2648698-34-2
Chemical Structure
B-Raf IN 6
- CAS No.: 2648698-34-2
- Formula:C24H21F3N6O2S2
- Molecular Weight:546.59
IUPAC Name: N-(3-(5-(2-aminopyrimidin-4-yl)-2-(piperidin-2-yl)thiazol-4-yl)-2-fluorophenyl)-2,5-difluorobenzenesulfonamide
InChIKey: WMXXTMFNQQZVTB-UHFFFAOYSA-N
SMILES: O=S(C1=CC(F)=CC=C1F)(NC2=CC=CC(C3=C(C4=NC(N)=NC=C4)SC(C5NCCCC5)=N3)=C2F)=O
Biological Activity: B-Raf IN 6 (compound 2c) is a potent inhibitor of protein kinase B-Raf with an IC50 of 1.7 nM. B-Raf IN 6 is devoid of binding to the secondary target PXR and resists rapid metabolism. B-Raf IN 6 has the potential for the research of cancer disease[1].
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B-Raf IN 6 | B-Raf IN 6 (compound 2c) is a potent inhibitor of protein kinase B-Raf with an IC50 of 1.7 nM. B-Raf IN 6 is devoid of binding to the secondary target PXR and resists rapid metabolism. B-Raf IN 6 has the potential for the research of cancer disease. | |||||||||||||||||||||
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Keywords
