99-76-3
99-76-3
Chemical Structure
Methyl paraben
Synonym(s): Methyl 4-hydroxybenzoate
- CAS No.: 99-76-3
- Formula:C8H8O3
- Molecular Weight:152.15
IUPAC Name: methyl 4-hydroxybenzoate
InChIKey: LXCFILQKKLGQFO-UHFFFAOYSA-N
SMILES: O=C(OC)C1=CC=C(O)C=C1
Biological Activity: Methyl Paraben is a standardized methyl paraben allergen isolated from Yunnan hemlock (Tsuga dumosa). Methyl Paraben is commonly used as a stable, non-volatile preservative. Methyl Paraben increases histamine release and cellular regulation of immunity, blocks sodium channels, and prevents ischemia-reperfusion injury[1][2][3][4].
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Methyl paraben | 99.86% | Methyl Paraben is a standardized methyl paraben allergen isolated from Yunnan hemlock (Tsuga dumosa). Methyl Paraben is commonly used as a stable, non-volatile preservative. Methyl Paraben increases histamine release and cellular regulation of immunity, blocks sodium channels, and prevents ischemia-reperfusion injury. | ||||||||||||||||||||
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Methyl paraben (Standard) | 99.99% | Methyl paraben (Standard) is the analytical standard of Methyl paraben. This product is intended for research and analytical applications. Methyl Paraben is a standardized methyl paraben allergen isolated from Yunnan hemlock (Tsuga dumosa). Methyl Paraben is commonly used as a stable, non-volatile preservative. Methyl Paraben increases histamine release and cellular regulation of immunity, blocks sodium channels, and prevents ischemia-reperfusion injury. | ||||||||||||||||||||
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Methyl paraben-d4 | Methyl paraben-d4 is the deuterium labeled Methyl Paraben. Methyl Paraben, isolated from the barks of Tsuga dumosa the methyl ester of p-hydroxybenzoic acid, is a standardized chemical allergen. Methyl Paraben is a stable, non-volatile compound used as an antimicrobial preservative in foods, agents and cosmetics. The physiologic effect of Methyl Paraben is by means of increased histamine release, and cell-mediated immunity. | |||||||||||||||||||||
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Methyl paraben-d3 | Methyl paraben-d3 (Methyl 4-hydroxybenzoate-d3) is the deuterium labeled Methyl paraben (HY-N0349). Methyl Paraben is a standardized methyl paraben allergen isolated from Yunnan hemlock (Tsuga dumosa). Methyl Paraben is commonly used as a stable, non-volatile preservative. Methyl Paraben increases histamine release and cellular regulation of immunity, blocks sodium channels, and prevents ischemia-reperfusion injury. | |||||||||||||||||||||
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Methyl Paraben-13C6 | Methyl Paraben-13C6 (Methyl 4-hydroxybenzoate-13C6) is a 13C labeled Methyl Paraben (HY-N0349). Methyl Paraben, isolated from the barks of Tsuga dumosa the methyl ester of p-hydroxybenzoic acid, is a standardized chemical allergen. Methyl Paraben is a stable, non-volatile compound used as an antimicrobial preservative in foods, agents and cosmetics. The physiologic effect of Methyl Paraben is by means of increased histamine release, and cell-mediated immunity. | |||||||||||||||||||||
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References
- [1]. Soni MG, et al. Evaluation of the health aspects of methyl paraben: a review of the published literature. Food Chem Toxicol. 2002 Oct;40(10):1335-73. [Content Brief]
- [2]. Elmore SE, et al. Disruption of normal adipocyte development and function by methyl- and propyl- paraben exposure. Toxicol Lett. 2020 Nov 1;334:27-35. [Content Brief]
- [3]. Kopalli SR, et al. Methylparaben protects 6-hydroxydopamine-induced neurotoxicity in SH-SY5Y cells and improved behavioral impairments in mouse model of Parkinson's disease. Neurotoxicology. 2013 Jan;34:25-32. [Content Brief]
- [4]. Gal A, et al. Propylparaben inhibits mouse cultured antral follicle growth, alters steroidogenesis, and upregulates levels of cell-cycle and apoptosis regulators. Reprod Toxicol. 2019 Oct;89:100-106. [Content Brief]
