N-Deacetyl-N-formylcolchicine
Based on 1 Customer Validation
N-Deacetyl-N-formylcolchicine (N-Formyl-N-deacetylcolchicine, Compound 11) is a selective inhibitor targeting the colchicine-binding site of tubulin. N-Deacetyl-N-formylcolchicine shows antiproliferative activity against various cancer cell lines with IC50 values of 32.61-100.28 nM. N-Deacetyl-N-formylcolchicine inhibits microtubule polymerization to block cell division, induces cancer cell apoptosis and suppresses migration. N-Deacetyl-N-formylcolchicine is promising for research of cancers such as lung cancer and various solid tumors.
For research use only. We do not sell to patients.
- CAS No.: 7411-12-3
- Formula: C21H23NO6
- Molecular Weight:385.41
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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CAS No. 7411-12-3
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Molecular Weight 385.41
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Formula C21H23NO6
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SMILES
COC1=C2C(C([C@H](CCC2=CC(OC)=C1OC)NC=O)=C3)=CC=C(OC)C3=O
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Synonyms
N-Formyl-N-deacetylcolchicine
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)