1. Epigenetics
    Stem Cell/Wnt
    JAK/STAT Signaling
    Protein Tyrosine Kinase/RTK
  2. JAK
    FLT3
    Trk Receptor
  3. Lestaurtinib

Lestaurtinib (Synonyms: CEP-701; KT-5555)

Cat. No.: HY-50867 Purity: >99.0%
Handling Instructions

Lestaurtinib (CEP-701;KT-5555) is a multi-kinase inhibitor with potent activity against the Trk family of receptor tyrosine kinases. Lestaurtinib inhibits JAK2, FLT3 and TrkA with IC50s of 0.9, 3 and less than 25 nM, respectively.

For research use only. We do not sell to patients.

Lestaurtinib Chemical Structure

Lestaurtinib Chemical Structure

CAS No. : 111358-88-4

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 474 In-stock
Estimated Time of Arrival: December 31
1 mg USD 210 In-stock
Estimated Time of Arrival: December 31
5 mg USD 490 In-stock
Estimated Time of Arrival: December 31
10 mg   Get quote  
50 mg   Get quote  

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Description

Lestaurtinib (CEP-701;KT-5555) is a multi-kinase inhibitor with potent activity against the Trk family of receptor tyrosine kinases. Lestaurtinib inhibits JAK2, FLT3 and TrkA with IC50s of 0.9, 3 and less than 25 nM, respectively.

IC50 & Target[1]

JAK2

0.9 nM (IC50)

TrkA

25 nM (IC50)

FLT3

3 nM (IC50)

Storage
Powder -20°C 3 years
In solvent -80°C 6 months
  -20°C 1 month
References
Molecular Weight

439.46

Formula

C₂₆H₂₁N₃O₄

CAS No.

111358-88-4

SMILES

O=C(NC1)C2=C1C3=C(C4=C52)N(C6=C3C=CC=C6)[[email protected]@]([[email protected]@](O)(CO)C7)(C)O[[email protected]]7N4C8=C5C=CC=C8

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Room temperature in continental US; may vary elsewhere

Purity: >99.0%

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Lestaurtinib
Cat. No.:
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Lestaurtinib

Cat. No.: HY-50867