1. Metabolic Enzyme/Protease Cell Cycle/DNA Damage Anti-infection
  2. Endogenous Metabolite DNA/RNA Synthesis Bacterial
  3. DL-Glutamic acid

DL-Glutamic acid is a racemic amino acid mixture and an antibacterial agent. DL-Glutamic acid reduces RNA and DNA levels, with a more significant effect on RNA. DL-Glutamic acid inhibits cell division of Rhodospirillum rubrum.

For research use only. We do not sell to patients.

DL-Glutamic acid

DL-Glutamic acid Chemical Structure

CAS No. : 617-65-2

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Based on 1 publication(s) in Google Scholar

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Description

DL-Glutamic acid is a racemic amino acid mixture and an antibacterial agent. DL-Glutamic acid reduces RNA and DNA levels, with a more significant effect on RNA. DL-Glutamic acid inhibits cell division of Rhodospirillum rubrum[1].

In Vitro

DL-Glutamic acid (0.01 M; until middle lag phase) inhibits cell division but not elongation of Rhodospirillum rubrum during initial growth, while concentrations below 0.0025 M do not induce this effect, and cells regain normal morphology after a lag phase[1].
DL-Glutamic acid (0.012 M; up to 300 h) reduces cellular ribonucleic acid (RNA) and deoxyribonucleic acid (DNA) levels in growing Rhodospirillum rubrum, with RNA affected more severely than DNA, and nucleic acid synthesis ceases before dry weight growth stops[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

147.13

Formula

C5H9NO4

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

NC(CCC(O)=O)C(O)=O

Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 1 mg/mL (6.80 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 6.7967 mL 33.9836 mL 67.9671 mL
5 mM 1.3593 mL 6.7967 mL 13.5934 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: ≥97.0%

References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 6.7967 mL 33.9836 mL 67.9671 mL 169.9178 mL
5 mM 1.3593 mL 6.7967 mL 13.5934 mL 33.9836 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
DL-Glutamic acid
Cat. No.:
HY-W041895
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