CDC123 Antibody (YA2773)
(Synonyms: C10orf7; CDC123; Cell division cycle 123; D123; HT 1080; PZ32)CDC123 Antibody (YA2773) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CDC123.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, IP, FC
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Reactivity :
Human, Mouse, Rat
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Formulation:
Supplied in rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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IP
IP: Immunoprecipitation
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FC
FC: Flow Cytometry
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|---|---|---|---|
| Dilution Ratio | 1:500-1:1000 | 1:50 | 1:50-1:100 |
Product Details
CDC123 Antibody (YA2773) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CDC123.
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Host Rabbit
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Clonality Recombinant, Monoclonal
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Species ReactivityHuman, Mouse, Rat
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Observed Molecular WeightObserved band size: 39 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 39 kDa
Entrez Gene: 8872 Human ; 98828 Mouse ; 116656 Rat
SwissProt: O75794 Human ; Q8CII2 Mouse ; Q62834 Rat
OMIM: 617708 Human
A synthesized peptide derived from human CDC123 aa11-70/336.
Endogenous
Affinity Purified
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Liquid
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Formulation
Supplied in rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
CDC123 is an ATP-dependent protein-folding chaperone for the eIF2 complex. Binds to the gamma subunit of the eIF2 complex which allows the subunit to assemble with the alpha and beta subunits[1][2].
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Subcellular Localization
Cytoplasm
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Expression
Tissue_specificity:It is widely expressed in the spleen, thymus, prostate, testes, ovaries, small intestine, colon, and leukocytes, with the highest expression in the testes. -
Subunit
Interacts with the eIF2 complex gamma subunit EIF2S3 (via C-terminus); the interaction is direct (PubMed:35031321, PubMed:37507029). Interacts with the eIF2 complex alpha subunit EIF2S1 (PubMed:31836389, PubMed:35031321). Interacts with the eIF2 complex beta subunit EIF2S2 (PubMed:31836389, PubMed:35031321)
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SwissProt ID
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Synonyms
C10orf7; CDC123; Cell division cycle 123; D123; HT 1080; PZ32
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Research Field
Cell Biology
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