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Results for "

cell+division

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Acetyl-CoA Carboxylase (1) ADC Antibody (2) ADC Payload (6) Akt (2) Aldehyde Dehydrogenase (ALDH) (2) AMPK (1) Androgen Receptor (1) Antibiotic (6) Antibody-Drug Conjugates (ADCs) (2) Antifolate (2) APC (1) Apoptosis (16) Aurora Kinase (3) Autophagy (4) Bacterial (21) Bcl-2 Family (1) Biochemical Assay Reagents (11) Caspase (1) CDK (8) ClpP (1) CMV (1) Cytochrome P450 (3) DAPK (2) DNA/RNA Synthesis (16) Drug Intermediate (1) EGFR (1) Endogenous Metabolite (15) Environmental Pollutants (7) ERK (1) Estrogen Receptor/ERR (1) FAK (1) Fluorescent Dye (2) Herbicide (15) HSV (2) Isotope-Labeled Compounds (10) JAK (1) JNK (1) Kinesin (3) Ligands for Target Protein for PROTAC (1) LIM Kinase (LIMK) (1) MDM-2/p53 (1) Microtubule/Tubulin (20) Mitosis (4) mTOR (1) Myosin (1) Na+/K+ ATPase (1) Necroptosis (3) Orthopoxvirus (3) p38 MAPK (1) Parasite (2) PARP (2) Penicillin-binding protein (PBP) (1) Phosphatase (3) Phytohormone (2) PI3K (2) Polo-like Kinase (PLK) (4) Potassium Channel (1) PROTACs (1) Ras (2) Reactive Oxygen Species (ROS) (1) Reference Standards (23) ROCK (1) SOD (2) Src (1) TNF Receptor (1) Topoisomerase (4) Transmembrane Glycoprotein (1) VRK (1)
By Research Areas:	Cancer (55) Cardiovascular Disease (1) Infection (22) Inflammation/Immunology (4) Metabolic Disease (8) Neurological Disease (6)
Click Chemistry:	Alkynes (1)
Oligonucleotides:	Guanosine (1) Nucleoside Analogs (1) Cholesterol (1)

130

Inhibitors & Agonists

Screening Libraries

Fluorescent Dyes

Biochemical Assay Reagents

Peptides

Inhibitory Antibodies

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Click Chemistry

Oligonucleotides

CFDA-SE 105+ Cited Publications CFSE; 5(6)-Carboxyfluorescein diacetate succinimidyl ester; 5(6)-CFDA N-succinmidyl ester	Fluorescent Dye	Others
CFDA-SE is a fluorescent dye that can penetrate the cell membrane. It can react with the free amine group in the cytoskeleton protein inside the cell, and finally form a protein complex with fluorescence. After entering the cell, CFDA-SE locates in the cell membrane, cytoplasm and nucleus, and the fluorescence staining is strongest in the nucleus . CFDA-SE dye can be uniformly inherited by the cells with cell division and proliferation, and its attenuation is proportional to the number of cell divisions. This phenomenon can be detected and analyzed by flow cytometry under the excitation light of 488 nm, and can be used to detect the proliferation of cells .

Aphidicolin 10+ Cited Publications	DNA/RNA Synthesis HSV Apoptosis Antibiotic Orthopoxvirus	Infection Inflammation/Immunology
Aphidicolin is an inhibitor of DNA polymerase α and δ, prevents mitotic cell division by interfering DNA polymerase activity. Aphidicolin is an antibiotic produced by mold Cephalosporium aphidicola, inhibits cellular deoxyribonucleic acid synthesis and the growth of herpes simplex virus. Aphidicolin exhibits anti-orthopoxvirus activity and potentiates apoptosis induced by arabinosyl nucleosides in a human promyelocytic leukemia cell line .

DM4 5 Publications Verification Ravtansine	Microtubule/Tubulin ADC Payload	Cancer
DM4 is is an antitubulin agent that inhibit cell division. DM4 can be used in the preparation of antibody agent conjugate.

Pyrimethamine 10+ Cited Publications Pirimecidan; Pirimetamin; RP 4753	Antifolate Parasite	Infection Cancer
Pyrimethamine (Pirimecidan) is a potent, orally active dihydrofolate reductase (DHFR) inhibitor. Pyrimethamine is an antimalarial agent. Pyrimethamine affects the nucleoprotein metabolism of malarial parasites by interference in the folic–folinic acid systems and affects cell division by inhibiting the conversion of dihydrofolate to tetrahydrofolate .

2'-Deoxyguanosine 5+ Cited Publications Deoxyguanosine; Guanine deoxyriboside	Endogenous Metabolite	Cancer
2’-Deoxyguanosine (Deoxyguanosine) is a purine nucleoside with a variety of biological activities. 2’-Deoxyguanosine can induce DNA division in mouse thymus cells. 2’-Deoxyguanosine is a potent cell division inhibitor in plant cells .

Kinetin 5+ Cited Publications 6-Furfuryladenine; N6-Furfuryladenine	Environmental Pollutants SOD	Neurological Disease
Kinetin (N6-furfuryladenine) belongs to the family of N6-substituted adenine derivatives known as cytokinins, which are plant hormones involved in cell division, differentiation and other physiological processes. Kinetin has anti-aging effects .

Auristatin F	ADC Payload Microtubule/Tubulin	Cancer
Auristatin F is a potent cytotoxin in antibo-conjugated agents and an analogue of MMAF. Auristatin F is a potent microtubule inhibitor and vascular damaging agent (VDA). Auristatin F inhibits cell division by preventing tubulin aggregation.Auristatin F can be used in antibody-drug conjugates (ADC) .

Cholesteryl hemisuccinate	Topoisomerase DNA/RNA Synthesis Apoptosis Necroptosis	Cancer
Cholesteryl hemisuccinate is a with hepatoprotective an anticancer activity. Cholesteryl hemisuccinate inhibits Acetaminophen (AAP, HY-66005) hepatotoxicity, and prevents AAP-induced hepatic apoptosis and necrosis. Cholesteryl hemisuccinate inhibits DNA polymerase and DNA topoisomerase to inhibit DNA replication and repair and cell division. Thus, Cholesteryl hemisuccinate inhibits tumor growth .

Auristatin E	Microtubule/Tubulin ADC Payload	Cancer
Auristatin E is a cytotoxic microtubule polymerization inhibitor with potent and selective antitumor activity. Auristatin E is a cytotoxin in antibody-drug conjugates (ADC). Auristatin E inhibits cell division by blocking the polymerisation of tubulin, promising for research in B-cell malignancies. Auristatin E, a synthetic analogue of the Dolastatin 10 (HY-15580), is linear peptides comprised of four amino acids .

Coumermycin A1 Maximum Cited Publications 27 Publications Verification	JAK Bacterial Orthopoxvirus	Metabolic Disease
Coumermycin A1 is a JAK2 signal activator. Coumermycin A1 inhibits DNA Gyrase which thereby inhibits cell division in bacteria. Coumermycin A1 shows anti-orthopoxvirus activity.

Simurosertib 10+ Cited Publications TAK-931	CDK	Cancer
Simurosertib (TAK-931) is an orally active, selective and ATP-competitive cell division cycle 7 (CDC7) kinase inhibitor, with an IC₅₀ of <0.3 nM. Simurosertib has anti-cancer activity .

Cholesterol hemisuccinate Tris salt Cholesterol hydrogen succinate Tris salt; CHS-Tris	Biochemical Assay Reagents Topoisomerase DNA/RNA Synthesis Apoptosis Necroptosis	Inflammation/Immunology Cancer
Cholesterol hemisuccinate (Cholesterol hydrogen succinate) Tris salt is a compound with hepatoprotective and anticancer activity. Cholesterol hemisuccinate Tris salt inhibits Acetaminophen (AAP) (HY-66005) hepatotoxicity, and prevents AAP-induced hepatic apoptosis and necrosis. Cholesterol hemisuccinate Tris salt inhibits DNA polymerase and DNA topoisomerase to inhibit DNA replication and repair and cell division. Cholesterol hemisuccinate Tris salt inhibits tumor growth. Cholesterol hemisuccinate Tris salt can be used for buffer preparation .

6-Benzylaminopurine 4 Publications Verification Benzyladenine; 6-BAP; N6-Benzyladenine	Environmental Pollutants Endogenous Metabolite	Others
6-Benzylaminopurine (Benzyladenine) is a cytokinin that causes plant growth and development by stimulating cell division and inhibiting respiratory kinases, thereby prolonging the preservation of green vegetables .

VRK-IN-1 5 Publications Verification	VRK	Neurological Disease
VRK-IN-1 is a potent and selective inhibitor of vaccinia-related kinases 1 (VRK1), with an IC₅₀ of 150 nM. VRK1 is human Ser/Thr protein kinases associated with increased cell division and neurological disorders .

PC190723	Bacterial	Infection
PC190723 is a bacterial cell division protein FtsZ inhibitor (IC₅₀ = 55 nM). PC 190723 prevents cell division. PC190723 has potent and selective bactericidal activity against staphylococci, including methicillin- and multi-drug-resistant Staphylococcus aureus. PC190723 induces nucleated assembly of Bs-FtsZ into single-stranded coiled protofilaments and polymorphic condensates. PC190723 can be studied in anti-bacterial infection research .

ARQ 621	Kinesin	Cancer
ARQ 621 is an allosteric, potent and selective inhibitor of Eg5, a microtubule-based ATPase motor protein involved in cell division. Anti-tumor activity . ARQ 621 is a kinesin inhibitor . ARQ 621 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Silver nitrite	Biochemical Assay Reagents Bacterial	Infection
Silver nitrite is an inorganic compound with the chemical formula AgNO₂. Silver nitrite can inhibit cell division and bacterial growth by interfering with protein synthesis .

Spastazoline 4 Publications Verification	Microtubule/Tubulin	Others
Spastazoline is a selective spastin (a microtubule-severing AAA protein) inhibitor, with an IC₅₀ of 99 nM for Human spastin. Spastazoline can be used for cell division- and intracellular vesicle transport-related research .

ML-099 5 Publications Verification CID-888706	Ras	Cancer
ML-099 (CID-888706) is a pan Ras-related GTPases activator that can activate Rac1, cell division cycle 42, Ras, Rab7, and Rab-2A .

Napropamide Napropamid	Environmental Pollutants DNA/RNA Synthesis Herbicide	Others
Napropamide (Napropamid) is an amide herbicide that can be used to control weeds in fruits, vegetables, tobacco, and ornamental plants. Napropamide mainly exerts its effect by inhibiting DNA synthesis and cell division. Napropamide has moderate to high persistence in the field, with a half-life of 24-131 days, and is prone to photodegradation .

MreB Perturbing Compound A22 hydrochloride A22 hydrochloride	Bacterial	Infection
MreB Perturbing Compound A22 hydrochloride (A22 hydrochloride) is a reversible MreB inhibitor and antimicrobial agent that exhibits bacteriostatic activity against Escherichia coli, with low activity against Gram-positive bacteria. MreB Perturbing Compound A22 hydrochloride rapidly and reversally delocalizes MreB from the helical/circular structures in cells, impairs MreB function, and reduces the binding of MreB to the chromosomal region proximal to the replication origin. MreB Perturbing Compound A22 hydrochloride alters the cell morphology of caulobacters to round/lemon-shaped, slows caulobacter growth, blocks their cell division, and induces the formation of spherical morphology, asymmetric division, and anucleate cells in Escherichia coli. MreB Perturbing Compound A22 hydrochloride is used for studies related to bacterial rod-shaped morphology determination, chromosome segregation, and cell division mechanisms .

3MB-PP1	Polo-like Kinase (PLK) CDK DAPK	Others
3MB-PP1, a bulky purine analog, is a Polo-like kinase 1 (Plk1) inhibitor. 3MB-PP1 blocks mitotic progression and cell division arise through target Plk1 in in cells expressing analog-sensitive Plk1 alleles. 3MB-PP1 specifically inhibits the activity of analog-sensitive Ssn3 (Cdk8). 3MB-PP1 inhibits Leu93 Mutant Zipper-interacting protein kinase (Leu93-ZIPK; IC₅₀=2 μM). 3MB-PP1 can be used for the research of hypha formation of Candida albicans and cell division .

