CDC123 Antibody (YA4650)(PBS only)
(Synonyms: C10orf7 antibody; CD123_HUMAN antibody; CDC123 antibody; Cell division cycle 123 antibody; Cell division cycle 123 homolog antibody; Cell division cycle protein 123 homolog antibody; D123 antibody; HT 1080 antibody; HT-1080 antibody; Protein D123 antibody; PZ32 antibody; )CDC123 Antibody (YA4650) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CDC123.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, FC
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Reactivity :
Human, Mouse, Rat
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Formulation:
Supplied in PBS, pH 7.4.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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FC
FC: Flow Cytometry
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|---|---|---|
| Dilution Ratio | 1:1000-1:5000 | 1:10-1:100 |
Product Details
CDC123 Antibody (YA4650) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CDC123.
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Host Rabbit
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Species ReactivityHuman, Mouse, Rat
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Observed Molecular WeightObserved band size: 39 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 39 kDa
A synthetic peptide of human CDC123
affinity purified.
Non-conjugated
IgG
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS, pH 7.4.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
CDC123 is an ATP-dependent protein-folding chaperone for the eIF2 complex. Binds to the gamma subunit of the eIF2 complex which allows the subunit to assemble with the alpha and beta subunits[1][2].
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Subcellular Localization
Cytoplasm
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Expression
Tissue_Specificity: Widely expressed. Expressed in spleen, thymus, prostate, testis, ovary, small intestine, colon and leukocytes with the highest expression in testis -
Isoforms & Post-Translational Modification
O75794: 336 amino acids, molecular weight 39135 Da.
Phosphorylated by a subset of GPR84-activating ligands -
Subunit
Interacts with the eIF2 complex gamma subunit EIF2S3 (via C-terminus); the interaction is direct (PubMed:35031321, PubMed:37507029)
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SwissProt ID
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Synonyms
C10orf7 antibody; CD123_HUMAN antibody; CDC123 antibody; Cell division cycle 123 antibody; Cell division cycle 123 homolog antibody; Cell division cycle protein 123 homolog antibody; D123 antibody; HT 1080 antibody; HT-1080 antibody; Protein D123 antibody; PZ32 antibody;
Documentation
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