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Results for "

4-hydrox

" in MedChemExpress (MCE) Product Catalog:

標的別:	17β-HSD (1) 5-HT Receptor (3) Acyltransferase (2) ADC Linker (3) Adrenergic Receptor (12) Akt (8) Aldehyde Dehydrogenase (ALDH) (4) Aldose Reductase (1) Amino Acid Derivatives (2) Amyloid-β (1) Antibiotic (5) Apoptosis (23) Autophagy (7) Bacterial (48) Bcl-2 Family (2) Biochemical Assay Reagents (32) Carnitine Palmitoyltransferase (CPT) (1) Caspase (1) Cholinesterase (ChE) (2) Constitutive Androstane Receptor (1) COX (9) Cytochrome P450 (4) DNA/RNA Synthesis (4) Dopamine β-hydroxylase (1) Drug Derivative (11) Drug Intermediate (16) Drug Metabolite (50) Endogenous Metabolite (70) Environmental Pollutants (6) ERK (1) Estrogen Receptor/ERR (18) Fatty Acid Synthase (FASN) (1) Ferroptosis (4) Free Fatty Acid Receptor (3) Fungal (13) GABA Receptor (2) HBV (3) Histone Acetyltransferase (8) HMG-CoA Reductase (HMGCR) (1) IKK (1) Insecticide (2) Interleukin Related (1) Isotope-Labeled Compounds (86) JNK (6) Keap1-Nrf2 (7) MDM-2/p53 (4) MOFs (8) Monoamine Oxidase (1) Myosin (2) NF-κB (2) Nucleoside Antimetabolite/Analog (3) OAT (1) Oxidative Phosphorylation (2) p38 MAPK (3) Parasite (6) PDI (3) PI3K (7) Potassium Channel (3) PPAR (2) PROTAC Linkers (17) Proteasome (2) Proton Pump (1) Quinone Reductase (1) RAR/RXR (1) Reactive Oxygen Species (ROS) (11) Reference Standards (62) ROR (1) Serotonin Transporter (1) Sirtuin (3) SOD (1) Sodium Channel (6) TNF Receptor (1) Tyrosinase (2) UGT (1) Virus Protease (1)
研究分野別:	Cancer (73) Cardiovascular Disease (22) Endocrinology (6) Infection (58) Inflammation/Immunology (51) Metabolic Disease (54) Neurological Disease (45)
クリックケミストリー:	Alkynes (1)
Oligonucleotides:	Preservatives (1) Sweetening Agents (1)

390

阻害剤およびアゴニスト

生化学アッセイ試薬

ペプチド

116

天然物

組換えタンパク質

105

同位体標識化合物

抗体

クリックケミストリー

オリゴヌクレオチド

製品番号	製品名	Target	研究分野	構造式

HY-Y0264

4-Hydroxybenzoic acid	Endogenous Metabolite Bacterial	Infection
4-Hydroxybenzoic acid, a phenolic derivative of benzoic acid, could inhibit most gram-positive and some gram-negative bacteria, with an IC₅₀ of 160 μg/mL.

HY-W008772

4-Hydroxymephenytoin	Drug Metabolite	Others
4-Hydroxymephenytoin is a metabolism of an antiepileptic agent mephenytoin, which is used as a CYP2C19 substrate.

HY-N7204

4-Hydroxyderricin 1 Publications Verification	Monoamine Oxidase Dopamine β-hydroxylase Apoptosis	Neurological Disease Inflammation/Immunology
4-Hydroxyderricin, the major active ingredients of Angelica keiskei Koidzumi, is an orally active, potent selective MAO-B (Monoamine oxidase inhibitors) inhibitor with an IC₅₀ of 3.43 μM. 4-Hydroxyderricin also mildly inhibits dopamine β (DBH)-hydroxylase activity. 4-Hydroxyderricin has antidepressant activity, anti-allergic, anti-diabetic, anti-oxidant, and antitumor effects. 4-Hydroxyderricin promotes apoptosis and cell cycle arrest through regulating PI3K/AKT/mTOR pathway in hepatocellular cells. 4-Hydroxyderricin inhibits osteoclast formation and accelerates osteoblast differentiation . 4-Hydroxyderricin is promising for research of inflammatory diseases .

HY-Y0073

4-Hydroxyacetophenone 1 Publications Verification P-hydroxyacetophenone	HBV Myosin	Infection Inflammation/Immunology Cancer
4-Hydroxyacetophenone (P-hydroxyacetophenone) is a major hepatoprotective and choleretic compound found in Artemisia and Illicium plants, exhibiting antiviral and anti-inflammatory effects against hepatitis B virus. Additionally, 4-Hydroxyacetophenone inhibits cancer cell adhesion, invasion, and migration by remodeling actin. 4-Hydroxyacetophenone holds promise for research in the fields of inflammatory diseases and cancer .

HY-107818

4-Hydroxychalcone 2 Publications Verification	ERK Akt	Cardiovascular Disease Inflammation/Immunology Endocrinology
4-Hydroxychalcone is an orally active flavonoid precursor. 4-Hydroxychalcone inhibits VEGF- and bFGF-induced phosphorylation of ERK1/2 and Akt. 4-Hydroxychalcone suppresses resistant hypertension by alleviating hyperaldosteronism, inflammation and renal injury in cryptochrome gene knockout mice. 4-Hydroxychalcone possesses anti-angiogenic activity .\n

HY-Y0892

4-Hydroxybenzyl alcohol 1 Publications Verification	Apoptosis Endogenous Metabolite	Neurological Disease Inflammation/Immunology Cancer
4-Hydroxybenzyl alcohol is a phenolic compound widely distributed in various kinds of plants. Anti-inflammatory, anti-oxidant, anti-nociceptive activity. Neuroprotective effect. Inhibitor of tumor angiogenesis and growth .

HY-34596

4-Hydroxyindole	Biochemical Assay Reagents Amyloid-β	Neurological Disease Metabolic Disease
4-Hydroxyindole is a type of hydroxyindole in which the 1H-indole at position 4 is substituted by a hydroxyl group. 4-Hydroxyindole serves as an important raw material or intermediate in the synthesis of pharmaceutical products and industrial polymers. 4-Hydroxyindole inhibits amyloid fibrillization and induces liver function impairment, thyroid abnormalities, and blood glucose fluctuations in mice. 4-Hydroxyindole holds potential for research in neurodegenerative diseases and metabolic disorders .

HY-N6856

4-Hydroxycoumarin	Bacterial Endogenous Metabolite	Infection Cancer
4-Hydroxycoumarin is an orally active coumarin derivative, one of the most versatile heterocyclic scaffolds, often used in the synthesis of various organic compounds. 4-Hydroxycoumarin possesses both electrophilic and nucleophilic properties. 4-Hydroxycoumarin is an HIV protease inhibitor and tyrosine kinase inhibitor. 4-Hydroxycoumarin has anti-inflammatory, antibacterial and anti-tumor effects .

HY-12767

Carvedilol metabolite 4-Hydroxyphenyl Carvedilol 4-hydroxyphenyl Carvedilol; 4-hydroxycarvedilol	Drug Metabolite Cytochrome P450	Metabolic Disease
4-Hydroxyphenyl Carvedilol, a metabolite of Carvedilol, is an active metabolite of Carvedilol (HY-B0006) and is produced via CYP2D6-mediated oxidation .

HY-N6858

4-Hydroxyisoleucine 4-hydroxy-L-isoleucine	Others	Metabolic Disease
4-Hydroxyisoleucine is an orally active amino acid that can be isolated from fenugreek seeds. 4-Hydroxyisoleucine displays insulinotropic and antidiabetic properties .

HY-100634

4-Hydroxypropranolol hydrochloride (±)-4-hydroxy Propranolol hydrochloride	Adrenergic Receptor	Cardiovascular Disease
4-Hydroxypropranolol hydrochloride is a non-cardiac selective β-adrenergic receptor antagonist and a metabolite produced after oral administration of Propranolol (HY-B0573B). 4-Hydroxypropranolol hydrochloride also acts as a membrane stabilizer and possesses intrinsic sympathomimetic inhibitory activity. 4-Hydroxypropranolol hydrochloride blocks β-adrenergic receptors to antagonize the effects of catecholamines, acts as a partial β-adrenergic receptor agonist, and induces membrane stabilization. 4-Hydroxypropranolol hydrochloride alters heart rate, left ventricular contractility, and atrioventricular conduction time. 4-Hydroxypropranolol hydrochloride can be used in research related to cardiovascular and cerebrovascular diseases .

HY-125904

4-Hydroxyretinoic acid 1 Publications Verification	RAR/RXR UGT Cytochrome P450 Apoptosis Drug Derivative	Neurological Disease Inflammation/Immunology Cancer
4-Hydroxyretinoic acid (4-HRA) is a derivative of Retinoic acid (HY-14649). 4-Hydroxyretinoic acid is formed via the catalysis of retinol by cytochrome P-450 isoenzymes. 4-Hydroxyretinoic acid also serves as a substrate for UDP-glucuronosyltransferase (s) and recombinant UGT2B7. 4-Hydroxyretinoic acid binds to the nuclear receptor RAR (Retinoic Acid Receptor), activates RAR and RXR-alpha, subsequently regulates gene expression and cell differentiation, and induces cancer cell apoptosis (Apoptosis). 4-Hydroxyretinoic acid also participates in multiple physiological processes such as immunoregulation, neuroprotection and antioxidation .

HY-N2208

4-Hydroxylonchocarpin 2 Publications Verification	p38 MAPK Apoptosis Reactive Oxygen Species (ROS)	Infection Metabolic Disease Inflammation/Immunology Cancer
4-Hydroxylonchocarpin is a chalcone compound. 4-Hydroxylonchocarpin enhances the phosphorylation of p38 MAPK, JNK and ERK. 4-Hydroxylonchocarpin induces reactive oxygen species (ROS) and apoptosis in liver cancer cells. 4-Hydroxylonchocarpin has various pharmacological activities, including antibacterial, anticancer, anti-retroviral, anti-tuberculosis, anti-malarial and anti-inflammatory activities .

HY-100641

4-Hydroxytolbutamide hydroxytolbutamide	Potassium Channel Autophagy	Metabolic Disease Cancer
4-Hydroxytolbutamide (Hydroxytolbutamide) is a metabolite of Tolbutamide. 4-Hydroxytolbutamide is metabolized by CYP2C8 and CYP2C9. Tolbutamide is a first generation potassium channel blocker and a sulfonylurea oral antidiabetic .

HY-115354

4-Hydroxy alprazolam	Drug Metabolite	Neurological Disease
4-Hydroxy alprazolam is a metabolite of Alprazolam. Alprazolam is metabolized primarily by hepatic microsomal oxidation, yielding 4-Hydroxy alprazolam .

HY-113158

4-Hydroxyhippuric acid	Drug Metabolite	Metabolic Disease
4-Hydroxyhippuric acid is a metabolite of polyphenols. 4-Hydroxyhippuric acid is generated via medium-chain acyl-CoA dehydrogenase (MCAD)-dependent β-oxidation of microbially-produced 3-(4-hydroxyphenyl)propionic acid, followed by host glycine conjugation. 4-Hydroxyhippuric acid can be simultaneously detected in urine as a biomarker of dietary polyphenol intake .

