1. Metabolic Enzyme/Protease
  2. Phosphatase
  3. CDC25B-IN-1

CDC25B-IN-1 

Cat. No.: HY-126246 Purity: 98.01%
Handling Instructions

CDC25B-IN-1 (compound 4a) is a potent inhibitor of cell division cycle 25B (CDC25B) phosphatase, with a Ki of 8.5 μM. CDC25B-IN-1 potently inhibits cell proliferation and colony formation, causes an increase of the G2/M phase.

For research use only. We do not sell to patients.

CDC25B-IN-1 Chemical Structure

CDC25B-IN-1 Chemical Structure

CAS No. : 2374831-10-2

Size Price Stock Quantity
10 mM * 1  mL in DMSO USD 274 In-stock
Estimated Time of Arrival: December 31
5 mg USD 350 In-stock
Estimated Time of Arrival: December 31
10 mg USD 550 In-stock
Estimated Time of Arrival: December 31
50 mg USD 1650 In-stock
Estimated Time of Arrival: December 31
100 mg USD 2250 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

Top Publications Citing Use of Products
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Description

CDC25B-IN-1 (compound 4a) is a potent inhibitor of cell division cycle 25B (CDC25B) phosphatase, with a Ki of 8.5 μM. CDC25B-IN-1 potently inhibits cell proliferation and colony formation, causes an increase of the G2/M phase[1].

IC50 & Target

Ki: 8.5 μM (CDC25B phosphatase)[1]

Molecular Weight

321.37

Formula

C₂₀H₁₉NO₃

CAS No.

2374831-10-2

SMILES

COC1=CC2=CC=CC=C2C(NC3=CC=CC(C(OCC)=O)=C3)=C1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (311.17 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.1117 mL 15.5584 mL 31.1168 mL
5 mM 0.6223 mL 3.1117 mL 6.2234 mL
10 mM 0.3112 mL 1.5558 mL 3.1117 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.5 mg/mL (7.78 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.5 mg/mL (7.78 mM); Clear solution

*All of the co-solvents are provided by MCE.
References

Purity: 98.01%

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Keywords:

CDC25B-IN-1PhosphataseInhibitorinhibitorinhibit

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Product name:
CDC25B-IN-1
Cat. No.:
HY-126246
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