Search Result

Results for "

Protein kinase B

" in MCE Product Catalog:

By Targets:	AAK1 (2) Akt (4) Anaplastic lymphoma kinase (ALK) (1) Apoptosis (6) Aurora Kinase (2) Bacterial (2) Bcr-Abl (1) CaMK (1) CDK (8) COX (2) Cyclin G-associated Kinase (GAK) (2) EGFR (1) Endogenous Metabolite (3) ERK (1) Ferroptosis (2) FLT3 (1) GSK-3 (1) JAK (1) LIM Kinase (LIMK) (3) MAP4K (1) MAPKAPK2 (MK2) (1) MEK (1) NF-κB (2) NO Synthase (1) Orthopoxvirus (3) Parasite (1) Phosphatase (1) PKC (3) PROTACs (4) Raf (2) ROCK (1) Salt-inducible Kinase (SIK) (3) STAT (2) TOPK (1) Topoisomerase (3) Trk Receptor (1) ULK (2) Wee1 (2)
By Research Areas:	Cancer (20) Cardiovascular Disease (1) Infection (6) Inflammation/Immunology (3) Neurological Disease (1)

By Targets:

AAK1 (2)

Akt (4)

Anaplastic lymphoma kinase (ALK) (1)

Apoptosis (6)

Aurora Kinase (2)

Bacterial (2)

Bcr-Abl (1)

CaMK (1)

CDK (8)

COX (2)

Cyclin G-associated Kinase (GAK) (2)

EGFR (1)

Endogenous Metabolite (3)

ERK (1)

Ferroptosis (2)

FLT3 (1)

GSK-3 (1)

JAK (1)

LIM Kinase (LIMK) (3)

MAP4K (1)

MAPKAPK2 (MK2) (1)

MEK (1)

NF-κB (2)

NO Synthase (1)

Orthopoxvirus (3)

Parasite (1)

Phosphatase (1)

PKC (3)

PROTACs (4)

Raf (2)

ROCK (1)

Salt-inducible Kinase (SIK) (3)

STAT (2)

TOPK (1)

Topoisomerase (3)

Trk Receptor (1)

ULK (2)

Wee1 (2)

By Research Areas:

Cancer (20)

Cardiovascular Disease (1)

Infection (6)

Inflammation/Immunology (3)

Neurological Disease (1)

Inhibitors & Agonists

Screening Libraries

Natural
Products

Recombinant Proteins

Antibodies

Cat. No.	Product Name	Target	Research Areas

HY-136219

Protein kinase affinity probe 1	Others	Others
Protein kinase affinity probe 1 is a novel protein kinase affinity probe for the functional identification of protein kinases (PKs). Protein kinase affinity probe 1 is a modified Purvalanol B (HY-18299) probe with 50% beads loading (Compound S3).

HY-143611

AKT-IN-8

Akt Cancer

AKT-IN-8 is a potent AKT inhibitor with IC₅₀s of 4.46, 2.44, and 9.47 nM for AKT1, AKT2, and AKT3, respectively.
HY-151206

PknB-IN-2

Bacterial Infection

PknB-IN-2 (Compound 10) is a Mycobacterium tuberculosis protein kinase B (PknB) inhibitor with an IC₅₀ of 12.1 μM.
HY-143882

MS5033

PROTACs Akt Cancer

MS5033 is a potent PROTAC-based AKT (protein kinase B) degrader, with a DC₅₀ of 430 nM in PC3 cells.

AKT-IN-8	Akt	Cancer
AKT-IN-8 is a potent AKT inhibitor with IC₅₀s of 4.46, 2.44, and 9.47 nM for AKT1, AKT2, and AKT3, respectively.

PknB-IN-2	Bacterial	Infection
PknB-IN-2 (Compound 10) is a Mycobacterium tuberculosis protein kinase B (PknB) inhibitor with an IC₅₀ of 12.1 μM.

MS5033	PROTACs Akt	Cancer
MS5033 is a potent PROTAC-based *AKT (protein* kinase B)** degrader, with a DC₅₀ of 430 nM in PC3 cells.

HY-N0811

Anemarsaponin B	NO Synthase COX NF-κB MEK	Inflammation/Immunology
Anemarsaponin B is a steroidal saponin. Anemarsaponin B decreases the protein and mRNA levels of iNOS and COX-2. Anemarsaponin B reduces the expressions and productions of pro-inflammatory cytokines, including TNF-a and IL-6. Anemarsaponin B inhibits the nuclear translocation of the p65 subunit of NF-κB by blocking the phosphorylation of IκBα. Anemarsaponin B also inhibits the phosphorylation of MAP kinase kinases 3/6 (MKK3/6) and mixed lineage kinase 3 (MLK3). Anti-inflammatory effect .

HY-130517

Cdc7-IN-5	CDK	Cancer
Cdc7-IN-5 (compound I-B) is a potent Cdc7 kinase inhibitor extracted from patent WO2019165473A1, compound I-B. Cdc7 is a serine-threonine protein kinase enzyme which is essential for the initiation of DNA replication in the cell cycle.

HY-142820

B-Raf IN 5	Raf	Cancer
B-Raf IN 5 (compound 3b) is a potent inhibitor of protein kinase *B-Raf* with an IC₅₀ of 2.0 nM. B-Raf IN 5 is devoid of binding to the secondary target PXR and resists rapid metabolism. B-Raf IN 6 has the potential for the research of cancer disease.

HY-142830

B-Raf IN 6	Raf	Cancer
B-Raf IN 6 (compound 2c) is a potent inhibitor of protein kinase *B-Raf* with an IC₅₀ of 1.7 nM. B-Raf IN 6 is devoid of binding to the secondary target PXR and resists rapid metabolism. B-Raf IN 6 has the potential for the research of cancer disease.

