2. Signaling Pathways
  3. Anti-infection
  4. VRK

VRK

Vaccinia-Related Kinases

VRKs has three members: VRK1, VRK2, VRK3. VRKs are implicated in a number of cellular processes and linked to a variety of tumors.

VRK Related Products (3):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-126542
    VRK-IN-1
    		Inhibitor 99.47%
    VRK-IN-1 is a potent and selective inhibitor of vaccinia-related kinases 1 (VRK1), with an IC50 of 150 nM. VRK1 is human Ser/Thr protein kinases associated with increased cell division and neurological disorders.
    VRK-IN-1
  • HY-158975
    VRK1/CK1-IN-1
    		Inhibitor 98.69%
    VRK1/CK1-IN-1 (compound 36) is a dual VRK1 and CK1 family inhibitor, with a Ki of 37.9 nM against human VRK1, 8.3 nM against human CK1δ, and 7.8 nM against human CK1ε. VRK1/CK1-IN-1 exhibits extremely low activity against VRK2. VRK1/CK1-IN-1 can be used in studies related to p53-deficient tumors.
    VRK1/CK1-IN-1
  • HY-N8692
    Dihydrobaicalein
    		Inhibitor 99.94%
    Dihydrobaicalein is a PLK1 Inhibitor with an IC50 of 6.3 μM. Dihydrobaicalein also inhibits VRK2 and PLK2. Dihydrobaicalein is a natural product that can be isolated from Scutellaria scandens.
    Dihydrobaicalein