HY-W010164

4-Hydroxybenzoate sodium	Biochemical Assay Reagents	Others
4-Hydroxybenzoate sodium, also known as sodium p-hydroxybenzoate or sodium paraben, is commonly used as a food preservative and cosmetic preservative. It can also be used as an additive in a variety of other products, including pharmaceuticals, personal care products, and industrial products. Additionally, 4-Hydroxybenzoate sodium has the potential to function as xenoestrogens, which may mimic the effects of estrogen in the body and affect hormonal balance.

HY-N10403

4-Hydroxyestradiol 1 Publications Verification 4-hydroxy-17β-estradiol	Drug Metabolite Endogenous Metabolite	Cancer
4-Hydroxyestradiol (4-Hydroxy-17β-estradiol) is an endogenous metabolite of Estradiol (HY-B0141). 4-Hydroxyestradiol is carcinogenic and shows mutagenic activity in breast epithelial cells. 4-Hydroxyestradiol inhibits the binding of Estradiol to the estrogen receptor in a competitive manner, with a K_i of 0.48 nM .

HY-W091541

4-Hydroxy-1H-indole-3-carbaldehyde 4-hydroxyindole-3-carboxaldehyde	Endogenous Metabolite	Others Inflammation/Immunology
4-Hydroxy-1H-indole-3-carbaldehyde (4-Hydroxyindole-3-carboxaldehyde) is a plant metabolite. 4-Hydroxy-1H-indole-3-carbaldehyde can be isolated from Capparis spinosa L. 4-Hydroxy-1H-indole-3-carbaldehyde can be used in the synthesis of fluorescent probe. 4-Hydroxy-1H-indole-3-carbaldehyde can be used in the study of inflammation-related diseases .

HY-W008772S

4-Hydroxymephenytoin-d3	Drug Metabolite	Others
4-Hydroxymephenytoin-d₃ is the deuterium labeled 4-Hydroxymephenytoin. 4-Hydroxymephenytoin is a metabolism of an antiepileptic agent mephenytoin, which is used as a CYP2C19 substrate .

HY-W036733

4-Hydroxy-4-methylcyclohexanone	Biochemical Assay Reagents	Others
4-Hydroxy-4-methylcyclohexanone is a useful synthetic reagent extracted from patent JP2009022162A. 4-Hydroxy-4-methylcyclohexanone can be used to synthesize trans-4-amino-1-methylcyclohexanol which is intermediate of pharmaceutical synthesis .

HY-W015823

4-Hydroxybenzyl cyanide	Endogenous Metabolite	Others
4-Hydroxybenzyl cyanide is an aromatic nitrile compound and also a precursor for tyramine synthesis. 4-Hydroxybenzyl cyanide exhibits strong antioxidant activity .

HY-W004078

4-Hydroxybenzylamine	Endogenous Metabolite	Metabolic Disease
4-Hydroxybenzylamine is a natural biogenic amine. 4-Hydroxybenzylamine can be produced through the breakdown metabolism of glucosinolates, with glutamine serving as the non-classical ammonia donor. 4-Hydroxybenzylamine can be utilized for the study of plant amine biosynthesis .

HY-W014937

4-Hydroxybenzophenone	Drug Intermediate	Cancer
4-Hydroxybenzophenone is an intermediate for synthesizing Tamoxifen (HY-13757A) and can be used as a source for chemical synthesis, UV protection products, and UV-absorbing ingredients in cosmetics .

HY-133116

4-Hydroxyatomoxetine	Adrenergic Receptor	Neurological Disease
4-Hydroxyatomoxetine is an active metabolite of Atomoxetine. 4-Hydroxyatomoxetine is metabolized by the enzyme cytochrome P450 2D6 (CYP2D6). Atomoxetine hydrochloride is a potent and selective noradrenalin re-uptake inhibitor (K_i values are 5 nM, 77 nM and 1451 nM for inhibition of radioligand binding to human NET, SERT and DAT respectively) .

HY-W009300

4-Hydroxyestrone 1 Publications Verification 4-OHE1	Endogenous Metabolite Estrogen Receptor/ERR Sirtuin MDM-2/p53 PDI Ferroptosis Reactive Oxygen Species (ROS)	Neurological Disease Metabolic Disease Cancer
4-Hydroxyestrone (4-OHE1) is a brain-penetrant estrogen metabolite. 4-Hydroxyestrone shows neuroprotective effects involving increased cytoplasmic localization of p53 resulting from SIRT1-mediated p53 deacetylation. 4-Hydroxyestrone relies on PDI to mediate its protective effect against chemically induced ferroptosis in estrogen receptor-negative cancer cells. 4-Hydroxyestrone inhibits lipid peroxidation and lipid-ROS accumulation. 4-Hydroxyestrone blocks preovulatory luteinizing hormone surges in Rattus norvegicus. 4-Hydroxyestrone can be used for the researches of neurodegeneration, breast cancer and endocrine disease .

HY-Y0264S

4-Hydroxybenzoic acid-13C6	Isotope-Labeled Compounds	Infection
4-Hydroxybenzoic acid- ¹³C6 is the ¹³C labeled isotope of 4-Hydroxybenzoic acid- ¹³C6.4-Hydroxybenzoic acid is a phenolic derivative of benzoic acid, which can inhibit most Gram-positive bacteria and some Gram-negative bacteria with an IC50 value of 160 μg/mL.

HY-W104819

4-Hydroxyphenylglyoxylate 4-hydroxyphenylglyoxylic acid; 4-HPGA	Acyltransferase Carnitine Palmitoyltransferase (CPT)	Metabolic Disease
4-Hydroxyphenylglyoxylate (4-Hydroxyphenylglyoxylic acid) is an inhibitor of carnitine palmitoyltransferase I (CPT I). 4-Hydroxyphenylglyoxylate can be used to study sensitivity changes in CPT I of liver mitochondria and fatty acid oxidation by isolated hepatocytes. 4-Hydroxyphenylglyoxylate can inhibits fatty acid oxidation .

HY-118796

4-Hydroxy MET 4-HO-MET; 4-hydroxy-N-methyl-N-ethyltryptamine	5-HT Receptor Serotonin Transporter	Neurological Disease
4-Hydroxy MET (4-HO-MET; 4-Hydroxy-N-methyl-N-ethyltryptamine) is a synthetic tryptamine psychoactive substance. 4-Hydroxy MET is a partial 5-HT2A receptor agonist, a serotonin transporter inhibitor and weak norepinephrine transporter inhibitor. 4-Hydroxy MET affects emotional, motoric, and cognitive functions via serotonergic hallucinogenic activity .

HY-W766140

4-Hydroxy duloxetine β-D-glucuronide sodium 4-hydroxy duloxetine glucuronide sodium; LY550408 sodium	Drug Metabolite	Metabolic Disease
4-Hydroxy duloxetine β-D-glucuronide (4-Hydroxy duloxetine glucuronide) sodium is a major metabolite of Duloxetine (HY-B0161). 4-Hydroxy duloxetine β-D-glucuronide sodium is promising for research of hepatic or renal impairment .

HY-W088191

4-Hydroxybenzamide	Drug Intermediate	Cardiovascular Disease
4-Hydroxybenzamide, found in the herb of Berberis pruinosa, is a known natural product that has potential to slow down the progression of atherosclerosis .

HY-W612296

4-Hydroxybutanal	PROTAC Linkers	Cancer
4-Hydroxybutanal is a PROTAC linker that can be used in the synthesis of PROTACs.

HY-W088320

4-Hydroxydiphenylamine p-Anilinophenol; 4-hydroxy-DPA	Drug Intermediate	Others
4-Hydroxydiphenylamine (p-Anilinophenol; 4-Hydroxy-DPA) is an aromatic amine organic compound. 4-Hydroxydiphenylamine has antioxidant activity and is also used as a catalyst or intermediate in some chemical reactions to synthesize other compounds. 4-Hydroxydiphenylamine can be used in the research of environmental science and toxicology .

HY-W014937S1

4-Hydroxybenzophenone-d5	Isotope-Labeled Compounds	Others
4-Hydroxybenzophenone-d₅ is the deuterium labeled 4-Hydroxybenzophenone .

HY-N1902S1

4-Hydroxyphenylacetic acid-d4	Keap1-Nrf2 Endogenous Metabolite	Metabolic Disease
4-Hydroxyphenylacetic acid-d₄ is the deuterium labeled 4-Hydroxyphenylacetic acid . 4-hydroxyphenylacetic acid, a major microbiota-derived metabolite of polyphenols, is involved in the antioxidative action. 4-hydroxyphenylacetic acid induces expression of Nrf2 .

HY-B2150

4-Hydroxyantipyrine 4-hydroxyphenazone; NSC 174055	Drug Metabolite	Others
4-Hydroxyantipyrine (4-Hydroxyphenazone; NSC 174055) is the major metabolite of Antipyrine (HY-B0171), can be as a biodistribution promoter. 4-Hydroxyantipyrine can increase distribution of concentration ratio of Citicoline and Antipyrine in the brain .

HY-33528

4-Hydroxyphthalic acid 4-hydroxybenzene-1,2-dicarboxylic acid	MOFs	Others
4-Hydroxyphthalic acid (4-Hydroxybenzene-1,2-dicarboxylic acid) is a metal-organic framework (MOF).

HY-12767S

4-Hydroxyphenyl Carvedilol-d5 4-hydroxycarvedilol-d₅	Drug Metabolite Isotope-Labeled Compounds	Cardiovascular Disease Inflammation/Immunology Cancer
4-Hydroxyphenyl Carvedilol-d₅ is the deuterium labeled 4-Hydroxyphenyl Carvedilol.

HY-33914

4-Hydroxymethylpyrazole	Drug Metabolite	Metabolic Disease
4-Hydroxymethylpyrazole is the primary metabolite of Fomepizole (HY-B0876) produced through hepatic oxidative metabolism. 4-Hydroxymethylpyrazole exhibits a plasma concentration that is positively correlated with the administered dosage of Fomepizole, and it demonstrates a relatively short half-life. 4-Hydroxymethylpyrazole demonstrates inhibitory effects on alcohol dehydrogenase (ADH) in both humans and monkeys, but its inhibition constant is significantly higher than that of Fomepizole, rendering its in vivo impact negligible .

HY-N16394

4-Hydroxyscytalone	Endogenous Metabolite	Cancer
4-Hydroxyscytalone (Compound 3) is a microbial secondary metabolite. 4-Hydroxyscytalone can be isolated from the oak fungus Diplodia corticola. 4-Hydroxyscytalone has toxicity against Artemia salina with a LC50 of 90.6 μ/mL, but no significant antifungal activity. 4-Hydroxyscytalone can be used for cancer therapy research .

HY-177977

4-Hydroxyalprenolol Alp2b	Drug Metabolite	Cardiovascular Disease
4-Hydroxyalprenolol (Alp2b) is a metabolite of β-receptor blocker Alprenolol (HY-B1517) .

HY-W098556

4-Hydroxyhygric acid	Insecticide	Infection
4-Hydroxyhygric acid is a compound isolated from leaves of five species of the leguminous tropical tree Copuiferq. 4-Hydroxyhygric acid is the inhibitor of larval development of the seed-feeding bruchid beetle Callosobruchus maculatus and to have significant feeding deterrence of the leaf-feeding lepidopteran Spodoprera littoralis .