HY-130515

Cdc7-IN-3	CDK	Cancer
Cdc7-IN-3 (compound I-A) is a potent Cdc7 kinase inhibitor extracted from patent WO2019165473A1, compound I-B. Cdc7 is a serine-threonine protein kinase enzyme which is essential for the initiation of DNA replication in the cell cycle.

HY-12467

OTS964 hydrochloride 4 Publications Verification	TOPK CDK Apoptosis	Cancer
OTS964 hydrochloride is an orally active, high affinity and selective TOPK (T-lymphokine-activated killer cell-originated protein kinase) inhibitor with an IC₅₀ of 28 nM. OTS964 hydrochloride is also a potent inhibitor of the cyclin-dependent kinase CDK11, which binds to CDK11B with a K_d of 40 nM.

HY-153011

ROCK-IN-5	ROCK ERK GSK-3	Neurological Disease Cardiovascular Disease
ROCK-IN-5 (compound I-B-37) is a potent inhibitor of ROCK, ERK, GSK, and AGC protein kinases. ROCK-IN-5 has the potential for proliferative, cardiac and neurodegenerative diseases research.

HY-N9561

Vanicoside B	CDK STAT	Cancer
Vanicoside B is a phenylpropanoyl sucrose derivative, can be isolated from the herb Persicaria dissitiflora. Vanicoside B targets *cyclin-dependent kinase* 8 (CDK8) and exhibits anti-tumor activity. The potential mechanism is Vanicoside B blocks CDK8*-mediated signaling pathways and decreases the expression of epithelial-mesenchymal transition proteins, so that it leads to cell cycle arrest and apoptosis*.

HY-137377

TAS-119	Aurora Kinase	Cancer
TAS-119 is a potent, selective and orally active Aurora A inhibitor with an IC₅₀ of 1.0 nM. TAS-119 shows high selectivity for Aurora A over other protein kinases, including Aurora B (IC₅₀ of 95 nM). TAS-119 has potent antitumor activites.

HY-151204

PknB-IN-1	Bacterial	Infection Inflammation/Immunology
PknB-IN-1 (Compound 2) is a protein kinase B (PknB) inhibitor (IC₅₀=14.4 μM). PknB-IN-1 shows anti-mycobacterial activity, can inhibit M. tuberculosis H37Rv strain growth (MIC=6.2 μg/mL).

HY-148063

DB0614	PROTACs AAK1 Aurora Kinase CaMK CDK Ferroptosis Salt-inducible Kinase (SIK) ULK Wee1 LIM Kinase (LIMK)	Others
DB0614 (Example 21) is a bifunctional compound targeted protein degradation of kinases. DB0614 degrades AAK1, AURKA, BMP2K, CAMKK1, CDK16, CML, CDK6, EIF2AK2, FER, GAK, LCK, LIMK2, MAP3KH, MAPK8, MAPK9, NEK9, PLK4, PTK2B, SIK2, STK17A, STK17B, ULK1, ULK3, and WEE1. DB0614 can be used for research of disease or disorder mediated by aberrant kinase activity.

HY-N3634

Corylifol C	Others	Cancer
Corylifol C is a potent **protein kinase inhibitor with IC₅₀** valueS of 8.7, 3.0, 2.1, 6.4, 4.5, 6.2, 2.3, 1.2, 5.1 μg/ml for ARK5, Aurora-A, Aurora-B, AXL, B-RAF-VE, CDK4/CycD1, TIE2, EGF-R, EPHB4, respectively.

HY-18299

Purvalanol B 1 Publications Verification NG 95	CDK Parasite	Cancer Infection
Purvalanol B (NG 95) is a potent, selective, reversible and ATP-competitive inhibitor CDK, with IC₅₀s of 6 nM, 6 nM, 9 nM, 6 nM for cdc2-cyclin B, CDK2-cyclin A, CDK2-cyclin E and CDK5-p35, respectively. Purvalanol B shows selectivity for CDK over a range of other protein kinases (IC₅₀>1000 nM). Purvalanol B inhibits the growth a chloroquine-resistant strain of P. falciparum.

HY-13502B

Mitoxantrone diacetate Mitozantrone diacetate; NSC 301739 diacetate	Topoisomerase PKC Orthopoxvirus Apoptosis Endogenous Metabolite	Cancer Infection
Mitoxantrone diacetate is a potent topoisomerase II inhibitor. Mitoxantrone diacetate also inhibits protein kinase C (PKC) activity with an IC₅₀ of 8.5 μM. Mitoxantrone diacetate induces apoptosis of B-CLL (B-chronic lymphocytic leukaemia) cells. Mitoxantrone diacetate shows antitumor activity. Mitoxantrone diacetate also has anti-orthopoxvirus activity with EC₅₀s of 0.25 μM and and 0.8 μM for cowpox and monkeypox, respectively.

HY-13502

Mitoxantrone Maximum Cited Publications 15 Publications Verification Mitozantrone; NSC 301739	Topoisomerase PKC Orthopoxvirus Apoptosis Endogenous Metabolite	Cancer Infection
Mitoxantrone is a potent topoisomerase II inhibitor. Mitoxantrone also inhibits protein kinase C (PKC) activity with an IC₅₀ of 8.5 μM. Mitoxantrone induces apoptosis of B-CLL (B-chronic lymphocytic leukaemia) cells. Mitoxantrone shows antitumor activity. Mitoxantrone also has anti-orthopoxvirus activity with EC₅₀s of 0.25 μM and and 0.8 μM for cowpox and monkeypox, respectively.

