P4HA3 Antibody (YA7828)

Cat. No.: HY-P88144: Data Sheet User Guide for Antibodies
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P4HA3 Antibody (YA7828) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to P4HA3.

For research use only. We do not sell to patients.

Size	Price	Stock
20 μL		Ask For Quote & Lead Time
50 μL		Ask For Quote & Lead Time
100 μL		Ask For Quote & Lead Time

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

P4HA3 Antibody (YA7828) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to P4HA3.

Host

Mouse

Clonality

Monoclonal

Molecular Weight

Predicted band size: 59.3 kDa

Species Reactivity

Human, Mouse, Rat

SwissProt ID

Q7Z4N8

Immunogen

Full length human recombiant protein of human P4HA3 produced in E.coli.

Application &
Dilution Ratio

Application	Dilution Ratio
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:800-1500

Sensitivity	Endogenous	Purity	Affinity purified
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG1

Appearance

Liquid

Formulation

Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins

Subcellular Localization：Endoplasmic reticulum lumen

Expression：
Tissue_Specificity: Highly expressed in placenta, liver and fetal skin. Weakly expressed in fetal epiphyseal cartilage, fetal liver, fibroblast, lung and skeletal muscle. Expressed also in fibrous cap of carotid atherosclerotic lesions

Isoforms & Post-Translational Modification：Q7Z4N8 has three isomers: Q7Z4N8-1: 61126 Da (predicted); Q7Z4N8-2: 28701 Da (predicted); Q7Z4N8-3: 67591 Da (predicted).
N-glycosylation plays no role in the catalytic activity

Subunit：Heterotetramer of two alpha-3 chains and two beta chains (the beta chain is the multi-functional PDI)

Synonyms

2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase); alpha III subunit; alpha polypeptide III; C-P4H alpha III; collagen prolyl 4-hydroxylase alpha(III); procollagen-proline; prolyl 4-hydroxylase

Documentation

User Guide for Antibodies (1077 KB)