NOTA-IMB-RGD
NOTA-IMB-RGD is a dual molecular probe targeting integrin αvβ3 and programmed death ligand-1 (PD-L1). NOTA-IMB-RGD blocks the PD-1/PD-L1 signaling pathway and integrin αvβ3-overexpressing tumor vasculature. NOTA-IMB-RGD is promising for research of solid tumors co-expressing PD-L1 and αvβ3 (e.g., glioma, breast cancer).
For research use only. We do not sell to patients.
- Formula: C118H196N30O37S
- Molecular Weight:2659.06
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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Molecular Weight 2659.06
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Formula C118H196N30O37S
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Sequence
NOTA-{5-AVA}-{Lys(AEEA-Suc-cyclo(Arg-Gly-Asp-{d-Phe}-Lys))}-Leu-Thr-Cys-Ser-Leu-Ala-Pro-Asn-Ile-Ile-Ser-Ala-Leu
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Sequence Shortening
NOTA-{5-AVA}-{Lys(AEEA-Suc-cyclo(RGD-{d-Phe}-K))}-LTCSLAPNIISAL
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)