HY-135325

4-Hydroxyacetophenone oxime	Drug Metabolite	Inflammation/Immunology
4-Hydroxyacetophenone oxime is an impurity of Acetaminophen (Paracetamol). Acetaminophen is a potent cyclooxygenase-2 (COX-2) and hepatic N-acetyltransferase 2 (NAT2) inhibitor, and used antipyretic and analgesic agent .

HY-W328786

4-Hydroxy-BHT	Drug Metabolite	Metabolic Disease
4-Hydroxy-BHT is metabolite of Butylated hydroxytoluene (HY-Y0172) and used as an indicator of exposure to Butylated hydroxytoluene. Butylated hydroxytoluene is a phenolic antioxidant used widely in processed foods and petroleum products .

HY-12767S1

Carvedilol metabolite 4-Hydroxyphenyl Carvedilol-d4 4-hydroxyphenyl Carvedilol-d₄; 4-hydroxycarvedilol-d₄	Isotope-Labeled Compounds	Cancer
Carvedilol metabolite 4-Hydroxyphenyl Carvedilol-d₄ is deuterated labeled Carvedilol metabolite 4-Hydroxyphenyl Carvedilol (HY-12767). 4-Hydroxyphenyl Carvedilol is a metabolite of Carvedilol.

HY-N10403R

4-Hydroxyestradiol (Standard) 4-hydroxy-17β-estradiol (Standard)	Reference Standards Drug Metabolite Endogenous Metabolite	Cancer
ABZ-amine (Standard) is the analytical standard of ABZ-amine. This product is intended for research and analytical applications. ABZ-amine (Amino albendazole) is an impurity of Albendazole. Albendazole is a member of the benzimidazole compounds used as a agent indicated for the treatment of a variety of worm infestations .

HY-B2150S

4-Hydroxyantipyrine-d3 4-hydroxyphenazone-d₃; NSC 174055-d₃	Drug Metabolite Isotope-Labeled Compounds	Others
4-Hydroxyantipyrine-d₃ is the deuterium labeled 4-Hydroxyantipyrine. 4-Hydroxyantipyrine is the major metabolite of Antipyrine, can be as a biodistribution promoter. 4-Hydroxyantipyrine can increase distribution of concentration ratio of Antipyrine in the brain .

HY-115354S

4-Hydroxy Alprazolam-d5 4-hydroxyalprazolam-d₅; RS-4-hydroxyalprazolam-d₅	Isotope-Labeled Compounds	Others
4-Hydroxy Alprazolam-d5 (4-Hydroxyalprazolam-d5; RS-4-Hydroxyalprazolam-d5) is the deuterium labeled 4-hydroxy Alprazolam (HY-115354) .

HY-B2150R

4-Hydroxyantipyrine (Standard) 4-hydroxyphenazone (Standard); NSC 174055 (Standard)	Reference Standards Drug Metabolite	Others
4-Hydroxyantipyrine (Standard) is the analytical standard of 4-Hydroxyantipyrine. This product is intended for research and analytical applications. 4-Hydroxyantipyrine (4-Hydroxyphenazone; NSC 174055) is the major metabolite of Antipyrine (HY-B0171), can be as a biodistribution promoter. 4-Hydroxyantipyrine can increase distribution of concentration ratio of Citicoline and Antipyrine in the brain .

HY-100634SA

4-Hydroxypropranolol-d7 (±)-4-hydroxy Propranolol-d₇	Isotope-Labeled Compounds Adrenergic Receptor	Neurological Disease
4-Hydroxypropranolol-d₇ is the deuterium labeled 4-Hydroxypropranolol hydrochloride. 4-Hydroxypropranolol hydrochlorid is an active metabolite of Propranolol. 4-Hydroxypropranolol hydrochlorid is of comparable potency to Propranolol. 4-Hydroxypropranolol hydrochlorid inhibits β1- and β2-adrenergic receptors with pA2 values of 8.24 and 8.26, respectively. 4-Hydroxypropranolol hydrochlorid has intrinsic sympathomimetic activity, membrane stabilizing activity and potent antioxidant properties .

製品番号	製品名	Type

HY-NP141

NP-BSA

4-hydroxy-3-nitrophenylacetyl-bovine serum albumin

生化学アッセイ試薬

NP-BSA (4-Hydroxy-3-nitrophenylacetyl-bovine serum albumin) is an antigen-adjuvant conjugate of 4-Hydroxy-3-nitrophenylacetyl (NP) conjugated to bovine serum albumin (BSA), which is an immune complex. NP-BSA is taken up, processed, and presented by antigen-presenting cells to stimulate T-cell proliferation and the production of antigen-specific antibodies. NP-BSA can be used in the research of immunological vaccines .

HY-NP133A

NP-KLH,Type II 4-hydroxy-3-nitrophenylacetyl-Keyhole Limpet Hemocyanin,Type II	生化学アッセイ試薬
NP-KLH,Type II is a complex formed by 4-Hydroxy-3-nitrophenylacetyl (NP, a hapten) with Keyhole Limpet Hemocyanin (KLH, a carrier protein). NP-KLH,Type II can induce specific humoral immune responses and NP-specific antibodies production. NP-KLH,Type II can act as a specific antigen tool used for immunological experiments .

HY-W010164

4-Hydroxybenzoate sodium

生化学アッセイ試薬

4-Hydroxybenzoate sodium, also known as sodium p-hydroxybenzoate or sodium paraben, is commonly used as a food preservative and cosmetic preservative. It can also be used as an additive in a variety of other products, including pharmaceuticals, personal care products, and industrial products. Additionally, 4-Hydroxybenzoate sodium has the potential to function as xenoestrogens, which may mimic the effects of estrogen in the body and affect hormonal balance.

HY-W002879

4-Hydroxyphenylboronic acid pinacol ester

生化学アッセイ試薬

4-Hydroxyphenylboronic acid pinacol ester is a ROS-responsive component. 4-Hydroxyphenylboronic acid pinacol ester can structurally modify hyaluronic acid to prepare ROS-responsive intelligent nanocarriers and compound delivery systems. 4-Hydroxyphenylboronic acid pinacol ester endows hyaluronic acid-based nanocarriers with ROS responsiveness, enabling them to rapidly release the encapsulated Curcumin (HY-N0005) in the presence of reactive oxygen species. 4-Hydroxyphenylboronic acid pinacol ester is applicable to research related to periodontitis. 4-Hydroxyphenylboronic acid pinacol ester can also be used for the synthesis of boronic acid-modified resins .

HY-W036733

4-Hydroxy-4-methylcyclohexanone	生化学アッセイ試薬
4-Hydroxy-4-methylcyclohexanone is a useful synthetic reagent extracted from patent JP2009022162A. 4-Hydroxy-4-methylcyclohexanone can be used to synthesize trans-4-amino-1-methylcyclohexanol which is intermediate of pharmaceutical synthesis .

HY-Y1634

4-Hydroxy-6-methyl-2-pyrone	生化学アッセイ試薬
4-Hydroxy-6-methyl-2-pyrone is an organic reagent that reacts with αβ-unsaturated acyl chlorides .

HY-W016806

Sodium methylparaben, 99% 5+ Cited Publications Sodium methyl 4-hydroxybenzoate, 99%	生化学アッセイ試薬
Sodium methylparaben, 99% (Sodium methyl 4-hydroxybenzoate, 99%) is an antifungal agent .

HY-W000949

4-(Hydroxymethyl)benzeneboronic acid	生化学アッセイ試薬
4-(Hydroxymethyl)benzeneboronic acid is an important intermediate. 4-(Hydroxymethyl)benzeneboronic acid can be used for the synthesis of other active compounds .

HY-W017384

4-(Hydroxymethyl)benzoic acid	生化学アッセイ試薬
4-(Hydroxymethyl)benzoic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W016331

9H-Carbazol-4-ol 4-hydroxycarbazole	生化学アッセイ試薬
9H-Carbazol-4-ol (4-Hydroxycarbazole) can be used as an aromatic heterocyclic compound with widespread applications in organic synthesis, as well as certain biochemical and physiological effects. 9H-Carbazol-4-ol is a kind of biological materials or organic compounds that are widely used in life science research .

HY-W016491

Isopropyl 4-hydroxybenzoate Isopropylparaben	生化学アッセイ試薬
Isopropyl 4-hydroxybenzoate (Isopropylparaben) is an antimicrobial and antioxidant agent .

HY-W012927

4-Hydroxy-5-methylfuran-3(2H)-one Chicory furaneol	生化学アッセイ試薬
4-Hydroxy-5-methylfuran-3(2H)-one (Chicory furaneol) can be used to assay oxidoreductase activity. 4-Hydroxy-5-methylfuran-3(2H)-one is a kind of biological materials or organic compounds that are widely used in life science research .

HY-B1431B

Butylparaben, ≥99% Butyl parahydroxybenzoate, ≥99%; Butyl 4-hydroxybenzoate, ≥99%	生化学アッセイ試薬
Butylparaben, ≥99% (Butyl parahydroxybenzoate, ≥99%) is a widely used preservative.

HY-W007807

4-Hydroxy-3,5-dimethylbenzaldehyde	生化学アッセイ試薬
4-Hydroxy-3,5-dimethylbenzaldehyde is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W001217

4-Hydroxy-1-indanone	生化学アッセイ試薬
4-Hydroxy-1-indanone is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W099118

Sodium ethylparaben Sodium ethyl 4-hydroxybenzoate	生化学アッセイ試薬
Sodium ethylparaben (Sodium ethyl 4-hydroxybenzoate) acts as a water soluble antiseptic usually employed as safe for cosmetics .

HY-W016483

Ethyl (4-hydroxyphenyl)acetate	生化学アッセイ試薬
Ethyl (4-hydroxyphenyl)acetate is a chemical derivative used as a carbon source.

HY-158268

4-Hydroxynonenal/BSA	生化学アッセイ試薬
4-Hydroxynonenal/BSA is a biochemical reagent that can be used as a biological material or organic compound for life science related research .

HY-W791535

4-Hydroxy propofol 1-O-β-D-glucuronide

生化学アッセイ試薬

4-Hydroxy propofol 1-O-β-D-glucuronide is a class of biochemical reagents used in the study of glycobiology. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It deals with carbohydrate chemistry, glycan formation and degradation enzymology, protein-glycan recognition, and the role of glycans in biological systems. The field is closely related to basic research, biomedicine and biotechnology .

HY-W700218

4-Hydroxy propofol 4-O-β-D-Glucuronide

生化学アッセイ試薬

4-Hydroxy propofol 4-O-β-D-Glucuronide is a class of biochemical reagents used in the study of glycobiology. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It deals with carbohydrate chemistry, glycan formation and degradation enzymology, protein-glycan recognition, and the role of glycans in biological systems. The field is closely related to basic research, biomedicine and biotechnology .

HY-W016806R

Sodium methylparaben (Standard) Sodium methyl 4-hydroxybenzoate (Standard)	生化学アッセイ試薬
Sodium methylparaben (Standard) is the analytical standard of Sodium methylparaben. This product is intended for research and analytical applications. Sodium methylparaben (Sodium methyl 4-hydroxybenzoate) is an antifungal agent .

HY-W700451

4'-Hydroxy atomoxetine β-D-glucuronide	生化学アッセイ試薬
4'-Hydroxy atomoxetine β-D-glucuronide is a kind of biochemical reagent.