HY-13502A

Mitoxantrone dihydrochloride Maximum Cited Publications 15 Publications Verification Mitozantrone dihydrochloride; NSC 301739 dihydrochloride	Topoisomerase PKC Orthopoxvirus Apoptosis Endogenous Metabolite	Cancer Infection
Mitoxantrone dihydrochloride is a potent topoisomerase II inhibitor. Mitoxantrone dihydrochloride also inhibits protein kinase C (PKC) activity with an IC₅₀ of 8.5 μM. Mitoxantrone dihydrochloride induces apoptosis of B-CLL (B-chronic lymphocytic leukaemia) cells. Mitoxantrone dihydrochloride shows antitumor activity. Mitoxantrone dihydrochloride also has anti-orthopoxvirus activity with EC₅₀s of 0.25 μM and and 0.8 μM for cowpox and monkeypox, respectively.

HY-148234

M4K2234	Anaplastic lymphoma kinase (ALK)	Cancer
M4K2234 (compound 26b) is an ALK2 inhibitor. M4K2234 inhibits ALK2 and ALK5 with IC₅₀s of 5 and 2144 nM, respectively. M4K2234 can be used as a chemical probe for ALK1 and ALK2 protein kinases. M4K2234 can be used for the research of cancer.

HY-108543

NSC 95397 3 Publications Verification	Phosphatase Apoptosis	Cancer
NSC 95397 is a potent, selective Cdc25 dual specificity phosphatase inhibitor (K_i=32 nM (Cdc25A), 96 nM (Cdc25B), 40 nM (Cdc25C); IC₅₀=22.3 nM (human Cdc25A), 56.9 nM (human Cdc25C), 125 nM (Cdc25B)). NSC 95397 inhibits mitogen-activated protein kinase phosphatase-1 (MKP-1) and suppresses proliferation and induces apoptosis in colon cancer cells through MKP-1 and ERK1/2 pathway.

HY-144060

AKT-IN-10	Akt	Cancer
AKT-IN-10 is a potent inhibitor of AKT. Protein kinase B (PKB, also known as AKT) is central to PI3K/AKT/mTOR signaling in cells, and its function is important for cell growth, survival, differentiation and metabolism. AKT-IN-10 has the potential for the research of breast and prostate cancer (extracted from patent WO2021185238A1, compound 4).

HY-144059

AKT-IN-9	Akt	Cancer
AKT-IN-9 is a potent inhibitor of AKT. Protein kinase B (PKB, also known as AKT) is central to PI3K/AKT/mTOR signaling in cells, and its function is important for cell growth, survival, differentiation and metabolism. AKT-IN-9 has the potential for the research of breast and prostate cancer (extracted from patent WO2021185238A1, compound 1).

HY-148062

RSS0680	PROTACs CDK AAK1 Cyclin G-associated Kinase (GAK) Salt-inducible Kinase (SIK) LIM Kinase (LIMK) Wee1	Others
RSS0680 (Example 22) is a bifunctional compound targeted protein degradation of kinases. RSS0680 degrades AAK1, CDK1, CDK16, CDK2, CDK4, CDK6, EIF2AK4, GAK, LATSl, LIMK2, MAPK6, MAPKAPK5, MARK2, MARK4, MKNK2, NEK9, RPS6KB1, SIK2, SNRK, STK17A, STK17B, STK35, and WEEl. RSS0680 can be used for research of disease or disorder mediated by aberrant kinase activity.

HY-100499

Tyrphostin AG 528 Tyrphostin B66; AG 528	EGFR	Cancer
Tyrphostin AG 528 is an inhibitor of EGFR and ErbB2 with IC₅₀s of 4.9 and 2.1 μM, respectively. Tyrphostin AG 528 (Tyrphostin B66) is a protein tyrosine kinase inhibitor, with IC₅₀s of 4.9 μM for epidermal growth factor receptors (EGFR) and 2.1 μM for ErbB2. Tyrphostin AG 528 is also an anticancer agent.

HY-148061

DB1113	PROTACs Bcr-Abl CDK Salt-inducible Kinase (SIK) Cyclin G-associated Kinase (GAK) MAP4K MAPKAPK2 (MK2) Ferroptosis ULK LIM Kinase (LIMK)	Others
DB1113 (Example 24) is a bifunctional compound targeted protein degradation of kinases. DB1113 degrades ABL1, ABL2, BLK, CDK11B, CDK4, CSK, EPHA3, FER, GAK, LIMK1, MAP3K20, MAP4K1, MAP4K2, MAP4K3, MAP4K5, MAPK14, MAPK7, MAPK8, MAPK9, MAPKAPK2, MAPKAPK3, NLK, PDIK1L, PTK2B, RIPK1, RPS6KA1, RPS6KA3, SIK2, SIK3, STK35, TNK2, and ULK1. DB1113 can be used for research of disease or disorder mediated by aberrant kinase activity.

HY-50867

Lestaurtinib 2 Publications Verification CEP-701; KT-5555	JAK FLT3 Trk Receptor Apoptosis STAT	Cancer
Lestaurtinib (CEP-701) is an orally active and selective RPTKs (receptor protein tyrosine kinase) inhibitor, competitively inhibits ATP binding to the *TrkA/B/C* domain. Lestaurtinib inhibits RPTKs phosphorylation, with IC₅₀s of 2, 25 and 0.9 nM for FLT3, TrkA and JAK2, respectively. Lestaurtinib induces apoptosis and cycle arrest, also can inhibit growth of tumor.

HY-N0632

Esculentoside A 2 Publications Verification	COX NF-κB	Inflammation/Immunology
Esculentoside A (EsA), a kind of triterpene saponin isolated from roots of Phytolacca esculenta. Esculentoside A (EsA) possesses anti-inflammatory activity in acute and chronic experimental models, has selective inhibitory activity towards cyclooxygenase-2 (COX-2). Esculentoside A (EsA) suppresses inflammatory responses in LPS-induced acute lung injury (ALI) through inhibition of the nuclear factor kappa B (NF-ΚB) and mitogen activated protein kinase (MAPK) signaling pathways.

