DL-Glutamic acid-d₅

Name: DL-Glutamic acid-d 5
Brand: MedChemExpress
SKU: HY-W041895S
Rating: 4.5 (1 reviews)

Cat. No.: HY-W041895S Purity: 99.68%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

DL-Glutamic acid-d₅ is the deuterium labeled DL-Glutamic acid. DL-Glutamic acid is the conjugate acid of Glutamic acid, which acts as a fundamental metabolite. Comparing with the second phase of polymorphs α and β L-Glutamic acid, DL-Glutamic acid presents better stability[1].

For research use only. We do not sell to patients.

DL-Glutamic acid-d<sub>5</sub> Chemical Structure

DL-Glutamic acid-d₅ Chemical Structure

CAS No. : 14341-79-8

Size	Price	Stock	Quantity
1 mg	USD 50	In-stock	Estimated Time of Arrival: December 31
5 mg	USD 110	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 175	In-stock	Estimated Time of Arrival: December 31
25 mg	USD 320	In-stock	Estimated Time of Arrival: December 31
50 mg		Get quote
100 mg		Get quote

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Based on 1 publication(s) in Google Scholar

Other Forms of DL-Glutamic acid-d₅:

DL-Glutamic acid In-stock

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Biological Activity
Purity & Documentation
References
Customer Review

Description

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

152.16

Formula

C₅H₄D₅NO₄

CAS No.

14341-79-8

Appearance

Solid

Color

White to off-white

SMILES

OC(C([2H])([2H])C([2H])([2H])C(N)([2H])C(O)=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

H₂O : 25 mg/mL (164.30 mM; Need ultrasonic)

DMSO : 1 mg/mL (6.57 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	6.5720 mL	32.8601 mL	65.7203 mL
5 mM	1.3144 mL	6.5720 mL	13.1441 mL
10 mM	0.6572 mL	3.2860 mL	6.5720 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
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Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: 99.68%

Select Batch:

Data Sheet (273 KB) SDS (393 KB)

COA (250 KB) HNMR (529 KB) RP-HPLC (902 KB)

Handling Instructions (2659 KB)

References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO / H₂O	1 mM	6.5720 mL	32.8601 mL	65.7203 mL	164.3007 mL
DMSO / H₂O	5 mM	1.3144 mL	6.5720 mL	13.1441 mL	32.8601 mL
H₂O	10 mM	0.6572 mL	3.2860 mL	6.5720 mL	16.4301 mL
	15 mM	0.4381 mL	2.1907 mL	4.3814 mL	10.9534 mL
	20 mM	0.3286 mL	1.6430 mL	3.2860 mL	8.2150 mL
	25 mM	0.2629 mL	1.3144 mL	2.6288 mL	6.5720 mL
	30 mM	0.2191 mL	1.0953 mL	2.1907 mL	5.4767 mL
	40 mM	0.1643 mL	0.8215 mL	1.6430 mL	4.1075 mL
	50 mM	0.1314 mL	0.6572 mL	1.3144 mL	3.2860 mL
	60 mM	0.1095 mL	0.5477 mL	1.0953 mL	2.7383 mL
	80 mM	0.0822 mL	0.4108 mL	0.8215 mL	2.0538 mL
	100 mM	0.0657 mL	0.3286 mL	0.6572 mL	1.6430 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.