3-Methoxybenzamide 1 Publications Verification 3-MBA	PARP Bacterial	Cancer
3-Methoxybenzamide (3-MBA), an inhibitor of ADP-ribosyltransferase (ADPRTs) and PARP, inhibits cell division in Bacillus subtilis, leading to filamentation and eventually lysis of cells . 3-Methoxybenzamide (3-MBA) enhances in vitro plant growth, microtuberization, and transformation efficiency of blue potato (Solanum tuberosum L. subsp. andigenum) .

Ochratoxin B	Endogenous Metabolite	Metabolic Disease
Ochratoxin B is an orally active secondary metabolite of Aspergillus ochraceus and non-chlorinated analog of the mycotoxin Ochratoxin A. Ochratoxin B reduces the toxic effects of Ochratoxin A (HY-N6788). Ochratoxin B inhibits cell division. Ochratoxin B causes craniofacial malformations in Xenopus laevis embryos .

Metazachlor BAS 479H	Herbicide Cytochrome P450 DNA/RNA Synthesis	Others
Metazachlor (BAS 479H) is a herbicide belonging to the chloroacetamides class. Metazachlor can inhibit the synthesis of very long chain fatty acids during the germination and emergence of weed seeds, thereby interfering with cell division and tissue differentiation, and thus hindering the normal growth and development of weeds .

Avanbulin BAL27862	Microtubule/Tubulin	Cancer
Avanbulin (BAL27862) is a potent, Colchicine site-binding, tubulin assembly inhibitor. Avanbulin inhibits tubulin assembly at 37 °C with an IC₅₀ of 1.4 μM. Avanbulin binds to tubulin with an apparent K_d value of 244 nM. Avanbulin can be used for the research of cancer and cell division .

ATIC-IN-1 acetate 1 Publications Verification	Endogenous Metabolite	Cancer
ATIC-IN-1 (compound 14) acetate is an inhibitor targeting to Aminoimidazole carboxamide ribonucleotide transformylase/inosine monophosphate cyclohydrolase (ATIC) dimerization with a K_i value of 685 nM, whcich catalyzes de novo purine biosynthesis. ATIC dimerization is crucial for its aminoimidazole carboxamide ribonucleotide (AICAR) transformylase activity. ATIC-IN-1 acetate exhibits anti-tumor activity via reduction in cell numbers and cell division rates .

Dihydroconiferyl alcohol	Endogenous Metabolite	Others
Dihydroconiferyl alcohol is a cell division factor. Dihydroconiferyl alcohol can be isolated from the American sycamore (Acer pseudoplatanus L.). Dihydroconiferyl alcohol inhibits the degradation of Indole-3-acetic acid (HY-18569). Dihydroconiferyl alcohol can stimulate the growth of soybean and tobacco callus tissue and synergistically enhance Indole-3-acetic acid-induced hypocotyl elongation in cucumber. Dihydroconiferyl alcohol can be used in the research of plant growth regulation .

*6-Benzylaminopurine, suitable for plant cell* culture** Benzyladenine, suitable for plant cell culture; 6-BAP, suitable for plant cell culture; N6-Benzyladenine, suitable for plant cell culture	Biochemical Assay Reagents	Others
6-Benzylaminopurine,suitable for plant cell culture is a cytokinin that induces plant growth and development by stimulating cell division, and prolongs the freshness of green vegetables through inhibiting respiratory kinases .

CFDA-SE (solution)	Fluorescent Dye	Others
CFDA-SE (solution) is a fluorescent dye that can penetrate the cell membrane. It can react with the free amine group in the cytoskeleton protein inside the cell, and finally form a protein complex with fluorescence. After entering the cell, CFDA-SE locates in the cell membrane, cytoplasm and nucleus, and the fluorescence staining is strongest in the nucleus . CFDA-SE dye can be uniformly inherited by the cells with cell division and proliferation, and its attenuation is proportional to the number of cell divisions. This phenomenon can be detected and analyzed by flow cytometry under the excitation light of 488 nm, and can be used to detect the proliferation of cells . Solvent and concentration: DMSO: 5 mM

(R)-Simurosertib (R)-TAK-931	CDK	Others
(R)-Simurosertib ((R)-TAK-931) is the (R)-enantiomer of Simurosertib. Simurosertib (TAK-931) is an orally active, selective and ATP-competitive cell division cycle 7 (CDC7) kinase inhibitor, with an IC₅₀ of <0.3 nM .

AM-5308	Kinesin Microtubule/Tubulin	Cancer
AM-5308 is the inhibitor for KIF18A (IC₅₀=47 nM) that inhibits KIF18A-mediated microtubule ATPase activity. AM-5308 activates mitotic checkpoints, regulates cell division processes, including chromosome segregation and spindle assembly. AM-5308 exhibits antitumor activity .

CDC25B-IN-1 1 Publications Verification	Phosphatase	Cancer
CDC25B-IN-1 (compound 4a) is a potent inhibitor of cell division cycle 25B (CDC25B) phosphatase, with a K_i of 8.5 μM. CDC25B-IN-1 potently inhibits cell proliferation and colony formation, causes an increase of the G2/M phase .

Lifastuzumab vedotin RG-7599; DNIB-0600A; NaPi2b-ADC	Antibody-Drug Conjugates (ADCs)	Cancer
Lifastuzumab vedotin (RG-7599; DNIB0600A) is an antibody-drug conjugate (ADC) that comprises a humanized IgG1 anti-NaPi2b monoclonal antibody (MNIB2126A) and a potent antimitotic agent, monomethyl auristatin E (MMAE), which inhibits cell division by blocking the polymerization of tubulin. Lifastuzumab vedotin has the potential for non-small cell lung cancer (NSCLC) and platinum-resistant ovarian cancer (PROC) research .

2-O-(α-D-Glucopyranosyl)glycerol (55% in water) Glucosylglycerol	Biochemical Assay Reagents	Others
2-O-(α-D-Glucopyranosyl) glycerol (55% in water) (Glucosylglycerol) is a glycerol glycoside and compatible solute. 2-O-(α-D-Glucopyranosyl) glycerol is isolable from the marine cyanobacterium Oscillatoria sp. 2-O-(α-D-Glucopyranosyl) glycerol (55% in water) acts as a salt stress protectant in Synechocystis sp. PCC 6803 ΔggpS cells. It enhances salt tolerance of Synechocystis sp. PCC 6803 ΔggpS cells and maintains cell division under salt stress .

Chlorpropham 1 Publications Verification	Environmental Pollutants Herbicide	Others
Chlorpropham is a carbamate herbicide and plant growth regulator. Chlorpropham inhibits mitosis and cell division by interfering with the organisation of the spindle microtubules .

ML-097 2 Publications Verification CID-2160985	Ras	Cancer
ML-097 (CID-2160985) is a pan Ras-related GTPases activator that can activate Rac1, cell division cycle 42, Ras, and Rab7 .

DL-Glutamic acid	Endogenous Metabolite DNA/RNA Synthesis Bacterial	Infection
DL-Glutamic acid is a racemic amino acid mixture and an antibacterial agent. DL-Glutamic acid reduces RNA and DNA levels, with a more significant effect on RNA. DL-Glutamic acid inhibits cell division of Rhodospirillum rubrum .

DM4-d6	Isotope-Labeled Compounds Microtubule/Tubulin ADC Payload	Cancer
DM4-d₆ is deuterium labeled DM4. DM4 is is an antitubulin agent that inhibit cell division. DM4 can be used in the preparation of antibody agent conjugate.

Chlorthal-dimethyl 1 Publications Verification Dimethyl tetrachloroterephthalate	Environmental Pollutants Biochemical Assay Reagents	Others
Chlorthal-dimethyl (Dimethyl tetrachloroterephthalate) is a plant growth regulator. Chlorthal-dimethyl affects cell division and differentiation, interfering with the normal development of vascular tissue. Chlorthal-dimethyl causes localized swelling of tomato hypocotyls and disrupts normal mitosis in germinating millet seedlings .

4-Chlorophenoxyacetic acid (4-CPA) 4-CPA; p-Chlorophenoxyacetic acid	Environmental Pollutants Biochemical Assay Reagents Herbicide	Others
4-Chlorophenoxyacetic acid (4-CPA) is a widely used herbicide and plant growth regulator. 4-Chlorophenoxyacetic acid (4-CPA) mimics endogenous auxin and regulates plant cell division, differentiation and gene expression. 4-Chlorophenoxyacetic acid (4-CPA) is used to control weeds and promote fruit growth .

Cholesteryl hemisuccinate (Standard)	Reference Standards Topoisomerase DNA/RNA Synthesis Apoptosis Necroptosis	Cancer
Cholesteryl hemisuccinate (Standard) is the analytical standard of Cholesteryl hemisuccinate. This product is intended for research and analytical applications. Cholesteryl hemisuccinate is a with hepatoprotective an anticancer activity. Cholesteryl hemisuccinate inhibits Acetaminophen (AAP, HY-66005) hepatotoxicity, and prevents AAP-induced hepatic apoptosis and necrosis. Cholesteryl hemisuccinate inhibits DNA polymerase and DNA topoisomerase to inhibit DNA replication and repair and cell division. Thus, Cholesteryl hemisuccinate inhibits tumor growth[1][2].

Auristatin E-d8	Isotope-Labeled Compounds Microtubule/Tubulin ADC Payload	Cancer
Auristatin E-d₈ is the deuterium labeled Auristatin E (HY-15582). Auristatin E is a cytotoxic microtubule polymerization inhibitor with potent and selective antitumor activity. Auristatin E is a cytotoxin in antibody-drug conjugates (ADC). Auristatin E inhibits cell division by blocking the polymerisation of tubulin, promising for research in B-cell malignancies. Auristatin E, a synthetic analogue of the Dolastatin 10 (HY-15580), is linear peptides comprised of four amino acids .

Pendimethalin (Standard)	Herbicide Reference Standards	Others
Pendimethalin (Standard) is the analytical standard of Pendimethalin. This product is intended for research and analytical applications. Pendimethalin is an herbicide that controls annual grasses and certain broadleaf weeds. Pendimethalin inhibits cell division and cell elongation .

Sobuzoxane MST 16	Topoisomerase	Neurological Disease Cancer
Sobuzoxane (MST-16) is an orally active topoisomerase II inhibitor. Sobuzoxane causes irreversible inhibition of cell division. Sobuzoxane can be used in the study of non-Hodgkin's lymphoma that is resistant to conventional chemotherapy or has recurred .

4-Chlorophenoxyacetic acid sodium 4-CPA sodium; p-Chlorophenoxyacetic acid sodium	Biochemical Assay Reagents Herbicide	Others
4-Chlorophenoxyacetic acid sodium is a widely used herbicide and plant growth regulator. 4-Chlorophenoxyacetic acid sodium mimics endogenous auxin and regulates plant cell division, differentiation and gene expression. 4-Chlorophenoxyacetic acid sodium is used to control weeds and promote fruit growth .

Cat. No.	Product Name

HY-L196

Protein Kinase Compound Library

4,332 compounds

Protein Kinases (PTKs) are a class of phosphotransferases that phosphorylate proteins. Protein kinases participate in many signal transduction pathways including those involved with growth, differentiation, and cell division. Protein kinase not only plays an important role in the process of cell activation, but also its abnormal expression is closely related to the pathogenesis of many diseases. So far, the protein kinase family has become one of the most important drug targets. The most common drug targets include ALK, B-Raf, BCR-Abl, EGFR, and VEGFR.

MCE designs a unique collection of 4,332 bioactive compounds targeting protein kinases, which is an important tool for the development of drug targeting protein kinases.

