possesses anti-inflammatory activity in acute and chronic experimental models , has selective inhibitory activity towards cyclooxygenase-2 (COX-2) . Esculentoside A (EsA) suppresses inflammatory responses in LPS-induced acute lung injury (ALI) through inhibition of the nuclear factor kappa B (NF-ΚB) and mitogen activated protein kinase (MAPK) signaling pathways .

HY-P11405

[D-Arg1,D-Trp5,7,9,Leu11]-Substance P	Neurotensin Receptor	Neurological Disease Cancer
[D-Arg1, D-Trp5, 7, 9, Leu11]-Substance P is a potent inhibitor of cell growth in small cell lung cancer (SCLC). [D-Arg1, D-Trp5, 7, 9, Leu11]-Substance P is also a neuropeptide antagonist, capable of blocking colony formation stimulated by various neuropeptides (including vasopressin and bradykinin). [D-Arg1, D-Trp5, 7, 9, Leu11]-Substance P inhibits the mobilization of Ca ²⁺ and the activation of mitogen-activated protein kinases induced by vasopressin or bradykinin. [D-Arg1, D-Trp5, 7, 9, Leu11]-Substance P inhibits the growth of H-69 xenograft tumors in nude mice .

HY-N12898

(Z)-Tetradec-7-en-1-ol	p38 MAPK	Others
(Z)-Tetradec-7-en-1-ol is an activator for mitogen-activated protein kinase (MAP kinase) .

HY-161293

p38-α MAPK-IN-6	p38 MAPK	Cancer
p38-α MAPK-IN-6 (compound 3a) is a p38α mitogen-activated protein kinase inhibitor .

HY-132878

FgGpmk1-IN-1	p38 MAPK	Infection
FgGpmk1-IN-1 is a novel *fusarium graminearum mitogen-activated protein* kinase (FgGpmk1) inhibitor with an EC₅₀** value of 3.46 μg/mL.

HY-14974

R 1487	p38 MAPK	Inflammation/Immunology
R 1487 is an orally active and highly selective *p38α mitogen-activated protein* kinase inhibitor**. R 1487 can be used in the study of rheumatoid arthritis .

HY-E70843

*MAP2K1 P124L Recombinant Human Active Protein* Kinase**	MEK	Cancer
MAP2K1 encodes mitogen-activated protein kinase 1 (MEK1), which is a key component in the RAS-mitogen-activated protein kinase kinase (RAS/MAPK) signal transduction pathway. MAP2K1 P124L mutation is a mild mutation. MAP2K1 P124L Recombinant Human Active Protein Kinase is a recombinant MAP2K1 P124L protein that can be used to study MAP2K1 P124L-related functions .

HY-100278

AKP-001	p38 MAPK	Inflammation/Immunology
AKP-001 is an inhibitor of p38 mitogen-activated protein kinase (p38 MAPK). AKP-001 can inhibit the production of inflammatory cytokines and can be used for research in rheumatoid arthritis and inflammatory bowel disease .

HY-169513

MK2-IN-7	MAPKAPK2 (MK2)	Inflammation/Immunology Cancer
MK2-IN-7 (Compound 144) is a mitogen activated protein kinase-activated protein kinase-2 (MK2) inhibitor. MK2-IN-7 is promising for research of inflammatory diseases, autoimmune diseases and cancer .

HY-10508

(R)-PD 0325901CL	MEK	Cancer
(R)-PD 0325901CL is an isomer of PD 0325901CL. PD 0325901CL is a selective inhibitor of mitogen-activated protein kinase kinase (MEK) involved in cancer research. PD 0325901CL inhibits the growth of cancer cells in vitro and in vivo .

HY-P3894

P34cdc2 Kinase Fragment	Microtubule/Tubulin Mitosis	Others
P34cdc2 Kinase Fragment is associated with the completion of DNA replication in yeast mitosis. P34cdc2 Kinase can phosphorylate mitogen-activated protein 2 (MAP2) to regulate microtubules polymerization in Xenopus oocytes meiosis .

HY-175431

p38 MAPK-IN-8	p38 MAPK	Inflammation/Immunology Cancer
p38 MAPK-IN-8 (Compound 8) is an orally active, potent and selective p38 mitogen-activated protein kinase (p38 MAPK) inhibitor. p38 MAPK-IN-8 is promising for research of inflammatory responses, autoimmune diseases, and cancer .

HY-175432

p38 MAPK-IN-9	p38 MAPK	Inflammation/Immunology
p38 MAPK-IN-9 (Compound 15) is an orally active and highly selective p38α mitogen-activated protein kinase (p38 MAPK) inhibitor with an IC₅₀ value of 9.6 nM. p38 MAPK-IN-9 is promising for research of inflammatory diseases such as rheumatoid arthritis, septic shock, and chronic obstructive pulmonary disease (COPD) .

HY-120485

Raxofelast IRFI-016	p38 MAPK ERK PKC	Cardiovascular Disease
Raxofelast (IRFI-016) is an antioxidant agent in various models of ischemia-reperfusion injury. Raxofelast has antiproliferative activity in H₂O₂-stimulated rat aortic smooth muscle cells. Raxofelast attenuates the activation of mitogen-activating protein kinase (MAPK), ERK kinase 1, 2 (MEK1,2) and protein kinase C (PKC) without affecting Ras expression .

HY-N6246R

Asperulosidic Acid (Standard)	Reference Standards NF-κB ERK	Inflammation/Immunology Cancer
Asperulosidic Acid (Standard) is the analytical standard of Asperulosidic Acid. This product is intended for research and analytical applications. Asperulosidic Acid (ASPA), a bioactive iridoid glycoside, is extracted from the herbs of Hedyotis diffusa Willd. Asperulosidic Acid (ASPA) has anti-tumor, anti-oxidant, and anti-inflammatory activities . ASPA is related to the inhibition of inflammatory cytokines (TNF-α, IL-6) and mediators via suppression of the NF-κB and mitogen-activated protein kinase (MAPK) signaling pathways .

HY-148552

Anti-inflammatory agent 35 1 Publications Verification	p38 MAPK ERK NF-κB Interleukin Related TNF Receptor	Inflammation/Immunology
Anti-inflammatory agent 35 (compound 5a27) is an orally active curcumin analogue with anti-inflammatory activity. Anti-inflammatory agent 35 blocks mitogen-activated protein kinase (MAPK) signaling and p65 nuclear translocation of NF-kB. Anti-inflammatory agent 35 also inhibits yellow neutrophil infiltration and pro-inflammatory cytokine production. Anti-inflammatory agent 35 significantly attenuates lipopolysaccharide (LPS)-induced acute lung injury (ALI) in vivo .

HY-168090

Anti-osteoporosis agent-11	p38 MAPK NF-κB RANKL/RANK	Endocrinology
Anti-osteoporosis agent-11 (compound 3k) is an anti-osteoporosis compound targeting osteoclasts. Anti-osteoporosis agent-11 has the most significant inhibitory effect on osteoclast differentiation, with an IC₅₀ value of 0.36 μM. In addition, Anti-osteoporosis agent-11 inhibits osteoclast formation, bone resorption, and the expression of osteoclast-specific genes by blocking rankl-induced mitogen-activated protein kinase (MAPK) and NF-κB signaling pathways .

HY-E70759

*MKK6 SDTD Recombinant Human Active Protein* Kinase**	p38 MAPK	Cancer
The mitogen-activated protein kinase kinase 6 (MKK6) is one of the upstream activators of p38 MAPK. MKK6 activates myocardial cell NF-κB and inhibits apoptosis in a p38 MAPK-dependent manner. MKK6 SDTD is a mutant of MKK6. MKK6 SDTD Recombinant Human Active Protein Kinase is a recombinant MKK6 SDTD protein that can be used to study MKK6 SDTD-related functions .

HY-145028

ERK1/2 inhibitor 6	ERK	Inflammation/Immunology Cancer
ERK1/2 inhibitor 6 is a potent inhibitor of ERK1/2. Mitogen-activated protein kinase (MAPK) plays an extremely important role in the signal transduction pathway, and extracellular signal regulated kinase (ERK) is a member of the MAPK family. ERK1/2 inhibitor 6 has the potential for the research or prevention of cancer, inflammation or other proliferative diseases (extracted from patent WO2021063335A1, compound 1) .

HY-17397R

Strontium Ranelate (Standard) Distrontium renelate (Standard); S12911 (Standard)	Reference Standards CaSR	Metabolic Disease
Strontium Ranelate (Standard) is the analytical standard of Strontium Ranelate. This product is intended for research and analytical applications. Strontium Ranelate (S12911) is an antiosteoporotic agent that acts by reducing bone resorption and promoting bone formation, thereby inducing a positive bone balance. Strontium Ranelate can also activate the calcium-sensing receptor (CaSR) in non skeletal cells, resulting in the activation of inositol 1, 4, 5-triphosphate production and mitogen-activated protein kinase signaling .

Cat. No.	Product Name	Target	Research Area

HY-P10954

Link N peptide	p38 MAPK	Others
Link N peptide is a proteoglycan aggregates activator in the extracellular matrix. Link N peptide can selectively activate the p38 mitogen-activated protein kinase (MAPK) pathway to promote the expression of type I and II collagens in human intervertebral disc cells. Link N peptide is promising for research of intervertebral disc degeneration-related diseases .

HY-P3412

MMI-0100	MAPKAPK2 (MK2)	Inflammation/Immunology
MMI-0100 is a cell-permeant peptide inhibitor of mitogen activated protein kinase activated protein kinase II (MK2). MMI-0100 reduces intimal hyperplasia ex vivo and in vivo. MMI-0100 suppresses IL-6 expression without effect on IL-8 expression. MMI-0100 suppresses fibrotic processes such as vein graft disease .

HY-P10414A

Klotho-derived peptide 1 hydrochloride KP1 (human) hydrochloride	TGF-beta/Smad p38 MAPK	Inflammation/Immunology
Klotho-derived peptide 1 (KP1 human) hydrochloride blocks TGF-β/TGF-β receptor 2 interaction, inhibits TGF-β-induced activation of Smad2/3 and mitogen-activated protein kinase (MAPK), and exhibits anti-fibrotic and kidney protective effects in mouse model .

HY-P10414

Klotho-derived peptide 1 KP1 (human)	TGF-beta/Smad p38 MAPK	Inflammation/Immunology
Klotho-derived peptide 1 (KP1 human) blocks TGF-β/TGF-β receptor 2 interaction, inhibits TGF-β-induced activation of Smad2/3 and mitogen-activated protein kinase (MAPK), and exhibits anti-fibrotic and kidney protective effects in mouse model .

