B-Raf IN 6
B-Raf IN 6 (compound 2c) is a potent inhibitor of protein kinase B-Raf with an IC50 of 1.7 nM. B-Raf IN 6 is devoid of binding to the secondary target PXR and resists rapid metabolism. B-Raf IN 6 has the potential for the research of cancer disease.
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- No. CAS: 2648698-34-2
- Fòrmula: C24H21F3N6O2S2
- Peso molecular:546.59
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| A-375 | IC50 |
5.12 nM
Compound: 2c
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Antiproliferative activity against human A-375 cells assessed as inhibition of cell growth measured after 5 days by MTT assay
Antiproliferative activity against human A-375 cells assessed as inhibition of cell growth measured after 5 days by MTT assay
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[PMID: 34958586] |
Chemical Information
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No. CAS 2648698-34-2
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Peso molecular 546.59
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Fòrmula C24H21F3N6O2S2
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SMILES
O=S(C1=CC(F)=CC=C1F)(NC2=CC=CC(C3=C(C4=NC(N)=NC=C4)SC(C5NCCCC5)=N3)=C2F)=O
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
B-Raf IN 6 Related Classifications
HY-142830 Related Classifications
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