(D-Phe6,Leu-NHEt13,des-Met14)-Bombesin (6-14)
(D-Phe6,Leu-NHEt13,des-Met14)-Bombesin (6-14) is a bombesin (BBN) antagonist and can be used for the research of cancer.
For research use only. We do not sell to patients.
- CAS No.: 124199-90-2
- Formula: C49H69N13O9
- Molecular Weight:984.15
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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HY-P0195
BombesinBombesin Receptor Modulator -
HY-103286
PD176252BB1/BB2 Antagonist -
HY-14342
MK-5046BRS-3 Agonist -
HY-103281
LitorinBombesin Receptor Agonist -
HY-103286R
PD176252 (Standard)Reference Standard -
![[D-Phe12,Leu14]-Bombesin](https://file.medchemexpress.com/product_pic/hy-103287.gif)
HY-103287
[D-Phe12,Leu14]-BombesinBombesin Receptor Antagonist -
HY-P3112
ICI 216140GRP/Bombesin Receptor 2 Antagonist -
![[D-Phe12]-Bombesin](https://file.medchemexpress.com/product_pic/hy-103282.gif)
HY-103282
[D-Phe12]-BombesinBombesin Receptor Antagonist
Biological Activity
Description
Chemical Information
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CAS No. 124199-90-2
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Molecular Weight 984.15
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Formula C49H69N13O9
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Sequence
{d-Phe}-Gln-Trp-Ala-Val-Gly-His-{Leu-NHEt}
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Sequence Shortening
{d-Phe}-QWAVGH-{Leu-NHEt}
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent & Solubility
In Vitro
H2O
Peptide Solubility and Storage Guidelines:
1. Calculate the length of the peptide.
2. Calculate the overall charge of the entire peptide according to the following table:
| Contents | Assign value | |
|---|---|---|
| Acidic amino acid | Asp (D), Glu (E), and the C-terminal -COOH. | -1 |
| Basic amino acid | Arg (R), Lys (K), His (H), and the N-terminal -NH2 | +1 |
| Neutral amino acid | Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) | 0 |
3. Recommended solution:
| Overall charge of peptide | Details |
|---|---|
| Negative (<0) |
1. Try to dissolve the peptide in water first. 2. If water fails, add NH4OH (<50 μL). 3. If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide. |
| Positive (>0) |
1. Try to dissolve the peptide in water first. 2. If water fails, try dissolving the peptide in a 10%-30% acetic acid solution. 3. If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO. |
| Zero (=0) |
1. Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first. 2. For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration. |
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
(D-Phe6,Leu-NHEt13,des-Met14)-Bombesin (6-14) Related Classifications
HY-P4541 Related Classifications
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