Boerelasin E
Boerelasin E is the first cytochalasan possessing a cis-configured Δ21(22) double bond that can be isolated from endophytic fungus Boeremia exigua. Boerelasin E exhibits antiproliferative activity against MCF-7 cells (IC50=20.52 μM) more potent than cisplatin (HY-17394). Boerelasin E inhibits the complete cell division of MCF-7 cells by arresting them in the G2/M phase and inducing apoptosis[1].
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- Formel: C29H35NO5
- Molecular Weight:477.59
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
Chemical Information
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Molecular Weight 477.59
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Formel C29H35NO5
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SMILES
C=C1[C@@H](O)[C@@](/C=C/C[C@H](C)CCCC(/C=C\2)=O)([H])[C@]([C@@]3([H])[C@@H]1C)(OC2=O)C(N[C@H]3CC4=CC=CC=C4)=O
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Structure Classification
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Initial Source
Boeremia exigua
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)