Methyl paraben-d4
Methyl paraben-d4 is the deuterium labeled Methyl Paraben. Methyl Paraben, isolated from the barks of Tsuga dumosa the methyl ester of p-hydroxybenzoic acid, is a standardized chemical allergen. Methyl Paraben is a stable, non-volatile compound used as an antimicrobial preservative in foods, agents and cosmetics. The physiologic effect of Methyl Paraben is by means of increased histamine release, and cell-mediated immunity.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.55%
- CAS 番号: 362049-51-2
- 分子式: C8H4D4O3
- 分子量:156.17
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
Endogenous Metabolite アイソフォーム固有の製品をすべて表示
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生物活性
製品説明
体外実験
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
アプリケーション
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
化学情報
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CAS 番号 362049-51-2
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非標識Cas 99-76-3
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性状 Solid
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分子量 156.17
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分子式 C8H4D4O3
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Color White to off-white
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SMILES
O=C(OC)C1=C([2H])C([2H])=C(O)C([2H])=C1[2H]
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別名
Methyl 4-hydroxybenzoate-d4
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
体外:
DMSO : 100 mg/mL (640.33 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (273 KB)
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SDS (459 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
[2]. Soni MG, et al. Evaluation of the health aspects of methyl paraben: a review of the published literature. Food Chem Toxicol. 2002 Oct;40(10):1335-73. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 6.4033 mL | 32.0164 mL | 64.0328 mL | 160.0820 mL |
| 5 mM | 1.2807 mL | 6.4033 mL | 12.8066 mL | 32.0164 mL | |
| 10 mM | 0.6403 mL | 3.2016 mL | 6.4033 mL | 16.0082 mL | |
| 15 mM | 0.4269 mL | 2.1344 mL | 4.2689 mL | 10.6721 mL | |
| 20 mM | 0.3202 mL | 1.6008 mL | 3.2016 mL | 8.0041 mL | |
| 25 mM | 0.2561 mL | 1.2807 mL | 2.5613 mL | 6.4033 mL | |
| 30 mM | 0.2134 mL | 1.0672 mL | 2.1344 mL | 5.3361 mL | |
| 40 mM | 0.1601 mL | 0.8004 mL | 1.6008 mL | 4.0020 mL | |
| 50 mM | 0.1281 mL | 0.6403 mL | 1.2807 mL | 3.2016 mL | |
| 60 mM | 0.1067 mL | 0.5336 mL | 1.0672 mL | 2.6680 mL | |
| 80 mM | 0.0800 mL | 0.4002 mL | 0.8004 mL | 2.0010 mL | |
| 100 mM | 0.0640 mL | 0.3202 mL | 0.6403 mL | 1.6008 mL |
Methyl paraben-d4 関連分類
HY-N0349S 関連分類
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