HY-L230

FDA Kinase Inhibitor Library

329 compounds

Kinases are enzymes that catalyze the addition of phosphate groups to substrate molecules, a process known as phosphorylation. Protein phosphorylation serves as a critical regulatory mechanism for numerous cellular processes, including cell division, metabolism, and signal transduction. The human genome encodes over 500 kinases, which collectively regulate approximately 50% of cellular functions. Due to their pivotal roles, kinases represent one of the most important target classes in drug development.

Kinase inhibitors can selectively block the activity of disease-associated kinases, making them valuable therapeutics for conditions such as cancer and inflammatory diseases. FDA-approved kinase inhibitors have undergone extensive preclinical and clinical studies, demonstrating high bioactivity, favorable safety profiles, and good bioavailability, rendering them suitable for investigating new therapeutic indications.

HY-L201

Cell Proliferation Compound Library

3,398 compounds

Cell proliferation, the increase in cell numbers resulting from cell division, is a complex and tightly regulated process. Cell proliferation is regulated by coordinated entry into the cell cycle, and changes in proliferation are closely linked to disease development. Evolutionary dynamics links tumor growth and progression with cell proliferation, cell death, and mutation rates. In addition, cell proliferation is central to degenerative diseases, the development of which is often accompanied by accelerated multiplication of cancer cells. Therefore, assays of cell proliferation levels are frequently used for laboratory research purposes and increasingly for clinical assessment of tumor aggressiveness and potentially to guide care. It has been shown that multiple key targets are collectively involved in regulating the process of cell proliferation, such as CDK, E2F, pRB, β-Catenin, and others.

MCE collects 3,398 compounds that target and regulate key targets of cell proliferation, which can be used in studies of cell proliferation mechanisms and drug discovery.

HY-L009M

Kinase Inhibitor Library Mini

270 compounds

Kinases is a class of enzymes that adds chemicals called phosphates to other molecules, such as sugars or proteins. Protein phosphorylation serves as a critical regulatory mechanism for numerous cellular processes including cell division, metabolism, and signal transduction, with approximately 50% of cellular functions in humans being regulated by kinase activity. In drug discovery, kinases represent a major category of therapeutic targets, and kinase inhibitors constitute an important class of pharmaceuticals that block the activity of specific disease-associated enzymes, particularly in cancer and inflammatory disorders. Small molecule kinase inhibitors represent one of the fastest-growing drug categories, having received U.S. Food and Drug Administration (FDA) approval for both oncological and non-oncological indications. As of September 2023, over 70 FDA-approved small molecule kinase inhibitors are commercially available.

The MCE Kinase Inhibitor Library Mini contains 270 kinase inhibitors primarily targeting protein kinases (VEGFR, EGFR, BTK, CDK, Akt, etc.), lipid kinases (PI3K, PI4K, SK, etc.), and carbohydrate kinases. This collection includes 1-3 highly specific representative compounds per target, optimized for screening of kinase-related drug targets in pharmaceutical research.

HY-L938

Antifungal Lead-like compound library

8350 compounds

Currently,the incidence and mortality rates of clinical fungal infections remain high. Existing antifungal drugs are limited in variety and associated with numerous adverse effects, creating an urgent demand for the development of novel antifungal agents. Antifungal compound libraries can support the screening and development of new antifungal drugs.

The mechanisms of action of antifungal drugs cover key processes such as fungal cell membrane synthesis, cell wall synthesis, and cell division. They exert fungicidal or fungistatic effects by specifically targeting different molecular pathways. This library includes a variety of core analogs of antifungal drugs, making it adaptable to antifungal research in diverse scenarios. It can be used for the high-throughput screening of novel antifungal drug candidates, enabling the rapid identification of compounds with potential antifungal activity and facilitating the elucidation of drug-target interactions and resistance mechanisms. Additionally, it supports the screening of compounds and combinations that reverse drug resistance, thereby uncovering the novel antifungal potential of existing compounds.

The library comprises 8350 compounds with a well-defined screening strategy. The core sources of the compounds include analogs of known antifungal active moleculeswith a similarity score of ≥ 0.6 MCE has collected more than 500 antifungal molecules.All screened compounds conform to lead-like physicochemical properties, exhibiting both structural diversity and drug-like characteristics, and providing valuable support for the research and development of novel antifungal drugs.

Cat. No.	Product Name	Type

HY-D0938

CFDA-SE

105+ Cited Publications

CFSE; 5(6)-Carboxyfluorescein diacetate succinimidyl ester; 5(6)-CFDA N-succinmidyl ester

Fluorescent Dyes

CFDA-SE is a fluorescent dye that can penetrate the cell membrane. It can react with the free amine group in the cytoskeleton protein inside the cell, and finally form a protein complex with fluorescence. After entering the cell, CFDA-SE locates in the cell membrane, cytoplasm and nucleus, and the fluorescence staining is strongest in the nucleus . CFDA-SE dye can be uniformly inherited by the cells with cell division and proliferation, and its attenuation is proportional to the number of cell divisions. This phenomenon can be detected and analyzed by flow cytometry under the excitation light of 488 nm, and can be used to detect the proliferation of cells .

HY-DY1009

CFDA-SE (solution)

Fluorescent Dyes

CFDA-SE (solution) is a fluorescent dye that can penetrate the cell membrane. It can react with the free amine group in the cytoskeleton protein inside the cell, and finally form a protein complex with fluorescence. After entering the cell, CFDA-SE locates in the cell membrane, cytoplasm and nucleus, and the fluorescence staining is strongest in the nucleus . CFDA-SE dye can be uniformly inherited by the cells with cell division and proliferation, and its attenuation is proportional to the number of cell divisions. This phenomenon can be detected and analyzed by flow cytometry under the excitation light of 488 nm, and can be used to detect the proliferation of cells .
Solvent and concentration: DMSO: 5 mM

Cat. No.	Product Name	Type

HY-W034067

Silver nitrite	Biochemical Assay Reagents
Silver nitrite is an inorganic compound with the chemical formula AgNO₂. Silver nitrite can inhibit cell division and bacterial growth by interfering with protein synthesis .

HY-165099

C-8 Ceramide-1-phosphate

Biochemical Assay Reagents

C-8 Ceramide-1-phosphate is a cell apoptosis inhibitor and a cell survival inducer that can stimulate DNA synthesis and cell division. C-8 Ceramide-1-phosphate can inhibit acidic sphingomyelinase (SMase) and stimulate PI3-K, which in turn produces PIP3; PIP3 can also inhibit acidic SMase. The C-8 Ceramide-1-phosphate and ceramide can be interconverted in cells through kinase and phosphatase activity, and maintaining the balance between the two is crucial for cellular and tissue homeostasis .

HY-B0941A

*6-Benzylaminopurine, suitable for plant cell* culture** Benzyladenine, suitable for plant cell culture; 6-BAP, suitable for plant cell culture; N6-Benzyladenine, suitable for plant cell culture	Biochemical Assay Reagents
6-Benzylaminopurine,suitable for plant cell culture is a cytokinin that induces plant growth and development by stimulating cell division, and prolongs the freshness of green vegetables through inhibiting respiratory kinases .

HY-19698

4-Chlorophenoxyacetic acid (4-CPA) 4-CPA; p-Chlorophenoxyacetic acid	Biochemical Assay Reagents
4-Chlorophenoxyacetic acid (4-CPA) is a widely used herbicide and plant growth regulator. 4-Chlorophenoxyacetic acid (4-CPA) mimics endogenous auxin and regulates plant cell division, differentiation and gene expression. 4-Chlorophenoxyacetic acid (4-CPA) is used to control weeds and promote fruit growth .

HY-19698A

4-Chlorophenoxyacetic acid sodium 4-CPA sodium; p-Chlorophenoxyacetic acid sodium	Biochemical Assay Reagents
4-Chlorophenoxyacetic acid sodium is a widely used herbicide and plant growth regulator. 4-Chlorophenoxyacetic acid sodium mimics endogenous auxin and regulates plant cell division, differentiation and gene expression. 4-Chlorophenoxyacetic acid sodium is used to control weeds and promote fruit growth .

HY-19700B

trans-Zeatin Sterile Solution (1 mg/ml)	Biochemical Assay Reagents
trans-Zeatin Sterile Solution (1 mg/mL) is a ready-to-use cytokinin solution and a core regulatory agent for promoting cell division and shoot regeneration in plant tissue culture.

HY-18570C

1-Naphthaleneacetic acid Sterile Solution (1 mg/ml) 1-NAA Sterile Solution (1 mg/ml)	Biochemical Assay Reagents
1-Naphthaleneacetic acid Sterile Solution (1 mg/mL) is a ready-to-use synthetic plant growth regulator (Auxin) stock solution, a core reagent for regulating cell division, differentiation and growth in plant tissue culture.

HY-Y0070

Cyanamide

Biochemical Assay Reagents

Cyanamide is a cell division and plant growth inhibitor, as well as an allelochemical derived from Vicia villosa. Cyanamide inhibits root growth and biomass accumulation in a dose-dependent manner by disrupting the formation of mitotic spindles and phragmoplast complexes, reducing the number of mitotic cells and blocking the cell cycle. The effects of Cyanamide are partially reversible after removal from low-concentration environments. Cyanamide is also a specific inhibitor of aldehyde dehydrogenase (ALDH). Although Cyanamide has no direct effect on tumor growth, it can significantly enhance the anti-tumor efficacy of Cyclophosphamide (HY-17420) at non-toxic doses by inhibiting the inactivation of Cyclophosphamide. Cyanamide enables Cyclophosphamide to exert equivalent therapeutic effects at lower doses, effectively inhibiting the growth of primary and metastatic tumors and prolonging the lifespan of tumor-bearing mice. Cyanamide is commonly used in studies related to ha-1 hepatoma and rls lymphosarcoma .

Cat. No.	Product Name	Target	Research Area

HY-P5712

Gramicidin S 1 Publications Verification Gramicidin soviet	Antibiotic Bacterial Na+/K+ ATPase	Infection
Gramicidin S (Gramicidin soviet) is a cationic cyclic peptide antibiotic that selectively targets bacterial cell membranes and has anticancer activity. Gramicidin S also exerts antibacterial activity by destroying membrane integrity and interfering with membrane protein function. Gramicidin S inserts into the phospholipid bilayer through hydrophobic amino acid residues, specifically binds to negatively charged membrane lipids and disrupts membrane structure, thereby inhibiting cell division and cell wall synthesis, and ultimately causing bacterial death. Gramicidin S also inhibits ion channels, with IC₅₀s of 41 μM, 24 μM, and 3 μM for Na ⁺/K ⁺-ATPase, tobacco leaf plasma membrane Mg ²⁺/K ⁺-ATPase, and rat heart plasma membrane Ca ²⁺-ATPase, respectively .

HY-W037817

Dimethyl L-glutamate Dimethyl glutamate	Potassium Channel Bacterial	Infection Metabolic Disease
Dimethyl L-glutamate (Dimethyl glutamate), a membrane-permeable analog of Glutamate, can stimulate insulin release induced by Glucose. Dimethyl L-glutamate suppresses the K_ATP channel activities. Dimethyl L-glutamate inhibits E. gracilis growth and causes abnormal cell division. Dimethyl L-glutamate can be used in the research of diabetes, glucose transport, phosphorylation, and further metabolism .

HY-P10785

Iturin A-2	Bacterial Antibiotic	Infection
Iturin A-2 is a cyclic lipopeptide discovered in B. subtilis and exhibits inhibitory activity against the plant pathogenic fungus P. expansum (MIC = 8 µg/disk). Iturin A-2 is cytotoxic to MCF-7 and BT474 breast cancer cells, as well as HeLa cervical cancer cells, with IC₅₀ values of 66.81, 95.04, and 77.5 µg/mL, respectively. In greenhouse studies, Iturin A-2 at concentrations of 100 and 300 mg/kg Iturin A-2 reduces the lesion area of southern corn leaf blight caused by B. maydis, and in field studies, concentrations of 300 and 500 mg/kg Iturin A-2 reduce the incidence of the disease. Iturin A-2 (12.5 µg/mL) inhibits cell division, but not nuclear division, in isolated fertilized starfish eggs .