HY-158268B

4-Hydroxynonenal/KLH	生化学アッセイ試薬
4-Hydroxynonenal/KLH is an antigen-adjuvant conjugate conjugate of 4-Hydroxynonenal (HY-113466) and KLH. By conjugating the antigen with a protein adjuvant, the production of antigen-specific antibodies in vaccine models can be enhanced. The conjugate does not affect protein folding or disrupt major epitopes, and can enhance cross-presentation and the production of antigen-specific T cells.

HY-158268A

4-Hydroxynonenal/OVA

生化学アッセイ試薬

4-Hydroxynonenal/OVA is an antigen-adjuvant conjugate conjugate of 4-Hydroxynonenal (HY-113466) and ovalbumin (OVA). By conjugating the antigen with a protein adjuvant, the production of antigen-specific antibodies in vaccine models can be enhanced. The conjugate does not affect protein folding or disrupt major epitopes, and can enhance cross-presentation and the production of antigen-specific T cells.

HY-W010164R

4-Hydroxybenzoate sodium (Standard)

生化学アッセイ試薬

4-Hydroxybenzoate (sodium) (Standard) is the analytical standard of 4-Hydroxybenzoate (sodium). This product is intended for research and analytical applications. 4-Hydroxybenzoate sodium, also known as sodium p-hydroxybenzoate or sodium paraben, is commonly used as a food preservative and cosmetic preservative. It can also be used as an additive in a variety of other products, including pharmaceuticals, personal care products, and industrial products. Additionally, 4-Hydroxybenzoate sodium has the potential to function as xenoestrogens, which may mimic the effects of estrogen in the body and affect hormonal balance.

HY-W016491R

Isopropyl 4-hydroxybenzoate (Standard) Isopropylparaben (Standard)	生化学アッセイ試薬
Isopropyl 4-hydroxybenzoate (Standard) is the analytical standard of Isopropyl 4-hydroxybenzoate. This product is intended for research and analytical applications. Isopropyl 4-hydroxybenzoate (Isopropylparaben) is an antimicrobial and antioxidant agent .

HY-W099118R

Sodium ethylparaben (Standard) Sodium ethyl 4-hydroxybenzoate (Standard)	生化学アッセイ試薬
Sodium ethylparaben (Standard) is the analytical standard of Sodium ethylparaben. This product is intended for research and analytical applications. Sodium ethylparaben (Sodium ethyl 4-hydroxybenzoate) acts as a water soluble antiseptic usually employed as safe for cosmetics .

HY-W017384R

4-(Hydroxymethyl)benzoic acid (Standard)	生化学アッセイ試薬
4-(Hydroxymethyl)benzoic acid (Standard) is the analytical standard of 4-(Hydroxymethyl)benzoic acid. This product is intended for research and analytical applications. 4-(Hydroxymethyl)benzoic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

製品番号	製品名	Category	Target	構造式

HY-113466

4-Hydroxynonenal 15+ Cited Publications 4-HNE	Neurological Disease Classification of Application Fields Ketones, Aldehydes, Acids Disease markers Nervous System Disorder Endogenous metabolite Disease Research Fields Cancer	Aldehyde Dehydrogenase (ALDH) Endogenous Metabolite
4-Hydroxynonenal (4-HNE) is an α,β unsaturated hydroxyalkenal and an oxidative/nitrosative stress biomarker. 4-Hydroxynonenal is a substrate and an inhibitor of acetaldehyde dehydrogenase 2 (ALDH2). 4-Hydroxynonenal can modulate a number of signaling processes mainly through forming covalent adducts with nucleophilic functional groups in proteins, nucleic acids, and membrane lipids. 4-Hydroxynonenal plays an important role in cancer through mitochondria .

HY-W011303

Phytosphingosine 4 Publications Verification 4-hydroxysphinganine	Infection 天然物 Human Gut Microbiota Metabolites Classification of Application Fields Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification Cancer	Apoptosis Endogenous Metabolite Fungal Free Fatty Acid Receptor
Phytosphingosine is a phospholipid with anti-inflammatory, antibacterial, and anti-cancer activities, which can induce apoptosis. Phytosphingosine is an immune regulator and can be used in the study of inflammatory skin diseases. Phytosphingosine is also an activator of GPR120 with an IC₅₀ value of 33.4 μM and can be used in the study of type II diabetes .

HY-Y0264

4-Hydroxybenzoic acid	Classification of Application Fields Plants Endogenous metabolite Infection Human Gut Microbiota Metabolites Monophenols Microorganisms Leguminosae Ketones, Aldehydes, Acids Phenols Glycyrrhiza uralensis Fisch. Disease Research Fields Source Classification	Endogenous Metabolite Bacterial
4-Hydroxybenzoic acid, a phenolic derivative of benzoic acid, could inhibit most gram-positive and some gram-negative bacteria, with an IC₅₀ of 160 μg/mL.

HY-N1902

4-Hydroxyphenylacetic acid	Structural Classification Human Gut Microbiota Metabolites Monophenols Classification of Application Fields Phenols Metabolic Disease Plants Compositae Endogenous metabolite Erythrina latissima E. Mey. Disease Research Fields Source Classification	Keap1-Nrf2 Endogenous Metabolite
4-hydroxyphenylacetic acid, a major microbiota-derived metabolite of polyphenols, is involved in the antioxidative action. 4-hydroxyphenylacetic acid induces expression of Nrf2 .

HY-N0349

Methyl paraben 5+ Cited Publications Methyl 4-hydroxybenzoate	Structural Classification Tsuga dumosa Classification of Application Fields Plants Endogenous metabolite Infection Monophenols Animals Pinaceae Phenols Cosmetic Research Disease Research Fields Source Classification	Environmental Pollutants Endogenous Metabolite Bacterial
Methyl Paraben is a standardized methyl paraben allergen isolated from Yunnan hemlock (Tsuga dumosa). Methyl Paraben is commonly used as a stable, non-volatile preservative. Methyl Paraben increases histamine release and cellular regulation of immunity, blocks sodium channels, and prevents ischemia-reperfusion injury .

HY-W008772

4-Hydroxymephenytoin	Monophenols Classification of Application Fields Other Diseases Phenols Endogenous metabolite Disease Research Fields Source Classification	Drug Metabolite
4-Hydroxymephenytoin is a metabolism of an antiepileptic agent mephenytoin, which is used as a CYP2C19 substrate.

HY-N7204

4-Hydroxyderricin 1 Publications Verification	Chalcones Monophenols Flavonoids Phenols Umbelliferae Plants Ondetia linearis Benth.	Monoamine Oxidase Dopamine β-hydroxylase Apoptosis
4-Hydroxyderricin, the major active ingredients of Angelica keiskei Koidzumi, is an orally active, potent selective MAO-B (Monoamine oxidase inhibitors) inhibitor with an IC₅₀ of 3.43 μM. 4-Hydroxyderricin also mildly inhibits dopamine β (DBH)-hydroxylase activity. 4-Hydroxyderricin has antidepressant activity, anti-allergic, anti-diabetic, anti-oxidant, and antitumor effects. 4-Hydroxyderricin promotes apoptosis and cell cycle arrest through regulating PI3K/AKT/mTOR pathway in hepatocellular cells. 4-Hydroxyderricin inhibits osteoclast formation and accelerates osteoblast differentiation . 4-Hydroxyderricin is promising for research of inflammatory diseases .

HY-Y0073

4-Hydroxyacetophenone 1 Publications Verification P-hydroxyacetophenone	Monophenols Classification of Application Fields Ketones, Aldehydes, Acids Phenols Plants Compositae Inflammation/Immunology Disease Research Fields Artemisia capillaris Thunb. Source Classification	HBV Myosin
4-Hydroxyacetophenone (P-hydroxyacetophenone) is a major hepatoprotective and choleretic compound found in Artemisia and Illicium plants, exhibiting antiviral and anti-inflammatory effects against hepatitis B virus. Additionally, 4-Hydroxyacetophenone inhibits cancer cell adhesion, invasion, and migration by remodeling actin. 4-Hydroxyacetophenone holds promise for research in the fields of inflammatory diseases and cancer .

HY-76316

Bergaptol 5-hydroxypsoralen; 4-hydroxybergapten	Structural Classification Monophenols other families Classification of Application Fields Coumarins Phenols Phenylpropanoids Plants Disease Research Fields Source Classification Cancer	Cytochrome P450
Bergaptol is an inhibitor of debenzylation of the CYP3A4 enzyme with an IC₅₀ of 24.92 μM. Recent studies have shown that it has anti-proliferative and anti-cancer properties .

HY-N2026

Propylparaben 1 Publications Verification Propyl parahydroxybenzoate; Propyl 4-hydroxybenzoate	Infection Structural Classification 天然物 Monophenols Preservatives Classification of Application Fields Phenols Cosmetic Research Endogenous metabolite Disease Research Fields Source Classification Food Research	Bacterial Estrogen Receptor/ERR Sodium Channel PI3K JNK Akt Apoptosis
Propylparaben (Propyl parahydroxybenzoate) is an antibacterial preservative that can be produced by plants and bacteria. Propylparaben is an orally active weak estrogen receptor agonist. Propylparaben regulates the PI3K-AKT and JNK signaling pathways, and induces oxidative stress. Propylparaben is commonly used in cosmetics, pharmaceuticals and foods, and can be used in studies related to ovarian aging and myocardial ischemia-reperfusion injury .

HY-107818

4-Hydroxychalcone 2 Publications Verification	Cardiovascular Disease Structural Classification Chalcones Monophenols Flavonoids other families Classification of Application Fields Phenols Plants Disease Research Fields Source Classification	ERK Akt
4-Hydroxychalcone is an orally active flavonoid precursor. 4-Hydroxychalcone inhibits VEGF- and bFGF-induced phosphorylation of ERK1/2 and Akt. 4-Hydroxychalcone suppresses resistant hypertension by alleviating hyperaldosteronism, inflammation and renal injury in cryptochrome gene knockout mice. 4-Hydroxychalcone possesses anti-angiogenic activity .\n

HY-Y0892

4-Hydroxybenzyl alcohol 1 Publications Verification	Neurological Disease Classification of Application Fields Plants Endogenous metabolite Human Gut Microbiota Metabolites Monophenols Microorganisms Gastrodia elata Bl. Orchidaceae Phenols Inflammation/Immunology Disease Research Fields Source Classification	Apoptosis Endogenous Metabolite
4-Hydroxybenzyl alcohol is a phenolic compound widely distributed in various kinds of plants. Anti-inflammatory, anti-oxidant, anti-nociceptive activity. Neuroprotective effect. Inhibitor of tumor angiogenesis and growth .

HY-N3002

α-Arbutin 4-hydroxyphenyl α-D-glucopyranoside	Monophenols Classification of Application Fields Phenols Metabolic Disease Cosmetic Research Ericaceae Plants Disease Research Fields Source Classification	Tyrosinase
α-Arbutin (4-Hydroxyphenyl α-D-glucopyranoside) is a tyrosinase inhibitor, which is used as an effective skin whiteners. α-Arbutin is promising for research of various diseases such as hyperpigmentation disorders, types of cancers, central nervous system disorders, osteoporosis, diabetes .

HY-B1431

Butylparaben 2 Publications Verification Butyl parahydroxybenzoate; Butyl paraben; Butyl 4-hydroxybenzoate	Infection Structural Classification Monophenols Classification of Application Fields Phenols Cosmetic Research Endogenous metabolite Disease Research Fields Source Classification	Environmental Pollutants Endogenous Metabolite Bacterial DNA/RNA Synthesis
Butylparaben is an organic compound that has proven to be a very successful antimicrobial preservative in cosmetics, can also be used in active molecule suspensions, and as a food flavoring additive .

