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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
193 Results for "
MC-Gly-Gly-{D-Phe}-Gly-NH-CH2-O-CH2COOH
" in MedChemExpress (MCE) Product Catalog:
Products (193)
193 Results for "MC-Gly-Gly-{D-Phe}-Gly-NH-CH2-O-CH2COOH" in MCE Product Catalog:
Cat. No.: HY-131990A
CAS No.: 1802520-40-6
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MC-Gly-Gly-{D-Phe}-Gly-NH-CH2-O-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
17
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Cardiovascular Disease Inflammation/Immunology Endocrinology Cancer
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Cardiovascular Disease Inflammation/Immunology Endocrinology Cancer
16
16 Cited Publications
Cat. No.: HY-P0210
CAS No.: 78123-71-4
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16 Cited Publications
Cat. No.: HY-P0210B
CAS No.: 950492-85-0
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11
11 Cited Publications
Cat. No.: HY-P1929
CAS No.: 128270-60-0
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11
11 Cited Publications
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8
8 Cited Publications
Cat. No.: HY-19870
CAS No.: 920014-72-8
Synonyms: RM-493; BIM-22493; IRC-022493
Target:
Setmelanotide (RM-493) is a blood-brain barrier-permeable, selective MC4R agonist with a Ki value of 2.1 nM for hMC4R. Setmelanotide activates the CaMKK2/AMPK signaling pathway. Setmelanotide mediates body weight homeostasis, feeding regulation and energy expenditure modulation; it reduces food intake, induces weight loss, decreases obesity severity, increases daytime activity and energy expenditure, lowers levels of leptin, triglycerides, fasting insulin and diastolic blood pressure, improves insulin sensitivity, glucose tolerance and fatty liver condition, and reverses respiratory depression. Setmelanotide is applicable to research related to obesity, hyperinsulinemia, fatty liver and respiratory depression .
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8 Cited Publications
Cat. No.: HY-19870C
CAS No.: 2759937-80-7
Synonyms: RM-493 monoacetate; BIM-22493 monoacetate; IRC-022493 monoacetate
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Cardiovascular Disease Metabolic Disease Inflammation/Immunology
4
4 Cited Publications
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4
4 Cited Publications
Synonyms: Oxodotreotide
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4
4 Cited Publications
Synonyms: Oxodotreotide acetate
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3
3 Cited Publications
Cat. No.: HY-P0187
CAS No.: 106128-89-6
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3
3 Cited Publications
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2
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2
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Cetrorelix (SB-75) acetate is a competitive gonadotropin-releasing hormone receptor (GnRHR) antagonist with a Kd of 0.19 nM. Cetrorelix acetate inhibits the secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH), thereby suppressing the secretion of downstream sex steroids. Cetrorelix acetate prevents ovulation, induces reversible reproductive shutdown and azoospermia, reduces ovarian fibrosis, improves superovulation outcomes, and inhibits chemotherapy-induced mitochondria-dependent apoptosis. Cetrorelix acetate is applicable for fertility assistance research .
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2 Cited Publications
Cat. No.: HY-P1335
CAS No.: 103429-32-9
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2
2 Cited Publications
Cat. No.: HY-P1335A
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1
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Metabolic Disease Inflammation/Immunology Endocrinology Cancer
Melanotan I (MT-I; [Nle4,D-Phe7]-α-MSH) is an α-MSH (HY-P0252) analog, synthetic melanotropic peptide, and melanocortin receptor (MCR) agonist. Melanotan I induces skin tanning by mimicking the action of α-MSH on the melanocortin 1 receptor (MC1R) in melanocytes. As an appetite suppressant, Melanotan I impairs the ability of insulin to inhibit endogenous glucose production, suppresses leptin secretion from adipose tissue, and thereby reduces voluntary feed intake in ewes. Melanotan I can be used in research related to UV-induced skin damage, polymorphic light eruption, ruminant feeding, and sexual dysfunction .
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1 Cited Publications
Cat. No.: HY-P0267
CAS No.: 121062-08-6
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
