1. Alkaloids
  2. 6-(γ,γ-Dimethylallylamino)purine

6-(γ,γ-Dimethylallylamino)purine (Synonyms: N6-(2-lsopentenyl)adenine)

Cat. No.: HY-112103 Purity: 99.79%
Handling Instructions

6-(γ,γ-Dimethylallylamino)purine is a plant growth substance.

For research use only. We do not sell to patients.

6-(γ,γ-Dimethylallylamino)purine Chemical Structure

6-(γ,γ-Dimethylallylamino)purine Chemical Structure

CAS No. : 2365-40-4

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Based on 1 publication(s) in Google Scholar

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Description

6-(γ,γ-Dimethylallylamino)purine is a plant growth substance.

In Vitro

Derivative UV spectroscopic data show that the plant growth substances 6-(γ,γ-Dimethylallylamino)purine (N6-(delta 2-isopentenyl) adenine, i6Ade)and indolylacetic acid (IAA) can bind to the yeast alcohol dehydrogenase (ADH) and affect coenzyme-enzyme binding. At fixed ethanol concentrations (27.8 and 111.1 mM) and varying NAD+ concentrations (0.033-2 mM), as well as at fixed levels of coenzyme (0.67 and 2 mM), and at varying concentrations of ethanol (1.4-111.1 mM), the rate of ethanol oxidation is significantly inhibited by i6Ade and IAA. The kinetics of the ADH reaction is affected by two inhibition constants (Ki and Ki') which correspond to the dissociation constants of complexes EI and ESI, respectively. For i6Ade the Ki=0.52±0.06 mM and Ki'=0.74±0.07 mM, and for IAA the Ki=0.88±0.03 mM and Ki'=0.99±0.02 mM[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

203.24

Formula

C₁₀H₁₃N₅

CAS No.
SMILES

C/C(C)=C/CNC1=C2N=CNC2=NC=N1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 60 mg/mL (295.22 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.9203 mL 24.6015 mL 49.2029 mL
5 mM 0.9841 mL 4.9203 mL 9.8406 mL
10 mM 0.4920 mL 2.4601 mL 4.9203 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.5 mg/mL (12.30 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (12.30 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.5 mg/mL (12.30 mM); Clear solution

*All of the co-solvents are provided by MCE.
References
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Keywords:

6-(γ,γ-Dimethylallylamino)purineN6-(2-lsopentenyl)adenineOthersInhibitorinhibitorinhibit

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Product Name:
6-(γ,γ-Dimethylallylamino)purine
Cat. No.:
HY-112103
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