TSSK2 Protein, Human (Active, sf9, GST)
The TSSK2 protein is a testis-specific serine/threonine protein kinase that is indispensable during late spermatogenesis and contributes to cytoplasmic remodeling. It is regulated by phosphorylating “Ser-288” of TSKS and SPAG16. TSSK2 Protein, Human (Active, sf9, GST) is the recombinant human-derived TSSK2 protein, expressed by sf9 insect cells , with N-GST labeled tag.
- Species: Human
- Source: Sf9 insect cells
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Storage:Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
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Biological Activity
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Technical Parameters
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Product Properties
- Documentation
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Biological Activity
Description
The TSSK2 protein is a testis-specific serine/threonine protein kinase that is indispensable during late spermatogenesis and contributes to cytoplasmic remodeling. It is regulated by phosphorylating “Ser-288” of TSKS and SPAG16. TSSK2 Protein, Human (Active, sf9, GST) is the recombinant human-derived TSSK2 protein, expressed by sf9 insect cells , with N-GST labeled tag.
Background
The TSSK2 protein, a testis-specific serine/threonine-protein kinase, plays an indispensable role in spermatid development, particularly in the late stages of spermatogenesis during cytoplasm reconstruction. It exerts its regulatory function by phosphorylating 'Ser-288' of TSKS and SPAG16. TSSK2's involvement is crucial for the intricate process of transforming a ring-shaped structure around the base of the flagellum, which originates from the chromatoid body. In the dynamic context of spermatogenesis, TSSK2 emerges as a key molecular player, orchestrating events that contribute to the structural and developmental changes necessary for the maturation of spermatids into fully functional sperm cells.
Technical Parameters
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Species Human
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Source Sf9 insect cells
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Tag N-GST
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Accession
Q96PF2 (M1-T358)
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Gene ID23617
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Molecular Construction
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N-term
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GST
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TSSK2 (M1-T358)
Accession # Q96PF2 -
C-term
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Protein Length
Full Length
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Synonyms
TSSK2; DGSG; SPOGA2; STK22B; Testis-specific serine/threonine-protein kinase 2; TSK-2; TSK2; TSSK-2; Testis-specific kinase 2; EC 2.7.11.1; DiGeorge syndrome protein G; DGS-G; Serine/threonine-protein kinase 22B; Serine/Threonine Kinase 22B (Spermiogenesi
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AA Sequence
MDDATVLRKKGYIVGINLGKGSYAKVKSAYSERLKFNVAVKIIDRKKTPTDFVERFLPREMDILATVNHGSIIKTYEIFETSDGRIYIIMELGVQGDLLEFIKCQGALHEDVARKMFRQLSSAVKYCHDLDIVHRDLKCENLLLDKDFNIKLSDFGFSKRCLRDSNGRIILSKTFCGSAAYAAPEVLQSIPYQPKVYDIWSLGVILYIMVCGSMPYDDSDIRKMLRIQKEHRVDFPRSKNLTCECKDLIYRMLQPDVSQRLHIDEILSHSWLQPPKPKATSSASFKREGEGKYRAECKLDTKTGLRPDHRPDHKLGAKTQHRLLVVPENENRMEDRLAETSRAKDHHISGAEVGKAST
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Molecular Weight
Approximately 66 kDa, based on SDS-PAGE under reducing conditions.
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Purity
≥ 80%, as determined by reducing SDS-PAGE.
Product Properties
Solution.
<1 EU/μg, determined by LAL method.
Please use rapid thawing with running water to thaw the protein.
Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
Shipping with dry ice.
Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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