HY-100538A

DTP3 TFA 1 Publications Verification	DNA/RNA Synthesis JNK	Cancer
DTP3 TFA is a potent and selective *GADD45β/MKK7 (growth arrest and DNA-damage-inducible β/mitogen-activated protein* kinase kinase 7)** inhibitor. DTP3 TFA targets an essential, cancer-selective cell-survival module downstream of the NF-κB pathway .

HY-P11405

[D-Arg1,D-Trp5,7,9,Leu11]-Substance P	Neurotensin Receptor	Neurological Disease Cancer
[D-Arg1, D-Trp5, 7, 9, Leu11]-Substance P is a potent inhibitor of cell growth in small cell lung cancer (SCLC). [D-Arg1, D-Trp5, 7, 9, Leu11]-Substance P is also a neuropeptide antagonist, capable of blocking colony formation stimulated by various neuropeptides (including vasopressin and bradykinin). [D-Arg1, D-Trp5, 7, 9, Leu11]-Substance P inhibits the mobilization of Ca ²⁺ and the activation of mitogen-activated protein kinases induced by vasopressin or bradykinin. [D-Arg1, D-Trp5, 7, 9, Leu11]-Substance P inhibits the growth of H-69 xenograft tumors in nude mice .

HY-P3894

P34cdc2 Kinase Fragment	Microtubule/Tubulin Mitosis	Others
P34cdc2 Kinase Fragment is associated with the completion of DNA replication in yeast mitosis. P34cdc2 Kinase can phosphorylate mitogen-activated protein 2 (MAP2) to regulate microtubules polymerization in Xenopus oocytes meiosis .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-119917

Gossypetin 4 Publications Verification	Infection Flavonols Flavonoids Classification of Application Fields Rhodiola rosea Linn. Crassulaceae Phenols Polyphenols Plants Disease Research Fields Source Classification	p38 MAPK MEK Bacterial
Gossypetin is a hexahydroxylated flavonoid and is a potent mitogen-activated protein kinase kinase (MKK)3 and MKK6 inhibitor with strongly attenuates the MKK3/6-p38 signaling pathway, has various pharmacological activities, including antioxidant, antibacterial and anticancer activities .

HY-N0632

Esculentoside A 2 Publications Verification	Triterpenes Classification of Application Fields Terpenoids Phytolacca acinosa Roxb. Plants Inflammation/Immunology Disease Research Fields Phytolaccaceae Source Classification	COX NF-κB
Esculentoside A (EsA), a kind of triterpene saponin isolated from roots of Phytolacca esculenta . Esculentoside A (EsA) possesses anti-inflammatory activity in acute and chronic experimental models , has selective inhibitory activity towards cyclooxygenase-2 (COX-2) . Esculentoside A (EsA) suppresses inflammatory responses in LPS-induced acute lung injury (ALI) through inhibition of the nuclear factor kappa B (NF-ΚB) and mitogen activated protein kinase (MAPK) signaling pathways .

HY-N6246

Asperulosidic Acid	Iridoids Classification of Application Fields Terpenoids Rubiaceae Plants Morinda officinalis How Inflammation/Immunology Disease Research Fields Source Classification	NF-κB ERK
Asperulosidic Acid (ASPA), a bioactive iridoid glycoside, is extracted from the herbs of Hedyotis diffusa Willd. Asperulosidic Acid (ASPA) has anti-tumor, anti-oxidant, and anti-inflammatory activities . ASPA is related to the inhibition of inflammatory cytokines (TNF-α, IL-6) and mediators via suppression of the NF-κB and mitogen-activated protein kinase (MAPK) signaling pathways .

HY-136409

N-Decanoyl-L-homoserine lactone C10-HSL	Microorganisms Source Classification	Bacterial Reactive Oxygen Species (ROS)
N-decanoyl-L-homoserine lactone (C10-HSL) is a N-acyl-homoserine lactone (AHL) N-decanoyl-L-homoserine lactone can inhibit primary root growth in Arabidopsis. N-decanoyl-L-homoserine lactone triggers a transient and immediate increase in the concentrations of cytosolic free Ca ²⁺ and reactive oxygen species (ROS), increases the activity of mitogen-activated protein kinase 6 (MPK6), and induces nitric oxide (NO) production in Arabidopsis roots .

HY-N4119

Neoeriocitrin	Structural Classification Flavonoids other families Flavonones Phenols Polyphenols Plants Source Classification	Phosphatase Cholinesterase (ChE) p38 MAPK Apoptosis Autophagy
Neoeriocitrin is a Naringin (HY-N0153) analogue found in Drynaria Rhizome. Neoeriocitrin induces cells proliferation, differentiation, up-regulates type I collagen, osteocalcin, and key osteogenic markers, and increases ALP activity. Neoeriocitrin increases expression of Runx2, COL I, OCN and Beclin1. Neoeriocitrin inhibits phosphorylation of P38 mitogen-activated protein kinase, reduces acetylcholinesterase (AChE) activity, and increases choline acetyltransferase (ChAT) activity. Neoeriocitrin reduces apoptosis and induces autophagy. Neoeriocitrin can be used for the researches of osteoporosis and Alzheimer's disease .

HY-N12188

Stigmasta-3,5-dien-7-one	Structural Classification Harrisonia abyssinica Oliv. Cardiacglycosides Rutaceae Plants Steroids Source Classification	NF-κB TNF Receptor Interleukin Related p38 MAPK
Stigmasta-3,5-dien-7-one is a steroid compound that can be isolated from Harrisonia abyssinica. Stigmasta-3,5-dien-7-one blocks the NF-κB signaling pathway via down-regulation of phospho-p38 mitogen-activated protein kinase and phosphorylation and degradation of inhibitor of NF-κB α. Stigmasta-3,5-dien-7-one reduces LPS (HY-D1056)-induced nitric oxide, PGE₂, and pro-inflammatory cytokine levels in macrophages. Stigmasta-3,5-dien-7-one can be used for inflammation diseases .

HY-N0632R

Esculentoside A (Standard)	Triterpenes Structural Classification Terpenoids Phytolacca acinosa Roxb. Plants Phytolaccaceae Source Classification	Reference Standards COX NF-κB
Esculentoside A (Standard) is the analytical standard of Esculentoside A. This product is intended for research and analytical applications. Esculentoside A (EsA), a kind of triterpene saponin isolated from roots of Phytolacca esculenta . Esculentoside A (EsA) possesses anti-inflammatory activity in acute and chronic experimental models , has selective inhibitory activity towards cyclooxygenase-2 (COX-2) . Esculentoside A (EsA) suppresses inflammatory responses in LPS-induced acute lung injury (ALI) through inhibition of the nuclear factor kappa B (NF-ΚB) and mitogen activated protein kinase (MAPK) signaling pathways .

HY-N12898

(Z)-Tetradec-7-en-1-ol	Natural Products Animals Source Classification	p38 MAPK
(Z)-Tetradec-7-en-1-ol is an activator for mitogen-activated protein kinase (MAP kinase) .

HY-N6246R

Asperulosidic Acid (Standard)	Structural Classification Iridoids Terpenoids Rubiaceae Plants Morinda officinalis How Source Classification	Reference Standards NF-κB ERK
Asperulosidic Acid (Standard) is the analytical standard of Asperulosidic Acid. This product is intended for research and analytical applications. Asperulosidic Acid (ASPA), a bioactive iridoid glycoside, is extracted from the herbs of Hedyotis diffusa Willd. Asperulosidic Acid (ASPA) has anti-tumor, anti-oxidant, and anti-inflammatory activities . ASPA is related to the inhibition of inflammatory cytokines (TNF-α, IL-6) and mediators via suppression of the NF-κB and mitogen-activated protein kinase (MAPK) signaling pathways .

HY-N11723

Catenarin Katenarin	Quinones Microorganisms Anthraquinones Source Classification	CCR CXCR p38 MAPK JNK Calcium Channel
Catenarin, an anthraquinone compound, inhibits CCR5- and CXCR4-mediated chemotaxis. Catenarin reduces the phosphorylation of mitogen-activated protein kinases (p38 and JNK) and their upstream kinases (MKK6 and MKK7), and calcium mobilization. Catenarin shows anti-inflammatory effect and suppresses leukocyte migration in the diabetes. Catenarin exhibits significant inhibitory effects against Gram-positive bacteria. Catenarin prevents type 1 diabetes (T1D) in nonobese diabetic mice ^[1][2].

HY-N4119R

Neoeriocitrin (Standard)	Structural Classification Flavonoids other families Flavonones Phenols Polyphenols Plants Source Classification	Reference Standards Phosphatase Cholinesterase (ChE) p38 MAPK Apoptosis Autophagy
Neoeriocitrin (Standard) is the analytical standard of Neoeriocitrin (HY-N4119). This product is intended for research and analytical applications. Neoeriocitrin is a Naringin (HY-N0153) analogue found in Drynaria Rhizome. Neoeriocitrin induces cells proliferation, differentiation, up-regulates type I collagen, osteocalcin, and key osteogenic markers, and increases ALP activity. Neoeriocitrin increases expression of Runx2, COL I, OCN and Beclin1. Neoeriocitrin inhibits phosphorylation of P38 mitogen-activated protein kinase, reduces acetylcholinesterase (AChE) activity, and increases choline acetyltransferase (ChAT) activity. Neoeriocitrin reduces apoptosis and induces autophagy. Neoeriocitrin can be used for the researches of osteoporosis and Alzheimer's disease .

Species:	Human (59) Mouse (2)
Tag:	His (34) Strep (1) Tag Free (9) Avi (2) GST (38) Flag (2)
Source:	Sf9 insect cells (2) P. pastoris (1) Sf9 insect cells (42) E. coli (16)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P705606

	*MLK2 Protein, Human (Active, Biotinylated, sf9, His, Avi)* mitogen-activated protein kinase kinase kinase 10, MAP3K10, MST	Human	Sf9 insect cells

HY-P705995

	*MLK1 Protein, Human (Active, sf9, His-GST)* mitogen-activated protein kinase kinase kinase 9, MAP3K9, PRKE1	Human	Sf9 insect cells

HY-P706079

	*P38β Protein, Human (Active, sf9, His-GST)* mitogen-activated protein kinase 11; mitogen-activated protein kinase p38 beta; MAP kinase p38 beta; p38b; Stress-activated protein kinase 2b; SAPK2b; p38-2; PRKM11; SAPK2; SAPK2B	Human	Sf9 insect cells

HY-P704002

	*ASK3 Protein, Human (Active, sf9, GST)* ASK3; MAP3K15; mitogen-activated protein kinase kinase kinase 15	Human	Sf9 insect cells
	ASK3 Protein, Human (Active, sf9, GST) is the recombinant human-derived ASK3 protein, expressed by Sf9 insect cells, with N-GST tag.

