DBCO-cyclo(RGDfK)
Based on 1 Customer Validation
DBCO-cyclo (RGDfK) is a clickable DBCO-modified cyclic RGD peptide, and also a DBCO derivative of cyclo (RGDfK) (HY-P0023). DBCO-cyclo (RGDfK) is synthesized via an amide coupling reaction between DBCO-NHS ester and cyclo (RGDfK). DBCO-cyclo (RGDfK) can react with azide groups through copper-free click chemistry (SPAAC) to immobilize RGD peptides onto biomaterials or hydrogels. The RGD sequence in DBCO-cyclo (RGDfK) is recognizable by cellular integrins and promotes cell adhesion. DBCO-cyclo (RGDfK) can be used in studies related to tissue engineering, 3D cell culture, and surface functionalization of biomaterials.
For research use only. We do not sell to patients.
- Purity: 99.19%
- CAS No.: 2425606-55-7
- Formula: C46H54N10O9
- Molecular Weight:890.98
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Storage:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
DBCO-cyclo (RGDfK) can react with azide groups in FEFEFKFK peptide hydrogels via SPAAC click chemistry to achieve covalent immobilization of RGD functional groups, without compromising the structural stiffness of the hydrogel[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2425606-55-7
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Appearance Solid
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Molecular Weight 890.98
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Formula C46H54N10O9
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Color White to off-white
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Sequence
DBCO-cyclo(Arg-Gly-Asp-{d-Phe}-Lys)
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Sequence Shortening
DBCO-cyclo(RGD-{d-Phe}-K)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : 50 mg/mL (56.12 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (279 KB)
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SDS (254 KB)
- English - EN (254 KB)
- Français - FR (254 KB)
- Deutsch - DE (254 KB)
- Norwegian - NO (254 KB)
- Español - ES (254 KB)
- Swedish - SV (254 KB)
- Italian - IT (254 KB)
- Korean - KR (254 KB)
- Portuguese - PT (254 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.1224 mL | 5.6118 mL | 11.2236 mL | 28.0590 mL |
| 5 mM | 0.2245 mL | 1.1224 mL | 2.2447 mL | 5.6118 mL | |
| 10 mM | 0.1122 mL | 0.5612 mL | 1.1224 mL | 2.8059 mL | |
| 15 mM | 0.0748 mL | 0.3741 mL | 0.7482 mL | 1.8706 mL | |
| 20 mM | 0.0561 mL | 0.2806 mL | 0.5612 mL | 1.4029 mL | |
| 25 mM | 0.0449 mL | 0.2245 mL | 0.4489 mL | 1.1224 mL | |
| 30 mM | 0.0374 mL | 0.1871 mL | 0.3741 mL | 0.9353 mL | |
| 40 mM | 0.0281 mL | 0.1403 mL | 0.2806 mL | 0.7015 mL | |
| 50 mM | 0.0224 mL | 0.1122 mL | 0.2245 mL | 0.5612 mL |
DBCO-cyclo(RGDfK) Related Classifications
HY-P11428 Related Classifications
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