JunD Antibody (YA9719)
(Synonyms: Activator protein 1, AP 1, AP1, Jun D, jun D proto oncogene, Jund, JunD FL isoform, JUND_HUMAN, Transcription factor jun D, Transcription factor jun-D)JunD Antibody (YA9719) is a Rabbit-derived and non-conjugated IgG Recombinant,Monoclonal antibody, targeting to JunD.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, ICC/IF, IF-Tissue, IP, IHC-P, FC
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Reactivity :
Human
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Formulation:
Supplied in TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
IF-Tissue
IF-Tissue: Immunofluorescence-Tissue
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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IP
IP: Immunoprecipitation
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FC
FC: Flow Cytometry
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|---|---|---|---|---|---|---|
| Dilution Ratio | 1:1000-2000 | 1:100 | 1:50-200 | 1:500 | 1-2μg/sample | 1:1000 |
Product Details
JunD Antibody (YA9719) is a Rabbit-derived and non-conjugated IgG Recombinant,Monoclonal antibody, targeting to JunD.
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Host Rabbit
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Clonality Recombinant,Monoclonal
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Species ReactivityHuman
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Calculated Molecular Weight Predicted band size: 35 kDa;
Recombinant protein of Human JunD (aa 101-200).
Endogenous
affinity purified.
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
JunD transcription factor binding AP-1 sites. Heterodimerizes with proteins of the FOS family to form an AP-1 transcription factor complex, thereby enhancing their DNA binding activity to an AP-1 consensus sequence 3'-TGA[GC]TCA-5' and enhancing their transcriptional activity[1][2].
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Subcellular Localization
Nucleus
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Subunit
Heterodimer; binds DNA as a heterodimer (PubMed:28981703). Component of an AP-1 transcription factor complex composed of JUN-FOS heterodimers (By similarity). As part of the AP-1 transcription factor complex, forms heterodimers with FOS proteins, thereby binding to the AP-1 consensus sequence and stimulating transcription (By similarity). Forms heterodimers with FOSB; thereby binding to the AP-1 consensus sequence (PubMed:28981703). Interacts (via MBM motif) with MEN1; this interaction represses transcriptional activation (PubMed:22327296, PubMed:9989505). Interacts with MAPK10; this interaction is inhibited in the presence of MEN1 (PubMed:22327296)
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SwissProt ID
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Synonyms
Activator protein 1, AP 1, AP1, Jun D, jun D proto oncogene, Jund, JunD FL isoform, JUND_HUMAN, Transcription factor jun D, Transcription factor jun-D
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