2. Recombinant Proteins
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  4. Transferases (EC 2) Serine/Threonine Kinase Proteins CMGC
  5. Cyclin-Dependent Kinases (CDKs) CDK
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  7. CDK15-CCNY Heterodimer Protein, Human (sf9)

The CDK15ic protein, functioning as an antiapoptotic kinase, counteracts TRAIL/TNFSF10-induced apoptosis by phosphorylating BIRC5 at 'Thr-34'. This regulatory role crucially inhibits programmed cell death triggered by TRAIL/TNFSF10, highlighting the heterodimer's active contribution to antiapoptotic signaling. CDK15-CCNY Heterodimer Protein, Human (sf9) is a recombinant protein dimer complex containing human-derived CDK15-CCNY Heterodimer protein, expressed by sf9 insect cells , with tag free.

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제품 설명

The CDK15ic protein, functioning as an antiapoptotic kinase, counteracts TRAIL/TNFSF10-induced apoptosis by phosphorylating BIRC5 at 'Thr-34'. This regulatory role crucially inhibits programmed cell death triggered by TRAIL/TNFSF10, highlighting the heterodimer's active contribution to antiapoptotic signaling. CDK15-CCNY Heterodimer Protein, Human (sf9) is a recombinant protein dimer complex containing human-derived CDK15-CCNY Heterodimer protein, expressed by sf9 insect cells , with tag free.
Background

The CDK15ic protein operates as an antiapoptotic kinase, actively mitigating TRAIL/TNFSF10-induced apoptosis by catalyzing the phosphorylation of BIRC5 at 'Thr-34'. Through this regulatory mechanism, the heterodimeric complex plays a crucial role in countering apoptotic signaling, thereby contributing to the inhibition of programmed cell death triggered by TRAIL/TNFSF10.
Species

Human
Source

Sf9 insect cells
Tag

Tag Free
Accession

Q96Q40-1 (M1-W435)&Q8ND76-1 (M1-S341)
Gene ID

65061&219771
Synonyms
CDK15; CCNY; Cyclin-dependent kinase 15; Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 7 protein; Cell division protein kinase 15; Serine/threonine-protein kinase ALS2CR7; Serine/threonine-protein kinase PFTAIRE-2; Cyclin-Y; Cyc-Y; Cyclin box protein 1; Cyclin fold protein 1; cyclin-X
Purity

≥ 90%, as determined by reducing SDS-PAGE.
Endotoxin Level

<1 EU/μg, determined by LAL method.
각종 서류
Handling Instructions (2659 KB)

CDK15-CCNY Heterodimer Protein, Human (sf9) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

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The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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CDK15-CCNY Heterodimer Protein, Human (sf9)
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