Stressin I TFA
Based on 1 publication(s) in Google Scholar
Stressin I (Cyclo(31-34)[DPhe12,Nle21,38,Glu31,Lys34]Ac-hCRF(4-41)) TFA is a potent CRF1 receptor selective agonist, Ki is 1.7 nM. Stressin I induces an increase in adrenocorticotropic hormone (ACTH) levels in rats.
For research use only. We do not sell to patients.
- Purity: 98.63%
- Formula: C203H337N57O56.xC2HF3O2
- Molecular Weight:4472.20 (free base)
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Storage:
Sealed storage, away from moisture and light.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Publications Citing Use of MedChemExpress (MCE) Stressin I TFA
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Biological Activity
CRF1
Chemical Information
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Appearance Solid
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Molecular Weight 4472.20 (free base)
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Formula C203H337N57O56.xC2HF3O2
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Color White to off-white
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Synonyms
Cyclo(31-34)[DPhe12,Nle21,38,Glu31,Lys34]Ac-hCRF(4-41) TFA
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Sequence
Ac-Pro-Pro-Ile-Ser-Leu-Asp-Leu-Thr-{d-Phe}-His-Leu-Leu-Arg-Glu-Val-Leu-Glu-Nle-Ala-Arg-Ala-Glu-Gln-Leu-Ala-Gln-Gln-Glu-His-Ser-Lys-Arg-Lys-Leu-{Nle}-Glu-Ile-Ile-NH2 (Covalent bond: Glu28-Lys31)
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Sequence Shortening
Ac-PPISLDLT-{d-Phe}-HLLREVLE-{Nle}-ARAEQLAQQEHSKRKL-{Nle}-EII-NH2 (Covalent bond: Glu28-Lys31)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Sealed storage, away from moisture and light
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Publications (1)
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Journal Impact Factor
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Most Recent
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J Agric Food Chem
Peoniflorin Alleviates Corticotropin-Releasing Factor-Induced Irritable Bowel Syndrome by Improving the Intestinal Barrier Function through the Inhibition of the CRFR1/ROCK2/MLC Signaling Pathway. [Abstract]2026 Jan 28;74(3):2560-2573. PMID: 41550014
Solvent & Solubility
H2O : 1.98 mg/mL (ultrasonic and adjust pH to 3 with HCl)
Purity & Documentation
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Data Sheet (287 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)