2425606-55-7
Chemical Structure
DBCO-cyclo(RGDfK)
- CAS No.: 2425606-55-7
- Formula:C46H54N10O9
- Molecular Weight:890.98
InChIKey: BUILTWQDSWZSCV-KFIZHRIMSA-N
SMILES: NC(NCCC[C@@H]1NC([C@@H](NC([C@H](NC([C@@H](NC(CNC1=O)=O)CC(O)=O)=O)CC2=CC=CC=C2)=O)CCCCNC(CCC(N3CC4=C(C=CC=C4)C#CC5=C3C=CC=C5)=O)=O)=O)=N
Biological Activity: DBCO-cyclo (RGDfK) is a clickable DBCO-modified cyclic RGD peptide, and also a DBCO derivative of cyclo (RGDfK) (HY-P0023). DBCO-cyclo (RGDfK) is synthesized via an amide coupling reaction between DBCO-NHS ester and cyclo (RGDfK). DBCO-cyclo (RGDfK) can react with azide groups through copper-free click chemistry (SPAAC) to immobilize RGD peptides onto biomaterials or hydrogels. The RGD sequence in DBCO-cyclo (RGDfK) is recognizable by cellular integrins and promotes cell adhesion. DBCO-cyclo (RGDfK) can be used in studies related to tissue engineering, 3D cell culture, and surface functionalization of biomaterials[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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DBCO-cyclo(RGDfK) | 99.19% | DBCO-cyclo (RGDfK) is a clickable DBCO-modified cyclic RGD peptide, and also a DBCO derivative of cyclo (RGDfK) (HY-P0023). DBCO-cyclo (RGDfK) is synthesized via an amide coupling reaction between DBCO-NHS ester and cyclo (RGDfK). DBCO-cyclo (RGDfK) can react with azide groups through copper-free click chemistry (SPAAC) to immobilize RGD peptides onto biomaterials or hydrogels. The RGD sequence in DBCO-cyclo (RGDfK) is recognizable by cellular integrins and promotes cell adhesion. DBCO-cyclo (RGDfK) can be used in studies related to tissue engineering, 3D cell culture, and surface functionalization of biomaterials. | ||||||||||||||||||||
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