CDK15/PFTK2
CDK15, once designated PFTK2, is the less-studied paralog of CDK14 and, like CDK14, depends on palmitoylated cyclin Y for membrane localization and activity. Its expression is enriched in brain, and it has been implicated in transcriptional regulation, in neuronal development, and in the growth of certain tumor cells, where CDK15 knockdown reduces proliferation. Because CDK14 and CDK15 share the cyclin Y partnership, isoform-selective tools are still needed to separate their biology, and CDK15-specific functions remain incompletely defined compared with the well-characterized LRP6-Wnt role of CDK14. Recombinant CDK15 in complex with cyclin Y supports enzymology and selectivity studies of this CDK subfamily.
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CDK15/PFTK2 Recombinant Proteins (2)
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Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- Formula: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
