1. GPCR/G Protein
    Neuronal Signaling
  2. Melanocortin Receptor
  3. Setmelanotide TFA

Setmelanotide TFA (Synonyms: RM-493 (TFA); BIM-22493 (TFA); IRC-022493 (TFA))

Cat. No.: HY-19870A
Handling Instructions

Setmelanotide TFA (RM-493 TFA; BIM-22493 TFA; IRC-022493 TFA) is a selective melanocortin 4 receptor (MC4R) agonist with EC50s of 0.27 nM and 0.28 nM for human and rat MC4R, respectively.

For research use only. We do not sell to patients.

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Setmelanotide TFA Chemical Structure

Setmelanotide TFA Chemical Structure

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Description

Setmelanotide TFA (RM-493 TFA; BIM-22493 TFA; IRC-022493 TFA) is a selective melanocortin 4 receptor (MC4R) agonist with EC50s of 0.27 nM and 0.28 nM for human and rat MC4R, respectively[1].

IC50 & Target

EC50: 5.8 nM (hMC1R), 5.3 nM (hMC3R), 0.27 nM (hMC4R), 0.28 nM (rMC4R), 1600 nM (hMC5R)[1]
Ki:3.9 nM (hMC1R), 10 nM (hMC3R), 2.1 nM (hMC4R), 430 nM (hMC5R), 2.7 nM (rMC4R)[1]

Molecular Weight

1231.33

Formula

C₅₁H₆₉F₃N₁₈O₁₁S₂

Shipping

Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Setmelanotide TFA
Cat. No.:
HY-19870A
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