Stressin I
Based on 1 publication(s) in Google Scholar
Stressin I (Cyclo(31-34)[DPhe12,Nle21,38,Glu31,Lys34]Ac-hCRF(4-41)) is a potent CRF1 receptor-selective agonist with a Ki of 1.7 nM. Stressin I induces increases in adrenocorticotropic hormone (ACTH) levels in rats.
For research use only. We do not sell to patients.
- Purity: 98.85%
- Formula: C203H337N57O56
- Molecular Weight:4472.20
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Storage:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) Stressin I
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Biological Activity
Ki: 1.7 nM (CRF1), 222 nM (CRF2)[1]
Chemical Information
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Appearance Solid
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Molecular Weight 4472.20
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Formula C203H337N57O56
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Color White to off-white
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Synonyms
Cyclo(31-34)[DPhe12,Nle21,38,Glu31,Lys34]Ac-hCRF(4-41)
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Sequence
Ac-Pro-Pro-Ile-Ser-Leu-Asp-Leu-Thr-{d-Phe}-His-Leu-Leu-Arg-Glu-Val-Leu-Glu-{Nle}-Ala-Arg-Ala-Glu-Gln-Leu-Ala-Gln-Gln-Glu-His-Ser-Lys-Arg-Lys-Leu-{Nle}-Glu-Ile-Ile-NH2 (Covalent bond: Glu28-Lys31)
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Sequence Shortening
Ac-PPISLDLT-{d-Phe}-HLLREVLE-{Nle}-ARAEQLAQQEHSKRKL-{Nle}-EII-NH2 (Covalent bond: Glu28-Lys31)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Publications (1)
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Journal Impact Factor
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Most Recent
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J Agric Food Chem
Peoniflorin Alleviates Corticotropin-Releasing Factor-Induced Irritable Bowel Syndrome by Improving the Intestinal Barrier Function through the Inhibition of the CRFR1/ROCK2/MLC Signaling Pathway. [Abstract]2026 Jan 28;74(3):2560-2573. PMID: 41550014
Solvent & Solubility
DMSO : 100 mg/mL (22.36 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (289 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.2236 mL | 1.1180 mL | 2.2360 mL | 5.5901 mL |
| 5 mM | 0.0447 mL | 0.2236 mL | 0.4472 mL | 1.1180 mL | |
| 10 mM | 0.0224 mL | 0.1118 mL | 0.2236 mL | 0.5590 mL | |
| 15 mM | 0.0149 mL | 0.0745 mL | 0.1491 mL | 0.3727 mL | |
| 20 mM | 0.0112 mL | 0.0559 mL | 0.1118 mL | 0.2795 mL |
Stressin I Related Classifications
HY-P1368 Related Classifications
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