2648698-34-2

B-Raf IN 6 Chemical Structure
2648698-34-2

Chemical Structure

B-Raf IN 6

  • CAS No.: 2648698-34-2
  • Formula:C24H21F3N6O2S2
  • Molecular Weight:546.59

IUPAC Name: N-(3-(5-(2-aminopyrimidin-4-yl)-2-(piperidin-2-yl)thiazol-4-yl)-2-fluorophenyl)-2,5-difluorobenzenesulfonamide

InChIKey: WMXXTMFNQQZVTB-UHFFFAOYSA-N

SMILES: O=S(C1=CC(F)=CC=C1F)(NC2=CC=CC(C3=C(C4=NC(N)=NC=C4)SC(C5NCCCC5)=N3)=C2F)=O

Biological Activity: B-Raf IN 6 (compound 2c) is a potent inhibitor of protein kinase B-Raf with an IC50 of 1.7 nM. B-Raf IN 6 is devoid of binding to the secondary target PXR and resists rapid metabolism. B-Raf IN 6 has the potential for the research of cancer disease[1].

Cat. No. Product Name Purity Description Pricing
HY-142830
B-Raf IN 6 B-Raf IN 6 (compound 2c) is a potent inhibitor of protein kinase B-Raf with an IC50 of 1.7 nM. B-Raf IN 6 is devoid of binding to the secondary target PXR and resists rapid metabolism. B-Raf IN 6 has the potential for the research of cancer disease.
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This product is a controlled substance and not for sale in your territory.

This product is not for sale in your territory.

This compound is listed in the SVHC (Substances of Very High Concern) candidate list of ECHA (European Chemicals Agency).

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References