HY-P3904

P34cdc2 Kinase Substrate Peptide	Biochemical Assay Reagents	Others
P34cdc2 Kinase Substrate Peptide is a synthetic peptide substrates for P34 ^cdc2 kinase, with a K_m of 74 μM for the purified human enzyme. P34cdc2 Kinase Substrate Peptide can be used in a rapid assay of P34 ^cdc2 phosphorylation in vitro. P34 ^cdc2, a protein serinehhreonine kinase, is a cell division cycle-regulated protein kinase .

Cat. No.	Product Name	Target	Research Area	Image

HY-P9980

Belantamab 2 Publications Verification GSK2857914	ADC Antibody TNF Receptor	Cancer
Belantamab (GSK2857916) is a humanized IgG1 anti-BCMA/TNFRSF17 monoclonal antibody. Belantamab is linked to MMAF (HY-15579) through a non-cleavable ADC linker to synthesize the antibody-active molecule conjugate (ADC) Belantamab mafodotin (HY-P3239). After binding to BCMA on the surface of tumor cells, Belantamab mafodotin enters the cell through receptor-mediated endocytosis. After entering the cell, Belantamab mafodotin releases MMAF, blocks cell division by inhibiting tubulin polymerization, arrests the cell cycle and induces cell apoptosis. Belantamab can be used for the study of multiple myeloma, especially relapsed/refractory multiple myeloma .

HY-P990673

Vandortuzumab DSTP-3086S Antibody; RG-7450 Antibody	ADC Antibody Transmembrane Glycoprotein Mitosis	Cancer
Vandortuzumab (DSTP-3086S Antibody; RG-7450 Antibody) is a humanized anti-STEAP1 IgG1 antibody and antimitotic agent that can be conjugated with MMAE (HY-15162) to form the antibody-drug conjugate (ADC) Vandortuzumab vedotin. Vandortuzumab vedotin specifically binds to STEAP1 and drives internalization of the complex, releasing the MMAE (HY-15162) payload intracellularly. After binding to tubulin, MMAE inhibits cell division and induces cell death. Vandortuzumab exhibits antitumor activity in preclinical xenograft models of prostate cancer and can be used for research related to metastatic castration-resistant prostate cancer (mCRPC) .

HY-P99528

Vandortuzumab vedotin DSTP 3086S; RG 7450; MSTP2109A	Antibody-Drug Conjugates (ADCs)	Cancer
Vandortuzumab vedotin (DSTP 3086S; RG 7450) is a STEAP1-targeted antibody-drug conjugate (ADC). Vandortuzumab vedotin binds specifically to STEAP1, triggers internalization of the conjugate complex, mediates intracellular release of monomethyl auristatin E, inhibits cell division, and induces cell death. Vandortuzumab vedotin exhibits antitumor activity in preclinical prostate cancer xenografts. Vandortuzumab vedotin can be used for the research of metastatic castration-resistant prostate cancer .

Species:	Human (61) E.coli (1)
Tag:	SUMO (2) His (42) Tag Free (12) Avi (4) GST (44) Flag (34)
Source:	sf9 insect cells (2) P. pastoris (1) Sf9 insect cells (56) E. coli (5)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P702693

	CDK13-CCNK Protein, Human (sf9, GST, Flag) CDK13; cyclin-dependent kinase 13; CDC2L5, cell division cycle 2 like 5 (cholinesterase related cell division controller); CDC2L; CHED; cholinesterase related cell division controller; KIAA1791; CDC2-related protein kinase 5; cell division protein kinase 13; cell division cycle 2-like protein kinase 5; cholinesterase-related cell division controller; CDC2L5; hCDK13; FLJ35215;	Human	Sf9 insect cells
	CDK13-CCNK Protein, Human (sf9, GST, Flag) is the recombinant human-derived CDK13-CCNK, expressed by Sf9 insect cells , with N-GST, N-Flag labeled tag. ,

HY-P702694

	CDK13-CCNT1 Protein, Human (Active, sf9, GST, Flag, His) CDK13; cyclin-dependent kinase 13; CDC2L5, cell division cycle 2 like 5 (cholinesterase related cell division controller); CDC2L; CHED; cholinesterase related cell division controller; KIAA1791; CDC2-related protein kinase 5; cell division protein kinase 13; cell division cycle 2-like protein kinase 5; cholinesterase-related cell division controller; CDC2L5; hCDK13; FLJ35215;	Human	Sf9 insect cells
	CDK13-CCNT1 Protein, Human (sf9, GST, Flag, His) is the recombinant human-derived CDK13-CCNT1, expressed by Sf9 insect cells , with N-His, N-Flag, N-GST labeled tag. ,

HY-P71495

	FtsZ Protein, E.coli (His-SUMO) ftsZ; c0113Cell division protein FtsZ	E.coli	E. coli
	FtsZ is an essential cell division protein that plays a central role in coordinating the formation of the contractile Z ring at the site of expected cell division. Precise regulation of the components of this ring is a key determinant, affecting the timing and location of cell division. FtsZ Protein, E.coli (His-SUMO) is the recombinant E. coli-derived FtsZ protein, expressed by E. coli , with N-SUMO, N-6*His labeled tag.

HY-P702736

	CDK1-CCNB1 Protein, Human (Active, sf9, GST, Flag, His) CDK1; cyclin-dependent kinase 1; CDC2, cell division cycle 2, G1 to S and G2 to M; CDC28A; p34 protein kinase; cell cycle controller CDC2; cell division protein kinase 1; cell division control protein 2 homolog; cell division cycle 2, G1 to S and G2 to M; CDC2; P34CDC2; MGC111195; DKFZp686L20222	Human	Sf9 insect cells
	The CDK1/CDC2-cyclin-B complex is a key regulator in the cell cycle. It plays an important role in cell division and development and regulates a variety of cellular activities, including chromosome segregation, nuclear membrane rupture, cytokinesis, etc. The activity of CDK1 is regulated by a variety of phosphorylation and dephosphorylation, thereby controlling the progression of the cell cycle and the DNA repair process. CDK1-CCNB1 Protein, Human (sf9, GST, Flag, His) is the recombinant human-derived CDK1-CCNB1, expressed by Sf9 insect cells, with N-GST, N-Flag, N-His labeled tag.

HY-P702671

	CDK1-CCNA2 Protein, Human (Active, sf9, GST, His) CDK1; cyclin-dependent kinase 1; CDC2, cell division cycle 2, G1 to S and G2 to M; CDC28A; p34 protein kinase; cell cycle controller CDC2; cell division protein kinase 1; cell division control protein 2 homolog; cell division cycle 2, G1 to S and G2 to M; CDC2; P34CDC2; MGC111195; DKFZp686L20222	Human	Sf9 insect cells
	The CDK1/CDC2-cyclin-B complex is a key regulator in the cell cycle. It plays an important role in cell division and development and regulates a variety of cellular activities, including chromosome segregation, nuclear membrane rupture, cytokinesis, etc. The activity of CDK1 is regulated by a variety of phosphorylation and dephosphorylation, thereby controlling the progression of the cell cycle and the DNA repair process. CDK1-CCNA2 Protein, Human (sf9, GST, His) is the recombinant human-derived CDK1-CCNA2, expressed by Sf9 insect cells, with N-His, N-GST labeled tag.

HY-P702674

	CDK1-CCNE2 Protein, Human (Active, sf9, GST, His, Flag) CDK1; cyclin-dependent kinase 1; CDC2, cell division cycle 2, G1 to S and G2 to M; CDC28A; p34 protein kinase; cell cycle controller CDC2; cell division protein kinase 1; cell division control protein 2 homolog; cell division cycle 2, G1 to S and G2 to M; CDC2; P34CDC2; MGC111195; DKFZp686L20222	Human	Sf9 insect cells
	The CDK1/CDC2-cyclin-B complex is a key regulator in the cell cycle. It plays an important role in cell division and development and regulates a variety of cellular activities, including chromosome segregation, nuclear membrane rupture, cytokinesis, etc. The activity of CDK1 is regulated by a variety of phosphorylation and dephosphorylation, thereby controlling the progression of the cell cycle and the DNA repair process. CDK1-CCNE2 Protein, Human (sf9, GST, His, Flag) is the recombinant human-derived CDK1-CCNE2, expressed by Sf9 insect cells, with N-His, N-GST, N-Flag labeled tag.

HY-P702673

	CDK1-CCNE1 Heterodimer Protein, Human (Active, sf9, GST, His, Flag) CDK1; cyclin-dependent kinase 1; CDC2, cell division cycle 2, G1 to S and G2 to M; CDC28A; p34 protein kinase; cell cycle controller CDC2; cell division protein kinase 1; cell division control protein 2 homolog; cell division cycle 2, G1 to S and G2 to M; CDC2; P34CDC2; MGC111195; DKFZp686L20222	Human	Sf9 insect cells
	The CDK1/CDC2-cyclin-B complex is a key regulator in the cell cycle. It plays an important role in cell division and development and regulates a variety of cellular activities, including chromosome segregation, nuclear membrane rupture, cytokinesis, etc. The activity of CDK1 is regulated by a variety of phosphorylation and dephosphorylation, thereby controlling the progression of the cell cycle and the DNA repair process. CDK1-CCNE1 Heterodimer Protein, Human (sf9, GST, His, Flag) is the recombinant human-derived CDK1-CCNE1, expressed by Sf9 insect cells, with N-GST, N-Flag, N-His labeled tag.

HY-P704529

	CDK5 Protein, Human (His-SUMO) Cdk5; Cell division protein kinase 5; Protein kinase CDK5 splicing; PSSALRE	Human	E. coli
	CDK5 is a proline-directed serine/threonine protein kinase that critically regulates neuronal cell cycle, differentiation and potential apoptosis in neuronal diseases by preventing cell cycle re-entry. It interacts with numerous proteins involved in neuronal development and coordinates processes such as survival, migration, differentiation, axonal growth, synaptogenesis, and neurotransmission. CDK5 Protein, Human (His-SUMO) is the recombinant human-derived CDK5 protein, expressed by E. coli, with N-6*His and N-SUMO labeled tag.

HY-P702860

	CDK4 Protein, Human (sf9, His, Avi) CDK4; Cell division protein kinase 4; CMM3; PSK-J3	Human	Sf9 insect cells
	CDK4 protein, acting as a Ser/Thr kinase in the cyclin D-CDK4 complex, critically regulates the G(1)/S transition by phosphorylating and inhibiting RB family members. This activity, specifically hypophosphorylation of RB1 during early G(1) phase, releases E2F and promotes transcription of genes that drive G(1) progression. CDK4 Protein, Human (sf9, His, Avi) is the recombinant human-derived CDK4, expressed by Sf9 insect cells, with N-Avi, N-His labeled tag. The total length of CDK4 Protein, Human (sf9, His, Avi) is 303 a.a..

HY-P72298

	CDK5 Protein, Human (P.pastoris, His) Cdk5; Cell division protein kinase 5; Protein kinase CDK5 splicing; PSSALRE	Human	P. pastoris
	CDK5 is a proline-directed serine/threonine protein kinase that critically regulates neuronal cell cycle, differentiation and potential apoptosis in neuronal diseases by preventing cell cycle re-entry. It interacts with numerous proteins involved in neuronal development and coordinates processes such as survival, migration, differentiation, axonal growth, synaptogenesis, and neurotransmission. CDK5 Protein, Human (P.pastoris, His) is the recombinant human-derived CDK5 protein, expressed by P. pastoris , with N-His labeled tag.