HY-B0934

Ethylparaben Ethyl parahydroxybenzoate; Ethyl 4-hydroxybenzoate	Structural Classification Monophenols Preservatives Classification of Application Fields Other Diseases Phenols Cosmetic Research Disease Research Fields Source Classification Food Research	Environmental Pollutants Bacterial Fungal
Ethylparaben is the ethyl ester of paraben and is used as an antifungal preservative and food additive .

HY-N6856

4-Hydroxycoumarin	Infection Classification of Application Fields Coumarins Phenylpropanoids Endogenous metabolite Disease Research Fields Source Classification	Bacterial Endogenous Metabolite
4-Hydroxycoumarin is an orally active coumarin derivative, one of the most versatile heterocyclic scaffolds, often used in the synthesis of various organic compounds. 4-Hydroxycoumarin possesses both electrophilic and nucleophilic properties. 4-Hydroxycoumarin is an HIV protease inhibitor and tyrosine kinase inhibitor. 4-Hydroxycoumarin has anti-inflammatory, antibacterial and anti-tumor effects .

HY-30267

4-Hydroxyphenyl acetate 2 Publications Verification 4-HPA; 4-Acetoxyphenol	Monophenols Classification of Application Fields Other Diseases Phenols Endogenous metabolite Disease Research Fields Source Classification	Quinone Reductase Endogenous Metabolite
4-Hydroxyphenyl acetate (4-HPA) is a natural antioxidant and protects cells from oxidative stress-induced necrosis. 4-Hydroxyphenyl acetate blocks the increase of cellular ROS induced by oxidative stress, and up-regulates NQO1 and HO-1 genes by stabilizing and inducing the nuclear translocation of NRF2 transcription factor .

HY-W005288

4-Vinylphenol (10% in Propylene glycol) 1 Publications Verification 4-hydroxystyrene	Monophenols Microorganisms Classification of Application Fields Rubiaceae Phenols Plants Endogenous metabolite Disease Research Fields Hedyotis diffusa Willd. Source Classification Cancer	Apoptosis Endogenous Metabolite
4-Vinylphenol is found in the medicinal herb Hedyotis diffusa Willd, wild rice and is also the metabolite of p-coumaric and ferulic acid by lactic acid bacteria in wine. 4-Vinylphenol induces apoptosis and inhibits blood vessels formation and suppresses invasive breast tumor growth in vivo .

HY-N6858

4-Hydroxyisoleucine 4-hydroxy-L-isoleucine	Structural Classification other families Classification of Application Fields Leguminosae Ketones, Aldehydes, Acids Metabolic Disease Plants Trigonella foenum-graecum Linn. Disease Research Fields Source Classification	Others
4-Hydroxyisoleucine is an orally active amino acid that can be isolated from fenugreek seeds. 4-Hydroxyisoleucine displays insulinotropic and antidiabetic properties .

HY-N2208

4-Hydroxylonchocarpin 2 Publications Verification	Classification of Application Fields Metabolic Disease Plants Infection Chalcones Flavonoids Leguminosae Phenols Polyphenols Psoralea corylifolia L. Inflammation/Immunology Disease Research Fields Source Classification	p38 MAPK Apoptosis Reactive Oxygen Species (ROS)
4-Hydroxylonchocarpin is a chalcone compound. 4-Hydroxylonchocarpin enhances the phosphorylation of p38 MAPK, JNK and ERK. 4-Hydroxylonchocarpin induces reactive oxygen species (ROS) and apoptosis in liver cancer cells. 4-Hydroxylonchocarpin has various pharmacological activities, including antibacterial, anticancer, anti-retroviral, anti-tuberculosis, anti-malarial and anti-inflammatory activities .

HY-113158

4-Hydroxyhippuric acid	Immune System Disorder Disease markers Endogenous metabolite	Drug Metabolite
4-Hydroxyhippuric acid is a metabolite of polyphenols. 4-Hydroxyhippuric acid is generated via medium-chain acyl-CoA dehydrogenase (MCAD)-dependent β-oxidation of microbially-produced 3-(4-hydroxyphenyl)propionic acid, followed by host glycine conjugation. 4-Hydroxyhippuric acid can be simultaneously detected in urine as a biomarker of dietary polyphenol intake .

HY-N2535

Coniferaldehyde 1 Publications Verification 4-hydroxy-3-methoxycinnamaldehyde	Monophenols other families Classification of Application Fields Simple Phenylpropanols Phenols Phenylpropanoids Plants Inflammation/Immunology Disease Research Fields Source Classification	Keap1-Nrf2 Apoptosis
Coniferaldehyde (4-Hydroxy-3-methoxycinnamaldehyde) is an effective inducer of heme oxygenase-1 (HO-1). Coniferaldehyde inhibits LPS-induced apoptosis through the PKCα/β II/Nrf-2/HO-1 dependent pathway in RAW264.7 macrophage cells. Coniferaldehyde has antioxidant and anti-inflammatory activities .

HY-N1434

Methyl p-coumarate Methyl 4-hydroxycinnamate	Infection Monophenols other families Classification of Application Fields Simple Phenylpropanols Phenols Phenylpropanoids Plants Disease Research Fields Source Classification	Fungal
Methyl p-coumarate (Methyl 4-hydroxycinnamate), an orally active esterified derivative of p-Coumaric acid (pCA), can be isolated from the flower of Trixis michuacana var longifolia. Methyl p-coumarate could inhibit the melanin formation in B16 mouse melanoma cells. Methyl p-coumarate also has strong in vitro inhibitory effect on A. alternata and other pathogens .

HY-N10403

4-Hydroxyestradiol 1 Publications Verification 4-hydroxy-17β-estradiol	Classification of Application Fields Phenols Polyphenols Endogenous metabolite Disease Research Fields Steroids Source Classification Cancer	Drug Metabolite Endogenous Metabolite
4-Hydroxyestradiol (4-Hydroxy-17β-estradiol) is an endogenous metabolite of Estradiol (HY-B0141). 4-Hydroxyestradiol is carcinogenic and shows mutagenic activity in breast epithelial cells. 4-Hydroxyestradiol inhibits the binding of Estradiol to the estrogen receptor in a competitive manner, with a K_i of 0.48 nM .

HY-W091541

4-Hydroxy-1H-indole-3-carbaldehyde 4-hydroxyindole-3-carboxaldehyde	Alkaloids Monophenols Classification of Application Fields Capparis spinosa L. Other Diseases Phenols Capparidaceae Plants Disease Research Fields Indole Alkaloids Source Classification	Endogenous Metabolite
4-Hydroxy-1H-indole-3-carbaldehyde (4-Hydroxyindole-3-carboxaldehyde) is a plant metabolite. 4-Hydroxy-1H-indole-3-carbaldehyde can be isolated from Capparis spinosa L. 4-Hydroxy-1H-indole-3-carbaldehyde can be used in the synthesis of fluorescent probe. 4-Hydroxy-1H-indole-3-carbaldehyde can be used in the study of inflammation-related diseases .

HY-W015823

4-Hydroxybenzyl cyanide	Structural Classification Monophenols Classification of Application Fields Phenols Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
4-Hydroxybenzyl cyanide is an aromatic nitrile compound and also a precursor for tyramine synthesis. 4-Hydroxybenzyl cyanide exhibits strong antioxidant activity .

HY-W001084

Methyl 4-hydroxyphenylacetate	Structural Classification Monophenols Microorganisms Classification of Application Fields Other Diseases Phenols Disease Research Fields Source Classification	Others
Methyl 4-hydroxyphenylacetate is a compound found in the marine fungus Penicillium oxalicum 0312F1. Methyl 4-hydroxyphenylacetate can be Methyl 4-hydroxyphenylacetate inhibits replication of tobacco mosaic virus (TMV) in Nicotiana tabacum leaf discs. Methyl 4-hydroxyphenylacetate shows inhibitory activity against proliferation of cancer cells. Methyl 4-hydroxyphenylacetate can be used for the researches of TMV infection and cancer .

HY-W004078

4-Hydroxybenzylamine	Monophenols other families Classification of Application Fields Phenols Metabolic Disease Plants Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
4-Hydroxybenzylamine is a natural biogenic amine. 4-Hydroxybenzylamine can be produced through the breakdown metabolism of glucosinolates, with glutamine serving as the non-classical ammonia donor. 4-Hydroxybenzylamine can be utilized for the study of plant amine biosynthesis .

HY-W009300

4-Hydroxyestrone 1 Publications Verification 4-OHE1	Structural Classification Animals Neurological Disease Classification of Application Fields Endogenous metabolite Disease Research Fields Steroids Source Classification	Endogenous Metabolite Estrogen Receptor/ERR Sirtuin MDM-2/p53 PDI Ferroptosis Reactive Oxygen Species (ROS)
4-Hydroxyestrone (4-OHE1) is a brain-penetrant estrogen metabolite. 4-Hydroxyestrone shows neuroprotective effects involving increased cytoplasmic localization of p53 resulting from SIRT1-mediated p53 deacetylation. 4-Hydroxyestrone relies on PDI to mediate its protective effect against chemically induced ferroptosis in estrogen receptor-negative cancer cells. 4-Hydroxyestrone inhibits lipid peroxidation and lipid-ROS accumulation. 4-Hydroxyestrone blocks preovulatory luteinizing hormone surges in Rattus norvegicus. 4-Hydroxyestrone can be used for the researches of neurodegeneration, breast cancer and endocrine disease .

HY-W015675

4-Hydroxycyclohexanecarboxylic acid	Classification of Application Fields Ketones, Aldehydes, Acids Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
4-Hydroxycyclohexanecarboxylic acid belongs to the class of organic compounds known as cyclohexanols.

HY-Y0264R

4-Hydroxybenzoic acid (Standard)	Structural Classification Human Gut Microbiota Metabolites Monophenols Microorganisms Leguminosae Ketones, Aldehydes, Acids Phenols Plants Endogenous metabolite Glycyrrhiza uralensis Fisch. Source Classification	Reference Standards Endogenous Metabolite Bacterial
4-Hydroxybenzoic acid (Standard) is the analytical standard of 4-Hydroxybenzoic acid. This product is intended for research and analytical applications. 4-Hydroxybenzoic acid, a phenolic derivative of benzoic acid, could inhibit most gram-positive and some gram-negative bacteria, with an IC50 of 160 μg/mL.

HY-N0349R

Methyl paraben (Standard) Methyl 4-hydroxybenzoate (Standard)	Structural Classification Tsuga dumosa Monophenols Animals Pinaceae Phenols Plants Endogenous metabolite Source Classification	Reference Standards Bacterial Endogenous Metabolite
Methyl paraben (Standard) is the analytical standard of Methyl paraben. This product is intended for research and analytical applications. Methyl Paraben is a standardized methyl paraben allergen isolated from Yunnan hemlock (Tsuga dumosa). Methyl Paraben is commonly used as a stable, non-volatile preservative. Methyl Paraben increases histamine release and cellular regulation of immunity, blocks sodium channels, and prevents ischemia-reperfusion injury .