HY-P705605

	*MLK1 Protein, Human (Active, Biotinylated, sf9, His, Avi)* mitogen-activated protein kinase kinase kinase 9, MAP3K9, PRKE1	Human	Sf9 insect cells

HY-P701730

	*P38β Protein, Human (Inactive, sf9)* MAPK11; mitogen-activated protein kinase 11; MAP kinase 11; MAPK 11; mitogen-activated protein kinase p38 beta; MAP kinase p38 beta; p38b; Stress-activated protein kinase 2b; SAPK2b; p38-2	Human	Sf9 insect cells
	The P38β protein is an important serine/threonine kinase in the MAP kinase pathway that responds to extracellular stimuli, including proinflammatory cytokines and physical stress. As part of the p38 MAPK family, P38β directly activates transcription factors that phosphorylate many proteins, including RPS6KA5/MSK1 and RPS6KA4/MSK2. P38β Protein, Human (sf9) is the recombinant human-derived P38β protein, expressed by sf9 insect cells , with tag free.

HY-P701731

	*P38β Protein, Human (Inactive, sf9, GST)* MAPK11; mitogen-activated protein kinase 11; MAP kinase 11; MAPK 11; mitogen-activated protein kinase p38 beta; MAP kinase p38 beta; p38b; Stress-activated protein kinase 2b; SAPK2b; p38-2	Human	Sf9 insect cells
	The P38β protein is an important serine/threonine kinase in the MAP kinase pathway that responds to extracellular stimuli, including proinflammatory cytokines and physical stress. As part of the p38 MAPK family, P38β directly activates transcription factors that phosphorylate many proteins, including RPS6KA5/MSK1 and RPS6KA4/MSK2. P38β Protein, Human (sf9, GST) is the recombinant human-derived P38β protein, expressed by sf9 insect cells , with N-GST labeled tag.

HY-P705668

	*P38β Protein, Human (Active, Phosphorylated, Sf9, GST)* MAPK11; mitogen-activated protein kinase 11; MAP kinase 11; MAPK 11; mitogen-activated protein kinase p38 beta; MAP kinase p38 beta; p38b; Stress-activated protein kinase 2b; SAPK2b; p38-2	Human	Sf9 insect cells
	The P38β protein is an important serine/threonine kinase in the MAP kinase pathway that responds to extracellular stimuli, including proinflammatory cytokines and physical stress. As part of the p38 MAPK family, P38β directly activates transcription factors that phosphorylate many proteins, including RPS6KA5/MSK1 and RPS6KA4/MSK2. P38β Protein, Human (Active, Phosphorylated, Sf9, GST) is the recombinant human-derived P38β protein, expressed by sf9 insect cells , with N-GST labeled tag.

HY-P73848

	*JNK1 Protein, Human (Inactive, sf9, GST)* 1 Publications Verification mitogen-activated protein kinase 8; MAPK 8; JNK-46; JNK1; PRKM8	Human	Sf9 insect cells
	JNK1 is a multifunctional serine/threonine protein kinase that complexly regulates multiple cellular processes, including cell proliferation, apoptosis, and differentiation. JNK1 is activated by MAP2K4/MKK4 and MAP2K7/MKK7, phosphorylates AP-1 components, and affects transcriptional activity. JNK1 Protein, Human (sf9, GST) is the recombinant human-derived JNK1 protein, expressed by Sf9 insect cells , with N-GST labeled tag.

HY-P703054

	*ASK3 Protein, Human (588a.a, sf9, GST)* ASK3; MAP3K15; mitogen-activated protein kinase kinase kinase 15;	Human	Sf9 insect cells
	ASK3 Protein, Human (588a.a, sf9, GST) is the recombinant human-derived ASK3, expressed by Sf9 insect cells, with GST labeled tag.

HY-P70931

	*MAPKSP1 Protein, Human (His)* Ragulator Complex Protein LAMTOR3; Late Endosomal/Lysosomal Adaptor and MAPK and MTOR Activator 3; MEK-Binding Partner 1; Mp1; mitogen-Activated Protein Kinase Kinase 1-Interacting Protein 1; mitogen-Activated Protein Kinase Scaffold Protein 1; LAMTOR3; MAP2K1IP	Human	E. coli
	The MAPKSP1 protein, also known as porphobilinogen deaminase (HMBS), is crucial in the heme biosynthetic pathway and catalyzes the sequential polymerization of four porphobilinogen molecules to form hydroxymethyl bixane. The process begins with the assembly of the dipyrromethane cofactor of porphobilinogen or preuroporphyrinogen. MAPKSP1 Protein, Human (His) is the recombinant human-derived MAPKSP1 protein, expressed by E. coli , with N-6*His labeled tag.

HY-P700593

	*MAP3K1 Protein, Mouse (His)* MEKK; MEKK1; SRXY6; MEKK 1; MAPKKK1; MAP/ERK kinase kinase 1; MAPK/ERK kinase kinase 1; MEK kinase 1; mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase; mitogen-activated protein kinase kinase kinase 1	Mouse	E. coli
	MAP3K1 is a key component of the protein kinase signal transduction cascade and plays a crucial role in cell signaling pathways.Through its kinase activity, MAP3K1 coordinates the activation of the ERK and JNK kinase pathways by phosphorylating MAP2K1 and MAP2K4.MAP3K1 Protein, Mouse (His) is the recombinant mouse-derived MAP3K1 protein, expressed by E.coli , with N-6*His labeled tag.

HY-P703924

	*p38 gamma/MAPK12 Protein, Human (sf9, GST)* mitogen-activated protein kinase 12; MAP kinase 12; MAPK 12; Extracellular signal-regulated kinase 6 (ERK-6); mitogen-activated protein kinase p38 gamma (MAP kinase p38 gamma); Stress-activated protein kinase 3	Human	Sf9 insect cells
	The p38 gamma/MAPK12 protein is an important serine/threonine kinase in the MAP kinase pathway and can respond to extracellular stimuli such as pro-inflammatory cytokines or stress. p38 MAPK activates transcription factors such as ELK1 and ATF2, each of which phosphorylates approximately 200 to 300 substrates. p38 gamma/MAPK12 Protein, Human (Active, sf9, GST) is the recombinant human-derived p38 gamma/MAPK12 protein, expressed by Sf9 insect cells, with N-GST labeled tag.

HY-P74755

	*MEK2 Protein, Human (Active, sf9, GST)* Dual specificity mitogen-activated protein kinase kinase 2; MAPKK 2; MEK 2	Human	Sf9 insect cells
	The MEK2 protein phosphorylates threonine and tyrosine residues in a Thr-Glu-Tyr sequence of MAP kinases. It activates ERK1 and ERK2 MAP kinases and BRAF through a KSR1 or KSR2-dependent mechanism. By binding to KSR1 or KSR2, it enables dimerization and activation of BRAF by releasing inhibitory intramolecular interactions (PubMed:29433126). MEK2 Protein, Human (sf9, GST) is the recombinant human-derived MEK2 protein, expressed by Sf9 insect cells , with N-GST labeled tag.

HY-P73334

	*p38 delta/MAPK13 Protein, Human (Active, sf9, GST)* mitogen-activated protein kinase 13; MAPK 13; PRKM13; SAPK4	Human	Sf9 insect cells
	The p38 delta/MAPK13 protein is an important serine/threonine kinase in the MAP kinase pathway. It coordinates cellular responses to stimuli such as cytokines or stress and directly activates the transcription factors ELK1 and ATF2. In this cascade, p38 MAPK (including MAPK13) each phosphorylates approximately 200 to 300 substrates. p38 delta/MAPK13 Protein, Human (sf9, GST) is the recombinant human-derived p38 delta/MAPK13 protein, expressed by Sf9 insect cells , with N-GST labeled tag.

HY-P75223

	*MAPK1/ERK2 Protein, Human (Active, sf9, His)* 1 Publications Verification mitogen-activated protein kinase 1; MAPK 1; ERT1; ERK-2; p42-MAPK	Human	Sf9 insect cells
	ERK2 Protein, a key component of the MAPK/ERK cascade, regulates diverse cellular processes such as transcription, translation, mitosis, apoptosis, endosomal dynamics, and Golgi apparatus fragmentation. Through phosphorylation, it modulates substrates including transcription factors, cytoskeletal elements, apoptosis regulators, translation regulators, protein kinases, and phosphatases. MAPK1/ERK2 Protein, Human (sf9, His) is the recombinant human-derived ERK2 protein, expressed by Sf9 insect cells , with C-His labeled tag.

HY-P76532

	*p38 gamma/MAPK12 Protein, Human (sf9)* mitogen-activated protein kinase 12; Extracellular signal-regulated kinase 6; ERK-6; SAPK3	Human	Sf9 insect cells
	The p38 gamma/MAPK12 protein is an important serine/threonine kinase in the MAP kinase pathway and can respond to extracellular stimuli such as pro-inflammatory cytokines or stress. p38 MAPK activates transcription factors such as ELK1 and ATF2, each of which phosphorylates approximately 200 to 300 substrates. p38 gamma/MAPK12 Protein, Human (sf9) is the recombinant human-derived p38 gamma/MAPK12 protein, expressed by Sf9 insect cells, with tag free.

HY-P75921

	*MAP3K8/TPL-2 Protein, Human (sf9, GST)* mitogen-activated protein kinase kinase kinase 8; TPL-2; MAP3K8; COT; ESTF	Human	Sf9 insect cells
	MAP3K8/TPL-2 is critical for LPS-induced, TLR4-mediated activation of MAPK/ERK, leading to TNF production by macrophages. It regulates T cell differentiation, IFNG expression, and host resistance to bacterial infections by negatively regulating type I interferon production. MAP3K8/TPL-2 Protein, Human (sf9, GST) is the recombinant human-derived MAP3K8/TPL-2 protein, expressed by Sf9 insect cells , with N-GST labeled tag.