HY-P705802

	CDK5 Protein, Human (sf9, GST) Cdk5; Cell division protein kinase 5; Protein kinase CDK5 splicing; PSSALRE	Human	sf9 insect cells

HY-P701374

	CDK9-CCNK Heterodimer Protein, Human (sf9) CDK9; CCNK; Cyclin-dependent kinase 9; C-2K; Cell division cycle 2-like protein kinase 4; Cell division protein kinase 9; Serine/threonine-protein kinase PITALRE; Tat-associated kinase complex catalytic subunit; Cyclin-K	Human	Sf9 insect cells
	The CDK9 protein plays a central role in transcriptional regulation, promoting the transition from ineffective to efficient elongation by phosphorylating POLR2A, SUPT5H, and RDBP. As part of the CDK9/cyclin-T complex, it participates in phosphorylation events affecting EP300, MYOD1, RPB1/POLR2A, AR, DSIF, and NELFE. CDK9-CCNK Heterodimer Protein, Human (sf9) is a recombinant protein dimer complex containing human-derived CDK9-CCNK Heterodimer protein, expressed by sf9 insect cells , with tag free.

HY-P704003

	CDK4 Protein, Human (sf9, His, Flag, Avi) CDK4; Cell division protein kinase 4; CMM3; PSK-J3	Human	Sf9 insect cells
	CDK4 protein, acting as a Ser/Thr kinase in the cyclin D-CDK4 complex, critically regulates the G(1)/S transition by phosphorylating and inhibiting RB family members. This activity, specifically hypophosphorylation of RB1 during early G(1) phase, releases E2F and promotes transcription of genes that drive G(1) progression. CDK4 Protein, Human (sf9, His, Flag, Avi) is the recombinant human-derived CDK4 protein, expressed by Sf9 insect cells, with Avi and N-His and N-Flag labeled tag.

HY-P704540

	CDC42 Protein, Human (Active, GST-His) CDC42; Cell division control protein 42 homolog; G25K GTP-binding protein	Human	E. coli
	CDC42 is a plasma membrane-associated small GTPase that regulates cellular responses by cycling between an active GTP-bound state and an inactive GDP-bound state. It participates in epithelial cell polarization, regulates the attachment of spindle microtubules to kinetochores, affects cell migration, and plays a key role in the formation of filopodia. CDC42 Protein, Human (Active, GST-His) is the recombinant human-derived CDC42 protein, expressed by E. coli, with N-His and N-GST labeled tag.

HY-P701375

	CDK9-CCNK Heterodimer Protein, Human (Active, sf9, GST, FLAG) CDK9; CCNK; Cyclin-dependent kinase 9; C-2K; Cell division cycle 2-like protein kinase 4; Cell division protein kinase 9; Serine/threonine-protein kinase PITALRE; Tat-associated kinase complex catalytic subunit; Cyclin-K	Human	Sf9 insect cells
	The CDK9 protein plays a central role in transcriptional regulation, promoting the transition from ineffective to efficient elongation by phosphorylating POLR2A, SUPT5H, and RDBP. As part of the CDK9/cyclin-T complex, it participates in phosphorylation events affecting EP300, MYOD1, RPB1/POLR2A, AR, DSIF, and NELFE. CDK9-CCNK Heterodimer Protein, Human (sf9, GST, FLAG) is a recombinant protein dimer complex containing human-derived CDK9-CCNK Heterodimer protein, expressed by sf9 insect cells , with N-Flag, N-GST labeled tag.

HY-P701360

	CDK12-CCNK Heterodimer Protein, Human (sf9) CDK12; CCNK; Cyclin-dependent kinase 12; Cdc2-related kinase; arginine/serine-rich; CrkRS; Cell division cycle 2-related protein kinase 7; CDC2-related protein kinase 7; Cell division protein kinase 12; hCDK12; Cyclin-K	Human	Sf9 insect cells
	The CDK12 protein is a cyclin-dependent kinase that critically phosphorylates the C-terminal domain of POLR2A, thereby regulating transcription elongation. It selectively targets "Ser-5" phosphorylated at "Ser-7" in the CTD repeat and can also target "Ser-2". CDK12-CCNK Heterodimer Protein, Human (sf9) is a recombinant protein dimer complex containing human-derived CDK12-CCNK Heterodimer protein, expressed by sf9 insect cells , with tag free.

HY-P701377

	CDK9-CCNT2 Heterodimer Protein, Human (sf9) CDK9; CCNT2; Cyclin-dependent kinase 9; C-2K; Cell division cycle 2-like protein kinase 4; Cell division protein kinase 9; Serine/threonine-protein kinase PITALRE; Tat-associated kinase complex catalytic subunit; Cyclin-T2; CycT2	Human	Sf9 insect cells
	The CDK9 protein plays a central role in transcriptional regulation, promoting the transition from ineffective to efficient elongation by phosphorylating POLR2A, SUPT5H, and RDBP. As part of the CDK9/cyclin-T complex, it participates in phosphorylation events affecting EP300, MYOD1, RPB1/POLR2A, AR, DSIF, and NELFE. CDK9-CCNT2 Heterodimer Protein, Human (sf9) is a recombinant protein dimer complex containing human-derived CDK9-CCNT2 Heterodimer protein, expressed by sf9 insect cells , with tag free.

HY-P702689

	CDK9-CCNT1 Heterodimer Protein, Human (Active, sf9, GST, His) CDK9; CCNK; Cyclin-dependent kinase 9; C-2K; Cell division cycle 2-like protein kinase 4; Cell division protein kinase 9; Serine/threonine-protein kinase PITALRE; Tat-associated kinase complex catalytic subunit; Cyclin-K	Human	Sf9 insect cells
	The CDK9 protein plays a central role in transcriptional regulation, promoting the transition from ineffective to efficient elongation by phosphorylating POLR2A, SUPT5H, and RDBP. As part of the CDK9/cyclin-T complex, it participates in phosphorylation events affecting EP300, MYOD1, RPB1/POLR2A, AR, DSIF, and NELFE. CDK9-CCNT1 Heterodimer Protein, Human (sf9, GST, His) is the recombinant human-derived CDK9-CCNT1, expressed by Sf9 insect cells, with N-His, N-GST labeled tag.

HY-P702690

	CDK9-CCNT2 Heterodimer Protein, Human (Active, sf9, GST, Flag, His) CDK9; CCNK; Cyclin-dependent kinase 9; C-2K; Cell division cycle 2-like protein kinase 4; Cell division protein kinase 9; Serine/threonine-protein kinase PITALRE; Tat-associated kinase complex catalytic subunit; Cyclin-K	Human	Sf9 insect cells
	The CDK9 protein plays a central role in transcriptional regulation, promoting the transition from ineffective to efficient elongation by phosphorylating POLR2A, SUPT5H, and RDBP. As part of the CDK9/cyclin-T complex, it participates in phosphorylation events affecting EP300, MYOD1, RPB1/POLR2A, AR, DSIF, and NELFE. CDK9-CCNT2 Heterodimer Protein, Human (sf9, GST, Flag, His) is the recombinant human-derived CDK9-CCNT2, expressed by Sf9 insect cells, with N-His, N-GST, N-Flag labeled tag.

HY-P701361

	CDK12-CCNK Heterodimer Protein, Human (Active, sf9, GST, FLAG) CDK12; CCNK; Cyclin-dependent kinase 12; Cdc2-related kinase; arginine/serine-rich; CrkRS; Cell division cycle 2-related protein kinase 7; CDC2-related protein kinase 7; Cell division protein kinase 12; hCDK12; Cyclin-K	Human	Sf9 insect cells
	The CDK12 protein is a cyclin-dependent kinase that critically phosphorylates the C-terminal domain of POLR2A, thereby regulating transcription elongation. It selectively targets "Ser-5" phosphorylated at "Ser-7" in the CTD repeat and can also target "Ser-2". CDK12-CCNK Heterodimer Protein, Human (sf9, GST, FLAG) is a recombinant protein dimer complex containing human-derived CDK12-CCNK Heterodimer protein, expressed by sf9 insect cells , with N-Flag, N-GST labeled tag.

HY-P701376

	CDK9-CCNT1 Heterodimer Protein, Human (Active, sf9) CDK9; CCNT1; Cyclin-dependent kinase 9; C-2K; Cell division cycle 2-like protein kinase 4; Cell division protein kinase 9; Serine/threonine-protein kinase PITALRE; Tat-associated kinase complex catalytic subunit; Cyclin-T1; CycT1; Cyclin-T	Human	Sf9 insect cells
	The CDK9 protein plays a central role in transcriptional regulation, promoting the transition from ineffective to efficient elongation by phosphorylating POLR2A, SUPT5H, and RDBP. As part of the CDK9/cyclin-T complex, it participates in phosphorylation events affecting EP300, MYOD1, RPB1/POLR2A, AR, DSIF, and NELFE. CDK9-CCNT1 Heterodimer Protein, Human (sf9) is a recombinant protein dimer complex containing human-derived CDK9-CCNT1 Heterodimer protein, expressed by sf9 insect cells , with tag free.

HY-P702692

	CDK12-CCNT1 Protein, Human (Active, sf9, GST, Flag, His) CDK12; CCNK; Cyclin-dependent kinase 12; Cdc2-related kinase; arginine/serine-rich; CrkRS; Cell division cycle 2-related protein kinase 7; CDC2-related protein kinase 7; Cell division protein kinase 12; hCDK12; Cyclin-K	Human	Sf9 insect cells
	The CDK12 protein is a cyclin-dependent kinase that critically phosphorylates the C-terminal domain of POLR2A, thereby regulating transcription elongation. It selectively targets "Ser-5" phosphorylated at "Ser-7" in the CTD repeat and can also target "Ser-2". CDK12-CCNT1 Protein, Human (sf9, GST, Flag, His) is the recombinant human-derived CDK12-CCNT1, expressed by Sf9 insect cells, with N-His, N-GST, N-Flag labeled tag.

HY-P706016

	CDK12-CCNK Heterodimer Protein, Human (Active, sf9, His-GST) CDK12; CCNK; Cyclin-dependent kinase 12; Cdc2-related kinase; arginine/serine-rich; CrkRS; Cell division cycle 2-related protein kinase 7; CDC2-related protein kinase 7; Cell division protein kinase 12; hCDK12; Cyclin-K	Human	Sf9 insect cells
	The CDK12 protein is a cyclin-dependent kinase that critically phosphorylates the C-terminal domain of POLR2A, thereby regulating transcription elongation. It selectively targets "Ser-5" phosphorylated at "Ser-7" in the CTD repeat and can also target "Ser-2". CDK12-CCNK Heterodimer Protein, Human (sf9) is a recombinant protein dimer complex containing human-derived CDK12-CCNK Heterodimer protein, expressed by sf9 insect cells , with tag free.

HY-P702601

	CDK6 Protein, Human (sf9, His-Avi) 1 Publications Verification Cyclin-dependent kinase 6; Cell division protein kinase 6; CDKN6; EC:2.7.11.22	Human	Sf9 insect cells
	The CDK6ic complex is an important serine/threonine protein kinase that regulates cell cycle progression and differentiation, promoting the G1/S transition by phosphorylating substrates such as pRB/RB1 and NPM1. It interacts with D-type G1 cyclins during interphase to form active pRB/RB1 kinase, which controls cell cycle entry. CDK6 Protein, Human (Sf9, His-Avi) is the recombinant human-derived CDK6, expressed by Sf9 insect cells, with N-His, N-Avi labeled tag. The total length of CDK6 Protein, Human (Sf9, His-Avi) is 326 a.a..

HY-P70014

	CDK2 Protein, Human (His) rHuCyclin-dependent kinase 2/CDK2, His; Cyclin-Dependent Kinase 2; Cell Division Protein Kinase 2; p33 Protein Kinase; CDK2; CDKN2	Human	E. coli
	CDK2 is an important serine/threonine protein kinase that plays a critical regulatory role in the cell cycle, especially during meiosis. It phosphorylates various substrates (CTNNB1, USP37, p53/TP53, NPM1, CDK7, RB1, BRCA2, MYC, NPAT, EZH2) and coordinates centrosome duplication and initiation of DNA synthesis at the G1-S transition. CDK2 Protein, Human (His) is the recombinant human-derived CDK2 protein, expressed by E. coli , with N-6*His labeled tag.

