RI-OR2-TAT
RI-OR2-TAT is a brain-penetrant inhibitor of β-Amyloid oligomerization, which is produced by adding the HIV protein transduction domain TAT to RI-OR2. RI-OR2-TAT binds to Aβ42 fibrils with a Kd value of 58-125 nM. RI-OR2-TAT reduces Aβ aggregation and plaque levels, reduces activation of microglia and oxidative damage, and increases the number of young neurons in the dentate gyrus.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- CAS No.: 1430219-69-4
- 화학식: C117H201N49O23
- 분자량:2662.16
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 1430219-69-4
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분자량 2662.16
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화학식 C117H201N49O23
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Sequence
Ac-{d-Arg}-Gly-{d-Phe}-{d-Phe}-{d-Val}-{d-Leu}-{d-Lys}-Gly-{d-Arg}-{d-Arg}-{d-Arg}-{d-Arg}-{d-Gln}-{d-Arg}-{d-Arg}-{d-Lys}-{d-Lys}-{d-Arg}-Gly-{d-Tyr}-NH2
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Sequence Shortening
Ac-{d-Arg}-G-{d-Phe}-{d-Phe}-{d-Val}-{d-Leu}-{d-Lys}-G-{d-Arg}-{d-Arg}-{d-Arg}-{d-Arg}-{d-Gln}-{d-Arg}-{d-Arg}-{d-Lys}-{d-Lys}-{d-Arg}-Gly-{d-Tyr}-NH2
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
RI-OR2-TAT Related Classifications
HY-P10824 Related Classifications
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