HY-P73335

	*p38 alpha/MAPK14 Protein, Human (Active, sf9, His)* mitogen-activated protein kinase 14; MAPK 14; CSBP; MXI2; SAPK2A	Human	Sf9 insect cells
	The p38 α/MAPK14 protein is an important serine/threonine kinase in the MAP kinase pathway. It can respond to stimuli such as cytokines or stress and directly activate transcription factors. In this cascade, p38 MAPK each phosphorylates approximately 200 to 300 substrates, including the downstream kinases RPS6KA5/MSK1 and RPS6KA4/MSK2, which are critical for immediate early gene induction. p38 alpha/MAPK14 Protein, Human (Activated, sf9, His) is the recombinant human-derived p38 alpha/MAPK14 protein, expressed by Sf9 insect cells , with N-His labeled tag.

HY-P74746

	*MKK6 Protein, Human (sf9)* Dual specificity mitogen-activated protein kinase kinase 6; MAPKK 6; MEK 6; SAPKK3; MAP2K6	Human	Sf9 insect cells
	The MKK6 protein is a dual-specificity kinase involved in the MAP kinase pathway. MKK6 Protein, Human (sf9) is the recombinant human-derived MKK6 protein, expressed by Sf9 insect cells, with tag free and additional two amino acids (Gly & Pro) at the N-terminus.

HY-P76533

	*p38 gamma/MAPK12 Protein, Human (sf9, His-GST)* mitogen-activated protein kinase 12; Extracellular signal-regulated kinase 6; ERK-6; SAPK3	Human	Sf9 insect cells
	The p38 gamma/MAPK12 protein is an important serine/threonine kinase in the MAP kinase pathway and can respond to extracellular stimuli such as pro-inflammatory cytokines or stress. p38 MAPK activates transcription factors such as ELK1 and ATF2, each of which phosphorylates approximately 200 to 300 substrates. p38 gamma/MAPK12 Protein, Human (sf9, His-GST) is the recombinant human-derived p38 gamma/MAPK12 protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag.

HY-P76946

	*MAP4K2 Protein, Human (sf9, His-GST)* mitogen-activated protein kinase kinase kinase kinase 2; GC kinase; MEKKK 2; GCK; RAB8IP	Human	Sf9 insect cells
	MAP4K2 is a serine/threonine protein kinase and an important component of the MAP kinase signal transduction pathway. It acts as a MAPK kinase kinase (MAP4K), activating the stress-activated protein kinase/c-Jun N-terminal kinase (SAP/JNK) pathway and, to a lesser extent, the p38 MAPKs pathway. MAP4K2 Protein, Human (sf9, His-GST) is the recombinant human-derived MAP4K2 protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag.

HY-P706067

	*MLK2 Protein, Human (Active, sf9, His-GST)* mitogen-activated protein kinase kinase kinase 10; Mixed lineage kinase 2; Protein kinase MST; MLK2; MST	Human	Sf9 insect cells

HY-P73825

	*MEK1 Protein, Mouse (Inactive, sf9, His-GST)* Dual specificity mitogen-activated protein kinase kinase 1; MAPKK 1; MEK 1; Map2k1	Mouse	Sf9 insect cells
	The MEK1 protein is a dual-specificity kinase that plays a crucial role in the MAP kinase pathway.MEK1 regulates various cellular processes such as growth, adhesion, survival, and differentiation, as well as transcription, metabolism, and cytoskeletal rearrangements.MEK1 Protein, Mouse (sf9, His-GST) is the recombinant mouse-derived MEK1 protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag.

HY-P700592

	*MAP2K6 Protein, Human (sf9, His)* MAP2K6; mitogen-activated protein kinase kinase 6; MEK6; MKK6; MAPKK6; PRKMK6; SAPKK3; protein kinase, mitogen-activated, kinase 6 (MAP kinase kinase 6); EC 2.7.12.2; Dual specificity mitogen-activated protein kinase kinase 6; MAP kinase kinase 6; MAPK/ERK kinase 6	Human	Sf9 insect cells
	The MKK6 protein is a dual-specificity kinase involved in the MAP kinase pathway. MAP2K6 Protein, Human (sf9, His) is the recombinant human-derived MAP2K6 protein, expressed by sf9 insect cells , with N-6*His labeled tag.

HY-P74745

	*MKK6 Protein, Human (sf9, His-GST)* Dual specificity mitogen-activated protein kinase kinase 6; MAPKK 6; MEK 6; SAPKK3; MAP2K6	Human	Sf9 insect cells
	The MKK6 protein is a dual-specificity kinase involved in the MAP kinase pathway. MKK6 Protein, Human (sf9, His-GST) is the recombinant human-derived MKK6 protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag.

HY-P705586

	*MAP3K14 Protein, Human (sf9)* mitogen-activated protein kinase kinase kinase 14; NF-kappa-beta-inducing kinase; HsNIK; Serine/threonine-protein kinase NIK; EC:2.7.11.25	Human	Sf9 insect cells

HY-P74748

	*MKK6 Protein, Human (S207D, T211D, sf9)* Dual specificity mitogen-activated protein kinase kinase 6; MAPKK 6; MEK 6; SAPKK3; MAP2K6	Human	Sf9 insect cells
	The MKK6 protein is a dual-specificity kinase involved in the MAP kinase pathway. MKK6 Protein, Human (S207D, T211D, sf9) is the recombinant human-derived MKK6 protein, expressed by Sf9 insect cells, with tag free.

HY-P706068

	*MEKK2 Protein, Human (Active, sf9, His-GST)* mitogen-activated protein kinase kinase kinase 2; MAPK/ERK kinase kinase 2; MEK kinase 2; MEKK 2; MAPKKK2; MEKK2	Human	Sf9 insect cells

HY-P704008

	*MAPK1/ERK2 Protein, Human (Inactive, GST)* MAPK1; mitogen-activated protein kinase 1; PRKM1, PRKM2; ERK; ERK2; MAPK2; p41mapk; ERK-2; MAPK 2; p42-MAPK; MAP kinase 1; MAP kinase 2; MAP kinase isoform p42; protein tyrosine kinase ERK2; mitogen-activated protein kinase 2; extracellular signal-regulated kinase 2; p38; p40; p41; ERT1; PRKM1; PRKM2; P42MAPK	Human	E. coli
	ERK2 Protein, a key component of the MAPK/ERK cascade, regulates diverse cellular processes such as transcription, translation, mitosis, apoptosis, endosomal dynamics, and Golgi apparatus fragmentation. Through phosphorylation, it modulates substrates including transcription factors, cytoskeletal elements, apoptosis regulators, translation regulators, protein kinases, and phosphatases. MAPK1/ERK2 Protein, Human (Inactive, GST) is the recombinant human-derived MAPK1/ERK2 protein, expressed by E. coli, with N-GST labeled tag.

HY-P702743

	*MAP4K4 Protein, Human (Active, sf9, GST)* MAP4K4; mitogen-activated protein kinase kinase kinase kinase 4; FLH21957; hepatocyte progenitor kinase like/germinal center kinase like kinase; HGK; HPK/GCK like kinase; NIK	Human	Sf9 insect cells
	MAP4K4 Protein, Human (sf9, GST) is the recombinant human-derived MAP4K4, expressed by Sf9 insect cells , with GST labeled tag. ,

HY-P705939

	*DUSP4 Protein, Human (His)* Dual specificity protein phosphatase 4; Dual specificity protein phosphatase hVH2; mitogen-activated protein kinase phosphatase 2 (MAP kinase phosphatase 2; MKP-2); DUSP4; ; MKP2; VH2	Human	E. coli

HY-P706075

	*MEK1 Protein, Human (Inactive, K97R, sf9, GST)* Dual specificity mitogen-activated protein kinase kinase 1; ERK activator kinase 1; MAPK/ERK kinase 1; MEK 1; MEK1; PRKMK1	Human	Sf9 insect cells

HY-P702735

	*MAPK1/ERK2 Protein, Human (Active, Flag-His)* MAPK1; mitogen-activated protein kinase 1; PRKM1, PRKM2; ERK; ERK2; MAPK2; p41mapk; ERK-2; MAPK 2; p42-MAPK; MAP kinase 1; MAP kinase 2; MAP kinase isoform p42; protein tyrosine kinase ERK2; mitogen-activated protein kinase 2; extracellular signal-regulated kinase 2; p38; p40; p41; ERT1; PRKM1; PRKM2; P42MAPK	Human	E. coli
	ERK2 Protein, a key component of the MAPK/ERK cascade, regulates diverse cellular processes such as transcription, translation, mitosis, apoptosis, endosomal dynamics, and Golgi apparatus fragmentation. Through phosphorylation, it modulates substrates including transcription factors, cytoskeletal elements, apoptosis regulators, translation regulators, protein kinases, and phosphatases. MAPK1 Protein, Human (Active, Flag, His) is the recombinant human-derived MAPK1, expressed by E. coli, with N-His, N-Flag labeled tag.

HY-P701705

	*ASK1 Protein, Human (His)* MAP3K5; mitogen-activated protein kinase kinase kinase 5; Apoptosis signal-regulating kinase 1; ASK-1; MAPK/ERK kinase kinase 5; MEK kinase 5; MEKK 5	Human	E. coli
	ASK1 protein is a key serine/threonine kinase in the MAP kinase pathway, coordinating cellular responses to environmental changes and affecting cell fate, differentiation, and survival. ASK1 is a key player in apoptosis and promotes mitochondria-dependent caspase activation. ASK1 Protein, Human (His) is the recombinant human-derived ASK1 protein, expressed by E. coli , with C-6*His labeled tag.

HY-P701679

	*ERK3 Protein, Human (Inactive, L290V)* MAPK6; mitogen-activated protein kinase 6; MAP kinase 6; MAPK 6; Extracellular signal-regulated kinase 3; ERK-3; MAP kinase isoform p97; p97-MAPK	Human	E. coli
	ERK3 Protein, an atypical MAPK, phosphorylates MAP2 and MAPKAPK5. Interacting with MAPKAPK5, ERK3/MAPK6 undergoes Ser-189 phosphorylation, facilitating MAPKAPK5 activation. Activated MAPKAPK5 reciprocally phosphorylates ERK3/MAPK6. The complex's precise functional implications, especially in cell cycle entry, remain elusive. ERK3 Protein, Human (L290V) is the recombinant human-derived ERK3 protein, expressed by E. coli , with tag free.