Cat. No.	Product Name

HY-L008

JAK/STAT Compound Library	369 compounds
The Janus kinase (JAK)/signal transducer and activator of transcription (STAT) pathway is central to signaling by cytokine receptors, a superfamily of more than 30 transmembrane proteins that recognize specific cytokines, and is critical in blood formation and immune response. Canonical JAK/STAT signaling begins with the association of cytokines and their corresponding transmembrane receptors. Activated JAKs then phosphorylate latent STAT monomers, leading to dimerization, nuclear translocation, and DNA binding. In mammals, there are four JAKs (JAK1, JAK2, JAK3, TYK2) and seven STATs (STAT1, STAT2, STAT3, STAT4, STAT5a, STAT5b, STAT6). Since the JAK/STAT pathway plays a major role in many fundamental processes, such as apoptosis and inflammation, dysfunctional proteins in the pathway may lead to a number of diseases. For example, alterations in JAK/STAT signalling can result in cancer and diseases affecting the immune system, such as severe combined immunodeficiency disorder (SCID). MCE provides 369 compounds that can be used in the study of the JAK/STAT signaling pathway and related diseases.

JAK/STAT Compound Library

369 compounds

The Janus kinase (JAK)/signal transducer and activator of transcription (STAT) pathway is central to signaling by cytokine receptors, a superfamily of more than 30 transmembrane proteins that recognize specific cytokines, and is critical in blood formation and immune response. Canonical JAK/STAT signaling begins with the association of cytokines and their corresponding transmembrane receptors. Activated JAKs then phosphorylate latent STAT monomers, leading to dimerization, nuclear translocation, and DNA binding. In mammals, there are four JAKs (JAK1, JAK2, JAK3, TYK2) and seven STATs (STAT1, STAT2, STAT3, STAT4, STAT5a, STAT5b, STAT6). Since the JAK/STAT pathway plays a major role in many fundamental processes, such as apoptosis and inflammation, dysfunctional proteins in the pathway may lead to a number of diseases. For example, alterations in JAK/STAT signalling can result in cancer and diseases affecting the immune system, such as severe combined immunodeficiency disorder (SCID).

MCE provides 369 compounds that can be used in the study of the JAK/STAT signaling pathway and related diseases.

Cat. No.	Product Name	Target	Category

HY-N0632

Esculentoside A 2 Publications Verification	COX NF-κB	Triterpenes Terpenoids Structural Classification Phytolacca acinosa Roxb. Plants Phytolaccaceae Source classification Inflammation/Immunology Disease Research Fields Classification of Application Fields
Esculentoside A (EsA), a kind of triterpene saponin isolated from roots of Phytolacca esculenta. Esculentoside A (EsA) possesses anti-inflammatory activity in acute and chronic experimental models, has selective inhibitory activity towards cyclooxygenase-2 (COX-2). Esculentoside A (EsA) suppresses inflammatory responses in LPS-induced acute lung injury (ALI) through inhibition of the nuclear factor kappa B (NF-ΚB) and mitogen activated protein kinase (MAPK) signaling pathways.

HY-N0811

Anemarsaponin B	NO Synthase COX NF-κB MEK	Steroids Structural Classification Anemarrhena asphodeloides Bunge Liliaceae Plants Source classification Inflammation/Immunology Disease Research Fields Classification of Application Fields
Anemarsaponin B is a steroidal saponin. Anemarsaponin B decreases the protein and mRNA levels of iNOS and COX-2. Anemarsaponin B reduces the expressions and productions of pro-inflammatory cytokines, including TNF-a and IL-6. Anemarsaponin B inhibits the nuclear translocation of the p65 subunit of NF-κB by blocking the phosphorylation of IκBα. Anemarsaponin B also inhibits the phosphorylation of MAP kinase kinases 3/6 (MKK3/6) and mixed lineage kinase 3 (MLK3). Anti-inflammatory effect .

HY-N9561

Vanicoside B	CDK STAT	Structural Classification Phenols Polyphenols Source classification Plants Polygonaceae Perilla ocimoides L.
Vanicoside B is a phenylpropanoyl sucrose derivative, can be isolated from the herb Persicaria dissitiflora. Vanicoside B targets *cyclin-dependent kinase* 8 (CDK8) and exhibits anti-tumor activity. The potential mechanism is Vanicoside B blocks CDK8*-mediated signaling pathways and decreases the expression of epithelial-mesenchymal transition proteins, so that it leads to cell cycle arrest and apoptosis*.

HY-N3634

Corylifol C	Others	Structural Classification Phenols Polyphenols Leguminosae Psoralea corylifolia L. Plants Source classification
Corylifol C is a potent **protein kinase inhibitor with IC₅₀** valueS of 8.7, 3.0, 2.1, 6.4, 4.5, 6.2, 2.3, 1.2, 5.1 μg/ml for ARK5, Aurora-A, Aurora-B, AXL, B-RAF-VE, CDK4/CycD1, TIE2, EGF-R, EPHB4, respectively.

Species:	Human (29) Mouse (9) Rat (3) E.coli (2) Cynomolgus (1)
Tag:	His (34) SUMO (2) Tag Free (1) GST (4) Fc (9) B2M (1)
Source:	HEK293 (25) P. pastoris (3) Sf9 insect cells (7) E. coli (9)

Cat. No.	Product Name	Species	Source

HY-P7897

*Creatine kinase* B-type/CKB Protein, Human (His)** rHuCreatine kinase B-type/CKB , His; B-CK; CKB; Creatine kinase BB	Human	E. coli
Creatine kinaseB-type/CKB Protein, Human (His) is the most abundant creatine kinase isoenzyme in purified brown adipocytes. CKB reversibly catalyzes the transfer of phosphate between ATP and various phosphogens.

