6-Benzylaminopurine
Based on 4 publication(s) in Google Scholar
6-Benzylaminopurine (Benzyladenine) is a cytokinin that causes plant growth and development by stimulating cell division and inhibiting respiratory kinases, thereby prolonging the preservation of green vegetables.
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- Pureza: 99.97%
- No. CAS: 1214-39-7
- Fòrmula: C12H11N5
- Peso molecular:225.25
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Almacenamiento:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
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Actividad biológica
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Chemical Information
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Solvente y solubilidad
- Pureza y Documentación
- Referencias
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Publications Citing Use of MedChemExpress (MCE) 6-Benzylaminopurine
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Actividad biológica
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Cytokinin |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HL-60 | IC50 |
>100 μM
Compound: BAP, benzylaminopurine
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Antiproliferative activity against human HL60 cells
Antiproliferative activity against human HL60 cells
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[PMID: 17300934] |
| Oocyte | IC50 |
200 μM
Compound: 9
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Inhibitory activity against purified cdc2 p34/Cyclin B obtained from M phase oocytes of the starfish Marthasterias glacialis.
Inhibitory activity against purified cdc2 p34/Cyclin B obtained from M phase oocytes of the starfish Marthasterias glacialis.
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[PMID: 9046330] |
| RD | CC50 |
547 μM
Compound: 35
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Cytotoxicity against human RD cells
Cytotoxicity against human RD cells
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[PMID: 26854380] |
| RD | EC50 |
0.42 μM
Compound: 35
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Antiviral activity against Enterovirus 71 infected in human RD cells assessed as cell viability after 3 days by MTS assay
Antiviral activity against Enterovirus 71 infected in human RD cells assessed as cell viability after 3 days by MTS assay
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[PMID: 26854380] |
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 1214-39-7
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Appearance Solid
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Peso molecular 225.25
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Fòrmula C12H11N5
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Color White to off-white
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SMILES
C12=NC=NC(NCC3=CC=CC=C3)=C1NC=N2
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Synonyms
Benzyladenine; 6-BAP; N6-Benzyladenine
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Initial Source
Apis cerana
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year
Publications (4)
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Journal Impact Factor
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Most Recent
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Autophagy
The Valsa mali effector Vm1G-1794 protects the aggregated MdEF-Tu from autophagic degradation to promote infection in apple. [Abstract]2023 Jun;19(6):1745-1763. PMID: 36449354 -
Nat Commun
2025 Apr 11;16(1):3475. PMID: 40216803 -
Nat Plants
2024 Jan;10(1):180-191. PMID: 38172575 -
Plant Physiol
HECATE2 acts with GLABROUS3 and Tu to boost cytokinin biosynthesis and regulate cucumber fruit wart formation. [Abstract]2021 Nov 3;187(3):1619-1635. PMID: 34618075
Solvente y solubilidad
DMSO : 50 mg/mL (221.98 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 2.5 mg/mL (11.10 mM); Clear solution
This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: ≥ 2.5 mg/mL (11.10 mM); Clear solution
This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
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%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
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%+
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+%Tween-80 + +
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%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL.
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Pureza y Documentación
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Ficha de datos (275 KB)
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SDS (701 KB)
- English - EN (701 KB)
- Français - FR (701 KB)
- Deutsch - DE (701 KB)
- Norwegian - NO (701 KB)
- Español - ES (701 KB)
- Swedish - SV (701 KB)
- Italian - IT (701 KB)
- Korean - KR (701 KB)
- Portuguese - PT (701 KB)
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Instrucciones de manejo (2659 KB)
Referencias
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.4395 mL | 22.1976 mL | 44.3951 mL | 110.9878 mL |
| 5 mM | 0.8879 mL | 4.4395 mL | 8.8790 mL | 22.1976 mL | |
| 10 mM | 0.4440 mL | 2.2198 mL | 4.4395 mL | 11.0988 mL | |
| 15 mM | 0.2960 mL | 1.4798 mL | 2.9597 mL | 7.3992 mL | |
| 20 mM | 0.2220 mL | 1.1099 mL | 2.2198 mL | 5.5494 mL | |
| 25 mM | 0.1776 mL | 0.8879 mL | 1.7758 mL | 4.4395 mL | |
| 30 mM | 0.1480 mL | 0.7399 mL | 1.4798 mL | 3.6996 mL | |
| 40 mM | 0.1110 mL | 0.5549 mL | 1.1099 mL | 2.7747 mL | |
| 50 mM | 0.0888 mL | 0.4440 mL | 0.8879 mL | 2.2198 mL | |
| 60 mM | 0.0740 mL | 0.3700 mL | 0.7399 mL | 1.8498 mL | |
| 80 mM | 0.0555 mL | 0.2775 mL | 0.5549 mL | 1.3873 mL | |
| 100 mM | 0.0444 mL | 0.2220 mL | 0.4440 mL | 1.1099 mL |
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