HY-P701803

	*MAPK4 Protein, Human (sf9, His, GST)* MAPK4; mitogen-activated protein kinase 4; MAP kinase 4; MAPK 4; Extracellular signal-regulated kinase 4; ERK-4; MAP kinase isoform p63; p63-MAPK	Human	Sf9 insect cells
	MAPK4, an atypical MAPK protein, phosphorylates microtubule-associated protein 2 (MAP2) and MAPKAPK5, forming a complex with intricate phosphorylation events. Interaction with MAPKAPK5 leads to ERK3/MAPK6 phosphorylation at Ser-189, activating MAPKAPK5, which reciprocally phosphorylates ERK3/MAPK6. The specific cellular role of this interplay, while unclear, suggests ERK3's potential involvement in promoting entry into the cell cycle. MAPK4 Protein, Human (sf9, His, GST) is the recombinant human-derived MAPK4 protein, expressed by sf9 insect cells , with N-8*His, N-GST labeled tag.

HY-P706069

	*MAP3K3/MEKK3 Protein, Human (Active, sf9, His-GST)* mitogen-activated protein kinase kinase kinase 3; MAPK/ERK kinase kinase 3; MEK kinase 3; MEKK 3; MAPKKK3; MEKK3	Human	Sf9 insect cells

HY-P701680

	*ERK3 Protein, Human (Inactive, L290V, His)* MAPK6; mitogen-activated protein kinase 6; MAP kinase 6; MAPK 6; Extracellular signal-regulated kinase 3; ERK-3; MAP kinase isoform p97; p97-MAPK	Human	E. coli
	ERK3 Protein, an atypical MAPK, phosphorylates MAP2 and MAPKAPK5. Interacting with MAPKAPK5, ERK3/MAPK6 undergoes Ser-189 phosphorylation, facilitating MAPKAPK5 activation. Activated MAPKAPK5 reciprocally phosphorylates ERK3/MAPK6. The complex's precise functional implications, especially in cell cycle entry, remain elusive. ERK3 Protein, Human (L290V, His) is the recombinant human-derived ERK3 protein, expressed by E. coli , with N-6*His labeled tag.

HY-P702662

	*MAPKAPK2 Protein, Human (Active)* MAPKAPK2; mitogen-activated protein kinase-activated protein kinase 2; MAP kinase-activated protein kinase 2; MAPKAP kinase 2; MAPK-activated protein kinase 2; MK2; MK-2; MAPKAP-K2	Human	E. coli
	The MAPKAPK2 protein is a stress-activated kinase involved in multiple cellular processes, including cytokine production, endocytosis, cytoskeletal reorganization, cell migration, cell cycle control, chromatin remodeling, DNA damage response, and transcriptional regulation. MAPKAPK2 Protein, Human (323a.a) is the recombinant human-derived MAPKAPK2, expressed by E. coli, with tag-free.

HY-P702934

	*MAPK15 Protein, Human (Active, sf9, His-GST)* mitogen-activated protein kinase 15 Curated; MAPK 15; Extracellular signal-regulated kinase 7 (ERK-7); Extracellular signal-regulated kinase 8 (ERK-8); MAPK15 Imported; ERK7 By similarity	Human	Sf9 insect cells
	MAPK15 Protein, Human (Active, sf9, His-GST) is the recombinant human-derived MAPK15, expressed by Sf9 insect cells , with N-6*His and N-GST labeled tag.

HY-P706070

	*MAP4K1/HPK1 Protein, Human (Active, sf9, His-GST)* mitogen-activated protein kinase kinase kinase kinase 1; Hematopoietic progenitor kinase; MAPK/ERK kinase kinase kinase 1; MEK kinase kinase 1; MEKKK 1; HPK1	Human	Sf9 insect cells

HY-P706071

	*MAP4K5/KHS1 Protein, Human (Active, sf9, His-GST)* mitogen-activated protein kinase kinase kinase kinase 5; Kinase homologous to SPS1/STE20; KHS; MAPK/ERK kinase kinase kinase 5; MEK kinase kinase 5; MEKKK 5	Human	Sf9 insect cells

HY-P705577

	*MAPK8/JNK1 Protein, Human* mitogen-activated protein kinase 8; MAP kinase 8; JNK-46; Stress-activated protein kinase 1c (SAPK1c); c-Jun N-terminal kinase 1; JNK1; PRKM8; SAPK1; SAPK1C; EC:2.7.11.24	Human	E. coli

HY-P701640

	*TAB1 Protein, Human* TAB1; TGF-beta-activated kinase 1 and MAP3K7-binding protein 1; mitogen-activated protein kinase kinase kinase 7-interacting protein 1; TGF-beta-activated kinase 1-binding protein 1; TAK1-binding protein 1	Human	E. coli
	The TAB1 protein is a key adapter that activates JNK, NF-kappa-B, and proinflammatory cytokines in response to TLR and cytokine stimulation. It binds to MAP3K7/TAK1, inducing autophosphorylation and full activation. TAB1 Protein, Human is the recombinant human-derived TAB1 protein, expressed by E. coli , with tag free.

HY-P701639

	*TAB1 Protein, Human (His)* TAB1; TGF-beta-activated kinase 1 and MAP3K7-binding protein 1; mitogen-activated protein kinase kinase kinase 7-interacting protein 1; TGF-beta-activated kinase 1-binding protein 1; TAK1-binding protein 1	Human	E. coli
	The TAB1 protein is a key adapter that activates JNK, NF-kappa-B, and proinflammatory cytokines in response to TLR and cytokine stimulation. It binds to MAP3K7/TAK1, inducing autophosphorylation and full activation. TAB1 Protein, Human (His) is the recombinant human-derived TAB1 protein, expressed by E. coli , with N-6*His labeled tag.

HY-P701791

	*JNK3 Protein, Human (His)* MAPK10; mitogen-activated protein kinase 10; MAP kinase 10; MAPK 10; MAP kinase p49 3F12; Stress-activated protein kinase 1b; SAPK1b; Stress-activated protein kinase JNK3; c-Jun N-terminal kinase 3	Human	E. coli
	JNK3 is a critical serine/threonine protein kinase in neuronal processes, regulating proliferation, differentiation, migration, and apoptosis. Activation through MAP2K4/MKK4 and MAP2K7/MKK7 leads to phosphorylation of JNK3, which in turn phosphorylates AP-1 components such as JUN and ATF2, thereby regulating AP-1 transcriptional activity. JNK3 Protein, Human (His) is the recombinant human-derived JNK3 protein, expressed by E. coli , with N-6*His labeled tag.

HY-P700589

	*MAP2K4 Protein, Human (P. pastoris, His-GST)* MAP2K4; mitogen-activated protein kinase kinase 4; SERK1; dual specificity mitogen-activated protein kinase kinase 4; JNKK1; MEK4; MKK4; PRKMK4; MEK 4; MAPKK 4; SAPK kinase 1; MAPK/ERK kinase 4; SAPK/ERK kinase 1; MAP kinase kinase 4; JNK-activated kinase 1; JNK activating kinase 1; JNK-activating kinase 1; c-Jun N-terminal kinase kinase 1; stress-activated protein kinase kinase 1; JNKK; SEK1; MAPKK4; SAPKK1; SAPKK-1;	Human	P. pastoris
	The MAP2K4 protein is a dual-specificity kinase involved in the MAP kinase pathway. MAP2K4 Protein, Human (P. pastoris, His-GST) is the recombinant human-derived MAP2K4 protein, expressed by P. pastoris , with N-6*His, N-GST labeled tag.

HY-P701801

	*MAP4K6 Protein, Human (Active, sf9, GST)* MINK1; Misshapen-like kinase 1; GCK family kinase MiNK; MAPK/ERK kinase kinase kinase 6; MEK kinase kinase 6; MEKKK 6; Misshapen/NIK-related kinase; mitogen-activated protein kinase kinase kinase kinase 6	Human	Sf9 insect cells
	MAP4K6 protein is a key serine/threonine kinase that negatively regulates Ras-related Rap2-mediated signaling, affecting neuronal structure and AMPA receptor trafficking. Its importance is underlined by its important role in regulating synaptic density, dendritic complexity, and surface AMPA receptor expression in hippocampal neurons. MAP4K6 Protein, Human (sf9, GST) is the recombinant human-derived MAP4K6 protein, expressed by sf9 insect cells , with N-GST labeled tag.

HY-P701678

	*ERK1 Protein, Human (Active, GST)* MAPK3; mitogen-activated protein kinase 3; MAP kinase 3; MAPK 3; ERT2; Extracellular signal-regulated kinase 1; ERK-1; Insulin-stimulated MAP2 kinase; MAP kinase isoform p44; p44-MAPK; Microtubule-associated protein 2 kinase; p44-ERK1	Human	E. coli
	ERK1 protein is an important serine/threonine kinase in the MAP kinase pathway and cooperates with MAPK1/ERK2 to activate the MAPK/ERK cascade. Stimulated by KIT and KITLG/SCF, this pathway plays a key role in cell growth, adhesion, survival, and differentiation. ERK1 Protein, Human (GST) is the recombinant human-derived ERK1 protein, expressed by E. coli , with N-GST labeled tag.

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Cat. No.	Product Name	Chemical Structure

HY-159846S

Luvometinib-d
Luvometinib-d is the deuterium labeled Luvometinib (HY-159846). Luvometinib is a mitogen-activated protein kinase (MEK) inhibitor with antitumor activity .

HY-W355700S

1-Oleoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine-d31

1-Oleoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine-d₃₁ is the deuterium labeled 1-Oleoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine (HY-W355700). 1-oleoyl-sn-glycero-3-phosphoethanolamine (LysoPE 18:1) is a lysophosphatidylethanolamine molecule involved in phospholipid metabolism, targeting cell membrane receptors (such as G protein-coupled receptors) to regulate cell signaling pathways. 1-oleoyl-sn-glycero-3-phosphoethanolamine may activate mitogen-activated protein kinase (MAPK) signaling, promote cell migration, regulate inflammatory responses and lipid metabolism, and has both pro-inflammatory and anti-inflammatory activities. 1-oleoyl-sn-glycero-3-phosphoethanolamine is mainly used in the screening of biomarkers for metabolic diseases (such as non-alcoholic fatty liver disease and obesity), as well as the study of the mechanism of lysophospholipids in cell membrane homeostasis and signal transduction .

