RI-OR2-TAT
RI-OR2-TAT is a brain-penetrant inhibitor of β-Amyloid oligomerization, which is produced by adding the HIV protein transduction domain TAT to RI-OR2. RI-OR2-TAT binds to Aβ42 fibrils with a Kd value of 58-125 nM. RI-OR2-TAT reduces Aβ aggregation and plaque levels, reduces activation of microglia and oxidative damage, and increases the number of young neurons in the dentate gyrus.
For research use only. We do not sell to patients.
- CAS No.: 1430219-69-4
- Formula: C117H201N49O23
- Molecular Weight:2662.16
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 1430219-69-4
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Molecular Weight 2662.16
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Formula C117H201N49O23
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Sequence
Ac-{d-Arg}-Gly-{d-Phe}-{d-Phe}-{d-Val}-{d-Leu}-{d-Lys}-Gly-{d-Arg}-{d-Arg}-{d-Arg}-{d-Arg}-{d-Gln}-{d-Arg}-{d-Arg}-{d-Lys}-{d-Lys}-{d-Arg}-Gly-{d-Tyr}-NH2
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Sequence Shortening
Ac-{d-Arg}-G-{d-Phe}-{d-Phe}-{d-Val}-{d-Leu}-{d-Lys}-G-{d-Arg}-{d-Arg}-{d-Arg}-{d-Arg}-{d-Gln}-{d-Arg}-{d-Arg}-{d-Lys}-{d-Lys}-{d-Arg}-Gly-{d-Tyr}-NH2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
RI-OR2-TAT Related Classifications
HY-P10824 Related Classifications
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