HY-P70040

BLK Protein, Human (His)

rHuTyrosine-Protein kinase Blk/BLK, His; Tyrosine-Protein kinase Blk; B Lymphocyte kinase; p55-Blk; BLK
Human E. coli
HY-P71517

Hygromycin-B kinase/HPH Protein, E.coli (His-SUMO)

hphHygromycin-B 4-O-kinase; EC 2.7.1.163; APH(4); Hygromycin B phosphotransferase; Hygromycin-B kinase
E.coli E. coli
HY-P700600

Hygromycin-B kinase/HPH Protein, E.coli (P. pastoris, His)

hphHygromycin-B 4-O-kinase; EC 2.7.1.163; APH(4); Hygromycin B phosphotransferase; Hygromycin-B kinase
E.coli P. pastoris
HY-P72853

BLK Protein, Human (sf9, GST)

Tyrosine-Protein kinase Blk; B lymphocyte kinase; p55-Blk; BLK
Human Sf9 insect cells

HY-P71549

STK11 Protein, Human (His-SUMO) hLKB1; Liver kinase B1; LKB1; PJS; Polarization related Protein LKB1; Renal carcinoma antigen NY-REN-19; Serine/Threonine kinase 11; Serine/threonine Protein kinase 11; Serine/threonine Protein kinase LKB1; Serine/threonine Protein kinase STK11; Serine/threonine-Protein kinase 11; Serine/threonine-Protein kinase LKB1; Serine/threonine-Protein kinase XEEK1; Stk11; STK11_HUMAN	Human	E. coli

HY-P70037

CDKN1B Protein, Human (His) rHuCyclin-dependent kinase inhibitor 1B/CDKN1B, His; Cyclin-Dependent kinase Inhibitor 1B; Cyclin-Dependent kinase Inhibitor p27; p27Kip1; CDKN1B; KIP1	Human	E. coli

HY-P71234

PRKG1 Protein, Human (HEK293, His)

cGMP-Dependent Protein kinase 1; cGK 1; cGK1; cGMP-Dependent Protein kinase I; cGKI; PRKG1; PRKG1B; PRKGR1A; PRKGR1B
Human HEK293

HY-P72048

BTK Protein, Human (Baculovirus, His) Agammaglobulinaemia tyrosine kinase; AGMX 1; AGMX1; AT; ATK; B cell progenitor kinase; B-cell progenitor kinase; BPK; Bruton agammaglobulinemia tyrosine kinase; Bruton tyrosine kinase; Bruton Tyrosine kinase; Btk; BTK_HUMAN; dominant-negative kinase-deficient Brutons tyrosine kinase; IMD 1; IMD1; MGC126261; MGC126262; OTTHUMP00000063593; PSCTK 1; PSCTK1; truncated Bruton agammaglobulinemia tyrosine kinase; Tyrosine Protein kinase BTK; Tyrosine-Protein kinase BTK; tyrosine-Protein kinase BTK isoform lacking exon 14; XLA	Human	Sf9 insect cells

HY-P700583

JAK1 Protein, Human (P. pastoris, His)

JAK1; JAK1A; JAK1B; Tyrosine-Protein kinase JAK1; Janus kinase 1; JAK-1
Human P. pastoris
HY-P700591

GSK-3 beta Protein, Human (P. pastoris, His)

Serine/threonine-Protein kinase GSK3B
Human P. pastoris

HY-P70381

EphB1 Protein, Human (HEK293, Fc) rHuEphrin type-B receptor 1/EphB1, Fc; Ephrin Type-B Receptor 1; ELK; EPH Tyrosine kinase 2; EPH-Like kinase 6; EK6; hEK6; Neuronally-Expressed EPH; Related Tyrosine kinase; NET; Tyrosine-Protein kinase Receptor EPH-2; EPHB1; ELK; EPHT2; HEK6	Human	HEK293

HY-P76326

FAM20B Protein, Human (HEK293, Fc)

Glycosaminoglycan xylosylkinase; Xylose kinase; KIAA0475
Human HEK293

HY-P70793

TrkB Protein, Human (HEK293, His) BDNF/NT-3 Growth Factors Receptor; GP145-TrkB; Trk-B; Neurotrophic Tyrosine kinase Receptor Type 2; TrkB Tyrosine kinase; Tropomyosin-Related kinase B; NTRK2; TRKB	Human	HEK293

HY-P70177

EphB1 Protein, Human (421a.a, HEK293, His) rHuEphrin Type-B Receptor 1/Ephb1, His; Ephrin Type-B Receptor 1; ELK; EPH Tyrosine kinase 2; EPH-Like kinase 6; EK6; hEK6; Neuronally-Expressed EPH; Related Tyrosine kinase; NET; Tyrosine-Protein kinase Receptor EPH-2; EPHB1; ELK; EPHT2; HEK6	Human	HEK293

HY-P77449

MOB4A/MOB1B Protein, Human (GST)

MOB kinase activator 1B; MOB4A; MOBKL1A; MOB1B
Human E. coli

HY-P700597

PIP4K2B Protein, Human (His) PIP4K2B; phosphatidylinositol-5-phosphate 4-kinase, type II, beta; phosphatidylinositol 4 phosphate 5 kinase, type II, beta , PIP5K2B; phosphatidylinositol-5-phosphate 4-kinase type-2 beta; PIP5KIIB; PIP5KIIbeta; PIP4KII-beta; PTDINS(4)P-5-kinase; PI(5)P 4-kinase type II beta; diphosphoinositide kinase 2-beta; ptdIns(5)P-4-kinase isoform 2-beta; 1-phosphatidylinositol-4-phosphate kinase; 1-phosphatidylinositol-5-phosphate 4-kinase 2-beta; phosphatidylinositol-4-phosphate 5-kinase, type II, beta; PI5P4KB; PIP5K2B	Human	E. coli