Host:	Mouse (28) Rabbit (61)
Reactivity:	Human (87) Bovine (1) Rat (63) Mouse (68) Monkey (4) Dog (1) Hamster (2) Pig (1)
Application:	IHC-P (34) ICC/IF (47) IF-Tissue (9) IP (34) IHC-F (7) WB (86) FC (23) ELISA (23)
Isotype:	IgG (65) IgG1 (7) IgG2a (2) IgG/Kappa (1) IgG2b (2)
Conjugation:	Non-conjugated (89) Biotin (2)
Clonality:	Polyclonal (6) Monoclonal (57) Recombinant (23)
Modification:	Phosphorylated (10) Unmodified (53)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P87165

	p38 gamma/MAPK12 Antibody (YA6858) ERK 6 antibody; ERK-6 antibody; ERK6 antibody; Extracellular signal-regulated kinase 6 antibody; MAP kinase 12 antibody; MAP kinase p38 gamma antibody; MAPK 12 antibody; Mapk12 antibody; mitogen Activated Protein Kinase 12 antibody; mitogen activated protein kinase p38 gamma antibody; ERK 6 antibody; ERK-6 antibody; ERK6 antibody; Extracellular signal-regulated kinase 6 antibody; MAP kinase 12 antibody; MAP kinase p38 gamma antibody; MAPK 12 antibody; Mapk12 antibody; mitogen Activated Protein Kinase 12 antibody; mitogen activated protein kinase p38 gamma antibody; mitogen-activated protein kinase 12 antibody; mitogen-activated protein kinase p38 gamma antibody; MK12_HUMAN antibody; P38 GAMMA antibody; P38GAMMA antibody; PRKM12 antibody; SAPK 3 antibody; SAPK-3 antibody; SAPK3 antibody; Stress Activated Protein Kinase 3 antibody; Stress-activated protein kinase 3 antibody;	WB, IHC-P, ICC/IF, FC	Human, Mouse, Rat
	p38 gamma/MAPK12 Antibody (YA6858) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to p38 gamma/MAPK12.

HY-P87297

	SIN1 Antibody (YA6980) MAPKAP 1 antibody; MAPKAP1 antibody; MEKK2 interacting protein 1 antibody; MGC2745 antibody; MIP 1 antibody; MIP1 antibody; mitogen activated protein kinase associated protein 1 antibody; mitogen-activated protein kinase 2-associated protein 1 antibody; mSIN1 antibody; OTTHUMP00000064207 antibody	WB	Human
	SIN1 Antibody (YA6980) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to SIN1.

HY-P85311

	p38β Antibody (YA5003) MAPK11; PRKM11; SAPK2; SAPK2B; mitogen-activated protein kinase 11; MAP kinase 11; MAPK 11; mitogen-activated protein kinase p38 beta; MAP kinase p38 beta; p38b; Stress-activated protein kinase 2b; SAPK2b; p38-2	WB, ELISA	Human
	p38β Antibody (YA5003) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to p38β.

HY-P85712

	p38 alpha/MAPK14 Antibody (YA5404) mitogen-activated protein kinase 14; MAP kinase 14; MAPK 14; Cytokine suppressive anti-inflammatory drug-binding protein; CSAID-binding protein; CSBP; MAP kinase MXI2; MAX-interacting protein 2; mitogen-activated protein kinase p38 alpha; MAP kinase p38 alpha; Stress-activated protein kinase 2a; SAPK2a;	WB, ICC/IF, ELISA	Human, Mouse, Rat
	p38 alpha/MAPK14 Antibody (YA5404) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to p38 alpha/MAPK14.

HY-P85835

	ERK2 Antibody (YA5527) MAPK1; ERK2; PRKM1; PRKM2; mitogen-activated protein kinase 1; MAP kinase 1; MAPK 1; ERT1; Extracellular signal-regulated kinase 2; ERK-2; MAP kinase isoform p42; p42-MAPK; mitogen-activated protein kinase 2; MAP kinase 2; MAPK 2	WB, ICC/IF, ELISA	Human, Mouse, Rat
	ERK2 Antibody (YA5527) is a Mouse-derived and non-conjugated IgG monoclonal antibody, targeting to ERK2.

HY-P86460

	p38 alpha/MAPK14 Antibody (YA6152) mitogen-activated protein kinase 14; MAP kinase 14; MAPK 14; Cytokine suppressive anti-inflammatory drug-binding protein; CSAID-binding protein; CSBP; MAP kinase MXI2; MAX-interacting protein 2; mitogen-activated protein kinase p38 alpha; MAP kinase p38 alpha; Stress-activated protein kinase 2a; SAPK2a;	WB, ICC/IF, IP, ELISA	Human, Mouse, Rat
	p38 alpha/MAPK14 Antibody (YA6152) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to p38 alpha/MAPK14.

HY-P85516

	MEK1 Antibody (YA5208) AA589381; Dual specificity mitogen-activated protein kinase kinase 1; Dual specificity mitogen-activated protein kinase kinase 2; ERK activator kinase 1; ERK activator kinase 2; FLJ26075; MAP kinase kinase 1; MAP kinase kinase 2; MAP2K1; MAP2K2; MAPK/ERK kinase 1; MAPK/ERK kinase 2; MAPKK 1; MAPKK1; MAPKK2; MEK 1; MEKK1; mitogen activated protein kinase kinase 1; mitogen activated protein kinase kinase 2; mitogen-activated protein kinase kinase 2, p45; MK2; MKK 1; MKK 2; MKK1; MKK2; MP2K1_HUMAN; PRKMK 1; PRKMK 2; Prkmk1; Prkmk2; protein kinase, mitogen-activated, kinase 1; MAP kinase kinase 1; Protein kinase, mitogen-activated, kinase 1; Protein kinase, mitogen-activated, kinase 2.	WB	Human
	MEK1 Antibody (YA5208) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to MEK1.

HY-P86457

	MEK-1/2 Antibody (YA6149) MAP2K1; MEK1; PRKMK1; Dual specificity mitogen-activated protein kinase kinase 1; MAP kinase kinase 1; MAPKK 1; MKK1; ERK activator kinase 1; MAPK/ERK kinase 1; MEK 1; MAP2K2; MEK2; MKK2; PRKMK2; Dual specificity mitogen-activated protein k	WB, IHC-P, ICC/IF, IP, ELISA	Human, Mouse, Rat
	MEK-1/2 Antibody (YA6149) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MEK-1/2.

HY-P80776A

	Phospho-p38 alpha/MAPK14 (Thr180+Tyr182) Antibody 1 Publications Verification p38 (phospho T180 + Y182); p-p38 (phospho T180 + Y182); p38 (phospho T180/Y182); CSAID Binding Protein 1; CSAID binding protein; CSAID-binding protein; Csaids binding protein; CSBP 1; CSBP 2; CSBP; CSBP1; CSBP2; CSPB 1; CSPB1; Cytokine suppressive anti inflammatory drug binding protein; Cytokine suppressive anti-inflammatory drug-binding protein; EXIP; MAP kinase 14; MAP kinase MXI2; MAP kinase p38 alpha; MAPK 14; MAPK14; MAX interacting protein 2; MAX-interacting protein 2; mitogen Activated Protein Kinase 14; mitogen activated protein kinase p38 alpha; mitogen-activated protein kinase 14; mitogen-activated protein kinase p38 alpha; MK14_HUMAN; Mxi 2; Mxi2; p38 ALPHA; p38; p38 MAP kinase; p38 MAPK; p38 mitogen activated protein kinase; p38ALPHA; p38alpha Exip; PRKM14; PRKM15; RK; SAPK 2A; SAPK2A; Stress Activated Protein Kinase 2A.	WB, IHC-P, FC, ICC/IF, ELISA	Human, Mouse
	Phospho-p38 alpha/MAPK14 (Thr180+Tyr182) Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to Phospho-p38 alpha/MAPK14 (Thr180+Tyr182).

HY-P83469

	MEK3 Antibody (YA3214) AW212142; dual specificity mitogen activated protein kinase kinase 3; Dual specificity mitogen activated protein kinase kinase 6; Dual specificity mitogen-activated protein kinase kinase 3; MAP kinase kinase 3; MAP kinase kinase 6; map2k3; MAP2K6; MAPK ERK kinase 3; MAPK/ERK kinase 3; MAPK/ERK kinase 6; MAPKK 3; MAPKK 6; MAPKK3; MAPKK6; MEK 3; MEK 6; MEK3; mitogen activated protein kinase kinase 3; mitogen activated protein kinase kinase 6; MKK 3; MKK3; MKK6; mMKK3b; MP2K3_HUMAN; PRKMK 3; PRKMK3; PRKMK6; Protein kinase; mitogen activated; kinase 6 (MAP kinase kinase 6); protein kinase; mitogen-activated; kinase 3; SAPK kinase 2; SAPKK 2; SAPKK 3; SAPKK-2; SAPKK2; SAPKK3; Stress activated protein kinase kinase 2; Stress activated protein kinase kinase 3; Stress-activated protein kinase kinase 2.	WB, ICC/IF, IP	Human, Mouse, Rat
	MEK3 Antibody (YA3214) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MEK3.

HY-P87386

	p38 beta/MAPK11 + p38 gamma/MAPK12 + p38 delta/MAPK13 Antibody (YA7069) ERK 6 antibody; ERK-6 antibody; ERK6 antibody; Extracellular signal-regulated kinase 6 antibody; MAP kinase 12 antibody; MAP kinase p38 gamma antibody; MAPK 12 antibody; Mapk12 antibody; mitogen Activated Protein Kinase 12 antibody; mitogen activated protein kinase p38 gamma antibody	WB	Human, Mouse, Rat, Monkey
	p38 beta/MAPK11 + p38 gamma/MAPK12 + p38 delta/MAPK13 Antibody (YA7069) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to p38 beta/MAPK11 + p38 gamma/MAPK12 + p38 delta/MAPK13.

HY-P80908

	TAK1 Antibody (YA663) 1 Publications Verification MAP3K7; TAK1; mitogen-activated protein kinase kinase kinase 7; Transforming growth factor-beta-activated kinase 1; TGF-beta-activated kinase 1	WB	Human, Mouse, Rat, Monkey
	TAK1 Antibody (YA663) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to TAK1.

HY-P86498

	TAK1 Antibody (YA6190) MAP3K7; TAK1; mitogen-activated protein kinase kinase kinase 7; Transforming growth factor-beta-activated kinase 1; TGF-beta-activated kinase 1	WB, ICC/IF, IP, ELISA	Human, Mouse, Rat
	TAK1 Antibody (YA6190) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to TAK1.

