N-Deacetyl-N-formylcolchicine

(Synonyms: N-Formyl-N-deacetylcolchicine)
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N-Deacetyl-N-formylcolchicine (N-Formyl-N-deacetylcolchicine, Compound 11) is a selective inhibitor targeting the colchicine-binding site of tubulin. N-Deacetyl-N-formylcolchicine shows antiproliferative activity against various cancer cell lines with IC50 values of 32.61-100.28 nM. N-Deacetyl-N-formylcolchicine inhibits microtubule polymerization to block cell division, induces cancer cell apoptosis and suppresses migration. N-Deacetyl-N-formylcolchicine is promising for research of cancers such as lung cancer and various solid tumors.

For research use only. We do not sell to patients.

  • CAS No.: 7411-12-3
  • Formula: C21H23NO6
  • Molecular Weight:385.41
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

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100 mg

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