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  2. Drug Derivative Biochemical Assay Reagents
  3. DBCO-cyclo(RGDfK)

DBCO-cyclo(RGDfK) is a clickable RGD peptide and DBCO derivative of cyclo(RGDfK) (HY-P0023).

For research use only. We do not sell to patients.

Custom Peptide Synthesis

DBCO-cyclo(RGDfK)

DBCO-cyclo(RGDfK) Chemical Structure

CAS No. : 2425606-55-7

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Based on 1 publication(s) in Google Scholar

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  • Biological Activity

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Description

DBCO-cyclo(RGDfK) is a clickable RGD peptide and DBCO derivative of cyclo(RGDfK) (HY-P0023)[1].

Molecular Weight

890.98

Formula

C46H54N10O9

CAS No.
Appearance

Solid

Color

White to off-white

Sequence

DBCO-cyclo(Arg-Gly-Asp-{d-Phe}-Lys)

Sequence Shortening

DBCO-cyclo(RGD-{d-Phe}-K)

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (56.12 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.1224 mL 5.6118 mL 11.2236 mL
5 mM 0.2245 mL 1.1224 mL 2.2447 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.1224 mL 5.6118 mL 11.2236 mL 28.0590 mL
5 mM 0.2245 mL 1.1224 mL 2.2447 mL 5.6118 mL
10 mM 0.1122 mL 0.5612 mL 1.1224 mL 2.8059 mL
15 mM 0.0748 mL 0.3741 mL 0.7482 mL 1.8706 mL
20 mM 0.0561 mL 0.2806 mL 0.5612 mL 1.4029 mL
25 mM 0.0449 mL 0.2245 mL 0.4489 mL 1.1224 mL
30 mM 0.0374 mL 0.1871 mL 0.3741 mL 0.9353 mL
40 mM 0.0281 mL 0.1403 mL 0.2806 mL 0.7015 mL
50 mM 0.0224 mL 0.1122 mL 0.2245 mL 0.5612 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
DBCO-cyclo(RGDfK)
Cat. No.:
HY-P11428
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