HY-P810590

	Phospho-MEK3 (Ser189)+MEK6 (Ser207) Antibody (YA9854) AW212142; dual specificity mitogen activated protein kinase kinase 3; Dual specificity mitogen activated protein kinase kinase 6; Dual specificity mitogen-activated protein kinase kinase 3; MAP kinase kinase 3; MAP kinase kinase 6; map2k3; MAP2K6; MAPK ERK kinase 3; MAPK/ERK kinase 3; MAPK/ERK kinase 6; MAPKK 3; MAPKK 6; MAPKK3; MAPKK6; MEK 3; MEK 6; MEK3; mitogen activated protein kinase kinase 3; mitogen activated protein kinase kinase 6; MKK 3; MKK3; MKK6; mMKK3b; MP2K3_HUMAN; PRKMK 3; PRKMK3; PRKMK6; Protein kinase; mitogen activated; kinase 6 (MAP kinase kinase 6); protein kinase; mitogen-activated; kinase 3; SAPK kinase 2; SAPKK 2; SAPKK 3; SAPKK-2; SAPKK2; SAPKK3; Stress activated protein kinase kinase 2; Stress activated protein kinase kinase 3; Stress-activated protein kinase kinase 2.	WB	Human, Mouse
	Phospho-MEK3 (Ser189)+MEK6 (Ser207) Antibody (YA9854) is a Rabbit-derived and non-conjugated IgG Recombinant, Monoclonal antibody, targeting to Phospho-MEK3 (Ser189)+MEK6 (Ser207).

HY-P83469A

	MEK3 Antibody (YA3214)(PBS only) AW212142; dual specificity mitogen activated protein kinase kinase 3; Dual specificity mitogen activated protein kinase kinase 6; Dual specificity mitogen-activated protein kinase kinase 3; MAP kinase kinase 3; MAP kinase kinase 6; map2k3; MAP2K6; MAPK ERK kinase 3; MAPK/ERK kinase 3; MAPK/ERK kinase 6; MAPKK 3; MAPKK 6; MAPKK3; MAPKK6; MEK 3; MEK 6; MEK3; mitogen activated protein kinase kinase 3; mitogen activated protein kinase kinase 6; MKK 3; MKK3; MKK6; mMKK3b; MP2K3_HUMAN; PRKMK 3; PRKMK3; PRKMK6; Protein kinase; mitogen activated; kinase 6 (MAP kinase kinase 6); protein kinase; mitogen-activated; kinase 3; SAPK kinase 2; SAPKK 2; SAPKK 3; SAPKK-2; SAPKK2; SAPKK3; Stress activated protein kinase kinase 2; Stress activated protein kinase kinase 3; Stress-activated protein kinase kinase 2.	WB, ICC/IF, IP	Human, Mouse, Rat
	MEK3 Antibody (YA3214) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MEK3.

HY-P83470

	MEKK2 Antibody (YA3215) MAP3K2; MAPKKK2; MEKK2; mitogen-activated protein kinase kinase kinase 2; MAPK/ERK kinase kinase 2; MEK kinase 2; MEKK 2	WB, ICC/IF, IP	Human, Mouse, Rat
	MEKK2 Antibody (YA3215) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MEKK2.

HY-P85273

	MEKK2 Antibody (YA4965) MAP3K2; MAPKKK2; MEKK2; mitogen-activated protein kinase kinase kinase 2; MAPK/ERK kinase kinase 2; MEK kinase 2; MEKK 2	WB, IHC-P, IHC-F, ICC/IF, IF-Tissue, IP, FC	Human, Mouse, Rat
	MEKK2 Antibody (YA4965) is a Rabbit-derived and non-conjugated monoclonal antibody, targeting to MEKK2.

HY-P80908A

	TAK1 Antibody (YA663)(PBS only) MAP3K7; TAK1; mitogen-activated protein kinase kinase kinase 7; Transforming growth factor-beta-activated kinase 1; TGF-beta-activated kinase 1	WB	Human, Mouse, Rat, Monkey
	TAK1 Antibody (YA663) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to TAK1.

HY-P80858

	Phospho-TAK1 (Ser439) Antibody (YA144) 1 Publications Verification MAP3K7; TAK1; mitogen-activated protein kinase kinase kinase 7; Transforming growth factor-beta-activated kinase 1; TGF-beta-activated kinase 1	WB, ICC/IF, IP	Human, Mouse, Rat
	Phospho-TAK1 (Ser439) Antibody (YA144) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Phospho-TAK1 (Ser439).

HY-P810681

	Phospho-TAK1 (Ser412) Antibody (YA9939) MAP3K7; TAK1; mitogen-activated protein kinase kinase kinase 7; Transforming growth factor-beta-activated kinase 1; TGF-beta-activated kinase 1	WB, FC	Human, Mouse, Rat
	Phospho-TAK1 (Ser412) Antibody (YA9939) is a Rabbit-derived and non-conjugated IgG Recombinant, Monoclonal antibody, targeting to Phospho-TAK1 (Ser412).

HY-P86654

	ERK1/2 Antibody (YA6346) ERK1+ERK2; ERK 1; ERK 2; ERK-2; ERK1; ERK2; ERT1; ERT2; Extracellular signal regulated kinase 1; Extracellular signal regulated kinase 2; Extracellular signal-regulated kinase 2; HS44KDAP; HUMKER1A; Insulin stimulated MAP2 kinase; MAP kinase 1; MAP kinase 2; MAP kinase isoform p42; MAP kinase isoform p44; MAPK 1; MAPK 2; MAPK 3; MAPK1; MAPK2; MAPK3; MGC20180; Microtubule associated protein 2 kinase; mitogen activated protein kinase 1; mitogen activated protein kinase 2; mitogen activated protein kinase 3; mitogen-activated protein kinase 1; mitogen-activated protein kinase 2; MK01_HUMAN; MK03_HUMAN; p38; p40; p41; p41mapk; p42 MAPK; p42-MAPK; p42MAPK; p44 ERK1; p44 MAPK; p44ERK1; p44MAPK; PRKM 1; PRKM 2; PRKM 3; PRKM1; PRKM2; PRKM3; Protein kinase mitogen activated 1; Protein kinase mitogen activated 2; Protein kinase mitogen activated 3; Protein tyrosine kinase ERK 2.	WB, IHC-P, IHC-F, ICC/IF, IF-Tissue, FC	Human, Mouse, Rat
	ERK1/2 Antibody (YA6346) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to ERK1/2.

HY-P83492

	MLK3 Antibody (YA3237) MAP3K11; MLK3; PTK1; SPRK; mitogen-activated protein kinase kinase kinase 11; Mixed lineage kinase 3; Src-homology 3 domain-containing proline-rich kinase	WB, ICC/IF	Human
	MLK3 Antibody (YA3237) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MLK3.

HY-P80858A

	Phospho-TAK1 (Ser439) Antibody (YA144)(PBS only) MAP3K7; TAK1; mitogen-activated protein kinase kinase kinase 7; Transforming growth factor-beta-activated kinase 1; TGF-beta-activated kinase 1	WB, ICC/IF, IP	Human, Mouse, Rat
	Phospho-TAK1 (Ser439) Antibody (YA144) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Phospho-TAK1 (Ser439).

HY-P83470A

	MEKK2 Antibody (YA3215)(PBS only) MAP3K2; MAPKKK2; MEKK2; mitogen-activated protein kinase kinase kinase 2; MAPK/ERK kinase kinase 2; MEK kinase 2; MEKK 2	WB, ICC/IF, IP	Human, Mouse, Rat
	MEKK2 Antibody (YA3215) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MEKK2.

HY-P83492A

	MLK3 Antibody (YA3237)(PBS only) MAP3K11; MLK3; PTK1; SPRK; mitogen-activated protein kinase kinase kinase 11; Mixed lineage kinase 3; Src-homology 3 domain-containing proline-rich kinase	WB, ICC/IF	Human
	MLK3 Antibody (YA3237) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MLK3.

HY-P82888

	MEKK3 Antibody (YA2633) MAP/ERK kinase kinase 3; MAP3K3; MAPK/ERK kinase kinase 3; MAPKKK3; MEK kinase 3; MEKK 3; MEKK3; mitogen activated protein kinase kinase kinase 3	WB, IHC-P, ICC/IF, IP, FC	Human, Mouse, Rat
	MEKK3 Antibody (YA2633) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MEKK3.

HY-P83395

	MEK5 Antibody (YA3140) MAP2K5; MEK5; MKK5; PRKMK5; Dual specificity mitogen-activated protein kinase kinase 5; MAP kinase kinase 5; MAPKK 5; MAPK/ERK kinase 5; MEK 5	WB, ICC/IF	Human
	MEK5 Antibody (YA3140) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MEK5.

HY-P80549

	ASK1 Antibody 1 Publications Verification MAP3K5; ASK1; MAPKKK5; MEKK5; mitogen-activated protein kinase kinase kinase 5; Apoptosis signal-regulating kinase 1; ASK-1; MAPK/ERK kinase kinase 5; MEK kinase 5; MEKK 5	WB, IHC-P, ICC/IF, FC	Human, Mouse
	ASK1 Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to ASK1.

HY-P80645

	DUSP1 Antibody 1 Publications Verification DUSP1; CL100; MKP1; PTPN10; VH1; Dual specificity protein phosphatase 1; Dual specificity protein phosphatase hVH1; mitogen-activated protein kinase phosphatase 1; MAP kinase phosphatase 1; MKP-1; Protein-tyrosine phosphatase CL100	WB, IHC-P, ICC/IF, IP, FC	Human, Mouse, Rat
	DUSP1 Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to DUSP1.

HY-P86354

	ERK5 Antibody (YA6046) MAPK7; BMK1; ERK5; PRKM7; mitogen-activated protein kinase 7; MAP kinase 7; MAPK 7; Big MAP kinase 1; BMK-1; Extracellular signal-regulated kinase 5; ERK-5	WB, ICC/IF, IP, ELISA	Human, Mouse, Rat
	ERK5 Antibody (YA6046) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to ERK5.

HY-P85152

	MAPK6/ERK3 Antibody (YA4844) MAPK6; ERK3; PRKM6; mitogen-activated protein kinase 6; MAP kinase 6; MAPK 6; Extracellular signal-regulated kinase 3; ERK-3; MAP kinase isoform p97; p97-MAPK	WB, FC, ELISA	Human
	MAPK6/ERK3 Antibody (YA4844) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to MAPK6/ERK3.

