Acetyl hexapeptide-1
Based on 1 Customer Validation
Acetyl hexapeptide-1 (Melitane) is a biomimetic peptide that mimics the activity of α-melanocyte-stimulating hormone (α-MSH). Acetyl hexapeptide-1 regulates muscle contraction, thereby reducing facial expression lines. Acetyl hexapeptide-1 is one of the components of anti-aging skincare serums targeting dynamic wrinkles. Acetyl hexapeptide-1 can be used in research related to mild photoaged facial skin and premature gray hair.
For research use only. We do not sell to patients.
- Purity: 99.43%
- CAS No.: 448944-47-6
- Formula: C43H59N13O7
- Molecular Weight:870.01
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Storage:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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GPCR/G Protein Compound Library
HY-L006
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Neuronal Signaling Compound Library
HY-L013
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Anti-Aging Compound Library
HY-L034
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Peptide Library
HY-L105
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Membrane Protein-targeted Compound Library
HY-L149
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Membrane Receptor-targeted Compound Library
HY-L150
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Bioactive Compound Library Max
HY-L181
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MCE Bioactive Compound Library
HY-L001V
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Peptide Compound Library
HY-L105S
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Bioactive Compound Library
HY-L001
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High-Throughput Bioactive Compound Library
HY-L205
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Cosmetic Ingredient Compound Library
HY-L221
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Lactylation Compound Library
HY-L249
Biological Activity
Acetyl hexapeptide-1 acts directly on melanocytes in hair follicles to promote hair repigmentation. In skin care products, it is used to induce healthy skin pigmentation, helping to improve uneven skin tone and local paleness. Acetyl hexapeptide-1 also reduces skin erythema and inflammatory responses, and helps repair UV-induced DNA damage, making the skin appear healthier[1][2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 448944-47-6
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Appearance Solid
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Molecular Weight 870.01
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Formula C43H59N13O7
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Color White to off-white
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Synonyms
Melitane
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Sequence
Ac-{Nle}-Ala-His-{d-Phe}-Arg-Trp-NH2
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Sequence Shortening
Ac-{Nle}-AH-{d-Phe}-RW-NH2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
H2O : 25 mg/mL (28.74 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (275 KB)
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SDS (254 KB)
- English - EN (254 KB)
- Français - FR (254 KB)
- Deutsch - DE (254 KB)
- Norwegian - NO (254 KB)
- Español - ES (254 KB)
- Swedish - SV (254 KB)
- Italian - IT (254 KB)
- Korean - KR (254 KB)
- Portuguese - PT (254 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 1.1494 mL | 5.7471 mL | 11.4941 mL | 28.7353 mL |
| 5 mM | 0.2299 mL | 1.1494 mL | 2.2988 mL | 5.7471 mL | |
| 10 mM | 0.1149 mL | 0.5747 mL | 1.1494 mL | 2.8735 mL | |
| 15 mM | 0.0766 mL | 0.3831 mL | 0.7663 mL | 1.9157 mL | |
| 20 mM | 0.0575 mL | 0.2874 mL | 0.5747 mL | 1.4368 mL | |
| 25 mM | 0.0460 mL | 0.2299 mL | 0.4598 mL | 1.1494 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Acetyl hexapeptide-1 Related Classifications
HY-P5220 Related Classifications
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