(R)-Zunsemetinib
Based on 1 Customer Validation
(R)-Zunsemetinib is the isomer of Zunsemetinib (HY-139553), and can be used as an experimental control. Zunsemetinib (CDD-450) is an orally active and selective p38α mitogen-activated protein kinase-activated protein kinase 2 (MK2) pathway inhibitor. Zunsemetinib can be used for the research of immuno-inflammatory diseases.
For research use only. We do not sell to patients.
- Purity: 97.84%
- CAS No.: 1640282-44-5
- Formula: C25H22ClF2N5O3
- Molecular Weight:513.92
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 1640282-44-5
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Appearance Solid
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Molecular Weight 513.92
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Formula C25H22ClF2N5O3
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Color Light yellow to yellow
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SMILES
FC1=CC(F)=CN=C1COC2=C(Cl)C(N(C3=CC(C4=NC(C(C)(C)O)=NC=C4)=NC=C3C)C(C)=C2)=O
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Synonyms
(R)-ATI-450; (R)-CDD-450
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 50 mg/mL (97.29 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (276 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.9458 mL | 9.7291 mL | 19.4583 mL | 48.6457 mL |
| 5 mM | 0.3892 mL | 1.9458 mL | 3.8917 mL | 9.7291 mL | |
| 10 mM | 0.1946 mL | 0.9729 mL | 1.9458 mL | 4.8646 mL | |
| 15 mM | 0.1297 mL | 0.6486 mL | 1.2972 mL | 3.2430 mL | |
| 20 mM | 0.0973 mL | 0.4865 mL | 0.9729 mL | 2.4323 mL | |
| 25 mM | 0.0778 mL | 0.3892 mL | 0.7783 mL | 1.9458 mL | |
| 30 mM | 0.0649 mL | 0.3243 mL | 0.6486 mL | 1.6215 mL | |
| 40 mM | 0.0486 mL | 0.2432 mL | 0.4865 mL | 1.2161 mL | |
| 50 mM | 0.0389 mL | 0.1946 mL | 0.3892 mL | 0.9729 mL | |
| 60 mM | 0.0324 mL | 0.1622 mL | 0.3243 mL | 0.8108 mL | |
| 80 mM | 0.0243 mL | 0.1216 mL | 0.2432 mL | 0.6081 mL |
(R)-Zunsemetinib Related Classifications
HY-139553A Related Classifications
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