HY-N2026A

Propylparaben sodium 1 Publications Verification Propyl parahydroxybenzoate sodium; Propyl 4-hydroxybenzoate sodium	Infection Structural Classification 天然物 Classification of Application Fields Cosmetic Research Endogenous metabolite Disease Research Fields Source Classification	Estrogen Receptor/ERR Bacterial Sodium Channel PI3K JNK Akt Apoptosis
Propylparaben (Propyl parahydroxybenzoate) sodium is an antibacterial preservative that can be produced by plants and bacteria. Propylparaben sodium is an orally active weak estrogen receptor agonist. Propylparaben sodium regulates the PI3K-AKT and JNK signaling pathways, and induces oxidative stress. Propylparaben sodium is commonly used in cosmetics, pharmaceuticals and foods, and can be used in studies related to ovarian aging and myocardial ischemia-reperfusion injury .

HY-W051287

4-Hydroxy-2-butanone	天然物 Cucurbitaceae Plants Source Classification Benincasa hispida (Thunb.) Cogn.	Endogenous Metabolite
4-Hydroxy-2-butanone is a free volatile component of glycoside precursors in wax gourd .

HY-76632

4-Hydroxyisophthalic acid	Apocynaceae Ketones, Aldehydes, Acids Plants Decalepis hamiltonii Wight & Arn. Source Classification	Cholinesterase (ChE) SOD
4-Hydroxyisophthalic acid activates antioxidant enzymes (such as catalase CAT and superoxide dismutase SOD), scavenges free radicals, and exhibits antioxidant property. 4-Hydroxyisophthalic acid activates AChE and BChE, enhances neuronal function and improves Tau-induced neurobehavioral defects. 4-Hydroxyisophthalic acid improves the cognitive defects, and ameliorates circadian rhythm disorders of fruit flies .

HY-N6856R

4-Hydroxycoumarin (Standard)	Structural Classification Coumarins Phenylpropanoids Endogenous metabolite Source Classification	Reference Standards Bacterial Endogenous Metabolite
4-Hydroxycoumarin (Standard) is the analytical standard of 4-Hydroxycoumarin. This product is intended for research and analytical applications. 4-Hydroxycoumarin is an orally active coumarin derivative, one of the most versatile heterocyclic scaffolds, often used in the synthesis of various organic compounds. 4-Hydroxycoumarin possesses both electrophilic and nucleophilic properties. 4-Hydroxycoumarin is an HIV protease inhibitor and tyrosine kinase inhibitor. 4-Hydroxycoumarin has anti-inflammatory, antibacterial and anti-tumor effects .

HY-N1902R

4-Hydroxyphenylacetic acid (Standard)	Structural Classification Human Gut Microbiota Metabolites Monophenols Phenols Plants Compositae Endogenous metabolite Erythrina latissima E. Mey. Source Classification	Reference Standards Keap1-Nrf2 Endogenous Metabolite
4-Hydroxyphenylacetic acid (Standard) is the analytical standard of 4-Hydroxyphenylacetic acid. This product is intended for research and analytical applications. 4-hydroxyphenylacetic acid, a major microbiota-derived metabolite of polyphenols, is involved in the antioxidative action. 4-hydroxyphenylacetic acid induces expression of Nrf2 . IC₅₀ & Target:Nrf2 In Vivo: 4-Hydroxyphenylacetic acid (6, 12, or 25 mg/kg) increases Nrf2 translocation to the nucleus and enhances the activity of phase II and antioxidant enzymes. The protein levels of nuclear Nrf2 are increased by 170% and 230% in pre-treated 12 and 25 mg/kg 4-Hydroxyphenylacetic acid groups, respectively, compared with the control group.The 4-Hydroxyphenylacetic acid pretreatment at a final dose of 25 mg/kg markedly and selectively up-regulated the target genes of phase II enzymes and resulted in higher up-regulation than that of the control group by 270%, 400%, and 500% or UGT1A1, UGT1A9, and SULT2A1, respectively. 4-Hydroxyphenylacetic acid also suppresses the expression of CYP2E1 .

HY-W010040R

4-Hydroxyphenylpyruvic acid (Standard)	Structural Classification Monophenols Ketones, Aldehydes, Acids Disease markers Phenols Endocrine diseases Nervous System Disorder Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite
4-Hydroxyphenylpyruvic acid (Standard) is the analytical standard of 4-Hydroxyphenylpyruvic acid (HY-W010040). This product is intended for research and analytical applications. 4-Hydroxyphenylpyruvic acid is an intermediate in the metabolism of the amino acid phenylalanine. 4-Hydroxyphenylpyruvic acid is a substrate of 4-hydroxyphenylpyruvic acid dioxygenase (HPPA). 4-Hydroxyphenylpyruvic acid can be used in the study of HPD-related diseases, such as type III tyrosinemia and hawkinsinuria .

HY-107164

Thiomarinol A 4-hydroxythiomarinol C	Infection Microorganisms Classification of Application Fields Antibiotics Antibacterial Disease Research Disease Research Fields Other Antibiotics Source Classification	Antibiotic Bacterial
Thiomarinol A (4-Hydroxythiomarinol C) is a potent antibiotic. Thiomarinol A is a hybrid of dithiolopyrrolone and marinolic acid. Thiomarinol A shows antimicrobial activity. Thiomarinol A inhibits MRSA IleRS in a dose-dependent with a K_i ^app value of 19 nM .

HY-N2269

p-Hydroxyphenethyl anisate 4-hydroxyphenethyl anisate	Structural Classification Monophenols Classification of Application Fields Phenols Metabolic Disease Kleinia odora (Forssk.) DC. Umbelliferae Plants Disease Research Fields Source Classification	Others
p-Hydroxyphenethyl anisate is a main constituent of Notopterygium Radix . p-Hydroxyphenethyl anisate can be used as a new type of natural sustained-release excipients .

HY-N2026R

Propylparaben (Standard) Propyl parahydroxybenzoate (Standard); Propyl 4-hydroxybenzoate (Standard)	Structural Classification 天然物 Monophenols Phenols Endogenous metabolite Source Classification	Reference Standards Bacterial Apoptosis Estrogen Receptor/ERR Sodium Channel PI3K JNK Akt
Propylparaben (Propyl parahydroxybenzoate) (Standard) is the analytical standard of Propylparaben (HY-N2026). Propylparaben (Propyl parahydroxybenzoate) is an antibacterial preservative that can be produced by plants and bacteria. Propylparaben is an orally active weak estrogen receptor agonist. Propylparaben regulates the PI3K-AKT and JNK signaling pathways, and induces oxidative stress. Propylparaben is commonly used in cosmetics, pharmaceuticals and foods, and can be used in studies related to ovarian aging and myocardial ischemia-reperfusion injury .

HY-B0934R

Ethylparaben (Standard) Ethyl parahydroxybenzoate (Standard); Ethyl 4-hydroxybenzoate (Standard)	Monophenols Microorganisms Phenols Source Classification	Reference Standards Bacterial Fungal
Ethylparaben (Standard) is the analytical standard of Ethylparaben. This product is intended for research and analytical applications. Ethylparaben is the ethyl ester of paraben and is used as an antifungal preservative and food additive .

HY-B1431R

Butylparaben (Standard) Butyl parahydroxybenzoate (Standard); Butyl paraben (Standard); Butyl 4-hydroxybenzoate (Standard)	Monophenols Phenols Endogenous metabolite Source Classification	Reference Standards Bacterial Endogenous Metabolite DNA/RNA Synthesis
Butylparaben (Standard) is the analytical standard of Butylparaben. This product is intended for research and analytical applications. Butylparaben is an organic compound that has proven to be a very successful antimicrobial preservative in cosmetics, can also be used in active molecule suspensions, and as a food flavoring additive .

HY-Y0892R

4-Hydroxybenzyl alcohol (Standard)	Structural Classification Human Gut Microbiota Metabolites Monophenols Microorganisms Gastrodia elata Bl. Orchidaceae Phenols Plants Endogenous metabolite Source Classification	Reference Standards Apoptosis Endogenous Metabolite
4-Hydroxybenzyl alcohol (Standard) is the analytical standard of 4-Hydroxybenzyl alcohol. This product is intended for research and analytical applications. 4-Hydroxybenzyl alcohol is a phenolic compound widely distributed in various kinds of plants. Anti-inflammatory, anti-oxidant, anti-nociceptive activity. Neuroprotective effect. Inhibitor of tumor angiogenesis and growth [4].

HY-W002587

4-Hydroxy-3-methylbenzoic acid	Monophenols Classification of Application Fields Ketones, Aldehydes, Acids Other Diseases Phenols Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
4-Hydroxy-3-methylbenzoic acid is a normal organic acid identified in urine specimens from a healthy population.

HY-W001084R

Methyl 4-hydroxyphenylacetate (Standard)	Structural Classification Monophenols Microorganisms Phenols Source Classification	Reference Standards
Methyl 4-hydroxyphenylacetate (Standard) is the analytical standard of Methyl 4-hydroxyphenylacetate (HY-W001084). This product is intended for research and analytical applications. Methyl 4-hydroxyphenylacetate is a compound found in the marine fungus Penicillium oxalicum 0312F1. Methyl 4-hydroxyphenylacetate can be Methyl 4-hydroxyphenylacetate inhibits replication of tobacco mosaic virus (TMV) in Nicotiana tabacum leaf discs. Methyl 4-hydroxyphenylacetate shows inhibitory activity against proliferation of cancer cells. Methyl 4-hydroxyphenylacetate can be used for the researches of TMV infection and cancer .

HY-33914

4-Hydroxymethylpyrazole	天然物 Classification of Application Fields Other Diseases Endogenous metabolite Disease Research Fields Source Classification	Drug Metabolite
4-Hydroxymethylpyrazole is the primary metabolite of Fomepizole (HY-B0876) produced through hepatic oxidative metabolism. 4-Hydroxymethylpyrazole exhibits a plasma concentration that is positively correlated with the administered dosage of Fomepizole, and it demonstrates a relatively short half-life. 4-Hydroxymethylpyrazole demonstrates inhibitory effects on alcohol dehydrogenase (ADH) in both humans and monkeys, but its inhibition constant is significantly higher than that of Fomepizole, rendering its in vivo impact negligible .

HY-N16394

4-Hydroxyscytalone	Structural Classification 天然物 Microorganisms Source Classification	Endogenous Metabolite
4-Hydroxyscytalone (Compound 3) is a microbial secondary metabolite. 4-Hydroxyscytalone can be isolated from the oak fungus Diplodia corticola. 4-Hydroxyscytalone has toxicity against Artemia salina with a LC50 of 90.6 μ/mL, but no significant antifungal activity. 4-Hydroxyscytalone can be used for cancer therapy research .

HY-W098556

4-Hydroxyhygric acid	Infection Alkaloids other families Pyrrole Alkaloids Classification of Application Fields Plants Disease Research Fields Source Classification	Insecticide
4-Hydroxyhygric acid is a compound isolated from leaves of five species of the leguminous tropical tree Copuiferq. 4-Hydroxyhygric acid is the inhibitor of larval development of the seed-feeding bruchid beetle Callosobruchus maculatus and to have significant feeding deterrence of the leaf-feeding lepidopteran Spodoprera littoralis .

HY-W794132

4-Hydroxy-9h-xanthen-9-one	Structural Classification Xanthones Securidaca inappendiculata Hassk. Polygalaceae Phenols Plants Source Classification	Drug Intermediate
4-Hydroxy-9h-xanthen-9-one is a natural product .