HY-P70917

MOB1A Protein, Human (His)

MOB kinase Activator 1A; Mob1 Alpha; Mob1A; Mob1 Homolog 1B; Mps One Binder kinase Activator-like 1B; MOB1A; C2orf6; MOB4B; MOBK1B; MOBKL1B
Human E. coli

HY-P71206

PIP4K2A Protein, Human (HEK293, His) 1-phosphatidylinositol 5-phosphate 4-kinase 2-alpha; Diphosphoinositide kinase 2-alpha; PIP5KIII; Phosphatidylinositol 5-phosphate 4-kinase type II alpha; PtdIns(4)P-5-kinase B isoform; PtdIns(4)P-5-kinase C isoform; PtdIns(5)P-4-kinase isoform 2-alpha	Human	HEK293

HY-P73090

GSK-3 beta Protein, Mouse (sf9, His)

Glycogen synthase kinase-3 beta; GSK-3 beta; Gsk3b
Mouse Sf9 insect cells
HY-P74114

GSK-3 beta Protein, Human (sf9, His)

Glycogen synthase kinase-3 beta; GSK-3 beta; Gsk3b
Human Sf9 insect cells
HY-P75973

PHKG1 Protein, Human (sf9, GST)

Phosphorylase b kinase gamma catalytic chain; PHK-gamma-M; PHKG1; PHKG
Human Sf9 insect cells
HY-P75751

EphB6 Protein, Human (HEK293)

Ephrin type-B receptor 6; HEP; Tyrosine-Protein kinase-defective receptor EPH-6; EPHB6
Human HEK293
HY-P73021

Ephrin B3 Protein, Rat (HEK293, Fc)

Ephrin-B3; EPH-related receptor tyrosine kinase ligand 8; LERK-8; EFNB3; EPLG8
Rat HEK293
HY-P73022

Ephrin B3 Protein, Rat (HEK293, His)

Ephrin-B3; EPH-related receptor tyrosine kinase ligand 8; LERK-8; EFNB3; EPLG8
Rat HEK293
HY-P75750

EphB3 Protein, Rat (HEK293, His)

Ephrin type-B receptor 3; mDK-5; Tyrosine-Protein kinase receptor SEK-4; Sek4
Rat HEK293
HY-P75752

EphB6 Protein, Human (HEK293, Fc)

Ephrin type-B receptor 6; HEP; Tyrosine-Protein kinase-defective receptor EPH-6; EPHB7
Human HEK293
HY-P75753

EphB6 Protein, Human (HEK293, His)

Ephrin type-B receptor 6; HEP; Tyrosine-Protein kinase-defective receptor EPH-6; EPHB8
Human HEK293
HY-P75754

EphB6 Protein, Mouse (HEK293, His)

Ephrin type-B receptor 6; HEP; Tyrosine-Protein kinase-defective receptor EPH-6; EPHB9
Mouse HEK293
HY-P77361

EphB6 Protein, Cynomolgus (HEK293, Fc)

Ephrin type-B receptor 6; HEP; Tyrosine-Protein kinase-defective receptor EPH-6; EPHB6
Cynomolgus HEK293
HY-P75228

Ephrin B3 Protein, Mouse (HEK293, His)

EFNB3; EPH-related receptor tyrosine kinase ligand 8; Ephrin B3; LERK-8; ELK-L3
Mouse HEK293
HY-P75229

Ephrin B3 Protein, Mouse (HEK293, hFc)

EFNB3; EPH-related receptor tyrosine kinase ligand 8; Ephrin B3; LERK-8; ELK-L3
Mouse HEK293
HY-P76264

CKMT1A Protein, Human (sf9, His)

Creatine kinase U-type, mitochondrial; Mia-CK; U-MtCK; CKMT; CKMT1B
Human Sf9 insect cells
HY-P76762

CaMKII beta/CAMK2B Protein, Human (sf9, His-GST)

Calcium/calmodulin-dependent Protein kinase type II subunit beta; CAM2; CAMK2; CAMKB
Human Sf9 insect cells
HY-P70402

Ephrin-B1/EFNB1 Protein, Human (HEK293, His)

rHuEphrin-B1/EFNB1, His; Ephrin-B1; EFL-3; ELK ligand; EPH-related receptor tyrosine kinase ligand 2; LERK-2
Human HEK293
HY-P75749

EphB3 Protein, Mouse (537a.a, HEK293, His)

Ephrin type-B receptor 3; mDK-5; Tyrosine-Protein kinase receptor SEK-4; Sek4
Mouse HEK293
HY-P72436

TrkB Protein, Mouse (398a.a, HEK293, His)

BDNF/NT-3 Growth Factors Receptor; GP145-TrkB; Trk-B; Neurotrophic Tyrosine kinase Receptor Type 2; TrkB Tyrosine kinase; NTRK2; TRKB
Mouse HEK293

HY-P70011A

Cyclophilin B/PPIB Protein, Human (HEK293, His) Ephrin-A1; EPH-Related Receptor Tyrosine kinase Ligand 1; LERK-1; Immediate Early Response Protein B61; Tumor Necrosis Factor Alpha-Induced Protein 4; TNF Alpha-Induced Protein 4; EFNA1; EPLG1; LERK1; TNFAIP4	Human	HEK293

HY-P70377

Ephrin-B2/EFNB2 Protein, Human (HEK293, His) rHuEphrin-B2/EFNB2, His; Ephrin-B2; EPH-Related Receptor Tyrosine kinase Ligand 5; LERK-5; HTK Ligand; HTK-L; EFNB2; EPLG5; HTKL; LERK5	Human	HEK293

HY-P70378

Ephrin-B2/EFNB2 Protein, Mouse (HEK293, Fc-His) rMuEphrin-B2/EFNB2, Fc-His; Ephrin-B2; ELF-2; EPH-related receptor tyrosine kinase ligand 5; HTK ligand; Elf2; Epl5; Eplg5; Htkl; Lerk5.	Mouse	HEK293