HY-P701364

	CDK3-CCNE1 Heterodimer Protein, Human (sf9) CDK3; CCNE1; Cyclin-dependent kinase 3; Cell division protein kinase 3; G1/S-specific cyclin-E1	Human	Sf9 insect cells
	CDK3 protein is a serine/threonine protein kinase that plays a key role in regulating the eukaryotic cell cycle, especially affecting the G0-G1 and G1-S transitions. It interacts with CCNC/cyclin-C during interphase and phosphorylates substrates such as histone H1, ATF1, RB1, and CABLES1. CDK3-CCNE1 Heterodimer Protein, Human (sf9) is a recombinant protein dimer complex containing human-derived CDK3-CCNE1 Heterodimer protein, expressed by sf9 insect cells , with tag free.

HY-P705800

	CDK2 Protein, Human (sf9) rHuCyclin-dependent kinase 2/CDK2, His; Cyclin-Dependent Kinase 2; Cell Division Protein Kinase 2; p33 Protein Kinase; CDK2; CDKN2	Human	sf9 insect cells

HY-P702680

	CDK3-CCNC Protein, Human (Active, sf9, GST, Flag, His) CDK3; CCNE1; Cyclin-dependent kinase 3; Cell division protein kinase 3; G1/S-specific cyclin-E1	Human	Sf9 insect cells
	CDK3 protein is a serine/threonine protein kinase that plays a key role in regulating the eukaryotic cell cycle, especially affecting the G0-G1 and G1-S transitions. It interacts with CCNC/cyclin-C during interphase and phosphorylates substrates such as histone H1, ATF1, RB1, and CABLES1. CDK3-CCNC Protein, Human (Active, sf9, GST, Flag, His) is the recombinant human-derived CDK3-CCNC, expressed by Sf9 insect cells, with N-Flag, N-His, N-GST labeled tag.

HY-P702681

	CDK3-CCNE2 Protein, Human (sf9, GST, Flag, His) CDK3; CCNE1; Cyclin-dependent kinase 3; Cell division protein kinase 3; G1/S-specific cyclin-E1	Human	Sf9 insect cells
	CDK3 protein is a serine/threonine protein kinase that plays a key role in regulating the eukaryotic cell cycle, especially affecting the G0-G1 and G1-S transitions. It interacts with CCNC/cyclin-C during interphase and phosphorylates substrates such as histone H1, ATF1, RB1, and CABLES1. CDK3-CCNE2 Protein, Human (sf9, GST, Flag, His) is the recombinant human-derived CDK3-CCNE2, expressed by Sf9 insect cells, with N-His, N-GST, N-Flag labeled tag.

HY-P705801

	CDK2 Protein, Human (Biotinylated, His-Avi) rHuCyclin-dependent kinase 2/CDK2, His; Cyclin-Dependent Kinase 2; Cell Division Protein Kinase 2; p33 Protein Kinase; CDK2; CDKN2	Human	E. coli

HY-P706030

	CDK3-CCNH Protein, Human (Active, sf9, His, GST) Cyclin-dependent kinase 3; Cell division protein kinase 3; CDKN3; Cyclin-H; MO15-associated protein; p34; p37	Human	Sf9 insect cells

HY-P702684

	CDK4-CCND3 Protein, Human (Active, sf9, GST, His) CDK4; cyclin-dependent kinase 4; PSK J3; cell division protein kinase 4; CMM3; PSK-J3; MGC14458;	Human	Sf9 insect cells
	CDK4 protein, acting as a Ser/Thr kinase in the cyclin D-CDK4 complex, critically regulates the G(1)/S transition by phosphorylating and inhibiting RB family members. This activity, specifically hypophosphorylation of RB1 during early G(1) phase, releases E2F and promotes transcription of genes that drive G(1) progression. CDK4-CCND3 Protein, Human (sf9, GST, His) is the recombinant human-derived CDK4-CCND3, expressed by Sf9 insect cells, with N-His, N-GST labeled tag.

HY-P702699

	CDK19-CCNC-MED12 Protein, Human (Active, sf9, GST, Flag, His) CDC2L6; CDK19; cyclin dependent kinase 19; CDK11; CDC2L6; bA346C16.3; cyclin-dependent kinase 19; CDC2-related protein kinase 6; CDK8-like cyclin-dependent kinase; cell division cycle 2-like 6 (CDK8-like); cell division cycle 2-like protein kinase 6; cell division protein kinase 19; cyclin dependent kinase 19 variant 2; cyclin-dependent kinase (CDC2-like) 11; cyclin-dependent kinase 11; death-preventing kinase; EC 2.7.11.22	Human	Sf9 insect cells
	CDK19 plays a key role in cellular homeostasis and developmental programming. CDK19 can interact with p53 to inhibit p53-mediated transcription of p21, and regulates the proliferation of hematopoietic stem cells and acute myeloid leukemia cells. Besides, CDK19 is the paralog of CDK8. CDK8 and CDK19 can cooperate with each other in stimulating NFκB-induced transcription and Dengue virus replication. CDK19-CCNC-MED12 Protein, Human (sf9, GST, Flag, His) is the recombinant human-derived CDK19-CCNC-MED12, expressed by Sf9 insect cells, with N-6*His, N-GST, N-Flag labeled tag.

HY-P702682

	CDK4-CCND1 Protein, Human (Active, sf9, GST, Flag, His) 1 Publications Verification CDK4; cyclin-dependent kinase 4; PSK J3; cell division protein kinase 4; CMM3; PSK-J3; MGC14458;	Human	Sf9 insect cells
	CDK4 protein, acting as a Ser/Thr kinase in the cyclin D-CDK4 complex, critically regulates the G(1)/S transition by phosphorylating and inhibiting RB family members. This activity, specifically hypophosphorylation of RB1 during early G(1) phase, releases E2F and promotes transcription of genes that drive G(1) progression. CDK4-CCND1 Protein, Human (sf9, GST, Flag, His) is the recombinant human-derived CDK4-CCND1, expressed by Sf9 insect cells, with N-His, N-GST, N-Flag labeled tag.

HY-P702683

	CDK4-CCND2 Protein, Human (Active, sf9, GST, Flag, His) CDK4; cyclin-dependent kinase 4; PSK J3; cell division protein kinase 4; CMM3; PSK-J3; MGC14458;	Human	Sf9 insect cells
	CDK4 protein, acting as a Ser/Thr kinase in the cyclin D-CDK4 complex, critically regulates the G(1)/S transition by phosphorylating and inhibiting RB family members. This activity, specifically hypophosphorylation of RB1 during early G(1) phase, releases E2F and promotes transcription of genes that drive G(1) progression. CDK4-CCND2 Protein, Human (sf9, GST, Flag, His) is the recombinant human-derived CDK4-CCND2, expressed by Sf9 insect cells, with N-His, N-GST, N-Flag labeled tag.

HY-P701365

	CDK3-CCNE1 Heterodimer Protein, Human (Active, sf9, GST, FLAG, His) CDK3; CCNE1; Cyclin-dependent kinase 3; Cell division protein kinase 3; G1/S-specific cyclin-E1	Human	Sf9 insect cells
	CDK3 protein is a serine/threonine protein kinase that plays a key role in regulating the eukaryotic cell cycle, especially affecting the G0-G1 and G1-S transitions. It interacts with CCNC/cyclin-C during interphase and phosphorylates substrates such as histone H1, ATF1, RB1, and CABLES1. CDK3-CCNE1 Heterodimer Protein, Human (sf9, GST, FLAG, His) is a recombinant protein dimer complex containing human-derived CDK3-CCNE1 Heterodimer protein, expressed by sf9 insect cells , with N-6*His, N-Flag, N-GST labeled tag.

HY-P701369

	CDK6-CCND3 Heterodimer Protein, Human (sf9) CDK6; CCND3; Cyclin-dependent kinase 6; Cell division protein kinase 6; Serine/threonine-protein kinase PLSTIRE; G1/S-specific cyclin-D3	Human	Sf9 insect cells
	The CDK6ic complex is an important serine/threonine protein kinase that regulates cell cycle progression and differentiation, promoting the G1/S transition by phosphorylating substrates such as pRB/RB1 and NPM1. It interacts with D-type G1 cyclins during interphase to form active pRB/RB1 kinase, which controls cell cycle entry. CDK6-CCND3 Heterodimer Protein, Human (sf9) is a recombinant protein dimer complex containing human-derived CDK6-CCND3 Heterodimer protein, expressed by sf9 insect cells , with tag free.

HY-P701370

	CDK6-CCND3 Heterodimer Protein, Human (Active, sf9, GST, His) CDK6; CCND3; Cyclin-dependent kinase 6; Cell division protein kinase 6; Serine/threonine-protein kinase PLSTIRE; G1/S-specific cyclin-D3	Human	Sf9 insect cells
	The CDK6ic complex is an important serine/threonine protein kinase that regulates cell cycle progression and differentiation, promoting the G1/S transition by phosphorylating substrates such as pRB/RB1 and NPM1. It interacts with D-type G1 cyclins during interphase to form active pRB/RB1 kinase, which controls cell cycle entry. CDK6-CCND3 Heterodimer Protein, Human (sf9, GST, His) is a recombinant protein dimer complex containing human-derived CDK6-CCND3 Heterodimer protein, expressed by sf9 insect cells , with N-10*His, N-GST labeled tag.

HY-P703459

	CDK2/CCNE2 Protein, Sus scrofa (Active, sf9, GST, His, Flag) Cyclin-dependent kinase 2; Cell division protein kinase 2; CDK2; Sus scrofa; Pig; Kinase; Serine/threonine-protein kinase; Transferase; 2.7.11.22	Others	Sf9 insect cells
	CDK2/CCNE2 Protein, Sus scrofa (sf9, GST, His, Flag) is the recombinant CDK2/CCNE2, expressed by sf9 insect cells , with His, GST, Flag labeled tag.

HY-P703475

	CDK2-CCNE1 Protein, Sus scrofa (Active, sf9, GST, His, Flag) Cyclin-dependent kinase 2; Cell division protein kinase 2; CDK2; Sus scrofa; Pig; Kinase; Serine/threonine-protein kinase; Transferase; 2.7.11.22	Others	Sf9 insect cells

HY-P706028

	CDK11B(p110)-CCNL2-SAP30BP Complex Protein, Human (Active, sf9, His-GST, Flag) Cyclin-dependent kinase 11B; Cell division cycle 2-like protein kinase 1; CLK-1; Cell division protein kinase 11B; Galactosyltransferase-associated protein kinase p58/GTA; PITSLRE serine/threonine-protein kinase CDC2L1; p58 CLK-1; CDC2L1; CDK11; PITSLREA; Cyclin-L2; Paneth cell-enhanced expression protein; SAP30-binding protein; Transcriptional regulator protein HCNGP; HCNGP; HTRG; HTRP	Human	Sf9 insect cells

HY-P706029

	CDK11B(p58)-CCNL2-SAP30BP Complex Protein, Human (Active, sf9, His-GST, Flag) Cyclin-dependent kinase 11B; Cell division cycle 2-like protein kinase 1; CLK-1; Cell division protein kinase 11B; Galactosyltransferase-associated protein kinase p58/GTA; PITSLRE serine/threonine-protein kinase CDC2L1; p58 CLK-1; CDC2L1; CDK11; PITSLREA; Cyclin-L2; Paneth cell-enhanced expression protein; SAP30-binding protein; Transcriptional regulator protein HCNGP; HCNGP; HTRG; HTRP	Human	Sf9 insect cells

HY-P702687

	CDK6-CCND1 Heterodimer Protein, Human (Active, sf9, GST, Flag, His) 1 Publications Verification CDK6; CCND2; Cyclin-dependent kinase 6; Cell division protein kinase 6; Serine/threonine-protein kinase PLSTIRE; G1/S-specific cyclin-D2	Human	Sf9 insect cells
	The CDK6ic complex is an important serine/threonine protein kinase that regulates cell cycle progression and differentiation, promoting the G1/S transition by phosphorylating substrates such as pRB/RB1 and NPM1. It interacts with D-type G1 cyclins during interphase to form active pRB/RB1 kinase, which controls cell cycle entry. CDK6-CCND1 Heterodimer Protein, Human (sf9, GST, Flag, His) is the recombinant human-derived CDK6-CCND1 Heterodimer, expressed by Sf9 insect cells, with N-Flag, N-His, N-GST labeled tag.