HY-P85717

	JNK2 Antibody (YA5409) mitogen-activated protein kinase 9; MAP kinase 9; MAPK 9; JNK-55; Stress-activated protein kinase 1a; SAPK1a; Stress-activated protein kinase JNK2; c-Jun N-terminal kinase 2;	IHC-P	Human, Mouse, Rat
	JNK2 Antibody (YA5409) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to JNK2.

HY-P86742

	ERK1/2 Antibody (YA6434) ERK; ERK-1; ERT 2; ERT2; Extracellular Signal Regulated Kinase 1; Extracellular signal related kinase 1; Extracellular signal-regulated kinase 1; HGNC6877; HS44KDAP; HUMKER1A; Insulin Stimulated MAP2 Kinase; Insulin-stimulated MAP2 kinase; MAP kinase 1; MAP kinase 3; MAP Kinase; MAP kinase isoform p44; MAPK 1; MAPK 3; MAPK; MAPK1; Mapk3; MGC20180; Microtubule Associated Protein 2 Kinase; Microtubule-associated protein 2 kinase; mitogen Activated Protein Kinase 3; mitogen-activated protein kinase 1; mitogen-activated protein kinase 3; MK03_HUMAN; OTTHUMP00000174538; OTTHUMP00000174541; p44 ERK1; p44 MAPK; p44-ERK1; p44-MAPK; P44ERK1; P44MAPK; PRKM 3; PRKM3; Protein Kinase mitogen Activated 3.	WB, IHC-P, IHC-F, IF-Tissue, FC	Human, Mouse, Rat
	ERK1/2 Antibody (YA6434) is a Mouse-derived and non-conjugated IgG monoclonal antibody, targeting to ERK1/2.

HY-P86742A

	ERK1/2 Antibody (YA6434)(PBS only) ERK; ERK-1; ERT 2; ERT2; Extracellular Signal Regulated Kinase 1; Extracellular signal related kinase 1; Extracellular signal-regulated kinase 1; HGNC6877; HS44KDAP; HUMKER1A; Insulin Stimulated MAP2 Kinase; Insulin-stimulated MAP2 kinase; MAP kinase 1; MAP kinase 3; MAP Kinase; MAP kinase isoform p44; MAPK 1; MAPK 3; MAPK; MAPK1; Mapk3; MGC20180; Microtubule Associated Protein 2 Kinase; Microtubule-associated protein 2 kinase; mitogen Activated Protein Kinase 3; mitogen-activated protein kinase 1; mitogen-activated protein kinase 3; MK03_HUMAN; OTTHUMP00000174538; OTTHUMP00000174541; p44 ERK1; p44 MAPK; p44-ERK1; p44-MAPK; P44ERK1; P44MAPK; PRKM 3; PRKM3; Protein Kinase mitogen Activated 3.	WB, IHC-P, IHC-F, IF-Tissue, FC	Human, Mouse, Rat
	ERK1/2 Antibody (YA6434) is a Mouse-derived and non-conjugated IgG monoclonal antibody, targeting to ERK1/2.

HY-P83405

	JNK3 Antibody (YA3150) mitogen-activated protein kinase 10; MAP kinase 10; MAPK 10; MAP kinase p49 3F12; Stress-activated protein kinase 1b; SAPK1b; MAPK10; JNK3; JNK3A; PRKM10; SAPK1B	WB, ICC/IF, FC	Human, Mouse, Rat
	JNK3 Antibody (YA3150) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to JNK3.

HY-P85046

	ASK1 Antibody (YA4738) MAP3K5; ASK1; MAPKKK5; MEKK5; mitogen-activated protein kinase kinase kinase 5; Apoptosis signal-regulating kinase 1; ASK-1; MAPK/ERK kinase kinase 5; MEK kinase 5; MEKK 5	WB, IHC-P, ICC/IF, FC, ELISA	Human
	ASK1 Antibody (YA4738) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to ASK1.

HY-P86322

	ASK1 Antibody (YA6014) MAP3K5; ASK1; MAPKKK5; MEKK5; mitogen-activated protein kinase kinase kinase 5; Apoptosis signal-regulating kinase 1; ASK-1; MAPK/ERK kinase kinase 5; MEK kinase 5; MEKK 5	WB, IHC-P, ICC/IF, IP, ELISA	Human, Mouse
	ASK1 Antibody (YA6014) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to ASK1.

HY-P80792

	Phospho-ASK1 (Ser966) Antibody 1 Publications Verification MAP3K5; ASK1; MAPKKK5; MEKK5; mitogen-activated protein kinase kinase kinase 5; Apoptosis signal-regulating kinase 1; ASK-1; MAPK/ERK kinase kinase 5; MEK kinase 5; MEKK 5	WB, IHC-P	Human, Mouse, Rat
	Phospho-ASK1 (Ser966) Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to Phospho-ASK1 (Ser966).

HY-P83314

	MEK2 Antibody (YA3059) MAP2K2; MEK2; MKK2; PRKMK2; Dual specificity mitogen-activated protein kinase kinase 2; MAP kinase kinase 2; MAPKK 2; ERK activator kinase 2; MAPK/ERK kinase 2; MEK 2	WB, IHC-P, ICC/IF, FC	Human, Mouse
	MEK2 Antibody (YA3059) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MEK2.

HY-P81378

	MAP4K4/NIK Antibody (YA1123) MAP4K4; HGK, KIAA0687, NIK; mitogen-activated protein kinase kinase kinase kinase 4; HPK/GCK-like kinase HGK; MAPK/ERK kinase kinase kinase 4 (MEK kinase kinase 4; MEKKK 4); Nck-interacting kinase	IHC-P	Human
	MAP4K4/NIK Antibody (YA1123) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MAP4K4/NIK.

HY-P85274

	MEK2 Antibody (YA4966) MAP2K2; MEK2; MKK2; PRKMK2; Dual specificity mitogen-activated protein kinase kinase 2; MAP kinase kinase 2; MAPKK 2; ERK activator kinase 2; MAPK/ERK kinase 2; MEK 2	WB, IHC-P, IHC-F, IF-Tissue	Human, Mouse, Rat
	MEK2 Antibody (YA4966) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to MEK2.

HY-P85739

	MEK2 Antibody (YA5431) MAP2K2; MEK2; MKK2; PRKMK2; Dual specificity mitogen-activated protein kinase kinase 2; MAP kinase kinase 2; MAPKK 2; ERK activator kinase 2; MAPK/ERK kinase 2; MEK 2	WB	Human, Rat, Mouse
	MEK2 Antibody (YA5431) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to MEK2.

HY-P86470

	MEK1 Antibody (YA6162) MAP2K1; MEK1; PRKMK1; Dual specificity mitogen-activated protein kinase kinase 1; MAP kinase kinase 1; MAPKK 1; MKK1; ERK activator kinase 1; MAPK/ERK kinase 1; MEK 1	WB, IHC-P, ICC/IF, IP, ELISA	Human, Mouse, Rat
	MEK1 Antibody (YA6162) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MEK1.

HY-P85200

	MAP4K4/NIK Antibody (YA4892) MAP4K4; HGK; KIAA0687; NIK; mitogen-activated protein kinase kinase kinase kinase 4; HPK/GCK-like kinase HGK; MAPK/ERK kinase kinase kinase 4; MEK kinase kinase 4; MEKKK 4; Nck-interacting kinase	WB, FC, ELISA	Human, Mouse
	MAP4K4/NIK Antibody (YA4892) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to MAP4K4/NIK.

HY-P81378A

	MAP4K4/NIK Antibody (YA1123)(PBS only) MAP4K4; HGK, KIAA0687, NIK; mitogen-activated protein kinase kinase kinase kinase 4; HPK/GCK-like kinase HGK; MAPK/ERK kinase kinase kinase 4 (MEK kinase kinase 4; MEKKK 4); Nck-interacting kinase	IHC-P	Human
	MAP4K4/NIK Antibody (YA1123) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MAP4K4/NIK.

HY-P83314A

	MEK2 Antibody (YA3059)(PBS only) MAP2K2; MEK2; MKK2; PRKMK2; Dual specificity mitogen-activated protein kinase kinase 2; MAP kinase kinase 2; MAPKK 2; ERK activator kinase 2; MAPK/ERK kinase 2; MEK 2	WB, IHC-P, ICC/IF, FC	Human, Mouse
	MEK2 Antibody (YA3059) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MEK2.

HY-P85274A

	MEK2 Antibody (YA4966)(PBS only) MAP2K2; MEK2; MKK2; PRKMK2; Dual specificity mitogen-activated protein kinase kinase 2; MAP kinase kinase 2; MAPKK 2; ERK activator kinase 2; MAPK/ERK kinase 2; MEK 2	WB, IHC-P, IHC-F, IF-Tissue	Human, Mouse, Rat
	MEK2 Antibody (YA4966) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to MEK2.

HY-P80832

	Phospho-MEK1 (Ser298) Antibody (YA178) 1 Publications Verification MAP2K1; MEK1; PRKMK1; Dual specificity mitogen-activated protein kinase kinase 1; MAP kinase kinase 1; MAPKK 1; MKK1; ERK activator kinase 1; MAPK/ERK kinase 1; MEK 1	WB, ICC/IF	Human, Mouse, Rat
	Phospho-MEK1 (Ser298) Antibody (YA178) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Phospho-MEK1 (Ser298).

HY-P80833

	Phospho-MEK1 (Thr292) Antibody (YA177) MAP2K1; MEK1; PRKMK1; Dual specificity mitogen-activated protein kinase kinase 1; MAP kinase kinase 1; MAPKK 1; MKK1; ERK activator kinase 1; MAPK/ERK kinase 1; MEK 1	WB	Mouse, Rat
	Phospho-MEK1 (Thr292) Antibody (YA177) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Phospho-MEK1 (Thr292).

HY-P86106

	JNK2 Antibody (YA5798) MAPK9; JNK2; PRKM9; SAPK1A; mitogen-activated protein kinase 9; MAP kinase 9; MAPK 9; JNK-55; Stress-activated protein kinase 1a; SAPK1a; Stress-activated protein kinase JNK2; c-Jun N-terminal kinase 2	WB, IHC-P, ICC/IF, IP, ELISA	Human, Mouse, Rat
	JNK2 Antibody (YA5798) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to JNK2.