HY-P70374

Ephrin-B1/EFNB1 Protein, Mouse (HEK293, Fc-His) rMuEphrin-B1/EFNB1, Fc-His; Ephrin-B1; EFL-3; ELK ligand; ELK-L; EPH-related receptor tyrosine kinase ligand 2; LERK-2; EFNB1; EFL3; EPLG2; LERK2	Mouse	HEK293

HY-P70373

Ephrin-A1/EFNA1 Protein, Mouse (HEK293, Fc-His) rMuEphrin-A1/EFNA1, Fc-His; EPH-related receptor tyrosine kinase ligand 1; Immediate early response Protein B61; Epgl1; Epl1; Lerk1	Mouse	HEK293

HY-P70164

Ephrin-A1/EFNA1 Protein, Human (AAH32698.1, HEK293, His) rHuEphrin-A1, His; Ephrin-A1; EPH-Related Receptor Tyrosine kinase Ligand 1; LERK-1; Immediate Early Response Protein B61; Tumor Necrosis Factor Alpha-Induced Protein 4; TNF Alpha-Induced Protein 4; EFNA1; EPLG1; LERK1; TNFAIP4	Human	HEK293

HY-P72196

FGFR-3 Protein, Human (His-B2M) ACH; CD 333; CD333; CD333 antigen; CEK 2; CEK2; FGFR 3; FGFR-3; FGFR3; FGFR3_HUMAN; Fibroblast growth factor receptor 3 achondroplasia thanatophoric dwarfism; ; Fibroblast growth factor receptor 3; Heparin binding growth factor receptor; HSFGFR3EX; Hydroxyaryl Protein kinase; JTK 4; JTK4; MFR 3; SAM 3; Tyrosine kinase JTK 4; Tyrosine kinase JTK4; Z FGFR 3	Human	E. coli

Cat. No.	Product Name	Application	Reactivity

HY-P80788

Phospho-AKT1 (Ser473) Antibody AKT1; PKB; RAC; RAC-alpha serine/threonine-Protein kinase; Protein kinase B; PKB; Protein kinase B alpha; PKB alpha; Proto-oncogene c-Akt; RAC-PK-alpha	WB	Human, Mouse, Rat
Phospho-AKT1 (Ser473) Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 56 kDa, targeting to Phospho-AKT (Ser473). It can be used for WB assays with tag free, in the background of Human, Mouse, Rat.

HY-P80789

Phospho-AKT (Thr308) Antibody AKT1; PKB; RAC; RAC-alpha serine/threonine-Protein kinase; Protein kinase B; PKB; Protein kinase B alpha; PKB alpha; Proto-oncogene c-Akt; RAC-PK-alpha	ICC/IF, WB, IHC-F, IHC-P, ELISA	Human, Mouse, Rat
Phospho-AKT (Thr308) Antibody is a non-conjugated and Rabbit origined polyclonal antibody about 56 kDa, targeting to Phospho-AKT (Thr308). It can be used for ICC/IF,WB,IHC-F,IHC-P,ELISA assays with tag free, in the background of Human, Mouse, Rat.

HY-P80576

BTK Antibody (YA816) BTK; AGMX1; ATK; BPK; Tyrosine-Protein kinase BTK; Agammaglobulinaemia tyrosine kinase; ATK; B-cell progenitor kinase; BPK; Bruton tyrosine kinase	WB, IP	Human
BTK Antibody (YA816) is a non-conjugated and Mouse origined monoclonal antibody about 76 kDa, targeting to BTK (5B12). It can be used for WB,IP assays with tag free, in the background of Human.

HY-P80562

Aurora B Antibody AURKB; AIK2; AIM1; AIRK2; ARK2; STK1; STK12; STK5; Aurora kinase B; Aurora 1; Aurora- and IPL1-like midbody-associated Protein 1; AIM-1; Aurora/IPL1-related kinase 2; ARK-2; Aurora-related kinase 2; STK-1; Serine/threonine-Protein kinase 12	WB, IP	Human
Aurora B Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 39 kDa, targeting to Aurora B. It can be used for WB,IP assays with tag free, in the background of Human.

HY-P80819

Phospho-GSK3 (Tyr216/Tyr279) Antibody Serine/threonine-Protein kinase GSK3A; Serine/threonine-Protein kinase GSK3B	WB, IP	Mouse, Rat
Phospho-GSK3 (Tyr216/Tyr279) Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 51 kDa, targeting to Phospho-GSK3 (Tyr216/Tyr279). It can be used for WB,IP assays with tag free, in the background of Mouse, Rat.

HY-P80910

TBK1 Antibody (YA040) TBK1; NAK; Serine/threonine-Protein kinase TBK1; NF-kappa-B-activating kinase; T2K; TANK-binding kinase 1	WB	Human, Mouse, Rat, Hamster
TBK1 Antibody (YA040) is a non-conjugated and Rabbit origined monoclonal antibody about 84 kDa, targeting to TBK1. It can be used for WB assays with tag free, in the background of Human, Mouse, Rat, Hamster.

HY-P80698

GSK3 beta Antibody (YA744) GSK3B; Glycogen synthase kinase-3 beta; GSK-3 beta; Serine/threonine-Protein kinase GSK3B	WB, IHC-P, FC	Human, Mouse, Rat
GSK3 beta Antibody (YA744) is a non-conjugated and Mouse origined monoclonal antibody about 47 kDa, targeting to GSK3 beta. It can be used for WB,IHC-P,FC assays with tag free, in the background of Human, Mouse, Rat.