HY-P701368

	CDK6-CCND2 Heterodimer Protein, Human (Active, sf9, GST, FLAG, His) CDK6; CCND2; Cyclin-dependent kinase 6; Cell division protein kinase 6; Serine/threonine-protein kinase PLSTIRE; G1/S-specific cyclin-D2	Human	Sf9 insect cells
	The CDK6ic complex is an important serine/threonine protein kinase that regulates cell cycle progression and differentiation, promoting the G1/S transition by phosphorylating substrates such as pRB/RB1 and NPM1. It interacts with D-type G1 cyclins during interphase to form active pRB/RB1 kinase, which controls cell cycle entry. CDK6-CCND2 Heterodimer Protein, Human (sf9, GST, FLAG, His) is a recombinant protein dimer complex containing human-derived CDK6-CCND2 Heterodimer protein, expressed by sf9 insect cells , with N-Flag, N-8*His, N-GST labeled tag.

HY-P702675

	CDK2-CCNA2 Protein, Human (Active, sf9, GST, His) CDK2; cyclin-dependent kinase 2; p33 protein kinase; cell devision kinase 2; cdc2-related protein kinase; cell division protein kinase 2; p33(CDK2)	Human	Sf9 insect cells
	CDK2 is an important serine/threonine protein kinase that plays a critical regulatory role in the cell cycle, especially during meiosis. It phosphorylates various substrates (CTNNB1, USP37, p53/TP53, NPM1, CDK7, RB1, BRCA2, MYC, NPAT, EZH2) and coordinates centrosome duplication and initiation of DNA synthesis at the G1-S transition. CDK2-CCNA2 Protein, Human (sf9, GST, His) is the recombinant human-derived CDK2-CCNA2, expressed by Sf9 insect cells, with N-6*His, N-GST labeled tag.

HY-P702679

	CDK2-CCNO Protein, Human (Active, sf9, GST, Flag, His) CDK2; cyclin-dependent kinase 2; p33 protein kinase; cell devision kinase 2; cdc2-related protein kinase; cell division protein kinase 2; p33(CDK2)	Human	Sf9 insect cells
	CDK2 is an important serine/threonine protein kinase that plays a critical regulatory role in the cell cycle, especially during meiosis. It phosphorylates various substrates (CTNNB1, USP37, p53/TP53, NPM1, CDK7, RB1, BRCA2, MYC, NPAT, EZH2) and coordinates centrosome duplication and initiation of DNA synthesis at the G1-S transition. CDK2-CCNO Protein, Human (sf9, GST, Flag, His) is the recombinant human-derived CDK2-CCNO, expressed by Sf9 insect cells, with N-GST, N-Flag, N-His labeled tag.

HY-P702676

	CDK2-CCND1 Protein, Human (Active, sf9, GST, Flag, His) CDK2; cyclin-dependent kinase 2; p33 protein kinase; cell devision kinase 2; cdc2-related protein kinase; cell division protein kinase 2; p33(CDK2)	Human	Sf9 insect cells
	CDK2 is an important serine/threonine protein kinase that plays a critical regulatory role in the cell cycle, especially during meiosis. It phosphorylates various substrates (CTNNB1, USP37, p53/TP53, NPM1, CDK7, RB1, BRCA2, MYC, NPAT, EZH2) and coordinates centrosome duplication and initiation of DNA synthesis at the G1-S transition. CDK2-CCND1 Protein, Human (sf9, GST, Flag, His) is the recombinant human-derived CDK2-CCND1, expressed by Sf9 insect cells, with N-His, N-GST, N-Flag labeled tag.

HY-P702677

	CDK2-CCNE1 Protein, Human (Active, sf9, GST, His, Flag) CDK2; cyclin-dependent kinase 2; p33 protein kinase; cell devision kinase 2; cdc2-related protein kinase; cell division protein kinase 2; p33(CDK2)	Human	Sf9 insect cells
	CDK2 is an important serine/threonine protein kinase that plays a critical regulatory role in the cell cycle, especially during meiosis. It phosphorylates various substrates (CTNNB1, USP37, p53/TP53, NPM1, CDK7, RB1, BRCA2, MYC, NPAT, EZH2) and coordinates centrosome duplication and initiation of DNA synthesis at the G1-S transition. CDK2-CCNE1 Protein, Human (sf9, GST, His, Flag) is the recombinant human-derived CDK2-CCNE1, expressed by Sf9 insect cells, with N-His, N-GST, N-Flag labeled tag.

HY-P702685

	CDK5-p25 Protein, Human (Active, sf9, GST, His, Flag) CDK5; cyclin-dependent kinase 5; PSSALRE; TPKII catalytic subunit; protein kinase CDK5 splicing; cell division protein kinase 5; serine/threonine-protein kinase PSSALRE; tau protein kinase II catalytic subunit;	Human	Sf9 insect cells
	CDK5 is a proline-directed serine/threonine protein kinase that critically regulates neuronal cell cycle, differentiation and potential apoptosis in neuronal diseases by preventing cell cycle re-entry. It interacts with numerous proteins involved in neuronal development and coordinates processes such as survival, migration, differentiation, axonal growth, synaptogenesis, and neurotransmission. CDK5-p25 Protein, Human (sf9, GST, His, Flag) is the recombinant human-derived CDK5-p25, expressed by Sf9 insect cells, with N-GST, N-His, N-Flag labeled tag.

HY-P702678

	CDK2-CCNE2 Protein, Human (Active, sf9, GST, Flag, His) CDK2; cyclin-dependent kinase 2; p33 protein kinase; cell devision kinase 2; cdc2-related protein kinase; cell division protein kinase 2; p33(CDK2)	Human	Sf9 insect cells
	CDK2 is an important serine/threonine protein kinase that plays a critical regulatory role in the cell cycle, especially during meiosis. It phosphorylates various substrates (CTNNB1, USP37, p53/TP53, NPM1, CDK7, RB1, BRCA2, MYC, NPAT, EZH2) and coordinates centrosome duplication and initiation of DNA synthesis at the G1-S transition. CDK2-CCNE2 Protein, Human (sf9, GST, Flag, His) is the recombinant human-derived CDK2-CCNE2, expressed by Sf9 insect cells, with N-His, N-GST, N-Flag labeled tag.

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Host:	Mouse (5) Rabbit (32)
Reactivity:	Human (37) Rat (18) Mouse (17) Monkey (2) Hamster (2)
Application:	IHC-P (20) ICC/IF (16) IF-Tissue (1) IP (10) WB (33) FC (7) Dot Blot (1) ELISA (5)
Isotype:	IgG (32) IgG1 (1)
Conjugation:	Non-conjugated (37) Biotin (1)
Clonality:	Polyclonal (1) Monoclonal (26) Recombinant (16)
Modification:	Phosphorylated (4) Unmodified (23)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P82864

	CDCA5 Antibody (YA2609) CDCA5; Cell division cycle associated protein 5; Cell division cycle-associated protein 5; p35; Sororin	WB, IHC-P, ICC/IF, FC	Human
	CDCA5 Antibody (YA2609) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CDCA5.

HY-P84958

	CDC123 Antibody (YA4650) C10orf7 antibody; CD123_HUMAN antibody; CDC123 antibody; Cell division cycle 123 antibody; Cell division cycle 123 homolog antibody; Cell division cycle protein 123 homolog antibody; D123 antibody; HT 1080 antibody; HT-1080 antibody; Protein D123 antibody; PZ32 antibody;	WB, FC	Human, Mouse, Rat
	CDC123 Antibody (YA4650) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CDC123.

HY-P84958A

	CDC123 Antibody (YA4650)(PBS only) C10orf7 antibody; CD123_HUMAN antibody; CDC123 antibody; Cell division cycle 123 antibody; Cell division cycle 123 homolog antibody; Cell division cycle protein 123 homolog antibody; D123 antibody; HT 1080 antibody; HT-1080 antibody; Protein D123 antibody; PZ32 antibody;	WB, FC	Human, Mouse, Rat
	CDC123 Antibody (YA4650) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CDC123.

HY-P80611

	CDK1 Antibody (YA516) 2 Publications Verification CDK1; CDC2; CDC28A; CDKN1; P34CDC2; Cyclin-dependent kinase 1; CDK1; Cell division control protein 2 homolog; Cell division protein kinase 1; p34 protein kinase	WB, IP	Human
	CDK1 Antibody (YA516) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CDK1.

HY-P86404

	CDK1 Antibody (YA6096) CDK1; CDC2; CDC28A; CDKN1; P34CDC2; Cyclin-dependent kinase 1; CDK1; Cell division control protein 2 homolog; Cell division protein kinase 1; p34 protein kinase	WB, IHC-P, ICC/IF, IP, ELISA	Human, Mouse
	CDK1 Antibody (YA6096) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CDK1.

HY-P80796

	Phospho-CDK1 (Tyr15) Antibody CDK1; CDC2; CDC28A; CDKN1; P34CDC2; Cyclin-dependent kinase 1; CDK1; Cell division control protein 2 homolog; Cell division protein kinase 1; p34 protein kinase	WB	Human, Mouse, Rat
	Phospho-CDK1 (Tyr15) Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to Phospho-CDK1 (Tyr15).

HY-P810642

	Phospho-CDK (Tyr15) Antibody (YA9904) CDK1; CDC2; CDC28A; CDKN1; P34CDC2; Cyclin-dependent kinase 1; CDK1; Cell division control protein 2 homolog; Cell division protein kinase 1; p34 protein kinase	WB, IHC-P	Human, Mouse
	Phospho-CDK (Tyr15) Antibody (YA9904) is a Rabbit-derived and non-conjugated IgG Recombinant, Monoclonal antibody, targeting to Phospho-CDK (Tyr15).

HY-P80611A

	CDK1 Antibody (YA516)(PBS only) CDK1; CDC2; CDC28A; CDKN1; P34CDC2; Cyclin-dependent kinase 1; CDK1; Cell division control protein 2 homolog; Cell division protein kinase 1; p34 protein kinase	WB, IP	Human
	CDK1 Antibody (YA516) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CDK1.

HY-P810643

	Phospho-CDK1 (Thr161) Antibody (YA9905) CDK1; CDC2; CDC28A; CDKN1; P34CDC2; Cyclin-dependent kinase 1; CDK1; Cell division control protein 2 homolog; Cell division protein kinase 1; p34 protein kinase	WB, ICC/IF, IHC-P, FC	Human, Mouse, Rat
	Phospho-CDK1 (Thr161) Antibody (YA9905) is a Rabbit-derived and non-conjugated IgG Recombinant, Monoclonal antibody, targeting to Phospho-CDK1 (Thr161).

HY-P85098

	CDK9 Antibody (YA4790) CDK9; CDC2L4; TAK; Cyclin-dependent kinase 9; C-2K; Cell division cycle 2-like protein kinase 4; Cell division protein kinase 9; Serine/threonine-protein kinase PITALRE; Tat-associated kinase complex catalytic subunit	WB, IHC-P, ICC/IF, ELISA	Human
	CDK9 Antibody (YA4790) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to CDK9.