Species:	Human (2)
Tag:	His (2)
Source:	HEK293 (1) E. coli (1)

製品番号	Compare	製品名	Species	Source	Image

HY-P70024

	HPD/HPPDase Protein, Human (His) rHu4-hydroxyphenylpyruvate dioxygenase /HPD, His; 4-hydroxyphenylpyruvate Dioxygenase; 4-hydroxyphenylpyruvic Acid Oxidase; 4HPPD; HPD; HPPDase; HPD; PPD	Human	E. coli
	HPD is a key enzyme in tyrosine catabolism and plays a key role in catalyzing the conversion of 4-hydroxyphenylpyruvate into homogentisate. This enzymatic process represents a key step in the tyrosine metabolic pathway and contributes to the breakdown of this amino acid. HPD/HPPDase Protein, Human (His) is the recombinant human-derived HPD/HPPDase protein, expressed by E. coli , with N-6*His labeled tag.

HY-P71087

	P4HB Protein, Human (HEK293, His) Protein Disulfide-Isomerase; PDI; Cellular Thyroid Hormone-Binding Protein; Prolyl 4-hydroxylase Subunit Beta; p55; P4HB; ERBA2L; PDI; PDIA1; PO4DB	Human	HEK293
	The P4HB protein is a multifunctional entity that catalyzes disulfide bonding processes at the cell surface and within cells. As a reductase, it modifies outer surface proteins and participates in the formation of disulfide bonds in nascent proteins. P4HB Protein, Human (HEK293, His) is the recombinant human-derived P4HB protein, expressed by HEK293 , with C-6*His labeled tag.

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Source
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製品番号	製品名	構造式

HY-15550S

4'-Hydroxy diclofenac-d4
4'-Hydroxy diclofenac-d₄ is the deuterium labeled 4'-Hydroxy diclofenac. 4'-Hydroxy diclofenac is an orally active metabolite of Diclofenac (HY-15036) by cytochrome P450 2C9 (CYP2C9). 4'-Hydroxy diclofenac has anti-inflammatory and analgesic properties .

HY-W008772S

4-Hydroxymephenytoin-d3
4-Hydroxymephenytoin-d₃ is the deuterium labeled 4-Hydroxymephenytoin. 4-Hydroxymephenytoin is a metabolism of an antiepileptic agent mephenytoin, which is used as a CYP2C19 substrate .

HY-Y0264S1

4-Hydroxybenzoic acid-d4
4-Hydroxybenzoic acid-d₄ is the deuterium labeled 4-Hydroxybenzoic acid. 4-Hydroxybenzoic acid, a phenolic derivative of benzoic acid, could inhibit most gram-positive and some gram-negative bacteria, with an IC50 of 160 μg/mL.

HY-113466S

4-Hydroxynonenal-d3

4-Hydroxynonenal-d₃ is the deuterium labeled 4-Hydroxynonenal. 4-Hydroxynonenal (4-HNE) is an α,β unsaturated hydroxyalkenal and an oxidative/nitrosative stress biomarker. 4-Hydroxynonenal is a substrate and an inhibitor of acetaldehyde dehydrogenase 2 (ALDH2). 4-Hydroxynonenal can modulate a number of signaling processes mainly through forming covalent adducts with nucleophilic functional groups in proteins, nucleic acids, and membrane lipids. 4-Hydroxynonenal plays an important role in cancer through mitochondria .

HY-N2026S1

Propylparaben-d4

Propylparaben-d₄ (Propyl parahydroxybenzoate-d4) is the deuterium labeled Propylparaben (HY-N2026). Propylparaben (Propyl parahydroxybenzoate) is an antibacterial preservative that can be produced by plants and bacteria. Propylparaben is an orally active weak estrogen receptor agonist. Propylparaben regulates the PI3K-AKT and JNK signaling pathways, and induces oxidative stress. Propylparaben is commonly used in cosmetics, pharmaceuticals and foods, and can be used in studies related to ovarian aging and myocardial ischemia-reperfusion injury .

HY-Y0264S

4-Hydroxybenzoic acid-13C6
4-Hydroxybenzoic acid- ¹³C6 is the ¹³C labeled isotope of 4-Hydroxybenzoic acid- ¹³C6.4-Hydroxybenzoic acid is a phenolic derivative of benzoic acid, which can inhibit most Gram-positive bacteria and some Gram-negative bacteria with an IC50 value of 160 μg/mL.

HY-100641S

4-Hydroxytolbutamide-d9
4-Hydroxytolbutamide-d₉ is the deuterium labeled 4-Hydroxytolbutamide. 4-Hydroxytolbutamide (Hydroxytolbutamide) is a metabolite of Tolbutamide. 4-Hydroxytolbutamide is metabolized by CYP2C8 and CYP2C9. Tolbutamide is a first generation potassium channel blocker and a sulfonylurea oral antidiabetic .

HY-W005288S

4-Vinylphenol-d4
4-Vinylphenol-d₄ is deuterated labeled 4-Vinylphenol (HY-W005288). 4-Vinylphenol is found in the medicinal herb Hedyotis diffusa Willd, wild rice and is also the metabolite of p-coumaric and ferulic acid by lactic acid bacteria in wine. 4-Vinylphenol induces apoptosis and inhibits blood vessels formation and suppresses invasive breast tumor growth in vivo .

HY-B1431S

Butylparaben-d4
Butylparaben-d₄ is the deuterium labeled Butylparaben. Butylparaben is an organic compound, has proven to be a highly successful antimicrobial preservative in cosmetics, also used in medication suspensions, and as a flavoring additive in food.

HY-66005S2

Acetaminophen-d7
Acetaminophen-d₇ is the deuterium labeled Acetaminophen. Acetaminophen (Paracetamol) is a selective cyclooxygenase-2 (COX-2) inhibitor with an IC50 of 25.8 μM; is a widely used antipyretic and analgesic agent. Acetaminophen is a potent hepatic N-acetyltransferase 2 (NAT2) inhibitor.

HY-N1902S

4-Hydroxyphenylacetic acid-d6
4-Hydroxyphenylacetic acid-d₆ is the deuterium labeled 4-Hydroxyphenylacetic acid. 4-hydroxyphenylacetic acid, a major microbiota-derived metabolite of polyphenols, is involved in the antioxidative action. 4-hydroxyphenylacetic acid induces expression of Nrf2 .

HY-Y0264S2

4-Hydroxybenzoic acid-13c
4-Hydroxybenzoic acid- ¹³C is the ¹³C labeled 4-Hydroxybenzoic acid . 4-Hydroxybenzoic acid, a phenolic derivative of benzoic acid, could inhibit most gram-positive and some gram-negative bacteria, with an IC₅₀ of 160 μg/mL .

HY-B0934S

Ethylparaben-d4
Ethylparaben-d₄ is the deuterium labeled Ethylparaben .

HY-N0349S1

Methyl paraben-13C6

Methyl Paraben- ¹³C₆ (Methyl 4-hydroxybenzoate- ¹³C₆) is a ¹³C labeled Methyl Paraben (HY-N0349) . Methyl Paraben, isolated from the barks of Tsuga dumosa the methyl ester of p-hydroxybenzoic acid, is a standardized chemical allergen. Methyl Paraben is a stable, non-volatile compound used as an antimicrobial preservative in foods, agents and cosmetics. The physiologic effect of Methyl Paraben is by means of increased histamine release, and cell-mediated immunity .

HY-132436S

4’-Hydroxy Flurbiprofen-d3
4’-Hydroxy Flurbiprofen-d₃ is the deuterium labeled 4’-Hydroxy Flurbiprofen .

HY-W014937S1

4-Hydroxybenzophenone-d5
4-Hydroxybenzophenone-d₅ is the deuterium labeled 4-Hydroxybenzophenone .

HY-N1902S1

4-Hydroxyphenylacetic acid-d4
4-Hydroxyphenylacetic acid-d₄ is the deuterium labeled 4-Hydroxyphenylacetic acid . 4-hydroxyphenylacetic acid, a major microbiota-derived metabolite of polyphenols, is involved in the antioxidative action. 4-hydroxyphenylacetic acid induces expression of Nrf2 .

HY-W013482S

Benzyl 4-hydroxybenzoate-d4
Benzyl 4-hydroxybenzoate-d₄ is the deuterium labeled Benzyl 4-hydroxybenzoate .

HY-W015026S

Isobutylparaben-d4
Isobutylparaben-d₄ is the deuterium labeled Isobutylparaben. Isobutylparaben (Isobutyl 4-hydroxybenzoate) is the agonist for PXR, CAR and PPAR. Isobutylparaben has a broad-spectrum antimicrobial activity and widely used in personal care products and cosmetics .

HY-100561S

Tempol-d17,15N
Tempol-d₁₇, ¹⁵N is the deuterium labeled Tempol . Tempol is a general superoxide dismutase (SOD)-mimetic agent that efficiently neutralizes reactive oxygen species (ROS) .

HY-B1431S1

Butylparaben-13C6
Butylparaben- ¹³C₆ is the ¹³C labeled Butylparaben . Butylparaben is an organic compound, has proven to be a highly successful antimicrobial preservative in cosmetics, also used in medication suspensions, and as a flavoring additive in food.

HY-W653994

Ethyl Paraben-13C6
Ethyl Paraben- ¹³C₆ (Ethyl parahydroxybenzoate- ¹³C₆) is ¹³C labeled Ethylparaben. Ethylparaben is the ethyl ester of paraben and is used as an antifungal preservative and food additive .

HY-W654020

Propyl paraben-13C6

Propyl paraben- ¹³C₆ (Propyl parahydroxybenzoate- ¹³C₆) is ¹³C labeled Propylparaben. Propylparaben (Propyl parahydroxybenzoate) is an antibacterial preservative that can be produced by plants and bacteria. Propylparaben is commonly used in cosmetics, pharmaceuticals and foods. Propylparaben disrupts follicular growth and steroidogenic function by altering cell cycle, apoptosis and steroidogenic pathways. Propylparaben also reduced sperm count and motility in rats .

HY-12767S

4-Hydroxyphenyl Carvedilol-d5
4-Hydroxyphenyl Carvedilol-d₅ is the deuterium labeled 4-Hydroxyphenyl Carvedilol.

HY-143816S

4-Hydroxy Atorvastatin-d5 hemicalcium
4-Hydroxy Atorvastatin-d₅ (calcium) is the deuterium labeled 4-Hydroxy Atorvastatin calcium .

HY-W150903S

N-Heptyl 4-hydroxybenzoate-d4
N-Heptyl 4-hydroxybenzoate-d₄ is the deuterium labeled N-Heptyl 4-hydroxybenzoate (HY-W150903) . N-Heptyl 4-hydroxybenzoate (p-Oxybenzoesaureheptylester) is an antimicrobial agent that inhibits S. aureus with MIC of 12.5 μg/mL. N-Heptyl 4-hydroxybenzoate also against plant pathogenic fungi, such as Alternaria brassicicola, F. solani, C. dematium and C. acutatum .

HY-Y1042S

4-Cyanophenol-d4
4-Cyanophenol-d₄ is the deuterium labeled 4-Cyanophenol .

