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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
441 Results for "
proto-oncogene
" in MedChemExpress (MCE) Product Catalog:
Products (441)
441 Results for "proto-oncogene" in MCE Product Catalog:
89
89 Publications Verification
Cat. No.: HY-50878A
CAS No.: 1415560-69-8
Synonyms: PF-02341066 hydrochloride
Research Areas:
Crizotinib hydrochloride (PF-02341066 hydrochloride) is an orally bioavailable, selective, and ATP-competitive dual ALK and c-Met inhibitor with IC50s of 20 and 8 nM, respectively. Crizotinib hydrochloride (PF-02341066 hydrochloride) inhibits tyrosine phosphorylation of NPM-ALK and tyrosine phosphorylation of c-Met with IC50s of 24 and 11 nM in cell-based assays, respectively. It is also a ROS proto-oncogene 1 (ROS1) inhibitor. Crizotinib hydrochloride (PF-02341066 hydrochloride) has effective tumor growth inhibition .
34
34 Cited Publications
Synonyms: RR82 hydrochloride
Research Areas:
Pyridostatin (RR82) hydrochloride is a G-quadruplex DNA stabilizing agent (Kd=490 nM) and can target DNA and RNA G4s in cells. Pyridostatin hydrochloride promotes growth arrest in human cancer cells by inducing replication- and transcription-dependent DNA damage. Pyridostatin hydrochloride targets the proto-oncogene Src. Pyridostatin hydrochloride reduced SRC protein levels and SRC-dependent cellular motility in human breast cancer cells .
27
27 Cited Publications
Cat. No.: HY-N6732
CAS No.: 99533-80-9
Synonyms: SF2370; Antibiotic K 252a; Antibiotic SF 2370
Target:
7
4
4
4 Cited Publications
Cat. No.: HY-P80276
Synonyms: AKT 1 antibody; AKT antibody; AKT1 antibody; AKT1_HUMAN antibody; MGC99656 antibody; PKB antibody; PKB-ALPHA antibody; PRKBA antibody; Protein Kinase B Alpha antibody; Protein kinase B antibody; proto-oncogene c-Akt antibody; RAC Alpha antibody; RAC antibody; RAC-alpha serine/threonine-protein kinase antibody; RAC-PK-alpha antibody;
2
2
2
2
2 Cited Publications
Cat. No.: HY-P80619
Synonyms: KIT; SCFR; Mast/stem cell growth factor receptor Kit; SCFR; Piebald trait protein; PBT; proto-oncogene c-Kit; Tyrosine-protein kinase Kit; p145 c-kit; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; CD antigen CD117
1
1
1
1 Cited Publications
Cat. No.: HY-P73486
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: YES1; YES proto‑oncogene 1; Src Family Tyrosine Kinase; HsT441; C‑Yes; Yes; V‑Yes‑1 Yamaguchi Sarcoma Viral oncogene Homolog 1; Tyrosine‑Protein Kinase Yes; proto‑oncogene C‑Yes; YES1 proto‑oncogene; Src Family Tyrosine Kinase; proto‑oncogene Tyrosine‑Pro
Species:
Source:
1
1 Cited Publications
Cat. No.: HY-P701745
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: PIM1; proto-oncogene Serine/Threonine-Protein Kinase Pim-1; Prev. PIM; Pim-1 oncogene; Serine/Threonine-Protein Kinase Pim-1; oncogene PIM1; Pim-1 proto-oncogene, Serine/Threonine Kinase; Pim-1 oncogene (Proviral Integration Site 1)
1
1 Cited Publications
Cat. No.: HY-P704066
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: MYC; V-Myc Myelocytomatosis Viral oncogene Homolog; MYC proto-oncogene, BHLH Transcription Factor; Class E Basic Helix-Loop-Helix Protein 39; BHLHe39; MRTL; Myc proto-oncogene Protein; V-Myc Myelocytomatosis Viral oncogene Homolog (Avian), Isoform CRA_b;
1
1 Cited Publications
Cat. No.: HY-P701321
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: SRC; Tyrosine Kinase Pp60c-Src; Prev. SRC1; P60-Src; C-Src; protooncogene SRC, Rous Sarcoma; ASV; Tyrosine-Protein Kinase SRC-1; V-Src Avian Sarcoma (Schmidt-Ruppin A-2) Viral oncogene Homolog; Pp60c-Src; proto-oncogene Tyrosine-Protein Kinase Src; THC6;
1
1 Cited Publications
Cat. No.: HY-P72948
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CSF1R; CSF-1R; Prev. FMS; Macrophage Colony Stimulating Factor I Receptor; C-FMS; Colony Stimulating Factor Receptor; CD115; Receptor Protein-Tyrosine Kinase; CSFR; FMS proto-oncogene; McDonough Feline Sarcoma Viral (V-Fms) oncogene Homolog; BANDDOS; Macr
1
1 Cited Publications
Cat. No.: HY-P700065AF
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FGF3; Heparin-Binding Growth Factor 3; Prev. INT2; proto-oncogene Int-2; HBGF-3; oncogene INT2; Fibroblast Growth Factor 3 (Murine Mammary Tumor Virus Integration Site (V-Int-2) oncogene Homolog); FGF-3; V-INT2 Murine Mammary Tumor Virus Integration Site
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