HY-P80820

Phospho-GSK3 beta (Ser9) Antibody GSK3B; Glycogen synthase kinase-3 beta; GSK-3 beta; Serine/threonine-Protein kinase GSK3B	WB, IHC-F, IHC-P, ICC/IF	Human, Mouse, Rat
Phospho-GSK3 beta (Ser9) Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 47 kDa, targeting to Phospho-GSK3 beta (Ser9). It can be used for WB,IHC-F,IHC-P,ICC/IF assays with tag free, in the background of Human, Mouse, Rat.

HY-P80850

Phospho-RSK2 (Ser227) Antibody RPS6KA3; ISPK1; MAPKAPK1B; RSK2; Ribosomal Protein S6 kinase alpha-3; S6K-alpha-3; 90 kDa ribosomal Protein S6 kinase 3; p90-RSK 3; p90RSK3; Insulin-stimulated Protein kinase 1; ISPK-1; MAP kinase-activated Protein kinase 1b; MAPK-activated	WB, IP	Human, Mouse, Rat
Phospho-RSK2 (Ser227) Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 84 kDa, targeting to Phospho-RSK2 (Ser227). It can be used for WB,IP assays with tag free, in the background of Human, Mouse, Rat.

HY-P80726

JAK1 Antibody (YA722) JAK1; JAK1A; JAK1B; Tyrosine-Protein kinase JAK1; Janus kinase 1; JAK-1	WB, ICC/IF, IP	Human, Rat
JAK1 Antibody (YA722) is a non-conjugated and Mouse origined monoclonal antibody about 133 kDa, targeting to JAK1 (8B8). It can be used for WB,ICC/IF,IP assays with tag free, in the background of Human, Rat.

HY-P80586

Casein Kinase 2 beta Antibody CSNK2B; CK2N; G5A; Casein kinase II subunit beta; CK II beta; Phosvitin; Protein G5a	WB, IHC-F, IHC-P, ICC/IF	Human, Mouse, Rat
Casein Kinase 2 beta Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 25 kDa, targeting to Casein Kinase 2 beta. It can be used for WB,IHC-F,IHC-P,ICC/IF assays with tag free, in the background of Human, Mouse, Rat.

HY-P80728

JNK Antibody AI849689; c Jun N terminal kinase 1; C-JUN kinase 1; c-Jun N-terminal kinase 1; EC 2.7.11.24; JAK 1A; JAK1A; JNK 1; JNK 46; JNK; JNK-46; JNK1A2; JNK21B1/2; MAP kinase 8; MAPK 8; MAPK8; Mitogen activated Protein kinase 8; Mitogen-activated Protein kinase 8	WB, IP	Human, Mouse, Rat, Hamster
JNK Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 48 kDa, targeting to JNK. It can be used for WB,IP assays with tag free, in the background of Human, Mouse, Rat, Hamster.

HY-P80729

JNK1 Antibody (YA720) AI849689; c Jun N terminal kinase 1; C-JUN kinase 1; c-Jun N-terminal kinase 1; EC 2.7.11.24; JAK 1A; JAK1A; JNK 1; JNK 46; JNK; JNK-46; JNK1A2; JNK21B1/2; MAP kinase 8; MAPK 8; MAPK8; Mitogen activated Protein kinase 8; Mitogen-activated Protein kinase 8	WB, ICC/IF	Human, Mouse, Rat
JNK1 (1A4) Antibody is a non-conjugated and Mouse origined monoclonal antibody about 48 kDa, targeting to JNK1 (1A4). It can be used for WB,ICC/IF assays with tag free, in the background of Human, Mouse, Rat.

HY-P80877

PYK2 Antibody (YA682) PTK2B; FAK2; PYK2; RAFTK; Protein-tyrosine kinase 2-beta; Calcium-dependent tyrosine kinase; CADTK; Calcium-regulated non-receptor proline-rich tyrosine kinase; Cell adhesion kinase beta; CAK-beta; CAKB; Focal adhesion kinase 2; FADK 2; Pro	WB, IHC-P	Human
PYK2 Antibody (YA682) is a non-conjugated and Mouse origined monoclonal antibody about 116 kDa, targeting to PYK2 (4B4). It can be used for WB,IHC-P assays with tag free, in the background of Human.

HY-P80831

Phospho-JNK1 (Thr183/Tyr185) Antibody AI849689; c Jun N terminal kinase 1; C-JUN kinase 1; c-Jun N-terminal kinase 1; EC 2.7.11.24; JAK 1A; JAK1A; JNK 1; JNK 46; JNK; JNK-46; JNK1A2; JNK21B1/2; MAP kinase 8; MAPK 8; MAPK8; Mitogen activated Protein kinase 8; Mitogen-activated Protein kinase 8	WB, IP	Human, Rat
Phospho-JNK1 (Thr183/Tyr185) Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 48 kDa, targeting to Phospho-JNK1 (Thr183/Tyr185). It can be used for WB,IP assays with tag free, in the background of Human, Rat.

HY-P80572

BRAF Antibody BRAF; BRAF1; RAFB1; Serine/threonine-Protein kinase B-raf; Proto-oncogene B-Raf; p94; v-Raf murine sarcoma viral oncogene homolog B1	WB	Human, Mouse, Rat
BRAF Antibody is a non-conjugated and Mouse origined monoclonal antibody about 84 kDa, targeting to BRAF (4E1). It can be used for WB assays with tag free, in the background of Human, Mouse.

HY-P80794

Phospho-BRAF (Thr401) Antibody BRAF; BRAF1; RAFB1; Serine/threonine-Protein kinase B-raf; Proto-oncogene B-Raf; p94; v-Raf murine sarcoma viral oncogene homolog B1	WB, IP	Human, Mouse, Rat
Phospho-BRAF (Thr401) Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 84 kDa, targeting to Phospho-BRAF (Thr401). It can be used for WB,IP assays with tag free, in the background of Human, Mouse, Rat.