HY-N0349S

Methyl paraben-d4

Methyl paraben-d₄ is the deuterium labeled Methyl Paraben . Methyl Paraben, isolated from the barks of Tsuga dumosa the methyl ester of p-hydroxybenzoic acid, is a standardized chemical allergen. Methyl Paraben is a stable, non-volatile compound used as an antimicrobial preservative in foods, agents and cosmetics. The physiologic effect of Methyl Paraben is by means of increased histamine release, and cell-mediated immunity .

HY-12767S1

Carvedilol metabolite 4-Hydroxyphenyl Carvedilol-d4
Carvedilol metabolite 4-Hydroxyphenyl Carvedilol-d₄ is deuterated labeled Carvedilol metabolite 4-Hydroxyphenyl Carvedilol (HY-12767). 4-Hydroxyphenyl Carvedilol is a metabolite of Carvedilol.

HY-B2150S

4-Hydroxyantipyrine-d3
4-Hydroxyantipyrine-d₃ is the deuterium labeled 4-Hydroxyantipyrine. 4-Hydroxyantipyrine is the major metabolite of Antipyrine, can be as a biodistribution promoter. 4-Hydroxyantipyrine can increase distribution of concentration ratio of Antipyrine in the brain .

HY-W150053S

N-Octyl 4-hydroxybenzoate-d4
N-Octyl 4-hydroxybenzoate-d₄ is the deuterium labeled N-Octyl 4-hydroxybenzoate .

HY-115354S

4-Hydroxy Alprazolam-d5
4-Hydroxy Alprazolam-d5 (4-Hydroxyalprazolam-d5; RS-4-Hydroxyalprazolam-d5) is the deuterium labeled 4-hydroxy Alprazolam (HY-115354) .

HY-100634SA

4-Hydroxypropranolol-d7

4-Hydroxypropranolol-d₇ is the deuterium labeled 4-Hydroxypropranolol hydrochloride. 4-Hydroxypropranolol hydrochlorid is an active metabolite of Propranolol. 4-Hydroxypropranolol hydrochlorid is of comparable potency to Propranolol. 4-Hydroxypropranolol hydrochlorid inhibits β1- and β2-adrenergic receptors with pA2 values of 8.24 and 8.26, respectively. 4-Hydroxypropranolol hydrochlorid has intrinsic sympathomimetic activity, membrane stabilizing activity and potent antioxidant properties .

HY-100634S

4-Hydroxypropranolol-d7 hydrochloride

4-Hydroxypropranolol-d₇ (hydrochloride) is a deuterium labeled 4-Hydroxypropranolol hydrochloride. 4-Hydroxypropranolol hydrochlorid is an active metabolite of Propranolol, with potency comparable to Propranolol. 4-Hydroxypropranolol hydrochlorid inhibits β1- and β2-adrenergic receptors with pA2 values of 8.24 and 8.26, respectively. 4-Hydroxypropranolol hydrochlorid has intrinsic sympathomimetic activity, membrane stabilizing activity and potent antioxidant properties .

HY-133116S

4-Hydroxyatomoxetine-d3
4-Hydroxyatomoxetine-d₃ is a deuterium labeled 4-Hydroxyatomoxetine. 4-Hydroxyatomoxetine is an active metabolite of Atomoxetine (Tomoxetine). 4-Hydroxyatomoxetine is metabolized by the enzyme cytochrome P450 2D6 (CYP2D6). Atomoxetine is a potent and selective noradrenal in re-uptake inhibitor .

HY-W701834S

4-Hydroxymethylambrisentan-d5
4-Hydroxymethylambrisentan-d₅ is deuterium-labeled 4-Hydroxymethylambrisentan (HY-W701834) .

HY-W738939

4-Hydroxybenzhydrazide-d4
4-Hydroxybenzhydrazide-d₄ is the deuterium labeled 4-Hydroxybenzohydrazide (HY-W012579).

HY-W714025S

4-Hydroxychlorpropham-d7
4-Hydroxychlorpropham-d₇ is the deuterium labeled Isopropyl (3-chloro-4-hydroxyphenyl)carbamate (HY-W714025).

HY-W743678

4-Hydroxymelatonin-d4
4-Hydroxymelatonin-d₄ is the deuterium labeled N-[2-(4-Hydroxy-5-methoxy-1H-indol-3-yl)ethyl]acetamide (HY-W587926).

HY-W740777

4-Hydroxyphenylbutazone-d9
4-Hydroxyphenylbutazone-d₉ is the deuterium labeled 4-Hydroxyphenylbutazone (HY-139199). 4-Hydroxyphenylbutazone is a metabolite of Phenylbutazone. Phenylbutazone, a nonsteroidal anti-inflammatory agent (NSAID), is an efficient reducing cofactor for the peroxidase activity of prostaglandin H synthase (PHS) .

HY-132423S

4-Hydroxy Clonidine-d4
4-Hydroxy Clonidine-d₄ is the deuterium labeled 4-Hydroxy Clonidine .

HY-143772S

4-Hydroxy Aceclofenac-d4
4-Hydroxy Aceclofenac-d₄ is the deuterium labeled 4-Hydroxy Aceclofenac .

HY-124355S

4-Hydroxy hexenal-d3
4-Hydroxy hexenal-d₃ is the deuterium labeled 4-Hydroxy hexenal .

HY-132439S

4-Hydroxy Mepivacaine-d3
4-Hydroxy Mepivacaine-d₃ is the deuterium labeled 4-Hydroxy Mepivacaine .

HY-Y0162S

4-Hydroxy biphenyl-d5
4-Hydroxy biphenyl-d₅ is deuterium labeled [1,1'-Biphenyl]-4-ol.

HY-W717661

4-Hydroxyphenyl diphenyl phosphate-d10
4-Hydroxyphenyl diphenyl phosphate-d10 is the deuterium labeled 4-Hydroxyphenyl diphenyl phosphate-d10 (HY-W717661) .

HY-W009300S

4-Hydroxyestrone-d4

4-Hydroxyestrone (4-OHE1)-d₄ is the deuterium labeled 4-Hydroxyestrone (HY-W009300). 4-Hydroxyestrone is a brain-penetrant estrogen metabolite. 4-Hydroxyestrone shows neuroprotective effects involving increased cytoplasmic localization of p53 resulting from SIRT1-mediated p53 deacetylation. 4-Hydroxyestrone relies on PDI to mediate its protective effect against chemically induced ferroptosis in estrogen receptor-negative cancer cells. 4-Hydroxyestrone inhibits lipid peroxidation and lipid-ROS accumulation. 4-Hydroxyestrone blocks preovulatory luteinizing hormone surges in Rattus norvegicus. 4-Hydroxyestrone can be used for the researches of neurodegeneration, breast cancer and endocrine disease .

HY-155842S

4-Hydroxy AtorvastatinAtorvastatin-d5 hemicalcium
4-Hydroxy AtorvastatinAtorvastatin-d₅ hemicalcium is deuterated labeled 4-Hydroxy AtorvastatinAtorvastatin.

HY-143017S

4-Hydroxy Atorvastatin-d5 disodium
4-Hydroxy Atorvastatin-d₅ (disodium) is the deuterium labeled 4-Hydroxy Atorvastatin disodium salt .

HY-W740139

4-Hydroxy midazolam methanoate-d5
4-Hydroxy midazolam methanoate-d₅ is the deuterium labeled 4-Hydroxymidazolam (HY-100050). 4-Hydroxymidazolam is a major metabolite of Midazolam. Midazolam is a potent benzodiazepine with anxiolytic properties.

Host:	Mouse (2) Rabbit (5)
Reactivity:	Human (6) Rat (3) Mouse (3) Species independent (1)
Application:	IHC-P (4) ICC/IF (2) mIHC (1) IF-Tissue (1) IP (2) WB (5) FC (1)
Isotype:	IgG (5) IgG1 (2)
Conjugation:	Non-conjugated (7)
Clonality:	Polyclonal (1) Monoclonal (3) Recombinant (2)
Modification:	Unmodified (4)

製品番号	Compare	製品名	Application	Reactivity	Image

HY-P81208

	4 Hydroxynonenal Antibody 10+ Cited Publications 4-hydroxy-2-Nonenal; 4hydroxynonenal; 4-hydroxynonenal; HNE; 4HNE; 4-HNE; (E)-4-hydroxy-2-nonenal; 2-Nonenal, 4-hydroxy-, (2E)-; (2E)-4-hydroxy-2-nonenal; 4-hydroxy-2(E)-nonenal	WB, IHC-P, IF-Tissue, mIHC	Species independent
	4 Hydroxynonenal Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to 4 Hydroxynonenal.

HY-P88144

	P4HA3 Antibody (YA7828) 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase); alpha III subunit; alpha polypeptide III; C-P4H alpha III; collagen prolyl 4-hydroxylase alpha(III); procollagen-proline; prolyl 4-hydroxylase	IHC-P	Human, Mouse, Rat
	P4HA3 Antibody (YA7828) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to P4HA3.

HY-P88144A

	P4HA3 Antibody (YA7828)(PBS only) 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase); alpha III subunit; alpha polypeptide III; C-P4H alpha III; collagen prolyl 4-hydroxylase alpha(III); procollagen-proline; prolyl 4-hydroxylase	IHC-P	Human, Mouse, Rat
	P4HA3 Antibody (YA7828) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to P4HA3.

HY-P811259

	P4HA1 Antibody P4HA, P4HA1, Prolyl 4-hydroxylase subunit alpha-1, 4-PH alpha-1	WB, ICC/IF	Human, Mouse, Rat
	P4HA1 Antibody is a Rabbit-derived and non-conjugated IgG Polyclonal antibody, targeting to P4HA1.

HY-P83297

	HPDL Antibody (YA3042) 4-hydroxyphenylpyruvate dioxygenase like; GLOXD1; 4-HPPD-L	WB, IP	Human
	HPDL Antibody (YA3042) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to HPDL.

HY-P83297A

	HPDL Antibody (YA3042)(PBS only) 4-hydroxyphenylpyruvate dioxygenase like; GLOXD1; 4-HPPD-L	WB, IP	Human
	HPDL Antibody (YA3042) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to HPDL.

HY-P83639

	Cytochrome P450 2D6 Antibody (YA3384) CYP2D6; CYP2DL1; Cytochrome P450 2D6; CYPIID6; Cytochrome P450-DB1; Debrisoquine 4-hydroxylase	WB, IHC-P, ICC/IF, FC	Human
	Cytochrome P450 2D6 Antibody (YA3384) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Cytochrome P450 2D6.

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製品番号	製品名		Classification

HY-113803

4-Hydroxynonenal alkyne 4-HNE alkyne		Alkynes
4-Hydroxynonenal alkyne (4-HNE alkyne) is a click chemical reagent containing alkynes. 4-Hydroxynonenal alkyne induces heme oxygenase and cell apoptosis in colon cancer (RKO) cells .

製品番号	製品名		Classification

HY-B1431

Butylparaben 2 Publications Verification Butyl parahydroxybenzoate; Butyl paraben; Butyl 4-hydroxybenzoate		Sweetening Agents
Butylparaben is an organic compound that has proven to be a very successful antimicrobial preservative in cosmetics, can also be used in active molecule suspensions, and as a food flavoring additive .

HY-W013482

Benzyl 4-hydroxybenzoate Benzyl Paraben		Preservatives
Benzyl 4-hydroxybenzoate is a prominent material. Benzyl 4-hydroxybenzoate can be used as an excipient, such as bacteriostatic agent, preservative. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs .

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