P4HA1 Antibody
(Synonyms: P4HA, P4HA1, Prolyl 4-hydroxylase subunit alpha-1, 4-PH alpha-1)P4HA1 Antibody is a Rabbit-derived and non-conjugated IgG Polyclonal antibody, targeting to P4HA1.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, ICC/IF
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Reactivity :
Human, Mouse, Rat
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Formulation:
Supplied in PBS (pH 7.4), containing 30% glycerol, and 0.01% sodium azide.
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Conjugation:
Non-conjugated
Applications
| Application |
WB
WB: Western Blot
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
|---|---|---|
| Dilution Ratio | 1:1000-2000 | 1:50-200 |
Product Details
P4HA1 Antibody is a Rabbit-derived and non-conjugated IgG Polyclonal antibody, targeting to P4HA1.
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Host Rabbit
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Clonality Polyclonal
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Species ReactivityHuman, Mouse, Rat
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Observed Molecular WeightObserved band size: 61 kDaNote: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 58; 60; 61 kDa
Purified recombinant protein of human P4HA1
Endogenous
affinity purified.
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in PBS (pH 7.4), containing 30% glycerol, and 0.01% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
P4HA1 catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins
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Subcellular Localization
Endoplasmic reticulum lumen
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Expression
Tissue_Specificity: Expressed in the heart, liver, skeletal muscle, kidney, placenta, lung and pancreas. -
Isoforms & Post-Translational Modification
P4HA1 has 3 isoforms, P13674-1: amino acid length is 534, molecular weight is 61049 Da (predicted); P13674-2: amino acid length is 534, molecular weight is 60967 Da (predicted); P13674-3: amino acid length is 516, molecular weight is 58958 Da (predicted).
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Subunit
Heterotetramer of two alpha-1 chains and two beta chains (P4HB)(the beta chain is the multi-functional PDI), where P4HB plays the role of a structural subunit; this tetramer catalyzes the formation of 4-hydroxyproline in collagen
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SwissProt ID
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Synonyms
P4HA, P4HA1, Prolyl 4-hydroxylase subunit alpha-1, 4-PH alpha-1
Documentation