HY-P810644

	Phospho-CDK1/2/3 (Thr14) Antibody (YA9906) CDK1; CDC2; CDC28A; CDKN1; P34CDC2; Cyclin-dependent kinase 1; CDK1; Cell division control protein 2 homolog; Cell division protein kinase 1; p34 protein kinase	WB, IHC-P	Human, Mouse, Rat
	Phospho-CDK/2/3 (Thr14) Antibody (YA9906) is a Rabbit-derived and non-conjugated IgG Recombinant, Monoclonal antibody, targeting to Phospho-Cdk1/2/3 (Thr14).

HY-P86471

	CDK4 Antibody (YA6163) CDK4; Cyclin-dependent kinase 4; Cell division protein kinase 4; PSK-J3	WB, IHC-P, ICC/IF, IP, ELISA	Human, Mouse, Rat
	CDK4 Antibody (YA6163) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CDK4.

HY-P86594

	CDK6 Antibody (YA6286) Cyclin-dependent kinase 6; Cell division protein kinase 6; Serine/threonine-protein kinase PLSTIRE;	WB, IHC-P, ICC/IF, IP, ELISA	Human
	CDK6 Antibody (YA6286) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CDK6.

HY-P83028

	CDC123 Antibody (YA2773) C10orf7; CDC123; Cell division cycle 123; D123; HT 1080; PZ32	WB, IP, FC	Human, Mouse, Rat
	CDC123 Antibody (YA2773) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CDC123.

HY-P81407

	CDC7 Antibody (YA1152) CDC7 ; CDC7L1; Cell division cycle 7-related protein kinase; CDC7-related kinase; HsCdc7; huCdc7	IHC-P	Human
	CDC7 Antibody (YA1152) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CDC7.

HY-P86535

	CDK2 Antibody (YA6227) CDK2; CDKN2; Cyclin-dependent kinase 2; Cell division protein kinase 2; p33 protein kinase	WB, IHC-P, ICC/IF, IP, ELISA	Human, Mouse, Rat
	CDK2 Antibody (YA6227) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CDK2.

HY-P81455

	HRPT2/Parafibromin Antibody (YA1200) CDC73; C1orf28, HRPT2; Parafibromin; Cell division cycle protein 73 homolog; Hyperparathyroidism 2 protein	IHC-P	Human
	HRPT2/Parafibromin Antibody (YA1200) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to HRPT2/Parafibromin.

HY-P81407A

	CDC7 Antibody (YA1152)(PBS only) CDC7 ; CDC7L1; Cell division cycle 7-related protein kinase; CDC7-related kinase; HsCdc7; huCdc7	IHC-P	Human
	CDC7 Antibody (YA1152) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CDC7.

HY-P80798

	Phospho-CDK2 (Tyr15) Antibody (YA217) 1 Publications Verification CDK2; CDKN2; Cyclin-dependent kinase 2; Cell division protein kinase 2; p33 protein kinase	WB, IP	Human, Hamster, Rat
	Phospho-CDK2 (Tyr15) Antibody (YA217) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Phospho-CDK2 (Tyr15).

HY-P810606

	Phospho-Cdk2 (Tyr15) Antibody (YA9868) CDK2; CDKN2; Cyclin-dependent kinase 2; Cell division protein kinase 2; p33 protein kinase	WB, IHC-P, IP, IF-Tissue	Human, Mouse, Rat
	Phospho-Cdk2 (Tyr15) Antibody (YA9868) is a Rabbit-derived and non-conjugated IgG Recombinant, Monoclonal antibody, targeting to Phospho-Cdk2 (Tyr15).

HY-P81455A

	HRPT2/Parafibromin Antibody (YA1200)(PBS only) CDC73; C1orf28, HRPT2; Parafibromin; Cell division cycle protein 73 homolog; Hyperparathyroidism 2 protein	IHC-P	Human
	HRPT2/Parafibromin Antibody (YA1200) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to HRPT2/Parafibromin.

HY-P80798A

	Phospho-CDK2 (Tyr15) Antibody (YA217)(PBS only) CDK2; CDKN2; Cyclin-dependent kinase 2; Cell division protein kinase 2; p33 protein kinase	WB, IP	Human, Hamster, Rat
	Phospho-CDK2 (Tyr15) Antibody (YA217) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Phospho-CDK2 (Tyr15).

HY-P85531

	CDK4 Antibody (YA5223) Cdk 4; cdk4; CDK4 protein; CDK4_HUMAN; Cell division kinase 4; Cell division protein kinase 4; CMM 3; CMM3; Crk3; Cyclin dependent kinase 4; Cyclin-dependent kinase 4; Melanoma cutaneous malignant 3; MGC14458; p34 cdk4; PSK J3; PSK-J3.	WB	Human, Mouse, Rat
	CDK4 Antibody (YA5223) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to CDK4.

HY-P83423

	CDC40 Antibody (YA3168) cell division cycle 40; EH-binding protein 3; EHB3; pre-mRNA splicing factor 17; PRP17; PRPF17; Cdc40	WB, IHC-P, ICC/IF, FC	Human, Mouse, Rat
	CDC40 Antibody (YA3168) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CDC40.

HY-P85693

	CDK5 Antibody (YA5385) Cyclin-dependent kinase 5; Cell division protein kinase 5; Serine/threonine-protein kinase PSSALRE; Tau protein kinase II catalytic subunit; TPKII catalytic subunit;	IHC-P, WB	Human, Mouse, Rat
	CDK5 Antibody (YA5385) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to CDK5.

HY-P82881

	CDC6 Antibody (YA2626) CDC6; CDC18L; Cell division control protein 6 homolog; CDC6-related protein; Cdc18-related protein; HsCdc18; p62(cdc6); HsCDC6	WB, IHC-P, ICC/IF	Human
	CDC6 Antibody (YA2626) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CDC6.

HY-P82881A

	CDC6 Antibody (YA2626)(PBS only) CDC6; CDC18L; Cell division control protein 6 homolog; CDC6-related protein; Cdc18-related protein; HsCdc18; p62(cdc6); HsCDC6	WB, IHC-P, ICC/IF	Human
	CDC6 Antibody (YA2626)(PBS only) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CDC6.

HY-P810605

	Phospho-CDK1 (Thr161) + CDK2/CDK3 (Thr160) Antibody (YA9867) CDK2; CDKN2; Cyclin-dependent kinase 2; Cell division protein kinase 2; p33 protein kinase	WB, Dot Blot	Human
	Phospho-CDK1 (Thr161) + CDK2/CDK3 (Thr160) Antibody (YA9867) is a Rabbit-derived and non-conjugated IgG Recombinant, Monoclonal antibody, targeting to Phospho-CDK1 (Thr161) + CDK2/CDK3 (Thr160).

HY-P810395

	MCM4 Antibody (YA9712) 19G, AI325074, AU045576, CDC 21, CDC 54, CDC21, CDC21 homolog, CDC21, S. pombe, homolog of, CDC54, Cell division cycle 21, S. pombe, homolog of	WB, IHC-P	Human
	MCM4 Antibody (YA9712) is a Rabbit-derived and non-conjugated IgG Recombinant,Monoclonal antibody, targeting to MCM4.

HY-P81295A

	Phospho-CDC6 (Ser54) Antibody (YA1017) CDC6; CDC18L; Cell division control protein 6 homolog; CDC6-related protein; Cdc18-related protein; HsCdc18; p62(cdc6); HsCDC6	WB, ICC/IF	Human
	Phospho-CDC6 (Ser54) Antibody (YA1017) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Phospho-CDC6 (Ser54).

HY-P83431

	CDCA3 Antibody (YA3176) Cell division cycle-associated protein 3; Trigger of mitotic entry protein 1; TOME-1; Gene-rich cluster protein C8; CDCA3; C8; GRCC8; TOME1	WB, ICC/IF	Human, Mouse, Rat
	CDCA3 Antibody (YA3176) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CDCA3.

HY-P81295

	Phospho-CDC6 (Ser106) Antibody (YA1016) CDC6; CDC18L; Cell division control protein 6 homolog; CDC6-related protein; Cdc18-related protein; HsCdc18; p62(cdc6); HsCDC6	WB	Human, Rat
	Phospho-CDC6 (Ser106) Antibody (YA1016) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Phospho-CDC6 (Ser106).

HY-P81295B

	Phospho-CDC6 (Ser54) Antibody (YA1017)(PBS only) CDC6; CDC18L; Cell division control protein 6 homolog; CDC6-related protein; Cdc18-related protein; HsCdc18; p62(cdc6); HsCDC6	WB, ICC/IF	Human
	Phospho-CDC6 (Ser54) Antibody (YA1017)(PBS only) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Phospho-CDC6 (Ser54).

HY-P85097

	Cdc27 Antibody (YA4789) CDC27; ANAPC3; D0S1430E; D17S978E; Cell division cycle protein 27 homolog; Anaphase-promoting complex subunit 3; APC3; CDC27 homolog; CDC27Hs; H-NUC	WB, IHC-P, ICC/IF, FC	Human
	Cdc27 Antibody (YA4789) is a Rabbit-derived and non-conjugated monoclonal antibody, targeting to Cdc27.

HY-P80613

	CDK5 Antibody (YA796) Cdk 5; Cdk5; CDK5_HUMAN; Cell division protein kinase 5; Crk6; Cyclin dependent kinase 5; Cyclin-dependent kinase 5; Protein kinase CDK5 splicing; PSSALRE; Serine threonine protein kinase PSSALRE; Serine/threonine-protein kinase PSSALRE; Tau protein kinas	WB, ICC/IF	Human, Mouse, Rat, Monkey
	CDK5 Antibody (YA796) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CDK5.

HY-P85533

	CDK5(N-term) Antibody (YA5225) Cdk 5; Cdk5; CDK5_HUMAN; Cell division protein kinase 5; Crk6; Cyclin dependent kinase 5; Cyclin-dependent kinase 5; Protein kinase CDK5 splicing; PSSALRE; Serine threonine protein kinase PSSALRE; Serine/threonine-protein kinase PSSALRE; Tau protein kinase II catalytic subunit; TPKII catalytic subunit.	WB, ICC/IF	Human, Mouse, Rat, Monkey
	CDK5(N-term) Antibody (YA5225) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to CDK5(N-term).

HY-P80389

	Cdk7 Antibody (YA3495) CDK7_HUMAN; Cyclin-dependent kinase 7; EC:2.7.11.22; EC:2.7.11.23; CDK7; CAK; CAK1; CDKN7; MO15; STK1; 39 kDa protein kinase (p39 Mo15); CDK-activating kinase 1; Cell division protein kinase 7; Serine/threonine-protein kinase 1; TFIIH basal transcription factor complex kinase subunit;	WB	Human
	Cdk7 Antibody (YA3495) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Cdk7.

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Cat. No.	Product Name		Classification

HY-16062

ARQ 621		Alkynes
ARQ 621 is an allosteric, potent and selective inhibitor of Eg5, a microtubule-based ATPase motor protein involved in cell division. Anti-tumor activity . ARQ 621 is a kinesin inhibitor . ARQ 621 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Cat. No.	Product Name		Classification

HY-17563

2'-Deoxyguanosine 5+ Cited Publications Deoxyguanosine; Guanine deoxyriboside		Nucleoside Analogs Guanosine
2’-Deoxyguanosine (Deoxyguanosine) is a purine nucleoside with a variety of biological activities. 2’-Deoxyguanosine can induce DNA division in mouse thymus cells. 2’-Deoxyguanosine is a potent cell division inhibitor in plant cells .

HY-W010800

Cholesteryl hemisuccinate		Cholesterol
Cholesteryl hemisuccinate is a with hepatoprotective an anticancer activity. Cholesteryl hemisuccinate inhibits Acetaminophen (AAP, HY-66005) hepatotoxicity, and prevents AAP-induced hepatic apoptosis and necrosis. Cholesteryl hemisuccinate inhibits DNA polymerase and DNA topoisomerase to inhibit DNA replication and repair and cell division. Thus, Cholesteryl hemisuccinate inhibits tumor growth .

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cell+division

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